메뉴 건너뛰기




Volumn , Issue , 2013, Pages 103-119

Interaction of Leishmania Parasites with Host Cells and its Functional Consequences

Author keywords

Dendritic cell; Drug discovery; Host cell interaction; Leishmania; Life cycle; Macrophage; Neutrophil

Indexed keywords


EID: 84886568506     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527670383.ch6     Document Type: Chapter
Times cited : (2)

References (112)
  • 1
    • 34447264232 scopus 로고    scopus 로고
    • Transmission of Leishmania metacyclic promastigotes by phlebotomine sand flies
    • Bates, P.A. (2007) Transmission of Leishmania metacyclic promastigotes by phlebotomine sand flies. Int. J. Parasitol., 37, 1097-1106.
    • (2007) Int. J. Parasitol. , vol.37 , pp. 1097-1106
    • Bates, P.A.1
  • 2
    • 15544362205 scopus 로고    scopus 로고
    • Flow cytometric assessment of Leishmania spp metacyclic differentiation: validation by morphological features and specific markers
    • Saraiva, E.M., Pinto-da-Silva, L.H., Wanderley, J.L., Bonomo, A.C., Barcinski, M.A. et al. (2005) Flow cytometric assessment of Leishmania spp metacyclic differentiation: validation by morphological features and specific markers. Exp. Parasitol., 110, 39-47.
    • (2005) Exp. Parasitol. , vol.110 , pp. 39-47
    • Saraiva, E.M.1    Pinto-da-Silva, L.H.2    Wanderley, J.L.3    Bonomo, A.C.4    Barcinski, M.A.5
  • 3
    • 0024390249 scopus 로고
    • Metacyclogenesis in Leishmania promastigotes
    • Sacks, D.L. (1989) Metacyclogenesis in Leishmania promastigotes. Exp. Parasitol., 69, 100-103.
    • (1989) Exp. Parasitol. , vol.69 , pp. 100-103
    • Sacks, D.L.1
  • 4
    • 79955423676 scopus 로고    scopus 로고
    • Correlation of meta 1 expression with culture stage, cell morphology and infectivity in Leishmania (Leishmania) amazonensis promastigotes
    • Santos, M.G., Silva, M.F., Zampieri, R. A., Lafraia, R.M., and Floeter-Winter, L. M. (2011) Correlation of meta 1 expression with culture stage, cell morphology and infectivity in Leishmania (Leishmania) amazonensis promastigotes. Mem. Inst. Oswaldo Cruz, 106, 190-193.
    • (2011) Mem. Inst. Oswaldo Cruz , vol.106 , pp. 190-193
    • Santos, M.G.1    Silva, M.F.2    Zampieri, R.A.3    Lafraia, R.M.4    Floeter-Winter, L.M.5
  • 5
    • 77953487283 scopus 로고    scopus 로고
    • Kinetoplastid membrane protein-11 is present in promastigotes and amastigotes of Leishmania amazonensis and its surface expression increases during metacyclogenesis
    • Matos, D.C., Faccioli, L.A., Cysne-Finkelstein, L., Luca, P.M., Corte-Real, S. et al. (2010) Kinetoplastid membrane protein-11 is present in promastigotes and amastigotes of Leishmania amazonensis and its surface expression increases during metacyclogenesis. Mem. Inst. Oswaldo Cruz, 105, 341-347.
    • (2010) Mem. Inst. Oswaldo Cruz , vol.105 , pp. 341-347
    • Matos, D.C.1    Faccioli, L.A.2    Cysne-Finkelstein, L.3    Luca, P.M.4    Corte-Real, S.5
  • 6
    • 0031571866 scopus 로고    scopus 로고
    • Metacyclogenesis modulates the ability of Leishmania promastigotes to induce IL-12 production in human mononuclear cells
    • Sartori, A., Oliveira, M.A., Scott, P., and Trinchieri, G. (1997) Metacyclogenesis modulates the ability of Leishmania promastigotes to induce IL-12 production in human mononuclear cells. J. Immunol., 159, 2849-2857.
    • (1997) J. Immunol. , vol.159 , pp. 2849-2857
    • Sartori, A.1    Oliveira, M.A.2    Scott, P.3    Trinchieri, G.4
  • 7
    • 0027194355 scopus 로고
    • Leishmania pifanoi: kinetics of messenger RNA expression during amastigote to promastigote transformation in vitro
    • Campbell, S.M. and Rainey, P.M. (1993) Leishmania pifanoi: kinetics of messenger RNA expression during amastigote to promastigote transformation in vitro. Exp. Parasitol., 77, 1-12.
    • (1993) Exp. Parasitol. , vol.77 , pp. 1-12
    • Campbell, S.M.1    Rainey, P.M.2
  • 8
    • 12344258115 scopus 로고    scopus 로고
    • The expression of mannose receptors in skin fibroblast and their involvement in Leishmania (L.) amazonensis invasion
    • Hespanhol, R.C., de Nazare, C.S.M., Meuser, M.B., de Nazareth, S.L.M.M., and Corte-Real, S. (2005) The expression of mannose receptors in skin fibroblast and their involvement in Leishmania (L.) amazonensis invasion. J. Histochem. Cytochem., 53, 35-44.
    • (2005) J. Histochem. Cytochem. , vol.53 , pp. 35-44
    • Hespanhol, R.C.1    de Nazare, C.S.M.2    Meuser, M.B.3    de Nazareth, S.L.M.M.4    Corte-Real, S.5
  • 11
    • 79958265461 scopus 로고    scopus 로고
    • Platelet activation attracts a subpopulation of effector monocytes to sites ofLeishmania major infection
    • Goncalves, R., Zhang, X., Cohen, H., Debrabant, A., and Mosser, D.M. (2011) Platelet activation attracts a subpopulation of effector monocytes to sites ofLeishmania major infection. J. Exp. Med., 208, 1253-1265.
    • (2011) J. Exp. Med. , vol.208 , pp. 1253-1265
    • Goncalves, R.1    Zhang, X.2    Cohen, H.3    Debrabant, A.4    Mosser, D.M.5
  • 12
    • 77954037796 scopus 로고    scopus 로고
    • Keratinocytes determine Th1 immunity during early experimental leishmaniasis
    • Ehrchen, J.M., Roebrock, K., Foell, D., Nippe, N., von Stebut, E. et al. (2010) Keratinocytes determine Th1 immunity during early experimental leishmaniasis. PLoS Pathog., 6, e1000871.
    • (2010) PLoS Pathog. , vol.6
    • Ehrchen, J.M.1    Roebrock, K.2    Foell, D.3    Nippe, N.4    von Stebut, E.5
  • 13
    • 79960829290 scopus 로고    scopus 로고
    • Neutrophils in the activation and regulation of innate and adaptive immunity
    • Mantovani, A., Cassatella, M.A., Costantini, C., and Jaillon, S. (2011) Neutrophils in the activation and regulation of innate and adaptive immunity. Nat. Rev. Immunol., 11, 519-531.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 519-531
    • Mantovani, A.1    Cassatella, M.A.2    Costantini, C.3    Jaillon, S.4
  • 14
    • 0037674823 scopus 로고    scopus 로고
    • Neutrophil granulocytes - Trojan horses for Leishmania major and other intracellular microbes?
