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Volumn 88, Issue 1, 2010, Pages 9-20

MAPK-directed phosphatases preferentially regulate pro- and anti-inflammatory cytokines in experimental visceral leishmaniasis: Involvement of distinct protein kinase C isoforms

Author keywords

Inducible NO synthase; Macrophage; Protein phosphatase 2A

Indexed keywords

CYSTATIN; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE C; TUMOR NECROSIS FACTOR ALPHA; DUAL SPECIFICITY PHOSPHATASE 6; DUSP1 PROTEIN, MOUSE; DUSP6 PROTEIN, MOUSE; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2;

EID: 77954686146     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0909644     Document Type: Article
Times cited : (57)

References (32)
  • 1
    • 33644976705 scopus 로고    scopus 로고
    • MAP kinases in immune responses
    • Zhang, Y. L., Dong, C. (2005) MAP kinases in immune responses. Cell. Mol. Immunol. 2, 20-27.
    • (2005) Cell. Mol. Immunol. , vol.2 , pp. 20-27
    • Zhang, Y.L.1    Dong, C.2
  • 2
    • 34547156710 scopus 로고    scopus 로고
    • Regulation of MAP kinases by MAP kinase phosphatases
    • Kondoh, K., Nishida, E. (2006) Regulation of MAP kinases by MAP kinase phosphatases. Biochim. Biophys. Acta 1773, 1227-1237.
    • (2006) Biochim. Biophys. Acta , vol.1773 , pp. 1227-1237
    • Kondoh, K.1    Nishida, E.2
  • 3
    • 17444420714 scopus 로고    scopus 로고
    • Subversion mechanisms by which Leishmania parasites can escape the host immune response: A signaling point of view
    • DOI 10.1128/CMR.18.2.293-305.2005
    • Olivier, M., Gregory, D. J., Forget, G. (2005) Subversion mechanisms by which Leishmania parasites can escape the host immune response: a signaling point of view. Clin. Microbiol. Rev. 18, 293-305. (Pubitemid 40548295)
    • (2005) Clinical Microbiology Reviews , vol.18 , Issue.2 , pp. 293-305
    • Olivier, M.1    Gregory, D.J.2    Forget, G.3
  • 4
    • 0032782792 scopus 로고    scopus 로고
    • Altered tyrosine phosphorylation of ERK1 MAP kinase and other macrophage molecules caused by Leishmania amastigotes
    • DOI 10.1016/S0166-6851(99)00067-5, PII S0166685199000675
    • Martiny, A., Meyer-Fernandes, J. R., de Souza, W., Vannier-Santos, M. A. (1999) Altered tyrosine phosphorylation of ERK1 MAP kinase and other macrophage molecules caused by Leishmania amastigotes. Mol. Biochem. Parasitol. 102, 1-12. (Pubitemid 29342269)
    • (1999) Molecular and Biochemical Parasitology , vol.102 , Issue.1 , pp. 1-12
    • Martiny, A.1    Meyer-Fernandes, J.R.2    De Souza, W.3    Vannier-Santos, M.A.4
  • 5
    • 0036893697 scopus 로고    scopus 로고
    • Leishmania donovani suppresses activated protein 1 and NF-κB activation in host macrophages via ceramide generation: Involvement of extracellular signal-regulated kinase
    • Ghosh, S., Bhattacharya, S., Sirkar, M., Sa, G. S., Das, T., Majumder, D., Roy, S., Majumder, S. (2002) Leishmania donovani suppresses activated protein 1 and NF-κB activation in host macrophages via ceramide generation: involvement of extracellular signal-regulated kinase. Infect. Immun. 70, 6828-6838.
    • (2002) Infect. Immun. , vol.70 , pp. 6828-6838
    • Ghosh, S.1    Bhattacharya, S.2    Sirkar, M.3    Sa, G.S.4    Das, T.5    Majumder, D.6    Roy, S.7    Majumder, S.8
  • 6
    • 0037460059 scopus 로고    scopus 로고
    • CD40 signaling is impaired in L. major-infected macrophages and is rescued by a p38MAPK activator establishing a host-protective memory T cell response
    • Awasthi, A., Mathur, R., Khan, A., Joshi, B. N., Jain, N., Sawant, S., Boppana, R., Mitra, D., Saha, B. (2003) CD40 signaling is impaired in L. major-infected macrophages and is rescued by a p38MAPK activator establishing a host-protective memory T cell response. J. Exp. Med. 197, 1037-1043.
    • (2003) J. Exp. Med. , vol.197 , pp. 1037-1043
    • Awasthi, A.1    Mathur, R.2    Khan, A.3    Joshi, B.N.4    Jain, N.5    Sawant, S.6    Boppana, R.7    Mitra, D.8    Saha, B.9
  • 7
    • 33750468333 scopus 로고    scopus 로고
    • Role of host protein tyrosine phosphatase SHP-1 in Leishmania donovani-induced inhibition of nitric oxide production
