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Volumn 10, Issue 4, 2013, Pages 771-781

Epigenetic Regulation of Axon Outgrowth and Regeneration in CNS Injury: The First Steps Forward

Author keywords

Axonal regeneration; DNA methylation; Epigenetics; Histone modifications; Optic nerve crush; Spinal cord injury

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; E1A ASSOCIATED P300 PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 6; HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; INTERLEUKIN 6; KRUPPEL LIKE FACTOR 4; METHYL CPG BINDING PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MYELIN ASSOCIATED GLYCOPROTEIN; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEOCHONDROITIN SULFATE; RETINOIC ACID RECEPTOR BETA; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; STAT3 PROTEIN;

EID: 84886285005     PISSN: 19337213     EISSN: 18787479     Source Type: Journal    
DOI: 10.1007/s13311-013-0203-8     Document Type: Review
Times cited : (33)

References (133)
  • 1
    • 33746308062 scopus 로고    scopus 로고
    • Glial inhibition of CNS axon regeneration
    • Yiu G, He Z. Glial inhibition of CNS axon regeneration. Nat Rev Neurosci 2006;7: 617-627.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 617-627
    • Yiu, G.1    He, Z.2
  • 2
    • 75349109284 scopus 로고    scopus 로고
    • Molecular targets for axon regeneration: focus on the intrinsic pathways
    • Di Giovanni S. Molecular targets for axon regeneration: focus on the intrinsic pathways. Expert Opin Ther Targets 2009;13: 1387-1398.
    • (2009) Expert Opin Ther Targets , vol.13 , pp. 1387-1398
    • Di Giovanni, S.1
  • 3
    • 0033137077 scopus 로고    scopus 로고
    • Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury
    • Neumann S, Woolf CJ Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury. Neuron 2999;23: 83-91.
    • (2999) Neuron , vol.23 , pp. 83-91
    • Neumann, S.1    Woolf, C.J.2
  • 4
    • 33644793597 scopus 로고    scopus 로고
    • Axonal regeneration in adult CNS neurons-signaling molecules and pathways
    • Teng FY, Tang BL. Axonal regeneration in adult CNS neurons-signaling molecules and pathways. J Neurochem 2006;96: 1501-1508.
    • (2006) J Neurochem , vol.96 , pp. 1501-1508
    • Teng, F.Y.1    Tang, B.L.2
  • 5
    • 0035873174 scopus 로고    scopus 로고
    • Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A
    • Merkler D, Lindner R, Puttagunta R, Di Giovanni S. Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A. J Neurosci 2001;21: 3665-3673.
    • (2001) J Neurosci , vol.21 , pp. 3665-3673
    • Merkler, D.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 6
    • 0032703535 scopus 로고    scopus 로고
    • Influence of the axotomy to cell body distance in rat rubrospinal and spinal motoneurons: differential regulation of GAP-43, tubulins, and neurofilament-M
    • Fernandes KJ, Fan DP, Tsui BJ, Cassar SL, Tetzlaff W. Influence of the axotomy to cell body distance in rat rubrospinal and spinal motoneurons: differential regulation of GAP-43, tubulins, and neurofilament-M. J Comp Neurol 1999;414: 495-510.
    • (1999) J Comp Neurol , vol.414 , pp. 495-510
    • Fernandes, K.J.1    Fan, D.P.2    Tsui, B.J.3    Cassar, S.L.4    Tetzlaff, W.5
  • 7
    • 0030157682 scopus 로고    scopus 로고
    • The recovery of 5-HT immunoreactivity in lumbosacral spinal cord and locomotor function after thoracic hemisection
    • Saruhashi Y, Young W, Perkins R. The recovery of 5-HT immunoreactivity in lumbosacral spinal cord and locomotor function after thoracic hemisection. Exp Neurol 1996;139: 203-213.
    • (1996) Exp Neurol , vol.139 , pp. 203-213
    • Saruhashi, Y.1    Young, W.2    Perkins, R.3
  • 8
    • 4544373293 scopus 로고    scopus 로고
    • Long-term changes in the molecular composition of the glial scar and progressive increase of serotoninergic fibre sprouting after hemisection of the mouse spinal cord
    • Camand E, Morel MP, Faissner A, Sotelo C, Dusart I. Long-term changes in the molecular composition of the glial scar and progressive increase of serotoninergic fibre sprouting after hemisection of the mouse spinal cord. Eur J Neurosci 2004;20: 1161-1176.
    • (2004) Eur J Neurosci , vol.20 , pp. 1161-1176
    • Camand, E.1    Morel, M.P.2    Faissner, A.3    Sotelo, C.4    Dusart, I.5
  • 9
    • 0024535891 scopus 로고
    • Axonal transport and localization of B-50/GAP-43-like immunoreactivity in regenerating sciatic and facial nerves of the rat
    • Tetzlaff W, Zwiers H, Lederis K, Cassar L, Bisby MA. Axonal transport and localization of B-50/GAP-43-like immunoreactivity in regenerating sciatic and facial nerves of the rat. J Neurosci 1989;9: 1303-1313.
    • (1989) J Neurosci , vol.9 , pp. 1303-1313
    • Tetzlaff, W.1    Zwiers, H.2    Lederis, K.3    Cassar, L.4    Bisby, M.A.5
  • 10
  • 11
    • 0344737628 scopus 로고    scopus 로고
    • Differential gene expression profiles in embryonic, adult-injured and adult-uninjured rat spinal cords
    • Gris P, Murphy S, Jacob JE, Atkinson I, Brown A. Differential gene expression profiles in embryonic, adult-injured and adult-uninjured rat spinal cords. Mol Cell Neurosci 2003;24: 555-567.
    • (2003) Mol Cell Neurosci , vol.24 , pp. 555-567
    • Gris, P.1    Murphy, S.2    Jacob, J.E.3    Atkinson, I.4    Brown, A.5
  • 12
    • 0028608860 scopus 로고
    • Response of rubrospinal and corticospinal neurons to injury and neurotrophins
    • Tetzlaff W, Lindner R, Puttagunta R, Di Giovanni S. Response of rubrospinal and corticospinal neurons to injury and neurotrophins. Prog Brain Res 1994;103: 271-286.