    • Laskay, T., van Zandbergen, G., and Solbach, W. (2003) Neutrophil granulocytes - Trojan horses for Leishmania major and other intracellular microbes? Trends Microbiol., 11, 210-214.
    • (2003) Trends Microbiol. , vol.11 , pp. 210-214
    • Laskay, T.1    van Zandbergen, G.2    Solbach, W.3
  • 15
    • 0036073210 scopus 로고    scopus 로고
    • Leishmania promastigotes release a granulocyte chemotactic factor and induce interleukin-8 release but inhibit gamma interferon-inducible protein 10 production by neutrophil granulocytes
    • van Zandbergen, G., Hermann, N., Laufs, H., Solbach,W., and Laskay, T. (2002) Leishmania promastigotes release a granulocyte chemotactic factor and induce interleukin-8 release but inhibit gamma interferon-inducible protein 10 production by neutrophil granulocytes. Infect. Immun., 70, 4177-4184.
    • (2002) Infect. Immun. , vol.70 , pp. 4177-4184
    • Van Zandbergen, G.1    Hermann, N.2    Laufs, H.3    Solbach, W.4    Laskay, T.5
  • 16
    • 49649116869 scopus 로고    scopus 로고
    • In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies
    • Peters, N.C., Egen, J.G., Secundino, N., Debrabant, A., and Kimblin, N. (2008) et al. In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies. Science, 321, 970-974.
    • (2008) Science , vol.321 , pp. 970-974
    • Peters, N.C.1    Egen, J.G.2    Secundino, N.3    Debrabant, A.4    Kimblin, N.5
  • 17
    • 0037100438 scopus 로고    scopus 로고
    • Inhibition of the spontaneous apoptosis of neutrophil granulocytes by the intracellular parasite Leishmania major
    • Aga, E., Katschinski, D.M., van Zandbergen, G., Laufs, H., Hansen, B. et al. (2002) Inhibition of the spontaneous apoptosis of neutrophil granulocytes by the intracellular parasite Leishmania major. J. Immunol., 169, 898-905.
    • (2002) J. Immunol. , vol.169 , pp. 898-905
    • Aga, E.1    Katschinski, D.M.2    van Zandbergen, G.3    Laufs, H.4    Hansen, B.5
  • 18
    • 36949038761 scopus 로고    scopus 로고
    • Trafficking of Leishmania donovani promastigotes in non-lytic compartments in neutrophils enables the subsequent transfer of parasites to macrophages
    • Gueirard, P., Laplante, A., Rondeau, C., Milon, G., and Desjardins, M. (2008) Trafficking of Leishmania donovani promastigotes in non-lytic compartments in neutrophils enables the subsequent transfer of parasites to macrophages. Cell. Microbiol., 10, 100-111.
    • (2008) Cell. Microbiol. , vol.10 , pp. 100-111
    • Gueirard, P.1    Laplante, A.2    Rondeau, C.3    Milon, G.4    Desjardins, M.5
  • 19
    • 33646895940 scopus 로고    scopus 로고
    • Macrophages induce neutrophil apoptosis through membrane TNF, a process amplified by Leishmania major
    • Allenbach, C., Zufferey, C., Perez, C., Launois, P., Mueller, C. et al. (2006) Macrophages induce neutrophil apoptosis through membrane TNF, a process amplified by Leishmania major. J. Immunol., 176, 6656-6664.
    • (2006) J. Immunol. , vol.176 , pp. 6656-6664
    • Allenbach, C.1    Zufferey, C.2    Perez, C.3    Launois, P.4    Mueller, C.5
  • 20
    • 48649090401 scopus 로고    scopus 로고
    • Interactions with apoptotic but not with necrotic neutrophils increase parasite burden in human macrophages infected with Leishmania amazonensis
    • Afonso, L., Borges, V.M., Cruz, H., Ribeiro-Gomes, F.L., DosReis, G.A. et al. (2008) Interactions with apoptotic but not with necrotic neutrophils increase parasite burden in human macrophages infected with Leishmania amazonensis. J. Leukoc. Biol., 84, 389-396.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 389-396
    • Afonso, L.1    Borges, V.M.2    Cruz, H.3    Ribeiro-Gomes, F.L.4    DosReis, G.A.5
  • 22
    • 9144220867 scopus 로고    scopus 로고
    • Cutting edge: neutrophil granulocyte serves as a vector for Leishmania entry into macrophages
    • van Zandbergen, G., Klinger, M., Mueller, A., Dannenberg, S., Gebert, A. et al. (2004) Cutting edge: neutrophil granulocyte serves as a vector for Leishmania entry into macrophages. J. Immunol., 173, 6521-6525.
    • (2004) J. Immunol. , vol.173 , pp. 6521-6525
    • van Zandbergen, G.1    Klinger, M.2    Mueller, A.3    Dannenberg, S.4    Gebert, A.5
  • 23
    • 78149474168 scopus 로고    scopus 로고
    • Neutrophils reduce the parasite burden in Leishmania (Leishmania) amazonensis-infected macrophages
    • de Souza Carmo, E.V., Katz, S., and Barbieri, C.L. (2010) Neutrophils reduce the parasite burden in Leishmania (Leishmania) amazonensis-infected macrophages. PLoS ONE, 5, e13815.
    • (2010) PLoS ONE , vol.5
    • de Souza Carmo, E.V.1    Katz, S.2    Barbieri, C.L.3
  • 24
    • 76249105131 scopus 로고    scopus 로고
    • Neutrophils and macrophages cooperate in host resistance against Leishmania braziliensis infection
    • Novais, F.O., Santiago, R.C., Bafica, A., Khouri, R., Afonso, L. et al. (2009) Neutrophils and macrophages cooperate in host resistance against Leishmania braziliensis infection. J. Immunol., 183, 8088-8098.
    • (2009) J. Immunol. , vol.183 , pp. 8088-8098
    • Novais, F.O.1    Santiago, R.C.2    Bafica, A.3    Khouri, R.4    Afonso, L.5
  • 25
    • 39149112800 scopus 로고    scopus 로고
    • Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani
    • McFarlane, E., Perez, C., Charmoy, M., Allenbach, C., Carter, K.C. et al. (2008) Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani. Infect. Immun., 76, 532-541.
    • (2008) Infect. Immun. , vol.76 , pp. 532-541
    • McFarlane, E.1    Perez, C.2    Charmoy, M.3    Allenbach, C.4    Carter, K.C.5
  • 26
    • 77958130620 scopus 로고    scopus 로고
    • Leishmania donovani promastigotes evade the antimicrobial activity of neutrophil extracellular traps
    • Gabriel, C., McMaster,W.R., Girard, D., and Descoteaux, A. (2010) Leishmania donovani promastigotes evade the antimicrobial activity of neutrophil extracellular traps. J. Immunol., 185, 4319-4327.
    • (2010) J. Immunol. , vol.185 , pp. 4319-4327
    • Gabriel, C.1    McMaster, W.R.2    Girard, D.3    Descoteaux, A.4
  • 28
    • 0032740614 scopus 로고    scopus 로고
    • Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL- production by targeting ERK MAP kinase
    • Feng, G.J., Goodridge, H.S., Harnett, M. M., Wei, X.Q., Nikolaev, A.V. et al. (1999) Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL- production by targeting ERK MAP kinase. J. Immunol., 163, 6403-6412.
