메뉴 건너뛰기




Volumn 209, Issue 2, 2008, Pages 321-332

The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury

Author keywords

Axon; Cyclic AMP; MAG; Myelin; Regeneration; Rolipram; Spinal cord injury

Indexed keywords

ANTIDEPRESSANT AGENT; ARGINASE 1; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EPHRIN B3; INTERLEUKIN 6; MYELIN; MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; NEUROTROPHIN; NOGO 66 RECEPTOR; PERTUSSIS TOXIN; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM;

EID: 38649128184     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2007.06.020     Document Type: Review
Times cited : (251)

References (103)
  • 1
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso D.M., Beattie M.S., and Bresnahan J.C. A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neurotrauma 12 (1995) 1-21
    • (1995) J. Neurotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 3
    • 3042807052 scopus 로고    scopus 로고
    • Cyclic AMP-induced repair of zebrafish spinal circuits
    • Bhatt D.H., Otto S.J., Depoister B., and Fetcho J.R. Cyclic AMP-induced repair of zebrafish spinal circuits. Science 305 (2004) 254-258
    • (2004) Science , vol.305 , pp. 254-258
    • Bhatt, D.H.1    Otto, S.J.2    Depoister, B.3    Fetcho, J.R.4
  • 4
    • 0035156362 scopus 로고    scopus 로고
    • Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons
    • Bomze H.M., Bulsara K.R., Iskandar B.J., Caroni P., and Skene J.H. Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons. Nat. Neurosci. 4 (2001) 38-43
    • (2001) Nat. Neurosci. , vol.4 , pp. 38-43
    • Bomze, H.M.1    Bulsara, K.R.2    Iskandar, B.J.3    Caroni, P.4    Skene, J.H.5
  • 5
    • 0028867947 scopus 로고
    • Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors
    • Bregman B.S., Kunkel-Bagden E., Schnell L., Dai H.N., Gao D., and Schwab M.E. Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature 378 (1995) 498-501
    • (1995) Nature , vol.378 , pp. 498-501
    • Bregman, B.S.1    Kunkel-Bagden, E.2    Schnell, L.3    Dai, H.N.4    Gao, D.5    Schwab, M.E.6
  • 6
    • 0028866623 scopus 로고
    • Evolution of neuropathologic abnormalities associated with blood-brain barrier breakdown in transgenic mice expressing interleukin-6 in astrocytes
    • Brett F.M., Mizisin A.P., Powell H.C., and Campbell I.L. Evolution of neuropathologic abnormalities associated with blood-brain barrier breakdown in transgenic mice expressing interleukin-6 in astrocytes. J. Neuropathol. Exp. Neurol. 54 (1995) 766-775
    • (1995) J. Neuropathol. Exp. Neurol. , vol.54 , pp. 766-775
    • Brett, F.M.1    Mizisin, A.P.2    Powell, H.C.3    Campbell, I.L.4
  • 7
    • 16944364893 scopus 로고    scopus 로고
    • Targeted overexpression of the neurite growth-associated protein B-50/GAP-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants
    • Buffo A., Holtmaat A.J., Savio T., Verbeek J.S., Oberdick J., Oestreicher A.B., Gispen W.H., Verhaagen J., Rossi F., and Strata P. Targeted overexpression of the neurite growth-associated protein B-50/GAP-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants. J. Neurosci. 17 (1997) 8778-8791
    • (1997) J. Neurosci. , vol.17 , pp. 8778-8791
    • Buffo, A.1    Holtmaat, A.J.2    Savio, T.3    Verbeek, J.S.4    Oberdick, J.5    Oestreicher, A.B.6    Gispen, W.H.7    Verhaagen, J.8    Rossi, F.9    Strata, P.10
  • 8
    • 2342493315 scopus 로고    scopus 로고
    • Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice
    • Cafferty W.B., Gardiner N.J., Das P., Qiu J., McMahon S.B., and Thompson S.W. Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice. J. Neurosci. 24 (2004) 4432-4443
    • (2004) J. Neurosci. , vol.24 , pp. 4432-4443
    • Cafferty, W.B.1    Gardiner, N.J.2    Das, P.3    Qiu, J.4    McMahon, S.B.5    Thompson, S.W.6
  • 9
    • 0032960457 scopus 로고    scopus 로고
    • Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism
    • Cai D., Shen Y., De Bellard M., Tang S., and Filbin M.T. Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism. Neuron 22 (1999) 89-101
    • (1999) Neuron , vol.22 , pp. 89-101
    • Cai, D.1    Shen, Y.2    De Bellard, M.3    Tang, S.4    Filbin, M.T.5
  • 10
    • 0035399823 scopus 로고    scopus 로고
    • Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate
    • Cai D., Qiu J., Cao Z., McAtee M., Bregman B.S., and Filbin M.T. Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate. J. Neurosci. 21 (2001) 4731-4739
    • (2001) J. Neurosci. , vol.21 , pp. 4731-4739
    • Cai, D.1    Qiu, J.2    Cao, Z.3    McAtee, M.4    Bregman, B.S.5    Filbin, M.T.6
  • 11
    • 0037104645 scopus 로고    scopus 로고
    • Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro
    • Cai D., Deng K., Mellado W., Lee J., Ratan R.R., and Filbin M.T. Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro. Neuron 35 (2002) 711-719
    • (2002) Neuron , vol.35 , pp. 711-719
    • Cai, D.1    Deng, K.2    Mellado, W.3    Lee, J.4    Ratan, R.R.5    Filbin, M.T.6
  • 14
    • 0023896592 scopus 로고
    • Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading
    • Caroni P., and Schwab M.E. Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading. J. Cell Biol. 106 (1988) 1281-1288
    • (1988) J. Cell Biol. , vol.106 , pp. 1281-1288
    • Caroni, P.1    Schwab, M.E.2
  • 15
    • 0023967246 scopus 로고
    • Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter
    • Caroni P., and Schwab M.E. Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron 1 (1988) 85-96
    • (1988) Neuron , vol.1 , pp. 85-96
    • Caroni, P.1    Schwab, M.E.2
  • 17
    • 0028598750 scopus 로고
    • Reactive gliosis as a consequence of interleukin-6 expression in the brain: studies in transgenic mice
    • Chiang C., Stalder A., Samimi A., and Campbell I.L. Reactive gliosis as a consequence of interleukin-6 expression in the brain: studies in transgenic mice. Dev. Neurosci. 16 (1994) 212-221
    • (1994) Dev. Neurosci. , vol.16 , pp. 212-221
    • Chiang, C.1    Stalder, A.2    Samimi, A.3    Campbell, I.L.4
  • 18
    • 0030003895 scopus 로고    scopus 로고
    • Intrinsic versus extrinsic factors in determining the regeneration of the central processes of rat dorsal root ganglion neurons: the influence of a peripheral nerve graft
    • Chong M.S., Woolf C.J., Turmaine M., Emson P.C., and Anderson P.N. Intrinsic versus extrinsic factors in determining the regeneration of the central processes of rat dorsal root ganglion neurons: the influence of a peripheral nerve graft. J. Comp. Neurol. 370 (1996) 97-104
    • (1996) J. Comp. Neurol. , vol.370 , pp. 97-104
    • Chong, M.S.1    Woolf, C.J.2    Turmaine, M.3    Emson, P.C.4    Anderson, P.N.5
  • 19
    • 0029993455 scopus 로고    scopus 로고
    • Myelin-associated glycoprotein inhibits axonal regeneration from a variety of neurons via interaction with a sialoglycoprotein
    • De Bellard M.E., Tang S., Mukhopadhyay G., Shen Y.J., and Filbin M.T. Myelin-associated glycoprotein inhibits axonal regeneration from a variety of neurons via interaction with a sialoglycoprotein. Mol. Cell. Neurosci. 7 (1996) 89-101