    • (1994) Prog Brain Res , vol.103 , pp. 271-286
    • Tetzlaff, W.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 13
    • 31944442910 scopus 로고    scopus 로고
    • Profound differences in spontaneous long-term functional recovery after defined spinal tract lesions in the rat
    • Hendriks WT, Lindner R, Puttagunta R, Di Giovanni S. Profound differences in spontaneous long-term functional recovery after defined spinal tract lesions in the rat. J Neurotrauma 2006;23: 18-35.
    • (2006) J Neurotrauma , vol.23 , pp. 18-35
    • Hendriks, W.T.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 14
    • 0036434324 scopus 로고    scopus 로고
    • Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury
    • Jin Y, Fischer I, Tessler A, Houle JD. Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury. Exp Neurol 2002;177: 265-275.
    • (2002) Exp Neurol , vol.177 , pp. 265-275
    • Jin, Y.1    Fischer, I.2    Tessler, A.3    Houle, J.D.4
  • 15
    • 0345227300 scopus 로고    scopus 로고
    • Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration
    • Tobias CA, Lindner R, Puttagunta R, Di Giovanni S. Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration. Exp Neurol 2003;184: 97-113.
    • (2003) Exp Neurol , vol.184 , pp. 97-113
    • Tobias, C.A.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 16
    • 0026014670 scopus 로고
    • Response of facial and rubrospinal neurons to axotomy: changes in mRNA expression for cytoskeletal proteins and GAP-43
    • Tetzlaff W, Alexander SW, Miller FD, Bisby MA. Response of facial and rubrospinal neurons to axotomy: changes in mRNA expression for cytoskeletal proteins and GAP-43. J Neurosci 1991;11: 2528-2544.
    • (1991) J Neurosci , vol.11 , pp. 2528-2544
    • Tetzlaff, W.1    Alexander, S.W.2    Miller, F.D.3    Bisby, M.A.4
  • 17
    • 0024560036 scopus 로고
    • Rapid induction of the major embryonic alpha-tubulin mRNA, T alpha 1, during nerve regeneration in adult rats
    • Miller FD, Tetzlaff W, Bisby MA, Fawcett JW, Milner RJ. Rapid induction of the major embryonic alpha-tubulin mRNA, T alpha 1, during nerve regeneration in adult rats. J Neurosci 1989;9: 1452-1463.
    • (1989) J Neurosci , vol.9 , pp. 1452-1463
    • Miller, F.D.1    Tetzlaff, W.2    Bisby, M.A.3    Fawcett, J.W.4    Milner, R.J.5
  • 18
    • 4644329002 scopus 로고    scopus 로고
    • Galectin-1 expression correlates with the regenerative potential of rubrospinal and spinal motoneurons
    • McGraw J, Lindner R, Puttagunta R, Di Giovanni S. Galectin-1 expression correlates with the regenerative potential of rubrospinal and spinal motoneurons. Neuroscience 2004;128: 713-719.
    • (2004) Neuroscience , vol.128 , pp. 713-719
    • McGraw, J.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 19
    • 0027469488 scopus 로고
    • Differential expression of immediate early genes in rubrospinal neurons following axotomy in rat
    • Jenkins R, Tetzlaff W, Hunt SP. Differential expression of immediate early genes in rubrospinal neurons following axotomy in rat. Eur J Neurosci 1993;5: 203-209.
    • (1993) Eur J Neurosci , vol.5 , pp. 203-209
    • Jenkins, R.1    Tetzlaff, W.2    Hunt, S.P.3
  • 20
    • 0028854073 scopus 로고
    • B-50 (GAP-43) immunoreactivity is rarely detected within intact catecholaminergic and serotonergic axons innervating the brain and spinal cord of the adult rat, but is associated with these axons following lesion
    • Alonso G, Ridet JL, Oestreicher AB, Gispen WH, Privat A. B-50 (GAP-43) immunoreactivity is rarely detected within intact catecholaminergic and serotonergic axons innervating the brain and spinal cord of the adult rat, but is associated with these axons following lesion. Exp Neurol 1995;134: 35-48.
    • (1995) Exp Neurol , vol.134 , pp. 35-48
    • Alonso, G.1    Ridet, J.L.2    Oestreicher, A.B.3    Gispen, W.H.4    Privat, A.5
  • 21
    • 0141783851 scopus 로고    scopus 로고
    • betaII-tubulin and GAP 43 mRNA expression in chronically injured neurons of the red nucleus after a second spinal cord injury
    • Storer PD, Houle JD. betaII-tubulin and GAP 43 mRNA expression in chronically injured neurons of the red nucleus after a second spinal cord injury. Exp Neurol 2003;183: 537-547.
    • (2003) Exp Neurol , vol.183 , pp. 537-547
    • Storer, P.D.1    Houle, J.D.2
  • 22
    • 0242299286 scopus 로고    scopus 로고
    • Treatment of chronically injured spinal cord with neurotrophic factors stimulates betaII-tubulin and GAP-43 expression in rubrospinal tract neurons
    • Storer PD, Dolbeare D, Houle JD. Treatment of chronically injured spinal cord with neurotrophic factors stimulates betaII-tubulin and GAP-43 expression in rubrospinal tract neurons. J Neurosci Res 2003;74: 502-511.
    • (2003) J Neurosci Res , vol.74 , pp. 502-511
    • Storer, P.D.1    Dolbeare, D.2    Houle, J.D.3
  • 23
    • 31544480379 scopus 로고    scopus 로고
    • Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord
    • Wong LF, Lindner R, Puttagunta R, Di Giovanni S. Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord. Nat Neurosci 2006;9: 243-250.
    • (2006) Nat Neurosci , vol.9 , pp. 243-250
    • Wong, L.F.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 24
    • 77956187905 scopus 로고    scopus 로고
    • PTEN deletion enhances the regenerative ability of adult corticospinal neurons
    • Liu K, Lindner R, Puttagunta R, Di Giovanni S. PTEN deletion enhances the regenerative ability of adult corticospinal neurons. Nat Neurosci 2010;13: 1075-1081.
