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Volumn 6, Issue 4, 2010, Pages 1-16

Keratinocytes determine Th1 immunity during early experimental leishmaniasis

Author keywords

[No Author keywords available]

Indexed keywords

CALGRANULIN A; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; OSTEOPONTIN;

EID: 77954037796     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000871     Document Type: Article
Times cited : (56)

References (65)
  • 1
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • Sacks D, Noben-Trauth N (2002) The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol 2: 845-858.
    • (2002) Nat Rev Immunol , vol.2 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 2
    • 0027431908 scopus 로고
    • Resistance of mice to experimental leishmaniasis is associated with more rapid appearance of mature macrophages in vitro and in vivo
    • Sunderkotter C, Kunz M, Steinbrink K, Meinardus-Hager G, Goebeler M, et al. (1993) Resistance of mice to experimental leishmaniasis is associated with more rapid appearance of mature macrophages in vitro and in vivo. J Immunol 151: 4891-4901.
    • (1993) J Immunol , vol.151 , pp. 4891-4901
    • Sunderkotter, C.1    Kunz, M.2    Steinbrink, K.3    Meinardus-Hager, G.4    Goebeler, M.5
  • 3
    • 0034283949 scopus 로고    scopus 로고
    • An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major
    • Tacchini-Cottier F, Zweifel C, Belkaid Y, Mukankundiye C, Vasei M, et al. (2000) An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major. J Immunol 165: 2628-2636.
    • (2000) J Immunol , vol.165 , pp. 2628-2636
    • Tacchini-Cottier, F.1    Zweifel, C.2    Belkaid, Y.3    Mukankundiye, C.4    Vasei, M.5
  • 4
    • 0029557947 scopus 로고
    • The influence of the site of parasite inoculation on the development of Th1 and Th2 type immune responses in (BALB/c6C57BL/6) F1 mice infected with Leishmania major
    • Nabors GS, Nolan T, Croop W, Li J, Farrell JP (1995) The influence of the site of parasite inoculation on the development of Th1 and Th2 type immune responses in (BALB/c6C57BL/6) F1 mice infected with Leishmania major. Parasite Immunol 17: 569-579.
    • (1995) Parasite Immunol , vol.17 , pp. 569-579
    • Nabors, G.S.1    Nolan, T.2    Croop, W.3    Li, J.4    Farrell, J.P.5
  • 5
    • 0036853910 scopus 로고    scopus 로고
    • Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ
    • Constant SL, Brogdon JL, Piggott DA, Herrick CA, Visintin I, et al. (2002) Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ. J Clin Invest 110: 1441-1448.
    • (2002) J Clin Invest , vol.110 , pp. 1441-1448
    • Constant, S.L.1    Brogdon, J.L.2    Piggott, D.A.3    Herrick, C.A.4    Visintin, I.5
  • 6
    • 0348135024 scopus 로고    scopus 로고
    • Dendritic-cell control of pathogen-driven T-cell polarization
    • Kapsenberg ML (2003) Dendritic-cell control of pathogen-driven T-cell polarization. Nat Rev Immunol 3: 984-993.
    • (2003) Nat Rev Immunol , vol.3 , pp. 984-993
    • Kapsenberg, M.L.1
  • 7
    • 0036293726 scopus 로고    scopus 로고
    • An innate sense of danger
    • Matzinger P (2002) An innate sense of danger. Ann N Y Acad Sci 961: 341-342.
    • (2002) Ann N Y Acad Sci , vol.961 , pp. 341-342
    • Matzinger, P.1
  • 8
    • 33846990935 scopus 로고    scopus 로고
    • Friendly and dangerous signals: Is the tissue in control?
    • Matzinger P (2007) Friendly and dangerous signals: is the tissue in control? Nat Immunol 8: 11-13.
    • (2007) Nat Immunol , vol.8 , pp. 11-13
    • Matzinger, P.1
  • 9
    • 0041488744 scopus 로고    scopus 로고
    • Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice
    • Von Stebut E, Ehrchen JM, Belkaid Y, Kostka SL, Molle K, et al. (2003) Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice. J Exp Med 198: 191-199.
    • (2003) J Exp Med , vol.198 , pp. 191-199
    • von Stebut, E.1    Ehrchen, J.M.2    Belkaid, Y.3    Kostka, S.L.4    Molle, K.5
  • 10
  • 11
    • 0036578644 scopus 로고    scopus 로고
    • GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways
    • Dahlquist KD, Salomonis N, Vranizan K, Lawlor SC, Conklin BR (2002) GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat Genet 31: 19-20.