    • (1999) J. Immunol. , vol.163 , pp. 6403-6412
    • Feng, G.J.1    Goodridge, H.S.2    Harnett, M.M.3    Wei, X.Q.4    Nikolaev, A.V.5
  • 29
    • 73349104941 scopus 로고    scopus 로고
    • Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases
    • Gomez, M.A., Contreras, I., Halle, M., Tremblay, M.L., McMaster, R.W. et al. (2009) Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases. Sci. Signal, 2, ra58.
    • (2009) Sci. Signal , vol.2
    • Gomez, M.A.1    Contreras, I.2    Halle, M.3    Tremblay, M.L.4    McMaster, R.W.5
  • 30
    • 77954686146 scopus 로고    scopus 로고
    • MAPK-directed phosphatases preferentially regulate pro- and antiinflammatory cytokines in experimental visceral leishmaniasis: involvement of distinct protein kinase C isoforms
    • Kar, S., Ukil, A., Sharma, G., and Das, P. K. (2010) MAPK-directed phosphatases preferentially regulate pro- and antiinflammatory cytokines in experimental visceral leishmaniasis: involvement of distinct protein kinase C isoforms. J. Leukoc. Biol., 88, 9-20.
    • (2010) J. Leukoc. Biol. , vol.88 , pp. 9-20
    • Kar, S.1    Ukil, A.2    Sharma, G.3    Das, P.K.4
  • 31
    • 38049177580 scopus 로고    scopus 로고
    • The major surface protease (MSP or GP63) in the intracellular amastigote stage of Leishmania chagasi
    • Hsiao, C.H., Yao, C., Storlie, P., Donelson, J.E., and Wilson, M.E. (2008) The major surface protease (MSP or GP63) in the intracellular amastigote stage of Leishmania chagasi. Mol. Biochem. Parasitol., 157, 148-159.
    • (2008) Mol. Biochem. Parasitol. , vol.157 , pp. 148-159
    • Hsiao, C.H.1    Yao, C.2    Storlie, P.3    Donelson, J.E.4    Wilson, M.E.5
  • 32
    • 0026918044 scopus 로고
    • Leishmania major: differential regulation of the surface metalloprotease in amastigote and promastigote stages
    • Schneider, P., Rosat, J.P., Bouvier, J., Louis, J., and Bordier, C. (1992) Leishmania major: differential regulation of the surface metalloprotease in amastigote and promastigote stages. Exp. Parasitol., 75, 196-206.
    • (1992) Exp. Parasitol. , vol.75 , pp. 196-206
    • Schneider, P.1    Rosat, J.P.2    Bouvier, J.3    Louis, J.4    Bordier, C.5
  • 33
    • 63849109119 scopus 로고    scopus 로고
    • Regulation of macrophage nitric oxide production by the protein tyrosine phosphatase Src homology 2 domain phosphotyrosine phosphatase 1 (SHP-1)
    • Blanchette, J., Abu-Dayyeh, I., Hassani, K., Whitcombe, L., and Olivier, M. (2009) Regulation of macrophage nitric oxide production by the protein tyrosine phosphatase Src homology 2 domain phosphotyrosine phosphatase 1 (SHP-1). Immunology, 127, 123-133.
    • (2009) Immunology , vol.127 , pp. 123-133
    • Blanchette, J.1    Abu-Dayyeh, I.2    Hassani, K.3    Whitcombe, L.4    Olivier, M.5
  • 34
    • 33750468333 scopus 로고    scopus 로고
    • Role of host protein tyrosine phosphatase SHP-1 in Leishmania donovani-induced inhibition of nitric oxide production
    • Forget, G., Gregory, D.J., Whitcombe, L. A., and Olivier, M. (2006) Role of host protein tyrosine phosphatase SHP-1 in Leishmania donovani-induced inhibition of nitric oxide production. Infect. Immun., 74, 6272-6279.
    • (2006) Infect. Immun. , vol.74 , pp. 6272-6279
    • Forget, G.1    Gregory, D.J.2    Whitcombe, L.A.3    Olivier, M.4
  • 35
    • 0029035476 scopus 로고
    • Altered immune responses in mice lacking inducible nitric oxide synthase
    • Wei, X.Q., Charles, I.G., Smith, A., Ure, J., Feng, G.J. et al. (1995) Altered immune responses in mice lacking inducible nitric oxide synthase. Nature, 375, 408-411.
    • (1995) Nature , vol.375 , pp. 408-411
    • Wei, X.Q.1    Charles, I.G.2    Smith, A.3    Ure, J.4    Feng, G.J.5
  • 36
    • 76249084931 scopus 로고    scopus 로고
    • Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokineindependent regulation of host cellular arginase activity and disease pathogenesis
    • Muleme, H.M., Reguera, R.M., Berard, A., Azinwi, R., Jia, P. et al. (2009) Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokineindependent regulation of host cellular arginase activity and disease pathogenesis. J. Immunol., 183, 8068-8076.
    • (2009) J. Immunol. , vol.183 , pp. 8068-8076
    • Muleme, H.M.1    Reguera, R.M.2    Berard, A.3    Azinwi, R.4    Jia, P.5
  • 37
    • 58149352480 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells
    • Schmitz, F., Heit, A., Dreher, S., Eisenacher, K., Mages, J. et al. (2008) Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells. Eur. J. Immunol., 38, 2981-2992.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2981-2992
    • Schmitz, F.1    Heit, A.2    Dreher, S.3    Eisenacher, K.4    Mages, J.5
  • 38
    • 84860553050 scopus 로고    scopus 로고
    • mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection
    • Cheekatla, S.S., Aggarwal, A., and Naik, S. (2012) mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection. Med. Microbiol. Immunol., 201, 37-46.
    • (2012) Med. Microbiol. Immunol. , vol.201 , pp. 37-46
    • Cheekatla, S.S.1    Aggarwal, A.2    Naik, S.3
  • 39
    • 33845447657 scopus 로고    scopus 로고
    • Leishmania promastigotes activate PI3K/Akt signalling to confer host cell resistance to apoptosis
    • Ruhland, A., Leal, N., and Kima, P.E. (2007) Leishmania promastigotes activate PI3K/Akt signalling to confer host cell resistance to apoptosis. Cell. Microbiol., 9, 84-96.
    • (2007) Cell. Microbiol. , vol.9 , pp. 84-96
    • Ruhland, A.1    Leal, N.2    Kima, P.E.3
  • 40
    • 64449084586 scopus 로고    scopus 로고
    • Activation of PI3K/Akt signaling has a dominant negative effect on IL-12 production by macrophages infected with Leishmania amazonensis promastigotes
    • Ruhland, A. and Kima, P.E. (2009) Activation of PI3K/Akt signaling has a dominant negative effect on IL-12 production by macrophages infected with Leishmania amazonensis promastigotes. Exp. Parasitol., 122, 28-36.
    • (2009) Exp. Parasitol. , vol.122 , pp. 28-36
    • Ruhland, A.1    Kima, P.E.2
  • 41
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta, S.R., Dudek, H., Tao, X., Masters, S., Fu, H. et al. (1997) Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell, 91, 231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5
  • 42
    • 67649607465 scopus 로고    scopus 로고
    • Autophagy, immunity, and microbial adaptations
    • Deretic, V. and Levine, B. (2009) Autophagy, immunity, and microbial adaptations. Cell Host Microbe, 5, 527-549.