    • (2010) Nat Neurosci , vol.13 , pp. 1075-1081
    • Liu, K.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 27
    • 77952581350 scopus 로고    scopus 로고
    • Long non-coding RNAs in nervous system function and disease
    • Qureshi IA, Mattick JS, Mehler MF. Long non-coding RNAs in nervous system function and disease. Brain Res 2010;1338: 20-35.
    • (2010) Brain Res , vol.1338 , pp. 20-35
    • Qureshi, I.A.1    Mattick, J.S.2    Mehler, M.F.3
  • 28
    • 77958605856 scopus 로고    scopus 로고
    • Epigenetic choreographers of neurogenesis in the adult mammalian brain
    • Ma DK, Lindner R, Puttagunta R, Di Giovanni S. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat Neurosci 2010;13: 1338-1344.
    • (2010) Nat Neurosci , vol.13 , pp. 1338-1344
    • Ma, D.K.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 29
    • 82755161786 scopus 로고    scopus 로고
    • Epigenetic regulation of microRNAs in cancer: an integrated review of literature
    • Kunej T, Lindner R, Puttagunta R, Di Giovanni S. Epigenetic regulation of microRNAs in cancer: an integrated review of literature. Mutat Res 2011;717: 77-84.
    • (2011) Mutat Res , vol.717 , pp. 77-84
    • Kunej, T.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 30
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007;128: 693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 31
    • 34249299791 scopus 로고    scopus 로고
    • The complex language of chromatin regulation during transcription
    • Berger SL. The complex language of chromatin regulation during transcription. Nature 2007;447: 407-412.
    • (2007) Nature , vol.447 , pp. 407-412
    • Berger, S.L.1
  • 32
    • 34247368534 scopus 로고    scopus 로고
    • Epigenetics in development
    • Kiefer JC. Epigenetics in development. Dev Dyn 2007;236: 1144-1156.
    • (2007) Dev Dyn , vol.236 , pp. 1144-1156
    • Kiefer, J.C.1
  • 33
    • 77957339220 scopus 로고    scopus 로고
    • Interplay between different epigenetic modifications and mechanisms
    • Murr R. Interplay between different epigenetic modifications and mechanisms. Adv Genet 2010;70: 101-141.
    • (2010) Adv Genet , vol.70 , pp. 101-141
    • Murr, R.1
  • 34
    • 0034968819 scopus 로고    scopus 로고
    • Methylated cytosine and the brain: a new base for neuroscience
    • Tucker KL. Methylated cytosine and the brain: a new base for neuroscience. Neuron 2001;30: 649-652.
    • (2001) Neuron , vol.30 , pp. 649-652
    • Tucker, K.L.1
  • 35
    • 71749084889 scopus 로고    scopus 로고
    • The role of DNA methylation in the central nervous system and neuropsychiatric disorders
    • Feng J, Fan G. The role of DNA methylation in the central nervous system and neuropsychiatric disorders. Int Rev Neurobiol 2009;89: 67-84.
    • (2009) Int Rev Neurobiol , vol.89 , pp. 67-84
    • Feng, J.1    Fan, G.2
  • 36
    • 77958580776 scopus 로고    scopus 로고
    • DNA methylation and memory formation
    • Day JJ, Sweatt JD. DNA methylation and memory formation. Nat Neurosci 2010;13: 1319-1323.
    • (2010) Nat Neurosci , vol.13 , pp. 1319-1323
    • Day, J.J.1    Sweatt, J.D.2
  • 37
    • 24144490659 scopus 로고    scopus 로고
    • Chromatin, DNA methylation and neuron gene regulation-the purpose of the package
    • Sharma RP, Grayson DR, Guidotti A, Costa E. Chromatin, DNA methylation and neuron gene regulation-the purpose of the package. J Psychiatry Neurosci 2005;30: 257-263.
    • (2005) J Psychiatry Neurosci , vol.30 , pp. 257-263
    • Sharma, R.P.1    Grayson, D.R.2    Guidotti, A.3    Costa, E.4
  • 38
    • 77955709610 scopus 로고    scopus 로고
    • HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation
    • Gaub P, Lindner R, Puttagunta R, Di Giovanni S. HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation. Cell Death Differ 2010;17: 1392-1408.
    • (2010) Cell Death Differ , vol.17 , pp. 1392-1408
    • Gaub, P.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 39
    • 84864281471 scopus 로고    scopus 로고
    • The histone acetyltransferase p300 promotes intrinsic axonal regeneration
    • Gaub P, Lindner R, Puttagunta R, Di Giovanni S. The histone acetyltransferase p300 promotes intrinsic axonal regeneration. Brain 2011;134: 2134-2148.
    • (2011) Brain , vol.134 , pp. 2134-2148
    • Gaub, P.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 40
    • 77951810285 scopus 로고    scopus 로고
    • Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation
    • Iskandar BJ, Lindner R, Puttagunta R, Di Giovanni S. Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest 2010;120: 1603-1616.
    • (2010) J Clin Invest , vol.120 , pp. 1603-1616
    • Iskandar, B.J.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 41
    • 84868142988 scopus 로고    scopus 로고
    • The nuclear events guiding successful nerve regeneration
    • Kiryu-Seo S, Kiyama H. The nuclear events guiding successful nerve regeneration. Front Mol Neurosci 2011;4: 53.
    • (2011) Front Mol Neurosci , vol.4 , pp. 53
    • Kiryu-Seo, S.1    Kiyama, H.2
  • 43
    • 33646926758 scopus 로고    scopus 로고
    • Dynamic nucleosomes and gene transcription
    • Mellor, J. Dynamic nucleosomes and gene transcription. Trends Genet 2006;22: 320-329.
    • (2006) Trends Genet , vol.22 , pp. 320-329
    • Mellor, J.1
  • 44
    • 34547924046 scopus 로고    scopus 로고
    • HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention
    • Yang XJ, Seto E. HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention. Oncogene 2007;26: 5310-5318.
    • (2007) Oncogene , vol.26 , pp. 5310-5318
    • Yang, X.J.1    Seto, E.2
  • 45
    • 33745632390 scopus 로고    scopus 로고
    • The epigenetic magic of histone lysine methylation
    • Jenuwein T. The epigenetic magic of histone lysine methylation. FEBS J 2006;273: 3121-3135.