    • (2002) Nat Genet , vol.31 , pp. 19-20
    • Dahlquist, K.D.1    Salomonis, N.2    Vranizan, K.3    Lawlor, S.C.4    Conklin, B.R.5
  • 12
    • 0037263812 scopus 로고    scopus 로고
    • MAPPFinder: Using Gene Ontology and GenMAPP to create a global geneexpression profile from microarray data
    • Doniger SW, Salomonis N, Dahlquist KD, Vranizan K, Lawlor SC, et al. (2003) MAPPFinder: using Gene Ontology and GenMAPP to create a global geneexpression profile from microarray data. Genome Biol 4: R7.
    • (2003) Genome Biol , vol.4
    • Doniger, S.W.1    Salomonis, N.2    Dahlquist, K.D.3    Vranizan, K.4    Lawlor, S.C.5
  • 13
    • 0035172957 scopus 로고    scopus 로고
    • IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice
    • Biedermann T, Zimmermann S, Himmelrich H, Gumy A, Egeter O, et al. (2001) IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice. Nat Immunol 2: 1054-1060.
    • (2001) Nat Immunol , vol.2 , pp. 1054-1060
    • Biedermann, T.1    Zimmermann, S.2    Himmelrich, H.3    Gumy, A.4    Egeter, O.5
  • 14
    • 0034502224 scopus 로고    scopus 로고
    • Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1
    • Diehl S, Anguita J, Hoffmeyer A, Zapton T, Ihle JN, et al. (2000) Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1. Immunity 13: 805-815.
    • (2000) Immunity , vol.13 , pp. 805-815
    • Diehl, S.1    Anguita, J.2    Hoffmeyer, A.3    Zapton, T.4    Ihle, J.N.5
  • 15
    • 0031058726 scopus 로고    scopus 로고
    • Interleukin (IL)- 6 directs the differentiation of IL-4-producing CD4+ T cells
    • Rincon M, Anguita J, Nakamura T, Fikrig E, Flavell RA (1997) Interleukin (IL)- 6 directs the differentiation of IL-4-producing CD4+ T cells. J Exp Med 185: 461-469.
    • (1997) J Exp Med , vol.185 , pp. 461-469
    • Rincon, M.1    Anguita, J.2    Nakamura, T.3    Fikrig, E.4    Flavell, R.A.5
  • 16
    • 0030734571 scopus 로고    scopus 로고
    • Lethal tuberculosis in interleukin-6-deficient mutant mice
    • Ladel CH, Blum C, Dreher A, Reifenberg K, Kopf M, et al. (1997) Lethal tuberculosis in interleukin-6-deficient mutant mice. Infect Immun 65: 4843-4849.
    • (1997) Infect Immun , vol.65 , pp. 4843-4849
    • Ladel, C.H.1    Blum, C.2    Dreher, A.3    Reifenberg, K.4    Kopf, M.5
  • 17
    • 0034193039 scopus 로고    scopus 로고
    • IL-6 is required for the development of Th1 cell-mediated murine colitis
    • Yamamoto M, Yoshizaki K, Kishimoto T, Ito H (2000) IL-6 is required for the development of Th1 cell-mediated murine colitis. J Immunol 164: 4878-4882.
    • (2000) J Immunol , vol.164 , pp. 4878-4882
    • Yamamoto, M.1    Yoshizaki, K.2    Kishimoto, T.3    Ito, H.4
  • 21
    • 0029076809 scopus 로고
    • Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice
    • Heinzel FP, Rerko RM, Ahmed F, Pearlman E (1995) Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice. J Immunol 155: 730-739.
    • (1995) J Immunol , vol.155 , pp. 730-739
    • Heinzel, F.P.1    Rerko, R.M.2    Ahmed, F.3    Pearlman, E.4
  • 22
    • 33947166288 scopus 로고    scopus 로고
    • Cutaneous Leishmania infection: Progress in pathogenesis research and experimental therapy
    • von Stebut E (2007) Cutaneous Leishmania infection: progress in pathogenesis research and experimental therapy. Exp Dermatol 16: 340-346.