    • (2009) Cell Host Microbe , vol.5 , pp. 527-549
    • Deretic, V.1    Levine, B.2
  • 43
    • 78651284554 scopus 로고    scopus 로고
    • The complexes of mammalian target of rapamycin
    • Zhou, H. and Huang, S. (2010) The complexes of mammalian target of rapamycin. Curr. Protein Pept. Sci., 11, 409-424.
    • (2010) Curr. Protein Pept. Sci. , vol.11 , pp. 409-424
    • Zhou, H.1    Huang, S.2
  • 44
    • 79955054747 scopus 로고    scopus 로고
    • Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection
    • Jaramillo, M., Gomez, M.A., Larsson, O., Shio, M.T., Topisirovic, I. et al. (2011) Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection. Cell Host Microbe, 9, 331-341.
    • (2011) Cell Host Microbe , vol.9 , pp. 331-341
    • Jaramillo, M.1    Gomez, M.A.2    Larsson, O.3    Shio, M.T.4    Topisirovic, I.5
  • 45
    • 61449199290 scopus 로고    scopus 로고
    • Induction of autophagy correlates with increased parasite load of Leishmania amazonensis in BALB/c but not C57BL/6 macrophages
    • Pinheiro, R.O., Nunes, M.P., Pinheiro, C. S., D'Avila, H., Bozza, P.T. et al. (2009) Induction of autophagy correlates with increased parasite load of Leishmania amazonensis in BALB/c but not C57BL/6 macrophages. Microbes Infect., 11, 181-190.
    • (2009) Microbes Infect. , vol.11 , pp. 181-190
    • Pinheiro, R.O.1    Nunes, M.P.2    Pinheiro, C.S.3    D'Avila, H.4    Bozza, P.T.5
  • 46
    • 0032996570 scopus 로고    scopus 로고
    • Parasitophorous vacuoles of Leishmania mexicana acquiremacromolecules from the host cell cytosol via two independent routes
    • Schaible, U.E., Schlesinger, P.H., Steinberg, T.H., Mangel, W.F., Kobayashi, T. et al. (1999) Parasitophorous vacuoles of Leishmania mexicana acquiremacromolecules from the host cell cytosol via two independent routes. J. Cell Sci., 112, 681-693.
    • (1999) J. Cell Sci. , vol.112 , pp. 681-693
    • Schaible, U.E.1    Schlesinger, P.H.2    Steinberg, T.H.3    Mangel, W.F.4    Kobayashi, T.5
  • 47
    • 78449240895 scopus 로고    scopus 로고
    • Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63
    • Contreras, I., Gomez, M.A., Nguyen, O., Shio, M.T., McMaster, R.W. et al. (2010) Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63. PLoS Pathog., 6, e1001148.
    • (2010) PLoS Pathog. , vol.6
    • Contreras, I.1    Gomez, M.A.2    Nguyen, O.3    Shio, M.T.4    McMaster, R.W.5
  • 48
    • 44849118269 scopus 로고    scopus 로고
    • A novel form of NF-kappaB is induced by Leishmania infection: involvement in macrophage gene expression
    • Gregory, D.J., Godbout, M., Contreras, I., Forget, G., and Olivier, M. (2008) A novel form of NF-kappaB is induced by Leishmania infection: involvement in macrophage gene expression. Eur. J. Immunol., 38, 1071-1081.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 1071-1081
    • Gregory, D.J.1    Godbout, M.2    Contreras, I.3    Forget, G.4    Olivier, M.5
  • 49
    • 4344613395 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway
    • Cameron, P., McGachy, A., Anderson, M., Paul, A., Coombs, G.H. et al. (2004) Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway. J. Immunol., 173, 3297-3304.
    • (2004) J. Immunol. , vol.173 , pp. 3297-3304
    • Cameron, P.1    McGachy, A.2    Anderson, M.3    Paul, A.4    Coombs, G.H.5
  • 50
    • 0344643400 scopus 로고    scopus 로고
    • Activation of TGF-beta by Leishmania chagasi: importance for parasite survival in macrophages
    • Gantt, K.R., Schultz-Cherry, S., Rodriguez, N., Jeronimo, S.M., Nascimento, E.T. et al. (2003) Activation of TGF-beta by Leishmania chagasi: importance for parasite survival in macrophages. J. Immunol., 170, 2613-2620.
    • (2003) J. Immunol. , vol.170 , pp. 2613-2620
    • Gantt, K.R.1    Schultz-Cherry, S.2    Rodriguez, N.3    Jeronimo, S.M.4    Nascimento, E.T.5
  • 51
    • 0037067762 scopus 로고    scopus 로고
    • Functional analysis of cathepsin B-like cysteine proteases from Leishmania donovani complex. Evidence for the activation of latent transforming growth factor beta
    • Somanna, A., Mundodi, V., and Gedamu, L. (2002) Functional analysis of cathepsin B-like cysteine proteases from Leishmania donovani complex. Evidence for the activation of latent transforming growth factor beta. J. Biol. Chem., 277, 25305-25312.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25305-25312
    • Somanna, A.1    Mundodi, V.2    Gedamu, L.3
  • 52
    • 47849088781 scopus 로고    scopus 로고
    • A Leishmania ortholog of macrophage migration inhibitory factor modulates host macrophage responses
    • Kamir, D., Zierow, S., Leng, L., Cho, Y., Diaz, Y. et al. (2008) A Leishmania ortholog of macrophage migration inhibitory factor modulates host macrophage responses. J. Immunol., 180, 8250-8261.
    • (2008) J. Immunol. , vol.180 , pp. 8250-8261
    • Kamir, D.1    Zierow, S.2    Leng, L.3    Cho, Y.4    Diaz, Y.5
  • 53
    • 0035143587 scopus 로고    scopus 로고
    • Migration-inhibitory factor gene-deficient mice are susceptible to cutaneous Leishmania major infection
    • Satoskar, A.R., Bozza, M., Rodriguez Sosa, M., Lin, G., and David, J.R. (2001) Migration-inhibitory factor gene-deficient mice are susceptible to cutaneous Leishmania major infection. Infect. Immun., 69, 906-911.
    • (2001) Infect. Immun. , vol.69 , pp. 906-911
    • Satoskar, A.R.1    Bozza, M.2    Rodriguez Sosa, M.3    Lin, G.4    David, J.R.5
  • 54
    • 0032167393 scopus 로고    scopus 로고
    • Migration inhibitory factor induces killing of Leishmania major by macrophages: dependence on reactive nitrogen intermediates and endogenous TNFalpha
    • Juttner, S., Bernhagen, J., Metz, C.N., Röllinghoff, M., Bucala, R. et al. (1998) Migration inhibitory factor induces killing of Leishmania major by macrophages: dependence on reactive nitrogen intermediates and endogenous TNFalpha. J. Immunol., 161, 2383-2390.
    • (1998) J. Immunol. , vol.161 , pp. 2383-2390
    • Juttner, S.1    Bernhagen, J.2    Metz, C.N.3    Röllinghoff, M.4    Bucala, R.5
  • 55
    • 78449236372 scopus 로고    scopus 로고
    • Identification of Leishmania proteins preferentially released in infected cells using change mediated antigen technology (CMAT)
    • Kima, P.E., Bonilla, J.A., Cho, E., Ndjamen, B., Canton, J. et al. (2010) Identification of Leishmania proteins preferentially released in infected cells using change mediated antigen technology (CMAT). PLoS Negl. Trop. Dis., 4, e842.
