Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury

Neuron

Volumn 23, Issue 1, 1999, Pages 83-91

  Neumann, Simona ^a   Woolf, Clifford J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GROWTH RATE; INFERIOR COLLICULUS; MALE; NERVE FIBER; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NERVE LESION; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SENSORY NERVE CELL; SPINAL CORD INJURY; SUPERIOR COLLICULUS;

EID: 0033137077     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80755-2     Document Type: Article

References (40)

1. Aigner, L., Arber, S., Kaphammer, J.P., Laus, T., Schneider, C., BotTeri, F., Brenner, H.-R., and Caroni, P. (1995). Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell 83, 269-278.
2. Benfey, M., Bunger, U.R., Vidal Sanz, M., Bray, G.M., and Aguayo, A.J. (1985). Axonal regeneration from gaBAergic neurons in the adult rat thalamus. J. Neurocytol. 14, 279-296.
3. Bregman, B.S., Kunkel Bagden, E., McAtee, M., and O'Neill, A. (1989). Extension of the critical period for developmental plasticity of the corticospinal pathway. J. Comp. Neurol. 282, 355-370.
4. Bregman, B.S., Kunkel-Bagden, E., Schnell, L., Ning Dai, H., Gao, D., and Schwab, M.E. (1995). Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature 378, 498-501.
5. Bunge, R.P., Bunge, M.B., and Eldridge, C.F. (1986). Linkage between axonal ensheathment and basal lamina production by schwann cells. Annu. Rev. Neurosci. 9, 305-328.
6. Campbell, G., Lieberman, A.R., Anderson, P.N., and Turmaine, M. (1992). Regeneration of adult rat CNS axons into peripheral nerve autographs: Ultrastructural studies of the early stages of axonal sprouting and regenerative axonal growth. J. Neurocytol. 21, 755-782.
7. Chong, M.-S., Reynolds, M.L., Irwin, N., Coggeshall, R.E., Emson, P.C., Benowitz, L.I., and Woolf, C.J. (1994). GAP-43 expression in primary sensory neurons following central axotomy. J. Neurosci. 14(7), 4375-4384.
8. Chong, M.-S., Woolf, C.J., Turmaine, M., Emson, P.C., and AnderSon, P.N. (1996). Intrinsic vs extrinsic factors in determining the regeneration of the central processes of rat dorsal root ganglion neurons: The influence of a peripheral nerve graft. J. Comp. Neurol. 370, 97-104.
9. Coggeshall, R.E., Lekan, H.A., Doubell, T.P., Allchorne, A., and Woolf, C.J. (1997). Central changes in primary afferent fibers following peripheral nerve lesions. Neuroscience 77, 1115-1122.
10. David, S., and Aguayo, A.J. (1989). Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats. Science 214, 931-933.
11. Davies, S.J., Field, P.M., and Raisman, G. (1994). Long interfascicular axon growth from embryonic neurons transplanted into adult myelinated tracts. J. Neurosci. 14, 1596-1612.
12. Davies, S.J., Fitch, M.T., Memberg, S.P., Hall, A.K., Raisman, G., and Silver, J. (1997). Regeneration of adult axons in white matter tracts of the central nervous system. Nature 390, 680-683.
13. Edstrom, A., Ekstrom, P.A., and Tonge, D. (1996). Axonal outgrowth and neuronal apoptosis in cultured adult mouse dorsal root ganglion preparations: Effects of neurotrophins, of inhibition of neurotrophins actions and of prior axotomy. Neuroscience 75, 1165-1174.
14. Hu-Tsai, M., Woolf, C.J., Emson, P.C., and Winter, J. (1994). Neurite outgrowth and GAP-43 mRNA expression in cultured adult rat dorsal root ganglion neurons: Effects of NGF and prior axotomy. J. NeuRosci. Res. 39, 634-645.
15. Iwashita, Y., Kawaguchi, S., and Murata, M. (1994). Restoration of function by replacement of spinal cord segments in the rat. Nature 367, 167-170.
16. Jakeman, L.B., and Reier, P.J. (1991). Axonal projections between fetal spinal cord transplants and the adult rat spinal cord: A neuro- Anatomical tracing study of local interactions. J. Comp. Neurol. 307, 311-334.
17. Kleitman, N., Simon, O.K., Schachner, M., and Bunge, R.P. (1988). Growth of embryonic retinal neurites elicited by contact with Schwann cell surfaces is blocked by antibodies to L1. Exp. Neurol. 102, 298-306.
18. Lamotte, C.C., Kapadia, S.E., and Shapiro, C.M. (1991). Central projections of the sciatic, saphenous, median, and ulnar nerves of the rat demonstrated by transganglionic transport of choleragenoid- HRP (B-HRP) and wheat germ agglutinin-HRP (WGA-HRP). J. Comp. Neurol. 311, 546-562.