    • (2006) FEBS J , vol.273 , pp. 3121-3135
    • Jenuwein, T.1
  • 46
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 2007;447: 425-432.
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 47
    • 77649267695 scopus 로고    scopus 로고
    • Dynamic changes in the human methylome during differentiation
    • Laurent L, Lindner R, Puttagunta R, Di Giovanni S. Dynamic changes in the human methylome during differentiation. Genome Res 2010;20: 320-331.
    • (2010) Genome Res , vol.20 , pp. 320-331
    • Laurent, L.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 48
    • 77956095231 scopus 로고    scopus 로고
    • Active DNA demethylation: many roads lead to Rome
    • Wu SC, Zhang Y. Active DNA demethylation: many roads lead to Rome. Nat Rev Mol Cell Biol 2010;11: 607-620.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 607-620
    • Wu, S.C.1    Zhang, Y.2
  • 49
    • 70450217879 scopus 로고    scopus 로고
    • Human DNA methylomes at base resolution show widespread epigenomic differences
    • Lister R, Lindner R, Puttagunta R, Di Giovanni S. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009;462: 315-322.
    • (2009) Nature , vol.462 , pp. 315-322
    • Lister, R.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 50
    • 0026742792 scopus 로고
    • CpG islands as gene markers in the human genome
    • Larsen F, Gundersen G, Lopez R, Prydz H. CpG islands as gene markers in the human genome. Genomics 1992;13: 1095-1107.
    • (1992) Genomics , vol.13 , pp. 1095-1107
    • Larsen, F.1    Gundersen, G.2    Lopez, R.3    Prydz, H.4
  • 51
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002;16: 6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 52
    • 38949212693 scopus 로고    scopus 로고
    • A novel CpG island set identifies tissue-specific methylation at developmental gene loci
    • e22
    • Illingworth R, Lindner R, Puttagunta R, Di Giovanni S. A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol 2008;6: e22.
    • (2008) PLoS Biol , pp. 6
    • Illingworth, R.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 53
    • 78049419464 scopus 로고    scopus 로고
    • Orphan CpG islands identify numerous conserved promoters in the mammalian genome
    • e1001134
    • Illingworth RS, Lindner R, Puttagunta R, Di Giovanni S. Orphan CpG islands identify numerous conserved promoters in the mammalian genome. PLoS Genet 2010;6: e1001134.
    • (2010) PLoS Genet , pp. 6
    • Illingworth, R.S.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 54
    • 77954504873 scopus 로고    scopus 로고
    • Conserved role of intragenic DNA methylation in regulating alternative promoters
    • Maunakea AK, Lindner R, Puttagunta R, Di Giovanni S. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature 2010;466: 253-257.
    • (2010) Nature , vol.466 , pp. 253-257
    • Maunakea, A.K.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 55
    • 0027141519 scopus 로고
    • Number of CpG islands and genes in human and mouse
    • Antequera F, Bird A. Number of CpG islands and genes in human and mouse. Proc Natl Acad Sci U S A 1993;90: 11995-11999.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 11995-11999
    • Antequera, F.1    Bird, A.2
  • 56
    • 31944432339 scopus 로고    scopus 로고
    • A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters
    • Saxonov S, Berg P, Brutlag DL. A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters. Proc Natl Acad Sci U S A 2006;103: 1412-1417.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 1412-1417
    • Saxonov, S.1    Berg, P.2    Brutlag, D.L.3
  • 57
    • 34047116826 scopus 로고    scopus 로고
    • Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
    • Weber M, Lindner R, Puttagunta R, Di Giovanni S. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007;39: 457-466.
    • (2007) Nat Genet , vol.39 , pp. 457-466
    • Weber, M.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 58
    • 0026747761 scopus 로고
    • Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
    • Lewis JD, Lindner R, Puttagunta R, Di Giovanni S. Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 1992;69: 905-914.
    • (1992) Cell , vol.69 , pp. 905-914
    • Lewis, J.D.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 59
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir RE, Lindner R, Puttagunta R, Di Giovanni S. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 1999;23: 185-188.
    • (1999) Nat Genet , vol.23 , pp. 185-188
    • Amir, R.E.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 60
    • 69249220176 scopus 로고    scopus 로고
    • DNA methylation and methyl-CpG binding proteins: developmental requirements and function
    • Bogdanovic O, Veenstra GJ. DNA methylation and methyl-CpG binding proteins: developmental requirements and function. Chromosoma 2009;118: 549-565.
    • (2009) Chromosoma , vol.118 , pp. 549-565
    • Bogdanovic, O.1    Veenstra, G.J.2
  • 61
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan X, Lindner R, Puttagunta R, Di Giovanni S. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 1998;393: 386-389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 62
    • 0034634549 scopus 로고    scopus 로고
    • The minimal repression domain of MBD2b overlaps with the methyl-CpG-binding domain and binds directly to Sin3A
    • Boeke J, Ammerpohl O, Kegel S, Moehren U, Renkawitz R. The minimal repression domain of MBD2b overlaps with the methyl-CpG-binding domain and binds directly to Sin3A. J Biol Chem 2000;275: 34963-34967.
    • (2000) J Biol Chem , vol.275 , pp. 34963-34967
    • Boeke, J.1    Ammerpohl, O.2    Kegel, S.3    Moehren, U.4    Renkawitz, R.5
  • 63
    • 84864301890 scopus 로고    scopus 로고
    • The role of methyl-binding proteins in chromatin organization and epigenome maintenance
    • Fournier A, Sasai N, Nakao M, Defossez PA. The role of methyl-binding proteins in chromatin organization and epigenome maintenance. Brief Funct Genomics 2012;11: 251-264.
    • (2012) Brief Funct Genomics , vol.11 , pp. 251-264
    • Fournier, A.1    Sasai, N.2    Nakao, M.3    Defossez, P.A.4
  • 64
    • 0035054930 scopus 로고    scopus 로고
    • Angelman syndrome phenotype associated with mutations in MECP2, a gene encoding a methyl CpG binding protein
    • Watson P, Lindner R, Puttagunta R, Di Giovanni S. Angelman syndrome phenotype associated with mutations in MECP2, a gene encoding a methyl CpG binding protein. J Med Genet 2001;38: 224-228.