    • (2010) PLoS Negl. Trop. Dis. , vol.4
    • Kima, P.E.1    Bonilla, J.A.2    Cho, E.3    Ndjamen, B.4    Canton, J.5
  • 56
    • 0028100782 scopus 로고
    • Leishmania donovaniinfected macrophages: characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentation
    • Lang, T., Hellio, R., Kaye, P.M., and Antoine, J.C. (1994) Leishmania donovaniinfected macrophages: characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentation. J. Cell. Sci., 107, 2137-2150.
    • (1994) J. Cell. Sci. , vol.107 , pp. 2137-2150
    • Lang, T.1    Hellio, R.2    Kaye, P.M.3    Antoine, J.C.4
  • 57
    • 33846959492 scopus 로고    scopus 로고
    • The ultrastructure of the parasitophorous vacuole formed by Leishmania major
    • Castro, R., Scott, K., Jordan, T., Evans, B., Craig, J. et al. (2006) The ultrastructure of the parasitophorous vacuole formed by Leishmania major. J. Parasitol., 92, 1162-1170.
    • (2006) J. Parasitol. , vol.92 , pp. 1162-1170
    • Castro, R.1    Scott, K.2    Jordan, T.3    Evans, B.4    Craig, J.5
  • 58
    • 0029155778 scopus 로고
    • Intracellular Leishmania amazonensis amastigotes internalize and degrade MHC class II molecules of their host cells
    • De Souza Leao, S., Lang, T., Prina, E., Hellio, R., and Antoine, J.C. (1995) Intracellular Leishmania amazonensis amastigotes internalize and degrade MHC class II molecules of their host cells. J. Cell Sci., 108, 3219-3231.
    • (1995) J. Cell Sci. , vol.108 , pp. 3219-3231
    • De Souza Leao, S.1    Lang, T.2    Prina, E.3    Hellio, R.4    Antoine, J.C.5
  • 59
    • 0032814383 scopus 로고    scopus 로고
    • H-2M molecules, like MHC class II molecules, are targeted to parasitophorous vacuoles of Leishmania-infected macrophages and internalized by amastigotes of L. amazonensis and L. mexicana
    • Antoine, J.C., Lang, T., Prina, E., Courret, N., and Hellio, R. (1999) H-2M molecules, like MHC class II molecules, are targeted to parasitophorous vacuoles of Leishmania-infected macrophages and internalized by amastigotes of L. amazonensis and L. mexicana. J. Cell Sci., 112, 2559-2570.
    • (1999) J. Cell Sci. , vol.112 , pp. 2559-2570
    • Antoine, J.C.1    Lang, T.2    Prina, E.3    Courret, N.4    Hellio, R.5
  • 60
    • 0027095665 scopus 로고
    • Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages
    • Russell, D.G., Xu, S., and Chakraborty, P. (1992) Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages. J. Cell Sci., 103, 1193-1210.
    • (1992) J. Cell Sci. , vol.103 , pp. 1193-1210
    • Russell, D.G.1    Xu, S.2    Chakraborty, P.3
  • 61
    • 0022596199 scopus 로고
    • Destruction of Leishmania mexicana amazonensis amastigotes within macrophages by lysosomotropic amino acid esters
    • Rabinovitch, M., Zilberfarb, V., and Ramazeilles, C. (1986) Destruction of Leishmania mexicana amazonensis amastigotes within macrophages by lysosomotropic amino acid esters. J. Exp. Med., 163, 520-535.
    • (1986) J. Exp. Med. , vol.163 , pp. 520-535
    • Rabinovitch, M.1    Zilberfarb, V.2    Ramazeilles, C.3
  • 62
    • 0025098455 scopus 로고
    • Parasitophorous vacuoles of Leishmania amazonensisinfected macrophages maintain an acidic pH
    • Antoine, J.C., Prina, E., Jouanne, C., and Bongrand, P. (1990) Parasitophorous vacuoles of Leishmania amazonensisinfected macrophages maintain an acidic pH. Infect. Immun., 58, 779-787.
    • (1990) Infect. Immun. , vol.58 , pp. 779-787
    • Antoine, J.C.1    Prina, E.2    Jouanne, C.3    Bongrand, P.4
  • 63
    • 0036152823 scopus 로고    scopus 로고
    • +-ATPase regulates intracellular pH in Leishmania mexicana amazonensis
    • +-ATPase regulates intracellular pH in Leishmania mexicana amazonensis. Mol. Biochem. Parasitol., 119, 225-236.
    • (2002) Mol. Biochem. Parasitol. , vol.119 , pp. 225-236
    • Marchesini, N.1    Docampo, R.2
  • 65
    • 79960561011 scopus 로고    scopus 로고
    • Leishmania major: activity of tamoxifen against experimental cutaneous leishmaniasis
    • Eissa, M.M., Amer, E.I., and El Sawy, S.M. (2011) Leishmania major: activity of tamoxifen against experimental cutaneous leishmaniasis. Exp. Parasitol., 128, 382-390.
    • (2011) Exp. Parasitol. , vol.128 , pp. 382-390
    • Eissa, M.M.1    Amer, E.I.2    El Sawy, S.M.3
  • 66
    • 34548136191 scopus 로고    scopus 로고
    • Tamoxifen is effective against Leishmania and induces a rapid alkalinization of parasitophorous vacuoles harbouring Leishmania (Leishmania) amazonensis amastigotes
    • Miguel, D.C., Yokoyama-Yasunaka, J.K., Andreoli,W.K., Mortara, R.A., and Uliana, S.R. (2007) Tamoxifen is effective against Leishmania and induces a rapid alkalinization of parasitophorous vacuoles harbouring Leishmania (Leishmania) amazonensis amastigotes. J. Antimicrob. Chemother., 60, 526-534.
    • (2007) J. Antimicrob. Chemother. , vol.60 , pp. 526-534
    • Miguel, D.C.1    Yokoyama-Yasunaka, J.K.2    Andreoli, W.K.3    Mortara, R.A.4    Uliana, S.R.5
  • 67
    • 48949118061 scopus 로고    scopus 로고
    • Tamoxifen is effective in the treatment of Leishmania amazonensis infections in mice
    • Miguel, D.C., Yokoyama-Yasunaka, J.K., and Uliana, S.R. (2008) Tamoxifen is effective in the treatment of Leishmania amazonensis infections in mice. PLoS Negl. Trop. Dis., 2, e249.
    • (2008) PLoS Negl. Trop. Dis. , vol.2
    • Miguel, D.C.1    Yokoyama-Yasunaka, J.K.2    Uliana, S.R.3
  • 68
    • 58849145630 scopus 로고    scopus 로고
    • Tamoxifen as a potential antileishmanial agent: efficacy in the treatment of Leishmania braziliensis and Leishmania chagasi infections
    • Miguel, D.C., Zauli-Nascimento, R.C., Yokoyama-Yasunaka, J.K., Katz, S., Barbieri, C.L. et al. (2009) Tamoxifen as a potential antileishmanial agent: efficacy in the treatment of Leishmania braziliensis and Leishmania chagasi infections. J. Antimicrob. Chemother., 63, 365-368.