19. Li, Y., and Raisman, G. (1994). Schwann cells induce sprouting in motor and sensory axons in the adult rat spinal cord. J. Neurosci. 14, 4050-4063.
20. Li, Y., Field, P.M., and Raisman, G. (1997). Repair of adult corticospinal tract by transplants of olfactory ensheating cells. Science 277, 2000-2002.
21. Mesulam, M.M. (1978). Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: A non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. J. Histochem. Cytochem. 26, 106-117.
22. Oudega, M., Varon, S., and Hagg, T. (1994). Regeneration of adult rat sensory axons into intraspinal nerve grafts: Promoting effects of conditioning lesion and graft predegeneration. Exp. Neurol. 129, 194-206.
23. Pindzola, R.R., Doller, C., and Silver, J. (1993). Putative inhibitory extracellular matrix molecules at the dorsal root entry zone of the spinal cord during development and after root and sciatic nerve lesions. Dev. Biol. 156, 34-48.
24. Ramon Y Cajal, S. (1928). Degeneration and Regeneration Of The Nervous System. Translated by R.M. May, edited by J. DeFelipe and E.G. Jones (New York: Oxford University Press), 1991.
25. Richardson, P.M., and Issa, V.M.K. (1984). Peripheral injury enhances central regeneration of primary sensory neurones. Nature 309, 791-793.
26. Richardson, P.M., and Verge, V.M.K. (1986). The induction of a regenerative propensity in sensory neurons following peripheral axonal injury. J. Neurocytol. 15, 585-594.
27. Richardson, P.M., and Verge, V.M.K. (1987). Axonal regeneration in dorsal spinal roots is accelerated by peripheral axonal transection. Brain Res. 411, 406-408.
28. Richardson, P.M., McGuinness, U.M., and Aguayo, A.J. (1982). Peripheral nerve autografts to the rat spinal cord: Studies with axonal tracing methods. Brain Res. 237(1), 147-162.
29. Ritter, A.M., Lewin, G.R., Kremer, N.E., and Mendell, L.M. (1991). Requirement for nerve growth factor in the development of myelinated nociceptors in vivo. Nature 350, 500-502.
30. Schnell, L., and Schwab, M.E. (1990). Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature 343, 269-272.
31. Schnell, L., Schneider, R., Kolbeck, R., Barde, Y.-A., and Schwab, M.E. (1994). Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature 367, 170-173.
32. Schreyer, D.J., and Skene, J.H.P. (1991). Fate of GAP-43 in ascending spinal axons of DRG neurons after peripheral nerve injury: Delayed accumulation and correlation with regenerative potential. J. Neurosci. 11(12), 3738-3451.
33. Schreyer, D.J., and Skene, J.H.P. (1993). Injury-associated induction of GAP-43 expression displays axon branch specificity in rat dorsal root ganglion neurons. J. Neurobiol. 24, 959-970.
34. Schwab, M.E., and Bartholdi, D.(1996). Degeneration and regeneration of axons in the lesioned spinal cord. Physiol. Rev. 76, 319-370.
35. Smith, D.S., and Skene, J.H. (1997). A trascription-dependent switch controls competence of adult neurons for distinct modes of axon growth. J. Neurosci. 17, 343-358.
36. Vidai Sanz, M., Bunger, U.R., Bray, G.M., Villegas Perez, M.P., Thanos, S., and Aguayo, A.J. (1987). Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J. Neurosci. 7, 2894-2909.
37. Woolf, C.J., Shortland, P., Reynolds, M.L., Ridings, J., Doubell, T.P., and Coggeshall, R.E. (1995). Central regenerative sprouting: The reorganization of the central terminals of myelinated primary afferents in the rat dorsal horn following peripheral nerve section or crush. J. Comp. Neurol. 360, 121-134.
38. Wright, D.E., and Snider, W.D. (1995). Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia. J. Comp. Neurol. 357, 329-338.
39. Xu, X.M., Guenard, V., Kleitman, N., Aebischer, P., and Bunge, M.B. (1995). A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Exp. Neurol. 134, 261-272.
40. Zhang, Y., Campbell, G., Anderson, P.N., Lieberman, A.R., Martini, R., and Shachner, M. (1995). The molecular basis of interactions between regenerating adult rat thalamic axons and Schwann cells in peripheral nerve grafts. 1. Neural cell adhesion molecules. J. Comp. Neurol. 361, 193-209.