    • (2001) J Med Genet , vol.38 , pp. 224-228
    • Watson, P.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 65
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • Chahrour M, Lindner R, Puttagunta R, Di Giovanni S. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 2008;320: 1224-1229.
    • (2008) Science , vol.320 , pp. 1224-1229
    • Chahrour, M.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 66
    • 79955538772 scopus 로고    scopus 로고
    • In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system
    • Diaz de Leon-Guerrero S, Pedraza-Alva G, Perez-Martinez L. In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system. Eur J Neurosci 2011;33: 1563-1574.
    • (2011) Eur J Neurosci , vol.33 , pp. 1563-1574
    • Diaz de Leon-Guerrero, S.1    Pedraza-Alva, G.2    Perez-Martinez, L.3
  • 67
    • 79958025812 scopus 로고    scopus 로고
    • Complexities of Rett Syndrome and MeCP2
    • Samaco RC, Neul JL. Complexities of Rett Syndrome and MeCP2. J Neurosci 2011;31: 7951-7959.
    • (2011) J Neurosci , vol.31 , pp. 7951-7959
    • Samaco, R.C.1    Neul, J.L.2
  • 68
  • 69
    • 0037081840 scopus 로고    scopus 로고
    • Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation
    • Shahbazian MD, Antalffy B, Armstrong DL, Zoghbi HY. Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation. Hum Mol Genet 2002;11: 115-124.
    • (2002) Hum Mol Genet , vol.11 , pp. 115-124
    • Shahbazian, M.D.1    Antalffy, B.2    Armstrong, D.L.3    Zoghbi, H.Y.4
  • 70
    • 20444471996 scopus 로고    scopus 로고
    • A transcriptional repressor MeCP2 causing Rett syndrome is expressed in embryonic non-neuronal cells and controls their growth
    • Nagai K, Miyake K, Kubota T. A transcriptional repressor MeCP2 causing Rett syndrome is expressed in embryonic non-neuronal cells and controls their growth. Brain Res Dev Brain Res 2005;157: 103-106.
    • (2005) Brain Res Dev Brain Res , vol.157 , pp. 103-106
    • Nagai, K.1    Miyake, K.2    Kubota, T.3
  • 71
    • 65549144456 scopus 로고    scopus 로고
    • Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions
    • Maezawa I, Swanberg S, Harvey D, LaSalle JM, Jin LW. Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions. J Neurosci 2009;29: 5051-5061.
    • (2009) J Neurosci , vol.29 , pp. 5051-5061
    • Maezawa, I.1    Swanberg, S.2    Harvey, D.3    LaSalle, J.M.4    Jin, L.W.5
  • 72
    • 84857385884 scopus 로고    scopus 로고
    • The expression of spinal methyl-CpG-binding protein 2, DNA methyltransferases and histone deacetylases is modulated in persistent pain states
    • Tochiki KK, Cunningham J, Hunt SP, Geranton SM. The expression of spinal methyl-CpG-binding protein 2, DNA methyltransferases and histone deacetylases is modulated in persistent pain states. Mol Pain 2012;8: 14.
    • (2012) Mol Pain , vol.8 , pp. 14
    • Tochiki, K.K.1    Cunningham, J.2    Hunt, S.P.3    Geranton, S.M.4
  • 73
    • 84867633471 scopus 로고    scopus 로고
    • Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice
    • Li W, Calfa G, Larimore J, Pozzo-Miller L. Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice. Proc Natl Acad Sci U S A 2012;109: 17087-17092.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 17087-17092
    • Li, W.1    Calfa, G.2    Larimore, J.3    Pozzo-Miller, L.4
  • 74
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • Martinowich K, Lindner R, Puttagunta R, Di Giovanni S. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 2003;302: 890-893.
    • (2003) Science , vol.302 , pp. 890-893
    • Martinowich, K.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 75
    • 84863808547 scopus 로고    scopus 로고
    • SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression
    • Zocchi L, Sassone-Corsi P. SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression. Epigenetics 2012;7: 695-700.
    • (2012) Epigenetics , vol.7 , pp. 695-700
    • Zocchi, L.1    Sassone-Corsi, P.2
  • 76
    • 84864400984 scopus 로고    scopus 로고
    • Elevated IKKalpha accelerates the differentiation of human neuronal progenitor cells and induces MeCP2-dependent BDNF expression
    • Khoshnan A, Patterson PH. Elevated IKKalpha accelerates the differentiation of human neuronal progenitor cells and induces MeCP2-dependent BDNF expression. PLoS One 2012;7: e41794.
    • (2012) PLoS One , vol.7
    • Khoshnan, A.1    Patterson, P.H.2
  • 77
    • 0242332183 scopus 로고    scopus 로고
    • Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
    • Chen WG, Lindner R, Puttagunta R, Di Giovanni S. Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science 2003;302: 885-889.
    • (2003) Science , vol.302 , pp. 885-889
    • Chen, W.G.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 78
    • 54849426071 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory
    • Lubin FD, Roth TL, Sweatt JD. Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci 2008;28: 10576-10586.
    • (2008) J Neurosci , vol.28 , pp. 10576-10586
    • Lubin, F.D.1    Roth, T.L.2    Sweatt, J.D.3
  • 79
    • 8844263909 scopus 로고    scopus 로고
    • Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo
    • Gao Y, Lindner R, Puttagunta R, Di Giovanni S. Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo. Neuron 2004;44: 609-621.
    • (2004) Neuron , vol.44 , pp. 609-621
    • Gao, Y.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 80
    • 38649128184 scopus 로고    scopus 로고
    • The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury
    • Hannila SS, Filbin MT. The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury. Exp Neurol 2008;209: 321-332.
    • (2008) Exp Neurol , vol.209 , pp. 321-332
    • Hannila, S.S.1    Filbin, M.T.2
  • 81
    • 7244243971 scopus 로고    scopus 로고
    • MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions
    • Kishi N, Macklis JD. MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions. Mol Cell Neurosci 2004;27: 306-321.