    • (2009) J. Antimicrob. Chemother. , vol.63 , pp. 365-368
    • Miguel, D.C.1    Zauli-Nascimento, R.C.2    Yokoyama-Yasunaka, J.K.3    Katz, S.4    Barbieri, C.L.5
  • 69
    • 0027487850 scopus 로고
    • Regulation of L-proline transport in Leishmania donovani by extracellular pH
    • Zilberstein, D. and Gepstein, A. (1993) Regulation of L-proline transport in Leishmania donovani by extracellular pH. Mol. Biochem. Parasitol., 61, 197-205.
    • (1993) Mol. Biochem. Parasitol. , vol.61 , pp. 197-205
    • Zilberstein, D.1    Gepstein, A.2
  • 70
    • 0029563799 scopus 로고
    • Glucose transport in amastigotes and promastigotes of Leishmania mexicana mexicana
    • Burchmore, R.J. and Hart, D.T. (1995) Glucose transport in amastigotes and promastigotes of Leishmania mexicana mexicana. Mol. Biochem. Parasitol., 74, 77-86.
    • (1995) Mol. Biochem. Parasitol. , vol.74 , pp. 77-86
    • Burchmore, R.J.1    Hart, D.T.2
  • 71
  • 72
    • 0025345363 scopus 로고
    • Localization and activity of various lysosomal proteases in Leishmania amazonensis-infected macrophages
    • Prina, E., Antoine, J.C., Wiederanders, B., and Kirschke, H. (1990) Localization and activity of various lysosomal proteases in Leishmania amazonensis-infected macrophages. Infect. Immun., 58, 1730-1737.
    • (1990) Infect. Immun. , vol.58 , pp. 1730-1737
    • Prina, E.1    Antoine, J.C.2    Wiederanders, B.3    Kirschke, H.4
  • 73
    • 0036591962 scopus 로고    scopus 로고
    • Biogenesis of Leishmania-harbouring parasitophorous vacuoles following phagocytosis of the metacyclic promastigote or amastigote stages of the parasites
    • Courret, N., Frehel, C., Gouhier, N., Pouchelet, M., Prina, E. et al. (2002) Biogenesis of Leishmania-harbouring parasitophorous vacuoles following phagocytosis of the metacyclic promastigote or amastigote stages of the parasites. J. Cell Sci., 115, 2303-2316.
    • (2002) J. Cell Sci. , vol.115 , pp. 2303-2316
    • Courret, N.1    Frehel, C.2    Gouhier, N.3    Pouchelet, M.4    Prina, E.5
  • 74
    • 27744530918 scopus 로고    scopus 로고
    • Leishmania donovani amastigotes mobilize organic and inorganic osmolytes during regulatory volume decrease
    • Lefurgey, A., Gannon, M., Blum, J., and Ingram, P. (2005) Leishmania donovani amastigotes mobilize organic and inorganic osmolytes during regulatory volume decrease. J. Eukaryot. Microbiol., 52, 277-289.
    • (2005) J. Eukaryot. Microbiol. , vol.52 , pp. 277-289
    • Lefurgey, A.1    Gannon, M.2    Blum, J.3    Ingram, P.4
  • 75
    • 0022413168 scopus 로고
    • The mouse macrophage receptor for C3bi (CR3) is a major mechanism in the phagocytosis of Leishmania promastigotes
    • Mosser, D.M. and Edelson, P.J. (1985) The mouse macrophage receptor for C3bi (CR3) is a major mechanism in the phagocytosis of Leishmania promastigotes. J. Immunol., 135, 2785-2789.
    • (1985) J. Immunol. , vol.135 , pp. 2785-2789
    • Mosser, D.M.1    Edelson, P.J.2
  • 76
    • 0023118494 scopus 로고
    • Increased infectivity of stationaryphase promastigotes of Leishmania donovani: correlation with enhanced C3 binding capacity and CR3-mediated attachment to host macrophages
    • Wozencraft, A.O. and Blackwell, J.M. (1987) Increased infectivity of stationaryphase promastigotes of Leishmania donovani: correlation with enhanced C3 binding capacity and CR3-mediated attachment to host macrophages. Immunology, 60, 559-563.
    • (1987) Immunology , vol.60 , pp. 559-563
    • Wozencraft, A.O.1    Blackwell, J.M.2
  • 77
    • 0022481293 scopus 로고
    • Macrophage type 3 complement receptors mediate serumindependent binding of Leishmania donovani. Detection of macrophagederived complement on the parasite surface by immunoelectron microscopy
    • Wozencraft, A.O., Sayers, G., and Blackwell, J.M. (1986) Macrophage type 3 complement receptors mediate serumindependent binding of Leishmania donovani. Detection of macrophagederived complement on the parasite surface by immunoelectron microscopy. J. Exp. Med., 164, 1332-1337.
    • (1986) J. Exp. Med. , vol.164 , pp. 1332-1337
    • Wozencraft, A.O.1    Sayers, G.2    Blackwell, J.M.3
  • 78
    • 0025303476 scopus 로고
    • Lipophosphoglycan from Leishmania mexicana promastigotes binds to members of the CR3, p150, 95 and LFA-1 family of leukocyte integrins
    • Talamas-Rohana, P., Wright, S.D., Lennartz, M.R., and Russell, D.G. (1990) Lipophosphoglycan from Leishmania mexicana promastigotes binds to members of the CR3, p150, 95 and LFA-1 family of leukocyte integrins. J. Immunol., 144, 4817-4824.
    • (1990) J. Immunol. , vol.144 , pp. 4817-4824
    • Talamas-Rohana, P.1    Wright, S.D.2    Lennartz, M.R.3    Russell, D.G.4
  • 79
    • 0024340791 scopus 로고
    • CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages
    • Da Silva, R.P., Hall, B.F., Joiner, K.A., and Sacks, D.L. (1989) CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages. J. Immunol., 143, 617-622.
    • (1989) J. Immunol. , vol.143 , pp. 617-622
    • Da Silva, R.P.1    Hall, B.F.2    Joiner, K.A.3    Sacks, D.L.4
  • 80
    • 79955717508 scopus 로고    scopus 로고
    • Stage-specific pathways of Leishmania infantum chagasi entry and phagosome maturation in macrophages
    • Rodriguez, N.E., Gaur Dixit, U., Allen, L. A., and Wilson, M.E. (2011) Stage-specific pathways of Leishmania infantum chagasi entry and phagosome maturation in macrophages. PLoS ONE, 6, e19000.
    • (2011) PLoS ONE , vol.6
    • Rodriguez, N.E.1    Gaur Dixit, U.2    Allen, L.A.3    Wilson, M.E.4
  • 81
    • 0034085602 scopus 로고    scopus 로고
    • Leishmania promastigotes require lipophosphoglycan to actively modulate the fusion properties of phagosomes at an early step of phagocytosis
    • Dermine, J.F., Scianimanico, S., Prive, C., Descoteaux, A., and Desjardins, M. (2000) Leishmania promastigotes require lipophosphoglycan to actively modulate the fusion properties of phagosomes at an early step of phagocytosis. Cell. Microbiol., 2, 115-126.