    • (2007) Exp Dermatol , vol.16 , pp. 340-346
    • von Stebut, E.1
  • 23
    • 0037220342 scopus 로고    scopus 로고
    • Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1alpha/beta released from neutrophils recruited by mast cell-derived TNFalpha
    • von Stebut E, Metz M, Milon G, Knop J, Maurer M (2003) Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1alpha/beta released from neutrophils recruited by mast cell-derived TNFalpha. Blood 101: 210-215.
    • (2003) Blood , vol.101 , pp. 210-215
    • von Stebut, E.1    Metz, M.2    Milon, G.3    Knop, J.4    Maurer, M.5
  • 24
    • 0035162781 scopus 로고    scopus 로고
    • Chemokines, natural killer cells and granulocytes in the early course of Leishmania major infection in mice
    • Muller K, van ZG, Hansen B, Laufs H, Jahnke N, Solbach W, Laskay T (2001) Chemokines, natural killer cells and granulocytes in the early course of Leishmania major infection in mice. Med Microbiol Immunol 190: 73-76.
    • (2001) Med Microbiol Immunol , vol.190 , pp. 73-76
    • Muller, K.1    van, Z.G.2    Hansen, B.3    Laufs, H.4    Jahnke, N.5    Solbach, W.6    Laskay, T.7
  • 25
    • 0344327067 scopus 로고    scopus 로고
    • Early gene expression of NK cell-activating chemokines in mice resistant to Leishmania major
    • Vester B, Muller K, Solbach W, Laskay T (1999) Early gene expression of NK cell-activating chemokines in mice resistant to Leishmania major. Infect Immun 67: 3155-3159.
    • (1999) Infect Immun , vol.67 , pp. 3155-3159
    • Vester, B.1    Muller, K.2    Solbach, W.3    Laskay, T.4
  • 26
    • 0036498872 scopus 로고    scopus 로고
    • Leishmania-induced cellular recruitment during the early inflammatory response: Modulation of proinflammatory mediators
    • Matte C, Olivier M (2002) Leishmania-induced cellular recruitment during the early inflammatory response: modulation of proinflammatory mediators. J Infect Dis 185: 673-681.
    • (2002) J Infect Dis , vol.185 , pp. 673-681
    • Matte, C.1    Olivier, M.2
  • 27
    • 4544342028 scopus 로고    scopus 로고
    • Chemokine gene expression in toll-like receptor-competent and - deficient mice infected with Leishmania major
    • Antoniazi S, Price HP, Kropf P, Freudenberg MA, Galanos C, Smith DF, Muller I (2004) Chemokine gene expression in toll-like receptor-competent and - deficient mice infected with Leishmania major. Infect Immun 72: 5168-5174.
    • (2004) Infect Immun , vol.72 , pp. 5168-5174
    • Antoniazi, S.1    Price, H.P.2    Kropf, P.3    Freudenberg, M.A.4    Galanos, C.5    Smith, D.F.6    Muller, I.7
  • 28
    • 38849115240 scopus 로고    scopus 로고
    • Pathogen-imposed skewing of mouse chemokine and cytokine expression at the infected tissue site
    • Katzman SD, Fowell DJ (2008) Pathogen-imposed skewing of mouse chemokine and cytokine expression at the infected tissue site. J Clin Invest 118: 801-811.
    • (2008) J Clin Invest , vol.118 , pp. 801-811
    • Katzman, S.D.1    Fowell, D.J.2
  • 29
    • 0012478747 scopus 로고    scopus 로고
    • Leishmania major induces differential expression of costimulatory molecules on mouse epidermal cells
    • Mbow ML, DeKrey GK, Titus RG (2001) Leishmania major induces differential expression of costimulatory molecules on mouse epidermal cells. Eur J Immunol 31: 1400-1409.
    • (2001) Eur J Immunol , vol.31 , pp. 1400-1409
    • Mbow, M.L.1    Dekrey, G.K.2    Titus, R.G.3
  • 30
    • 0027473217 scopus 로고
    • Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major
    • Blank C, Fuchs H, Rappersberger K, Rollinghoff M, Moll H (1993) Parasitism of epidermal Langerhans cells in experimental cutaneous leishmaniasis with Leishmania major. J Infect Dis 167: 418-425.