    • (2004) Mol Cell Neurosci , vol.27 , pp. 306-321
    • Kishi, N.1    Macklis, J.D.2
  • 83
    • 77953545864 scopus 로고    scopus 로고
    • The role of MeCP2 in brain development and neurodevelopmental disorders
    • Gonzales ML, LaSalle JM. The role of MeCP2 in brain development and neurodevelopmental disorders. Curr Psychiatry Rep 2010;12: 127-134.
    • (2010) Curr Psychiatry Rep , vol.12 , pp. 127-134
    • Gonzales, M.L.1    LaSalle, J.M.2
  • 84
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999;99: 247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 85
    • 33749241112 scopus 로고    scopus 로고
    • Transition of mouse de novo methyltransferases expression from Dnmt3b to Dnmt3a during neural progenitor cell development
    • Watanabe D, Uchiyama K, Hanaoka K. Transition of mouse de novo methyltransferases expression from Dnmt3b to Dnmt3a during neural progenitor cell development. Neuroscience 2006;142: 727-737.
    • (2006) Neuroscience , vol.142 , pp. 727-737
    • Watanabe, D.1    Uchiyama, K.2    Hanaoka, K.3
  • 86
    • 0034193368 scopus 로고    scopus 로고
    • DNA methyltransferase contributes to delayed ischemic brain injury
    • Endres M, Lindner R, Puttagunta R, Di Giovanni S. DNA methyltransferase contributes to delayed ischemic brain injury. J Neurosci 2000;20: 3175-3181.
    • (2000) J Neurosci , vol.20 , pp. 3175-3181
    • Endres, M.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 87
    • 16444381345 scopus 로고    scopus 로고
    • Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
    • Feng J, Chang H, Li E, Fan G. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J Neurosci Res 2005;79: 734-746.
    • (2005) J Neurosci Res , vol.79 , pp. 734-746
    • Feng, J.1    Chang, H.2    Li, E.3    Fan, G.4
  • 88
    • 81255143014 scopus 로고    scopus 로고
    • Epigenetic regulation of motor neuron cell death through DNA methylation
    • Chestnut BA, Lindner R, Puttagunta R, Di Giovanni S. Epigenetic regulation of motor neuron cell death through DNA methylation. J Neurosci 2011;31: 16619-16636.
    • (2011) J Neurosci , vol.31 , pp. 16619-16636
    • Chestnut, B.A.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 89
    • 0025185415 scopus 로고
    • Changes of DNA methylation level during pre- and postnatal periods in mice
    • Tawa R, Ono T, Kurishita A, Okada S, Hirose S. Changes of DNA methylation level during pre- and postnatal periods in mice. Differentiation 1990;45: 44-48.
    • (1990) Differentiation , vol.45 , pp. 44-48
    • Tawa, R.1    Ono, T.2    Kurishita, A.3    Okada, S.4    Hirose, S.5
  • 90
    • 0028267714 scopus 로고
    • Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice
    • Goto K, Lindner R, Puttagunta R, Di Giovanni S. Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation 1994;56: 39-44.
    • (1994) Differentiation , vol.56 , pp. 39-44
    • Goto, K.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 91
    • 0030006003 scopus 로고    scopus 로고
    • DNA mismatch repair and DNA methylation in adult brain neurons
    • Brooks PJ, Marietta C, Goldman D. DNA mismatch repair and DNA methylation in adult brain neurons. J Neurosci 1996;16: 939-945.
    • (1996) J Neurosci , vol.16 , pp. 939-945
    • Brooks, P.J.1    Marietta, C.2    Goldman, D.3
  • 92
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • Miller CA, Sweatt JD. Covalent modification of DNA regulates memory formation. Neuron 2007;53: 857-869.
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 93
    • 77958526499 scopus 로고    scopus 로고
    • Epigenetic regulation of the neural transcriptome: the meaning of the marks
    • Meaney MJ, Ferguson-Smith AC. Epigenetic regulation of the neural transcriptome: the meaning of the marks. Nat Neurosci 2010;13: 1313-1318.
    • (2010) Nat Neurosci , vol.13 , pp. 1313-1318
    • Meaney, M.J.1    Ferguson-Smith, A.C.2
  • 94
    • 77953429462 scopus 로고    scopus 로고
    • Brain function and chromatin plasticity
    • Dulac C. Brain function and chromatin plasticity. Nature 2010;465: 728-735.
    • (2010) Nature , vol.465 , pp. 728-735
    • Dulac, C.1
  • 95
    • 78651472592 scopus 로고    scopus 로고
    • DNA methylation-mediated control of learning and memory
    • Yu NK, Baek SH, Kaang BK. DNA methylation-mediated control of learning and memory. Mol Brain 2011;4: 5.
    • (2011) Mol Brain , vol.4 , pp. 5
    • Yu, N.K.1    Baek, S.H.2    Kaang, B.K.3
  • 96
    • 65649150326 scopus 로고    scopus 로고
    • Folic acid, neurodegenerative and neuropsychiatric disease
    • Kronenberg G, Colla M, Endres M. Folic acid, neurodegenerative and neuropsychiatric disease. Curr Mol Med 2009;9: 315-323.
    • (2009) Curr Mol Med , vol.9 , pp. 315-323
    • Kronenberg, G.1    Colla, M.2    Endres, M.3
  • 97
    • 33846933274 scopus 로고    scopus 로고
    • Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
    • Barreto G, Lindner R, Puttagunta R, Di Giovanni S. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 2007;445: 671-675.
    • (2007) Nature , vol.445 , pp. 671-675
    • Barreto, G.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 98
    • 0042819716 scopus 로고    scopus 로고
    • Selective up-regulation of the growth arrest DNA damage-inducible gene Gadd45 alpha in sensory and motor neurons after peripheral nerve injury
    • Befort K, Karchewski L, Lanoue C, Woolf CJ. Selective up-regulation of the growth arrest DNA damage-inducible gene Gadd45 alpha in sensory and motor neurons after peripheral nerve injury. Eur J Neurosci 2003;18: 911-922.
    • (2003) Eur J Neurosci , vol.18 , pp. 911-922
    • Befort, K.1    Karchewski, L.2    Lanoue, C.3    Woolf, C.J.4
  • 99
    • 46249112085 scopus 로고    scopus 로고
    • Combinatorial patterns of histone acetylations and methylations in the human genome
    • Wang Z, Lindner R, Puttagunta R, Di Giovanni S. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 2008;40: 897-903.