    • Forget, G., Gregory, D. J., Whitcombe, L. A., Olivier, M. (2006) Role of host protein tyrosine phosphatase SHP-1 in Leishmania donovani-induced inhibition of nitric oxide production. Infect. Immun. 74, 6272-6279.
    • (2006) Infect. Immun. , vol.74 , pp. 6272-6279
    • Forget, G.1    Gregory, D.J.2    Whitcombe, L.A.3    Olivier, M.4
  • 8
    • 0030794511 scopus 로고    scopus 로고
    • Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells
    • Franklin, C. C., Kraft, A. S. (1997) Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells. J. Biol. Chem. 272, 16917-16923.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16917-16923
    • Franklin, C.C.1    Kraft, A.S.2
  • 9
    • 31344475056 scopus 로고    scopus 로고
    • Dual specificity phosphatase 1 (DUSP 1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock
    • Hammer, M., Mages, J., Dietrich, H., Servatius, A., Howells, N., Cato, A. C., Lang, R. (2006) Dual specificity phosphatase 1 (DUSP 1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock. J. Exp. Med. 203, 15-20.
    • (2006) J. Exp. Med. , vol.203 , pp. 15-20
    • Hammer, M.1    Mages, J.2    Dietrich, H.3    Servatius, A.4    Howells, N.5    Cato, A.C.6    Lang, R.7
  • 11
    • 0030049063 scopus 로고    scopus 로고
    • A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation
    • Mourey, R. J., Vega, Q. C., Campbell, J. S., Wenderoth, M. P., Hauschka, S. D., Krebs, E. G., Dixon, J. E. (1996) A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation. J. Biol. Chem. 271, 3795-3802.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3795-3802
    • Mourey, R.J.1    Vega, Q.C.2    Campbell, J.S.3    Wenderoth, M.P.4    Hauschka, S.D.5    Krebs, E.G.6    Dixon, J.E.7
  • 12
    • 0029910140 scopus 로고    scopus 로고
    • The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen activated protein kinases
    • Muda, M., Theodosiou, A., Rodrigues, N., Boschert, U., Camps, M., Gillieron, C., Davies, K., Ashworth, A., Arkinstall, S. (1996) The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen activated protein kinases. J. Biol. Chem. 271, 27205-27208.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27205-27208
    • Muda, M.1    Theodosiou, A.2    Rodrigues, N.3    Boschert, U.4    Camps, M.5    Gillieron, C.6    Davies, K.7    Ashworth, A.8    Arkinstall, S.9
  • 13
    • 22544466156 scopus 로고    scopus 로고
    • Macrophages survive hyperoxia via prolonged ERK activation due to phosphatase down-regulation
    • Nyunoya, T., Monick, M. M., Powers, L. S., Yarovinsky, T. O., Hunninghake, G. W. (2005) Macrophages survive hyperoxia via prolonged ERK activation due to phosphatase down-regulation. J. Biol. Chem. 280, 26295-26302.
    • (2005) J. Biol. Chem. , vol.280 , pp. 26295-26302
    • Nyunoya, T.1    Monick, M.M.2    Powers, L.S.3    Yarovinsky, T.O.4    Hunninghake, G.W.5
  • 14
    • 0027143725 scopus 로고
    • Protein serine/threonine phosphatases: Structure, regulation and functions in cell growth
    • Mumby, M. C., Walter, G. (1993) Protein serine/threonine phosphatases: structure, regulation and functions in cell growth. Physiol. Rev. 73, 673-700.
    • (1993) Physiol. Rev. , vol.73 , pp. 673-700
    • Mumby, M.C.1    Walter, G.2
  • 15
    • 11144339324 scopus 로고    scopus 로고
    • Differential activation of the transcription factor cyclic AMP response element binding protein (CREB) in macrophages following infection with pathogenic and non-pathogenic Mycobacteria and role for CREB in tumor necrosis factor α production
    • Roach, S. K., Lee, S. B., Schorey, J. S. (2005) Differential activation of the transcription factor cyclic AMP response element binding protein (CREB) in macrophages following infection with pathogenic and non-pathogenic Mycobacteria and role for CREB in tumor necrosis factor α production. Infect. Immun. 73, 514-522.
    • (2005) Infect. Immun. , vol.73 , pp. 514-522
    • Roach, S.K.1    Lee, S.B.2    Schorey, J.S.3
  • 16
    • 0033961822 scopus 로고    scopus 로고
    • Protein kinase Cε is required for the induction of mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages
