Leishmania-induced inactivation of the macrophage transcription Factor AP-1 Is Mediated by the Parasite Metalloprotease GP63

PLoS Pathogens

Volumn 6, Issue 10, 2010, Pages

  Contreras, Irazú ^a,b   Gómez, María Adelaida ^a,b   Nguyen, Oliver ^a   Shio, Marina T ^a,b   McMaster, Robert W ^c   Olivier, Martin ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHALASIN D; GP63 PROTEIN; METHYL BETA CYCLODEXTRIN; PROTEIN C JUN; PROTOZOAL PROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; GLYCOPROTEIN GP63, LEISHMANIA; METALLOPROTEINASE;

ANIMAL CELL; ARTICLE; DOWN REGULATION; ENZYME ACTIVITY; HOST CELL; IMMUNOPRECIPITATION; LEISHMANIA MEXICANA; LEISHMANIASIS; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PHAGOCYTOSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; IMMUNE EVASION; IMMUNOLOGY; LEISHMANIA; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN BINDING; PROTEIN PROCESSING; TRANSGENIC ORGANISM;

LEISHMANIA MEXICANA;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; DOWN-REGULATION; GENE EXPRESSION REGULATION; IMMUNE EVASION; LEISHMANIA; MACROPHAGES; METALLOENDOPEPTIDASES; METALLOPROTEASES; MICE; MOLECULAR SEQUENCE DATA; ORGANISMS, GENETICALLY MODIFIED; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRANSCRIPTION FACTOR AP-1;

EID: 78449240895     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001148     Document Type: Article

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