    • (2008) Nat Genet , vol.40 , pp. 897-903
    • Wang, Z.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 100
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • Bannister AJ, Kouzarides T. Regulation of chromatin by histone modifications. Cell Res 2011;21: 381-395.
    • (2011) Cell Res , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 101
    • 0034051227 scopus 로고    scopus 로고
    • Acetylation of histones and transcription-related factors
    • Sterner DE, Berger SL. Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev 2000;64: 435-459.
    • (2000) Microbiol Mol Biol Rev , vol.64 , pp. 435-459
    • Sterner, D.E.1    Berger, S.L.2
  • 103
    • 34547911052 scopus 로고    scopus 로고
    • Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design
    • Hodawadekar SC, Marmorstein R. Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design. Oncogene 2007;26: 5528-5540.
    • (2007) Oncogene , vol.26 , pp. 5528-5540
    • Hodawadekar, S.C.1    Marmorstein, R.2
  • 104
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD. Translating the histone code. Science 2001;293: 1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 105
    • 0031678679 scopus 로고    scopus 로고
    • Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates
    • Xu W, Edmondson DG, Roth SY. Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates. Mol Cell Biol 1998;18: 5659-5669.
    • (1998) Mol Cell Biol , vol.18 , pp. 5659-5669
    • Xu, W.1    Edmondson, D.G.2    Roth, S.Y.3
  • 106
    • 0030606239 scopus 로고    scopus 로고
    • The transcriptional coactivators p300 and CBP are histone acetyltransferases
    • Ogryzko VV, Schiltz RL, Russanova V, Howard BH, Nakatani Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 1996;87: 953-959.
    • (1996) Cell , vol.87 , pp. 953-959
    • Ogryzko, V.V.1    Schiltz, R.L.2    Russanova, V.3    Howard, B.H.4    Nakatani, Y.5
  • 107
    • 0036840497 scopus 로고    scopus 로고
    • p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro
    • Wallberg AE, Pedersen K, Lendahl U, Roeder RG. p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro. Mol Cell Biol 2002;22: 7812-7819.
    • (2002) Mol Cell Biol , vol.22 , pp. 7812-7819
    • Wallberg, A.E.1    Pedersen, K.2    Lendahl, U.3    Roeder, R.G.4
  • 108
    • 78751611793 scopus 로고    scopus 로고
    • Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation
    • Jin Q, Lindner R, Puttagunta R, Di Giovanni S. Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation. EMBO J 2011;30: 249-262.
    • (2011) EMBO J , vol.30 , pp. 249-262
    • Jin, Q.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 109
    • 43649104766 scopus 로고    scopus 로고
    • Altered memory capacities and response to stress in p300/CBP-associated factor (PCAF) histone acetylase knockout mice
    • Maurice T, Lindner R, Puttagunta R, Di Giovanni S. Altered memory capacities and response to stress in p300/CBP-associated factor (PCAF) histone acetylase knockout mice. Neuropsychopharmacology 2008;33: 1584-1602.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 1584-1602
    • Maurice, T.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 110
    • 19944429405 scopus 로고    scopus 로고
    • Nerve growth factor receptor signaling induces histone acetyltransferase domain-dependent nuclear translocation of p300/CREB-binding protein-associated factor and hGCN5 acetyltransferases
    • Wong K, Lindner R, Puttagunta R, Di Giovanni S. Nerve growth factor receptor signaling induces histone acetyltransferase domain-dependent nuclear translocation of p300/CREB-binding protein-associated factor and hGCN5 acetyltransferases. J Biol Chem 2004;279: 55667-55674.
    • (2004) J Biol Chem , vol.279 , pp. 55667-55674
    • Wong, K.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 111
    • 53249088036 scopus 로고    scopus 로고
    • PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia
    • Xenaki G, Lindner R, Puttagunta R, Di Giovanni S. PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia. Oncogene 2008;27: 5785-5796.
    • (2008) Oncogene , vol.27 , pp. 5785-5796
    • Xenaki, G.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 112
    • 0031149046 scopus 로고    scopus 로고
    • The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration
    • Herdegen T, Skene P, Bahr M. The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration. Trends Neurosci 1997;20: 227-231.
    • (1997) Trends Neurosci , vol.20 , pp. 227-231
    • Herdegen, T.1    Skene, P.2    Bahr, M.3
  • 113
    • 33748366999 scopus 로고    scopus 로고
    • The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration
    • Di Giovanni S, Lindner R, Puttagunta R. The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration. EMBO J 2006;25: 4084-4096.
    • (2006) EMBO J , vol.25 , pp. 4084-4096
    • Di Giovanni, S.1    Lindner, R.2    Puttagunta, R.3
  • 114
    • 0038399824 scopus 로고    scopus 로고
    • Functional interplay between CBP and PCAF in acetylation and regulation of transcription factor KLF13 activity
    • Song CZ, Keller K, Chen Y, Stamatoyannopoulos G. Functional interplay between CBP and PCAF in acetylation and regulation of transcription factor KLF13 activity. J Mol Biol 2003;329: 207-215.
    • (2003) J Mol Biol , vol.329 , pp. 207-215
    • Song, C.Z.1    Keller, K.2    Chen, Y.3    Stamatoyannopoulos, G.4
  • 115
    • 0032931767 scopus 로고    scopus 로고
    • The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding
    • Sharma A, Lindner R, Puttagunta R, Di Giovanni S. The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding. Mol Cell Biol 1999;19: 704-713.
    • (1999) Mol Cell Biol , vol.19 , pp. 704-713
    • Sharma, A.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 116
    • 0037111980 scopus 로고    scopus 로고
    • Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure
    • Guan Z, Lindner R, Puttagunta R, Di Giovanni S. Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure. Cell 2002;111: 483-493.
    • (2002) Cell , vol.111 , pp. 483-493
    • Guan, Z.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 117
    • 0031890958 scopus 로고    scopus 로고
    • Expression of Jun, Fos, and ATF-2 proteins in axotomized explanted and cultured adult rat dorsal root ganglia
    • Buschmann T, Lindner R, Puttagunta R, Di Giovanni S. Expression of Jun, Fos, and ATF-2 proteins in axotomized explanted and cultured adult rat dorsal root ganglia. Neuroscience 1998;84: 163-176.