    • (1993) J Infect Dis , vol.167 , pp. 418-425
    • Blank, C.1    Fuchs, H.2    Rappersberger, K.3    Rollinghoff, M.4    Moll, H.5
  • 31
    • 0028949382 scopus 로고
    • Dendritic cells in Leishmania majorimmune mice harbor persistent parasites and mediate an antigen-specific T cell immune response
    • Moll H, Flohe S, Rollinghoff M (1995) Dendritic cells in Leishmania majorimmune mice harbor persistent parasites and mediate an antigen-specific T cell immune response. Eur J Immunol 25: 693-699.
    • (1995) Eur J Immunol , vol.25 , pp. 693-699
    • Moll, H.1    Flohe, S.2    Rollinghoff, M.3
  • 32
    • 0026539390 scopus 로고
    • Murine epidermal Langerhans cells are potent stimulators of an antigen-specific T cell response to Leishmania major, the cause of cutaneous leishmaniasis
    • Will A, Blank C, Rollinghoff M, Moll H (1992) Murine epidermal Langerhans cells are potent stimulators of an antigen-specific T cell response to Leishmania major, the cause of cutaneous leishmaniasis. Eur J Immunol 22: 1341-1347.
    • (1992) Eur J Immunol , vol.22 , pp. 1341-1347
    • Will, A.1    Blank, C.2    Rollinghoff, M.3    Moll, H.4
  • 33
    • 0038342438 scopus 로고    scopus 로고
    • Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites
    • Chaussabel D, Semnani RT, McDowell MA, Sacks D, Sher A, Nutman TB (2003) Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites. Blood 102: 672-681.
    • (2003) Blood , vol.102 , pp. 672-681
    • Chaussabel, D.1    Semnani, R.T.2    McDowell, M.A.3    Sacks, D.4    Sher, A.5    Nutman, T.B.6
  • 34
    • 0031105071 scopus 로고    scopus 로고
    • Leishmania major: Promastigotes induce expression of a subset of chemokine genes in murine macrophages
    • Racoosin EL, Beverley SM (1997) Leishmania major: promastigotes induce expression of a subset of chemokine genes in murine macrophages. Exp Parasitol 85: 283-295.
    • (1997) Exp Parasitol , vol.85 , pp. 283-295
    • Racoosin, E.L.1    Beverley, S.M.2
  • 35
    • 0029978144 scopus 로고    scopus 로고
    • Leishmania major: Infection of human monocytes induces expression of IL-8 and MCAF
    • Badolato R, Sacks DL, Savoia D, Musso T (1996) Leishmania major: infection of human monocytes induces expression of IL-8 and MCAF. Exp Parasitol 82: 21-26.
    • (1996) Exp Parasitol , vol.82 , pp. 21-26
    • Badolato, R.1    Sacks, D.L.2    Savoia, D.3    Musso, T.4
  • 36
    • 0024463091 scopus 로고
    • Enhancement of macrophage IL-1 production by Leishmania major infection in vitro and its inhibition by IFN-gamma
    • Cillari E, Dieli M, Maltese E, Milano S, Salerno A, Liew FY (1989) Enhancement of macrophage IL-1 production by Leishmania major infection in vitro and its inhibition by IFN-gamma. J Immunol 143: 2001-2005.
    • (1989) J Immunol , vol.143 , pp. 2001-2005
    • Cillari, E.1    Dieli, M.2    Maltese, E.3    Milano, S.4    Salerno, A.5    Liew, F.Y.6
  • 38
    • 0036073210 scopus 로고    scopus 로고
    • Leishmania promastigotes release a granulocyte chemotactic factor and induce interleukin-8 release but inhibit gamma interferon-inducible protein 10 production by neutrophil granulocytes
    • van Zandbergen G, Hermann N, Laufs H, Solbach W, Laskay T (2002) Leishmania promastigotes release a granulocyte chemotactic factor and induce interleukin-8 release but inhibit gamma interferon-inducible protein 10 production by neutrophil granulocytes. Infect Immun 70: 4177-4184.
    • (2002) Infect Immun , vol.70 , pp. 4177-4184
    • van Zandbergen, G.1    Hermann, N.2    Laufs, H.3    Solbach, W.4    Laskay, T.5
  • 41
    • 23044431647 scopus 로고    scopus 로고
    • Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype
    • Renkl AC, Wussler J, Ahrens T, Thoma K, Kon S, Uede T, Martin SF, Simon JC, Weiss JM (2005) Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype. Blood 106: 946-955.