    • Valledor, A. F., Xaus, J., Comalada, M., Soler, C., Celada, A. (2000) Protein kinase C ε is required for the induction of mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. J. Immunol. 164, 29-37. (Pubitemid 30012968)
    • (2000) Journal of Immunology , vol.164 , Issue.1 , pp. 29-37
    • Valledor, A.F.1    Xaus, J.2    Comalada, M.3    Soler, C.4    Celada, A.5
  • 17
    • 0030769625 scopus 로고    scopus 로고
    • Protein phosphatase 2A is a critical regulator of protein kinase C ξ signaling targeted by SV40 small t to promote cell growth and NF-κB activation
    • DOI 10.1093/emboj/16.18.5662
    • Sontag, E., Sontag, J. M., Garcia, A. (1997) Protein phosphatase 2A is a critical regulator of protein kinase Cξ signaling targeted by SV40 small t to promote cell growth and NF-κB activation. EMBO J. 16, 5662-5671. (Pubitemid 27399858)
    • (1997) EMBO Journal , vol.16 , Issue.18 , pp. 5662-5671
    • Sontag, E.1    Sontag, J.-M.2    Garcia, A.3
  • 18
    • 34248402756 scopus 로고    scopus 로고
    • Leishmania donovani-induced ceramide as the key mediator of Akt dephosphorylation in murine macrophages: Role of protein kinase Cξ and phosphatase
    • DOI 10.1128/IAI.01589-06
    • Dey, R., Majumder, N., Bhattacharjee, S., Majumder, S. B., Banerjee, R., Ganguly, S., Das, P., Majumdar, S. (2007) Leishmania donovani-induced ceramide as the key mediator of Akt dephosphorylation in murine macrophages: role of protein kinase Cξ and phosphatase. Infect. Immun. 75, 2136-2142. (Pubitemid 46744299)
    • (2007) Infection and Immunity , vol.75 , Issue.5 , pp. 2136-2142
    • Dey, R.1    Majumder, N.2    Bhattacharjee, S.3    Majumdar, S.B.4    Banerjee, R.5    Ganguly, S.6    Das, P.7    Majumdar, S.8
  • 19
    • 0035869563 scopus 로고    scopus 로고
    • Successful therapy of lethal murine visceral leishmaniasis with cystatin involves up-regulation of nitric oxide and a favorable T cell response
    • Das, L., Datta, N., Bandyopathyay, S., Das, P. K. (2001) Successful therapy of lethal murine visceral leishmaniasis with cystatin involves up-regulation of nitric oxide and a favorable T cell response. J. Immunol. 166, 4020-4028. (Pubitemid 32224931)
    • (2001) Journal of Immunology , vol.166 , Issue.6 , pp. 4020-4028
    • Das, L.1    Datta, N.2    Bandyopadhyay, S.3    Das, P.K.4
  • 20
    • 0032825554 scopus 로고    scopus 로고
    • Synergistic effect of interferon-γ and mannosylated liposome- Incorporated doxorubicin in the therapy of experimental visceral leishmaniasis
    • DOI 10.1086/314929
    • Kole, L., Das, L., Das, P. K. (1999) Synergistic effect of interferon-γ and mannosylated liposome-incorporated doxorubicin in the therapy of experimental visceral leishmaniasis. J. Infect. Dis. 180, 811-820. (Pubitemid 29411368)
    • (1999) Journal of Infectious Diseases , vol.180 , Issue.3 , pp. 811-820
    • Kole, L.1    Das, L.2    Das, P.K.3
  • 21
    • 0027164877 scopus 로고
    • Role and effect of IL-2 in experimental visceral leishmaniasis
    • Murray, H. W., Miralles, G. D., Stoeckle, M. Y., McDermott, D. F. (1993) Role and effect of IL-2 in experimental visceral leishmaniasis. J. Immunol. 151, 929-938.
    • (1993) J. Immunol. , vol.151 , pp. 929-938
    • Murray, H.W.1    Miralles, G.D.2    Stoeckle, M.Y.3    McDermott, D.F.4
  • 22
    • 0020065930 scopus 로고
    • Identification and partial characterization of an extracellular acid phosphatase activity of Leishmania donovani promastigotes
    • Gottlieb, M., Dwyer, D. M. (1982) Identification and partial characterization of an extracellular acid phosphatase activity of Leishmania donovani promastigotes. Mol. Cell. Biol. 2, 76-81.
    • (1982) Mol. Cell. Biol. , vol.2 , pp. 76-81
    • Gottlieb, M.1    Dwyer, D.M.2
  • 24
    • 0033847256 scopus 로고    scopus 로고
    • Leishmania donovani promastigotes evade the activation of mitogen-activated protein kinases p38, c-Jun N-terminal kinase, and extracellular signal-regulated kinase-1/2 during infection of naïve macrophages
    • Prive, C., Descoteaux, A. (2000) Leishmania donovani promastigotes evade the activation of mitogen-activated protein kinases p38, c-Jun N-terminal kinase, and extracellular signal-regulated kinase-1/2 during infection of naïve macrophages. Eur. J. Immunol. 30, 2235-2244.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2235-2244