    • (2000) Cell. Microbiol. , vol.2 , pp. 115-126
    • Dermine, J.F.1    Scianimanico, S.2    Prive, C.3    Descoteaux, A.4    Desjardins, M.5
  • 82
    • 0034255342 scopus 로고    scopus 로고
    • Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major
    • Späth, G.F., Epstein, L., Leader, B., Singer, S.M., Avila, H.A. et al. (2000) Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major. Proc. Natl. Acad. Sci. USA, 97, 9258-9263.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9258-9263
    • Späth, G.F.1    Epstein, L.2    Leader, B.3    Singer, S.M.4    Avila, H.A.5
  • 83
    • 0027483033 scopus 로고
    • Comparison of receptors required for entry of Leishmania major amastigotes into macrophages
    • Guy, R.A. and Belosevic, M. (1993) Comparison of receptors required for entry of Leishmania major amastigotes into macrophages. Infect. Immun., 61, 1553-1558.
    • (1993) Infect. Immun. , vol.61 , pp. 1553-1558
    • Guy, R.A.1    Belosevic, M.2
  • 84
    • 0029585453 scopus 로고
    • The role of macrophage receptors in adhesion and uptake of Leishmania mexicana amastigotes
    • Peters, C., Aebischer, T., Stierhof, Y.D., Fuchs, M., and Overath, P. (1995) The role of macrophage receptors in adhesion and uptake of Leishmania mexicana amastigotes. J. Cell Sci., 108, 3715-3724.
    • (1995) J. Cell Sci. , vol.108 , pp. 3715-3724
    • Peters, C.1    Aebischer, T.2    Stierhof, Y.D.3    Fuchs, M.4    Overath, P.5
  • 85
    • 0031005660 scopus 로고    scopus 로고
    • Inhibition of phagolysosomal biogenesis by the Leishmania lipophosphoglycan
    • Desjardins, M. and Descoteaux, A. (1997) Inhibition of phagolysosomal biogenesis by the Leishmania lipophosphoglycan. J. Exp. Med., 185, 2061-2068.
    • (1997) J. Exp. Med. , vol.185 , pp. 2061-2068
    • Desjardins, M.1    Descoteaux, A.2
  • 86
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J. and Steinman, R.M. (1998) Dendritic cells and the control of immunity. Nature, 392, 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 87
    • 33644828391 scopus 로고    scopus 로고
    • Development of dendritic cell system
    • Wu, L. and Dakic, A. (2004) Development of dendritic cell system. Cell. Mol. Immunol., 1, 112-118.
    • (2004) Cell. Mol. Immunol. , vol.1 , pp. 112-118
    • Wu, L.1    Dakic, A.2
  • 88
    • 73949099057 scopus 로고    scopus 로고
    • The prominent role of neutrophils during the initial phase of infection by Leishmania parasites
    • Charmoy, M., Auderset, F., Allenbach, C., and Tacchini-Cottier, F. (2010) The prominent role of neutrophils during the initial phase of infection by Leishmania parasites. J. Biomed. Biotechnol., 2010, 719361.
    • (2010) J. Biomed. Biotechnol. , vol.2010 , pp. 719361
    • Charmoy, M.1    Auderset, F.2    Allenbach, C.3    Tacchini-Cottier, F.4
  • 89
    • 0034689004 scopus 로고    scopus 로고
    • The formation of immunogenic major histocompatibility complex class IIpeptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli
    • Inaba, K., Turley, S., Iyoda, T., Yamaide, F., Shimoyama, S. et al. (2000) The formation of immunogenic major histocompatibility complex class IIpeptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. J. Exp. Med., 191, 927-936.
    • (2000) J. Exp. Med. , vol.191 , pp. 927-936
    • Inaba, K.1    Turley, S.2    Iyoda, T.3    Yamaide, F.4    Shimoyama, S.5
  • 90
    • 0034278725 scopus 로고    scopus 로고
    • Dendritic cell regulation of TH1-TH2 development
    • Moser, M. and Murphy, K.M. (2000) Dendritic cell regulation of TH1-TH2 development. Nat. Immunol., 1, 199-205.
    • (2000) Nat. Immunol. , vol.1 , pp. 199-205
    • Moser, M.1    Murphy, K.M.2
  • 91
    • 31344442771 scopus 로고    scopus 로고
    • Uptake of Leishmania major by dendritic cells is mediated by Fcgamma receptors and facilitates acquisition of protective immunity
    • Woelbing, F., Kostka, S.L., Moelle, K., Belkaid, Y., Sunderkoetter, C. et al. (2006) Uptake of Leishmania major by dendritic cells is mediated by Fcgamma receptors and facilitates acquisition of protective immunity. J. Exp. Med., 203, 177-188.
    • (2006) J. Exp. Med. , vol.203 , pp. 177-188
    • Woelbing, F.1    Kostka, S.L.2    Moelle, K.3    Belkaid, Y.4    Sunderkoetter, C.5
  • 92
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • Sacks, D. and Noben-Trauth, N. (2002) The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol., 2, 845-858.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 93
    • 0030932976 scopus 로고    scopus 로고
    • Behavior of visceral Leishmania donovani in an experimentally induced T helper cell 2 (Th2)-associated response model
    • Murray, H.W., Hariprashad, J., and Coffman, R.L. (1997) Behavior of visceral Leishmania donovani in an experimentally induced T helper cell 2 (Th2)-associated response model. J. Exp. Med., 185, 867-874.
    • (1997) J. Exp. Med. , vol.185 , pp. 867-874
    • Murray, H.W.1    Hariprashad, J.2    Coffman, R.L.3
  • 94
    • 0035863867 scopus 로고    scopus 로고
    • The role of IL-10 in promoting disease progression in leishmaniasis
    • Kane, M.M. and Mosser, D.M. (2001) The role of IL-10 in promoting disease progression in leishmaniasis. J. Immunol., 166, 1141-1147.
    • (2001) J. Immunol. , vol.166 , pp. 1141-1147
    • Kane, M.M.1    Mosser, D.M.2
  • 95
    • 30744477705 scopus 로고    scopus 로고
    • Impairment of alternative macrophage activation delays cutaneous leishmaniasis in nonhealing BALB/c mice
    • Holscher, C., Arendse, B., Schwegmann, A., Myburgh, E., and Brombacher, F. (2006) Impairment of alternative macrophage activation delays cutaneous leishmaniasis in nonhealing BALB/c mice. J. Immunol., 176, 1115-1121.
    • (2006) J. Immunol. , vol.176 , pp. 1115-1121
    • Holscher, C.1    Arendse, B.2    Schwegmann, A.3    Myburgh, E.4    Brombacher, F.5
  • 96
    • 0033214545 scopus 로고    scopus 로고
    • Th1/ Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells
    • Munder, M., Eichmann, K., Moran, J.M., Centeno, F., Soler, G. et al. (1999) Th1/ Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells. J. Immunol., 163, 3771-3777.
    • (1999) J. Immunol. , vol.163 , pp. 3771-3777
    • Munder, M.1    Eichmann, K.2    Moran, J.M.3    Centeno, F.4    Soler, G.5
  • 97
    • 2542428547 scopus 로고    scopus 로고
    • Arginase plays a pivotal role in polyamine precursor metabolism in Leishmania. Characterization of gene deletion mutants
    • Roberts, S.C., Tancer, M.J., Polinsky, M. R., Gibson, K.M., Heby, O. et al. (2004) Arginase plays a pivotal role in polyamine precursor metabolism in Leishmania. Characterization of gene deletion mutants. J. Biol. Chem., 279, 23668-23678.