    • (1998) Neuroscience , vol.84 , pp. 163-176
    • Buschmann, T.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 118
    • 70649087176 scopus 로고    scopus 로고
    • Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats
    • e7820
    • Li MY, Lindner R, Puttagunta R, Di Giovanni S. Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats. PLoS One 2009;4: e7820.
    • (2009) PLoS One , pp. 4
    • Li, M.Y.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 119
    • 0030969516 scopus 로고    scopus 로고
    • Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression
    • Laherty CD, Lindner R, Puttagunta R, Di Giovanni S. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 1997;89: 349-356.
    • (1997) Cell , vol.89 , pp. 349-356
    • Laherty, C.D.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 120
    • 0034254857 scopus 로고    scopus 로고
    • NuRD and SIN3 histone deacetylase complexes in development
    • Ahringer J. NuRD and SIN3 histone deacetylase complexes in development. Trends Genet 2000;16: 351-356.
    • (2000) Trends Genet , vol.16 , pp. 351-356
    • Ahringer, J.1
  • 121
    • 55949085986 scopus 로고    scopus 로고
    • Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development
    • McDonel P, Costello I, Hendrich B. Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development. Int J Biochem Cell Biol 2009;41: 108-116.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 108-116
    • McDonel, P.1    Costello, I.2    Hendrich, B.3
  • 122
    • 9344252804 scopus 로고    scopus 로고
    • Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells
    • Hsieh J, Nakashima K, Kuwabara T, Mejia E, Gage FH. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci U S A 2004;101: 16659-16664.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 16659-16664
    • Hsieh, J.1    Nakashima, K.2    Kuwabara, T.3    Mejia, E.4    Gage, F.H.5
  • 123
    • 79958245644 scopus 로고    scopus 로고
    • In cortical neurons HDAC3 activity suppresses RD4-dependent SMRT export
    • Soriano FX, Hardingham GE. In cortical neurons HDAC3 activity suppresses RD4-dependent SMRT export. PLoS One 2011;6: e21056.
    • (2011) PLoS One , vol.6
    • Soriano, F.X.1    Hardingham, G.E.2
  • 124
    • 79960230042 scopus 로고    scopus 로고
    • RA-RAR-{beta} counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression
    • Puttagunta R, Lindner R, Puttagunta R, Di Giovanni S. RA-RAR-{beta} counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression. J Cell Biol 2011;193: 1147-1156.
    • (2011) J Cell Biol , vol.193 , pp. 1147-1156
    • Puttagunta, R.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 125
    • 79953186033 scopus 로고    scopus 로고
    • HDAC-mediated deacetylation of NF-kappaB is critical for Schwann cell myelination
    • Chen Y, Lindner R, Puttagunta R, Di Giovanni S. HDAC-mediated deacetylation of NF-kappaB is critical for Schwann cell myelination. Nat Neurosci 2011;14: 437-441.
    • (2011) Nat Neurosci , vol.14 , pp. 437-441
    • Chen, Y.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 126
    • 73349143672 scopus 로고    scopus 로고
    • HDAC6 is a target for protection and regeneration following injury in the nervous system
    • Rivieccio MA, Lindner R, Puttagunta R, Di Giovanni S. HDAC6 is a target for protection and regeneration following injury in the nervous system. Proc Natl Acad Sci U S A 2009;106: 19599-19604.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 19599-19604
    • Rivieccio, M.A.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 127
    • 57049151436 scopus 로고    scopus 로고
    • Epigenetic principles and mechanisms underlying nervous system functions in health and disease
    • Mehler MF. Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog Neurobiol 2008;86: 305-341.
    • (2008) Prog Neurobiol , vol.86 , pp. 305-341
    • Mehler, M.F.1
  • 128
    • 77956398534 scopus 로고    scopus 로고
    • Brain plasticity, memory and neurological disorders: an epigenetic perspective
    • Lockett GA, Wilkes F, Maleszka R. Brain plasticity, memory and neurological disorders: an epigenetic perspective. Neuroreport 2010;21: 909-913.
    • (2010) Neuroreport , vol.21 , pp. 909-913
    • Lockett, G.A.1    Wilkes, F.2    Maleszka, R.3
  • 129
    • 33645357786 scopus 로고    scopus 로고
    • Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action
    • Tsankova NM, Lindner R, Puttagunta R, Di Giovanni S. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 2006;9: 519-525.
    • (2006) Nat Neurosci , vol.9 , pp. 519-525
    • Tsankova, N.M.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 130
    • 62849115047 scopus 로고    scopus 로고
    • A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth, and regeneration
    • Tedeschi A, Nguyen T, Puttagunta R, Gaub P, Di Giovanni S. A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth, and regeneration. Cell Death Differ 2009;16: 543-554.
    • (2009) Cell Death Differ , vol.16 , pp. 543-554
    • Tedeschi, A.1    Nguyen, T.2    Puttagunta, R.3    Gaub, P.4    Di Giovanni, S.5
  • 131
    • 84867027499 scopus 로고    scopus 로고
    • p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury
    • Floriddia EM, Lindner R, Puttagunta R, Di Giovanni S. p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury. J Neurosci 2012;32: 13956-13970.
    • (2012) J Neurosci , vol.32 , pp. 13956-13970
    • Floriddia, E.M.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 132
    • 72849124516 scopus 로고    scopus 로고
    • The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse
    • Tedeschi A, Lindner R, Puttagunta R, Di Giovanni S. The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse. J Neurosci 2009;29: 15155-15160.
    • (2009) J Neurosci , vol.29 , pp. 15155-15160
    • Tedeschi, A.1    Lindner, R.2    Puttagunta, R.3    Di Giovanni, S.4
  • 133
    • 77950860161 scopus 로고    scopus 로고
    • Retrograde signaling in axonal regeneration
    • Rishal I, Fainzilber M. Retrograde signaling in axonal regeneration. Exp Neurol 2009;223: 5-10.
    • (2009) Exp Neurol , vol.223 , pp. 5-10
    • Rishal, I.1    Fainzilber, M.2


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