    • (2005) Blood , vol.106 , pp. 946-955
    • Renkl, A.C.1    Wussler, J.2    Ahrens, T.3    Thoma, K.4    Kon, S.5    Uede, T.6    Martin, S.F.7    Simon, J.C.8    Weiss, J.M.9
  • 42
    • 0042991289 scopus 로고    scopus 로고
    • CD4+ T cell polarization in mice is modulated by strain-specific major histocompatibility complex-independent differences within dendritic cells
    • Filippi C, Hugues S, Cazareth J, Julia V, Glaichenhaus N, Ugolini S (2003) CD4+ T cell polarization in mice is modulated by strain-specific major histocompatibility complex-independent differences within dendritic cells. J Exp Med 198: 201-209.
    • (2003) J Exp Med , vol.198 , pp. 201-209
    • Filippi, C.1    Hugues, S.2    Cazareth, J.3    Julia, V.4    Glaichenhaus, N.5    Ugolini, S.6
  • 43
    • 0029584457 scopus 로고
    • In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-
    • Launois P, Ohteki T, Swihart K, MacDonald HR, Louis JA (1995) In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-. Eur J Immunol 25: 3298-3307.
    • (1995) Eur J Immunol , vol.25 , pp. 3298-3307
    • Launois, P.1    Ohteki, T.2    Swihart, K.3    Macdonald, H.R.4    Louis, J.A.5
  • 45
    • 0034193027 scopus 로고    scopus 로고
    • In BALB/c mice, IL-4 productionduring the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease
    • Himmelrich H, Launois P, Maillard I, Biedermann T, Tacchini-Cottier F, Locksley RM, Rocken M, Louis JA (2000) In BALB/c mice, IL-4 productionduring the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease. J Immunol 164: 4819-4825.
    • (2000) J Immunol , vol.164 , pp. 4819-4825
    • Himmelrich, H.1    Launois, P.2    Maillard, I.3    Biedermann, T.4    Tacchini-Cottier, F.5    Locksley, R.M.6    Rocken, M.7    Louis, J.A.8
  • 46
    • 0033802387 scopus 로고    scopus 로고
    • Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells
    • Hochrein H, O'Keeffe M, Luft T, Vandenabeele S, Grumont RJ, Maraskovsky E, Shortman K (2000) Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells. J Exp Med 192: 823-833.
    • (2000) J Exp Med , vol.192 , pp. 823-833
    • Hochrein, H.1    O'Keeffe, M.2    Luft, T.3    Vandenabeele, S.4    Grumont, R.J.5    Maraskovsky, E.6    Shortman, K.7
  • 49
    • 46149084901 scopus 로고    scopus 로고
    • Modulation of dendritic cell differentiation by HLA-G and ILT4 requires the IL-6-STAT3 signaling pathway
    • Liang S, Ristich V, Arase H, Dausset J, Carosella ED, Horuzsko A (2008) Modulation of dendritic cell differentiation by HLA-G and ILT4 requires the IL-6-STAT3 signaling pathway. Proc Natl Acad Sci U S A 105: 8357-8362.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8357-8362
    • Liang, S.1    Ristich, V.2    Arase, H.3    Dausset, J.4    Carosella, E.D.5    Horuzsko, A.6
  • 50
    • 27744449724 scopus 로고    scopus 로고
    • IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells
    • Kitamura H, Kamon H, Sawa S, Park SJ, Katunuma N, Ishihara K, Murakami M, Hirano T (2005) IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells. Immunity 23: 491-502.
    • (2005) Immunity , vol.23 , pp. 491-502
    • Kitamura, H.1    Kamon, H.2    Sawa, S.3    Park, S.J.4    Katunuma, N.5    Ishihara, K.6    Murakami, M.7    Hirano, T.8
  • 51
    • 0034577943 scopus 로고    scopus 로고
    • IL-6 switches the differentiation of monocytes from dendritic cells to macrophages
    • Chomarat P, Banchereau J, Davoust J, Palucka AK (2000) IL-6 switches the differentiation of monocytes from dendritic cells to macrophages. Nat Immunol 1: 510-514.
    • (2000) Nat Immunol , vol.1 , pp. 510-514
    • Chomarat, P.1    Banchereau, J.2    Davoust, J.3    Palucka, A.K.4
  • 53
    • 0030955851 scopus 로고    scopus 로고
    • Efficient immunity against Leishmania major in the absence of interleukin-6
    • Moskowitz NH, Brown DR, Reiner SL (1997) Efficient immunity against Leishmania major in the absence of interleukin-6. Infect Immun 65: 2448-2450.