    • (2004) J. Biol. Chem. , vol.279 , pp. 23668-23678
    • Roberts, S.C.1    Tancer, M.J.2    Polinsky, M.R.3    Gibson, K.M.4    Heby, O.5
  • 98
    • 0037090268 scopus 로고    scopus 로고
    • + Tcells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major
    • + Tcells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major. J. Immunol., 168, 3992-4000.
    • (2002) J. Immunol. , vol.168 , pp. 3992-4000
    • Belkaid, Y.1    Von Stebut, E.2    Mendez, S.3    Lira, R.4    Caler, E.5
  • 101
    • 57149117827 scopus 로고    scopus 로고
    • Migratory dermal dendritic cells act as rapid sensors of protozoan parasites
    • Ng, L.G., Hsu, A., Mandell, M.A., Roediger, B., Hoeller, C. et al. (2008) Migratory dermal dendritic cells act as rapid sensors of protozoan parasites. PLoS Pathog., 4, e1000222.
    • (2008) PLoS Pathog. , vol.4
    • Ng, L.G.1    Hsu, A.2    Mandell, M.A.3    Roediger, B.4    Hoeller, C.5
  • 102
    • 0027473217 scopus 로고
    • Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major
    • Blank, C., Fuchs, H., Rappersberger, K., Röllinghoff, M., and Moll, H. (1993) Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major. J. Infect. Dis., 167, 418-425.
    • (1993) J. Infect. Dis. , vol.167 , pp. 418-425
    • Blank, C.1    Fuchs, H.2    Rappersberger, K.3    Röllinghoff, M.4    Moll, H.5
  • 103
    • 0035076991 scopus 로고    scopus 로고
    • Silent infection of bone marrow-derived dendritic cells by Leishmania mexicana amastigotes
    • Bennett, C.L., Misslitz, A., Colledge, L., Aebischer, T., and Blackburn, C.C. (2001) Silent infection of bone marrow-derived dendritic cells by Leishmania mexicana amastigotes. Eur. J. Immunol., 31, 876-883.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 876-883
    • Bennett, C.L.1    Misslitz, A.2    Colledge, L.3    Aebischer, T.4    Blackburn, C.C.5
  • 104
    • 1642495738 scopus 로고    scopus 로고
    • The dendritic cell receptor DC-SIGN discriminates among species and life cycle forms of Leishmania
    • Colmenares, M., Corbi, A.L., Turco, S.J., and Rivas, L. (2004) The dendritic cell receptor DC-SIGN discriminates among species and life cycle forms of Leishmania. J. Immunol., 172, 1186-1190.
    • (2004) J. Immunol. , vol.172 , pp. 1186-1190
    • Colmenares, M.1    Corbi, A.L.2    Turco, S.J.3    Rivas, L.4
  • 105
    • 0036151291 scopus 로고    scopus 로고
    • Leishmania major promastigotes inhibit dendritic cell motility in vitro
    • Jebbari, H., Stagg, A.J., Davidson, R.N., and Knight, S.C. (2002) Leishmania major promastigotes inhibit dendritic cell motility in vitro. Infect. Immun., 70, 1023-1026.
    • (2002) Infect. Immun. , vol.70 , pp. 1023-1026
    • Jebbari, H.1    Stagg, A.J.2    Davidson, R.N.3    Knight, S.C.4
  • 106
    • 0035674639 scopus 로고    scopus 로고
    • Leishmania major lipophosphoglycan modulates the phenotype and inhibits migration of murine Langerhans cells
    • Ponte-Sucre, A., Heise, D., and Moll, H. (2001) Leishmania major lipophosphoglycan modulates the phenotype and inhibits migration of murine Langerhans cells. Immunology, 104, 462-467.
    • (2001) Immunology , vol.104 , pp. 462-467
    • Ponte-Sucre, A.1    Heise, D.2    Moll, H.3
  • 107
    • 0028949382 scopus 로고
    • Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific Tcell immune response
    • Moll, H., Flohé, S., and Röllinghoff, M. (1995) Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific Tcell immune response. Eur. J. Immunol., 25, 693-699.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 693-699
    • Moll, H.1    Flohé, S.2    Röllinghoff, M.3
  • 108
    • 31844450727 scopus 로고    scopus 로고
    • Biogenesis of Leishmania major-harboring vacuoles in murine dendritic cells
    • Körner, U., Fuss, V., Steigerwald, J., and Moll, H. (2006) Biogenesis of Leishmania major-harboring vacuoles in murine dendritic cells. Infect. Immun., 74, 1305-1312.
    • (2006) Infect. Immun. , vol.74 , pp. 1305-1312
    • Körner, U.1    Fuss, V.2    Steigerwald, J.3    Moll, H.4
  • 109
    • 65649113275 scopus 로고    scopus 로고
    • Altered dendritic cell phenotype in response to Leishmania amazonensis amastigote infection is mediated by MAP kinase
    • Boggiatto, P.M., Jie, F., Ghosh, M., Gibson-Corley, K.N., Ramer-Tait, A.E. et al. (2009) Altered dendritic cell phenotype in response to Leishmania amazonensis amastigote infection is mediated by MAP kinase. ERK. Am. J. Pathol., 174, 1818-1826.
    • (2009) ERK. Am. J. Pathol. , vol.174 , pp. 1818-1826
    • Boggiatto, P.M.1    Jie, F.2    Ghosh, M.3    Gibson-Corley, K.N.4    Ramer-Tait, A.E.5
  • 110
    • 44749087522 scopus 로고    scopus 로고
    • Downregulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes
    • Xin, L., Li, K., and Soong, L. (2008) Downregulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes. Mol. Immunol., 45, 3371-3382.
    • (2008) Mol. Immunol. , vol.45 , pp. 3371-3382
    • Xin, L.1    Li, K.2    Soong, L.3
  • 111
    • 42949160142 scopus 로고    scopus 로고
    • Leishmania major infection activates NF-kappaB and interferon regulatory factors 1 and 8 in human dendritic cells
    • Jayakumar, A., Donovan, M.J., Tripathi, V., Ramalho-Ortigao, M., and McDowell, M. A. (2008) Leishmania major infection activates NF-kappaB and interferon regulatory factors 1 and 8 in human dendritic cells. Infect. Immun., 76, 2138-2148.
    • (2008) Infect. Immun. , vol.76 , pp. 2138-2148
    • Jayakumar, A.1    Donovan, M.J.2    Tripathi, V.3    Ramalho-Ortigao, M.4    McDowell, M.A.5
  • 112
    • 0036707521 scopus 로고    scopus 로고
    • PI3K-mediated negative feedback regulation of IL-12 production in DCs
    • Fukao, T., Tanabe, M., Terauchi, Y., Ota, T., Matsuda, S. et al. (2002) PI3K-mediated negative feedback regulation of IL-12 production in DCs. Nat. Immunol., 3, 875-881.
    • (2002) Nat. Immunol. , vol.3 , pp. 875-881
    • Fukao, T.1    Tanabe, M.2    Terauchi, Y.3    Ota, T.4    Matsuda, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.