    • Prive, C.1    Descoteaux, A.2
  • 25
    • 10644224230 scopus 로고    scopus 로고
    • Molecular determinants of substrate recognition in hemotopoietic protein-tyrosine phosphatase
    • Huang, Z., Zhou, B., Zhang, Z. Y. (2004) Molecular determinants of substrate recognition in hemotopoietic protein-tyrosine phosphatase. J. Biol. Chem. 279, 52150-52159.
    • (2004) J. Biol. Chem. , vol.279 , pp. 52150-52159
    • Huang, Z.1    Zhou, B.2    Zhang, Z.Y.3
  • 26
    • 0037220735 scopus 로고    scopus 로고
    • NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling
    • DOI 10.1038/nn989
    • Paul, S., Nairn, A. C., Wang, P., Lombroso, P. J. (2003) NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat. Neurosci. 6, 34-42. (Pubitemid 36026330)
    • (2003) Nature Neuroscience , vol.6 , Issue.1 , pp. 34-42
    • Paul, S.1    Nairn, A.C.2    Wang, P.3    Lombroso, P.J.4
  • 27
    • 0029074550 scopus 로고
    • Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells
    • Whisler, R. L., Goyette, M. A., Grants, I. S., Newhouse, Y. G. (1995) Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells. Arch. Biochem. Biophys. 319, 23-35.
    • (1995) Arch. Biochem. Biophys. , vol.319 , pp. 23-35
    • Whisler, R.L.1    Goyette, M.A.2    Grants, I.S.3    Newhouse, Y.G.4
  • 28
    • 0036884621 scopus 로고    scopus 로고
    • Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages
    • Chen, P., Li, J., Barnes, J., Kokkonen, G. C., Lee, J. C., Yusen, L. (2002) Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. J. Immunol. 169, 6408-6416. (Pubitemid 36903490)
    • (2002) Journal of Immunology , vol.169 , Issue.11 , pp. 6408-6416
    • Chen, P.1    Li, J.2    Barnes, J.3    Kokkonen, G.C.4    Lee, J.C.5    Liu, Y.6
  • 29
    • 31144452241 scopus 로고    scopus 로고
    • Essential role of MAPK phosphatase-1 in the negative control of innate immune responses
    • Salojin, K. V., Owusu, I. B., Millerchip, K. A., Potter, M., Platt, K. A., Oravecz, T. (2006) Essential role of MAPK phosphatase-1 in the negative control of innate immune responses. J. Immunol. 176, 1899-1907. (Pubitemid 43134335)
    • (2006) Journal of Immunology , vol.176 , Issue.3 , pp. 1899-1907
    • Salojin, K.V.1    Owusu, I.B.2    Millerchip, K.A.3    Potter, M.4    Platt, K.A.5    Oravecz, T.6
  • 30
    • 14844310210 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: Attenuation of proinflammatory cytokine biosynthesis via feed back control of p38
    • Zhao, Q., Shepherd, E. G., Manson, M. E., Nelin, L. D., Sorokin, A., Liu, Y. (2005) The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feed back control of p38. J. Biol. Chem. 280, 8101-8108.
    • (2005) J. Biol. Chem. , vol.280 , pp. 8101-8108
    • Zhao, Q.1    Shepherd, E.G.2    Manson, M.E.3    Nelin, L.D.4    Sorokin, A.5    Liu, Y.6
  • 31
    • 33847788947 scopus 로고    scopus 로고
    • Role of protein tyrosine phosphatases in the regulation of interferon-γ-induced macrophage nitric oxide generation: Implication of ERK pathway and AP-1 activation
    • Blanchette, J., Pouliot, P., Olivier, M. (2007) Role of protein tyrosine phosphatases in the regulation of interferon-γ-induced macrophage nitric oxide generation: implication of ERK pathway and AP-1 activation. J. Leukoc. Biol. 81, 835-844.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 835-844
    • Blanchette, J.1    Pouliot, P.2    Olivier, M.3
  • 32
    • 76249114134 scopus 로고    scopus 로고
    • Ubiquitin conjugation of open reading frame F DNA vaccine leads to enhanced cell-mediated immune response and induces protection against both antimony-susceptible and -resistant strains of Leishmania donovani
    • Sharma, A., Madhubala, R. (2009) Ubiquitin conjugation of open reading frame F DNA vaccine leads to enhanced cell-mediated immune response and induces protection against both antimony-susceptible and -resistant strains of Leishmania donovani. J. Immunol. 183, 7719-7731.
    • (2009) J. Immunol. , vol.183 , pp. 7719-7731
    • Sharma, A.1    Madhubala, R.2


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