    • (1997) Infect Immun , vol.65 , pp. 2448-2450
    • Moskowitz, N.H.1    Brown, D.R.2    Reiner, S.L.3
  • 54
    • 0034924514 scopus 로고    scopus 로고
    • Interleukin-6 deficiency influences cytokine expression in susceptible BALB mice infected with Leishmania major but does not alter the outcome of disease
    • Titus RG, DeKrey GK, Morris RV, Soares MB (2001) Interleukin-6 deficiency influences cytokine expression in susceptible BALB mice infected with Leishmania major but does not alter the outcome of disease. Infect Immun 69: 5189-5192.
    • (2001) Infect Immun , vol.69 , pp. 5189-5192
    • Titus, R.G.1    Dekrey, G.K.2    Morris, R.V.3    Soares, M.B.4
  • 55
    • 33847163271 scopus 로고    scopus 로고
    • CD4(+)CD25(2) Foxp3(2) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis
    • Anderson CF, Oukka M, Kuchroo VJ, Sacks D (2007) CD4(+)CD25(2) Foxp3(2) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J Exp Med %19;204: 285-297.
    • (2007) J Exp Med %19 , vol.204 , pp. 285-297
    • Anderson, C.F.1    Oukka, M.2    Kuchroo, V.J.3    Sacks, D.4
  • 56
    • 33645077332 scopus 로고    scopus 로고
    • Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens
    • Suffia IJ, Reckling SK, Piccirillo CA, Goldszmid RS, Belkaid Y (2006) Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens. J Exp Med %20;203: 777-788.
    • (2006) J Exp Med %20 , vol.203 , pp. 777-788
    • Suffia, I.J.1    Reckling, S.K.2    Piccirillo, C.A.3    Goldszmid, R.S.4    Belkaid, Y.5
  • 57
    • 0041334172 scopus 로고    scopus 로고
    • The role of CD4(+)CD25(+) regulatory T cells in Leishmania infection
    • Belkaid Y (2003) The role of CD4(+)CD25(+) regulatory T cells in Leishmania infection. Expert Opin Biol Ther 3: 875-885.
    • (2003) Expert Opin Biol Ther , vol.3 , pp. 875-885
    • Belkaid, Y.1
  • 58
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
    • Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL (2002) CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 420: 502-507.
    • (2002) Nature , vol.420 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 59
    • 0037105473 scopus 로고    scopus 로고
    • The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells
    • Aseffa A, Gumy A, Launois P, MacDonald HR, Louis JA, Tacchini-Cottier F (2002) The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells. J Immunol 169: 3232-3241.
    • (2002) J Immunol , vol.169 , pp. 3232-3241
    • Aseffa, A.1    Gumy, A.2    Launois, P.3    Macdonald, H.R.4    Louis, J.A.5    Tacchini-Cottier, F.6
  • 61
    • 33847368263 scopus 로고    scopus 로고
    • The contact allergen nickel triggers a unique inflammatory and proangiogenic gene expression pattern via activation of NF-kappaB and hypoxia-inducible factor-1alpha
    • Viemann D, Schmidt M, Tenbrock K, Schmid S, Muller V, Klimmek K, Ludwig S, Roth J, Goebeler M (2007) The contact allergen nickel triggers a unique inflammatory and proangiogenic gene expression pattern via activation of NF-kappaB and hypoxia-inducible factor-1alpha. J Immunol 178: 3198-3207.
    • (2007) J Immunol , vol.178 , pp. 3198-3207
    • Viemann, D.1    Schmidt, M.2    Tenbrock, K.3    Schmid, S.4    Muller, V.5    Klimmek, K.6    Ludwig, S.7    Roth, J.8    Goebeler, M.9
  • 62
    • 0035073259 scopus 로고    scopus 로고
    • Expression and regulation of osteopontin and connective tissue growth factor transcripts in rat anterior pituitary
    • Ehrchen J, Heuer H, Sigmund R, Schafer MK, Bauer K (2001) Expression and regulation of osteopontin and connective tissue growth factor transcripts in rat anterior pituitary. J Endocrinol 169: 87-96.
    • (2001) J Endocrinol , vol.169 , pp. 87-96
    • Ehrchen, J.1    Heuer, H.2    Sigmund, R.3    Schafer, M.K.4    Bauer, K.5


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