    • (1996) Mol. Cell. Neurosci. , vol.7 , pp. 89-101
    • De Bellard, M.E.1    Tang, S.2    Mukhopadhyay, G.3    Shen, Y.J.4    Filbin, M.T.5
  • 22
    • 20444365447 scopus 로고    scopus 로고
    • MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth
    • Domeniconi M., Zampieri N., Spencer T., Hilaire M., Mellado W., Chao M.V., and Filbin M.T. MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth. Neuron 46 (2005) 849-855
    • (2005) Neuron , vol.46 , pp. 849-855
    • Domeniconi, M.1    Zampieri, N.2    Spencer, T.3    Hilaire, M.4    Mellado, W.5    Chao, M.V.6    Filbin, M.T.7
  • 23
    • 0035905799 scopus 로고    scopus 로고
    • Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration
    • Fournier A.E., GrandPre T., and Strittmatter S.M. Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature 409 (2001) 341-346
    • (2001) Nature , vol.409 , pp. 341-346
    • Fournier, A.E.1    GrandPre, T.2    Strittmatter, S.M.3
  • 24
    • 0037443069 scopus 로고    scopus 로고
    • Rho kinase inhibition enhances axonal regeneration in the injured CNS
    • Fournier A.E., Takizawa B.T., and Strittmatter S.M. Rho kinase inhibition enhances axonal regeneration in the injured CNS. J. Neurosci. 23 (2003) 1416-1423
    • (2003) J. Neurosci. , vol.23 , pp. 1416-1423
    • Fournier, A.E.1    Takizawa, B.T.2    Strittmatter, S.M.3
  • 25
    • 0028923245 scopus 로고
    • Crucial role for the myelin-associated glycoprotein in the maintenance of axon-myelin integrity
    • Fruttiger M., Montag D., Schachner M., and Martini R. Crucial role for the myelin-associated glycoprotein in the maintenance of axon-myelin integrity. Eur. J. Neurosci. 7 (1995) 511-515
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 511-515
    • Fruttiger, M.1    Montag, D.2    Schachner, M.3    Martini, R.4
  • 26
    • 33847162723 scopus 로고    scopus 로고
    • A role for Nogo receptor in macrophage clearance from injured peripheral nerve
    • Fry E.J., Ho C., and David S. A role for Nogo receptor in macrophage clearance from injured peripheral nerve. Neuron 53 (2007) 649-662
    • (2007) Neuron , vol.53 , pp. 649-662
    • Fry, E.J.1    Ho, C.2    David, S.3
  • 27
    • 0030964023 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6)-a molecule with both beneficial and destructive potentials
    • Gadient R.A., and Otten U.H. Interleukin-6 (IL-6)-a molecule with both beneficial and destructive potentials. Prog. Neurobiol. 52 (1997) 379-390
    • (1997) Prog. Neurobiol. , vol.52 , pp. 379-390
    • Gadient, R.A.1    Otten, U.H.2
  • 28
    • 0347694856 scopus 로고    scopus 로고
    • Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase
    • Gao Y., Nikulina E., Mellado W., and Filbin M.T. Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase. J. Neurosci. 23 (2003) 11770-11777
    • (2003) J. Neurosci. , vol.23 , pp. 11770-11777
    • Gao, Y.1    Nikulina, E.2    Mellado, W.3    Filbin, M.T.4
  • 30
    • 0034719371 scopus 로고    scopus 로고
    • Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein
    • GrandPre T., Nakamura F., Vartanian T., and Strittmatter S.M. Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein. Nature 403 (2000) 439-444
    • (2000) Nature , vol.403 , pp. 439-444
    • GrandPre, T.1    Nakamura, F.2    Vartanian, T.3    Strittmatter, S.M.4
  • 31
    • 0031408944 scopus 로고    scopus 로고
    • Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells
    • Grill R.J., Blesch A., and Tuszynski M.H. Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells. Exp. Neurol. 148 (1997) 444-452
    • (1997) Exp. Neurol. , vol.148 , pp. 444-452
    • Grill, R.J.1    Blesch, A.2    Tuszynski, M.H.3
  • 33
  • 34
    • 10444267294 scopus 로고    scopus 로고
    • Calcium mediates bidirectional growth cone turning induced by myelin-associated glycoprotein
    • Henley J.R., Huang K.H., Wang D., and Poo M.M. Calcium mediates bidirectional growth cone turning induced by myelin-associated glycoprotein. Neuron 44 (2004) 909-916
    • (2004) Neuron , vol.44 , pp. 909-916
    • Henley, J.R.1    Huang, K.H.2    Wang, D.3    Poo, M.M.4
  • 35
    • 0029894833 scopus 로고    scopus 로고
    • Accelerated nerve regeneration in mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma
    • Hirohata H., Kiyama H., Kishimoto T., and Taga T. Accelerated nerve regeneration in mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma. J. Exp. Med. 183 (1996) 2627-2634
    • (1996) J. Exp. Med. , vol.183 , pp. 2627-2634
    • Hirohata, H.1    Kiyama, H.2    Kishimoto, T.3    Taga, T.4
  • 37
    • 0021861426 scopus 로고
    • Clinical effects of the neurotrophic selective cAMP phosphodiesterase inhibitor rolipram in depressed patients: global evaluation of the preliminary reports
    • Horowski R., and Sastre y Hernandez M. Clinical effects of the neurotrophic selective cAMP phosphodiesterase inhibitor rolipram in depressed patients: global evaluation of the preliminary reports. Curr. Ther. Res. 38 (1985) 23-29
    • (1985) Curr. Ther. Res. , vol.38 , pp. 23-29
    • Horowski, R.1    Sastre y Hernandez, M.2
  • 39
    • 0037738758 scopus 로고    scopus 로고
    • Methylprednisolone for acute spinal cord injury: not a standard of care
    • Hugenholtz H. Methylprednisolone for acute spinal cord injury: not a standard of care. CMAJ 168 (2003) 1145-1146
    • (2003) CMAJ , vol.168 , pp. 1145-1146
    • Hugenholtz, H.1
  • 40
    • 0342647473 scopus 로고    scopus 로고
    • Methylprednisolone for acute spinal cord injury: an inappropriate standard of care
    • Hurlbert R.J. Methylprednisolone for acute spinal cord injury: an inappropriate standard of care. J. Neurosurg. 93 (2000) 1-7
    • (2000) J. Neurosurg. , vol.93 , pp. 1-7
    • Hurlbert, R.J.1
  • 41
    • 0031939478 scopus 로고    scopus 로고
    • Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brain
    • Iona S., Cuomo M., Bushnik T., Naro F., Sette C., Hess M., Shelton E.R., and Conti M. Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brain. Mol. Pharmacol. 53 (1998) 23-32
    • (1998) Mol. Pharmacol. , vol.53 , pp. 23-32
    • Iona, S.1    Cuomo, M.2    Bushnik, T.3    Naro, F.4    Sette, C.5    Hess, M.6    Shelton, E.R.7    Conti, M.8
  • 43
    • 0036550340 scopus 로고    scopus 로고
    • NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors
    • Jones L.L., Yamaguchi Y., Stallcup W.B., and Tuszynski M.H. NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. J. Neurosci. 22 (2002) 2792-2803
    • (2002) J. Neurosci. , vol.22 , pp. 2792-2803
    • Jones, L.L.1    Yamaguchi, Y.2    Stallcup, W.B.3    Tuszynski, M.H.4
  • 44
    • 0042665641 scopus 로고    scopus 로고
    • The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan and versican are differentially regulated following spinal cord injury
    • Jones L.L., Margolis R.U., and Tuszynski M.H. The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan and versican are differentially regulated following spinal cord injury. Exp. Neurol. 182 (2003) 399-411
    • (2003) Exp. Neurol. , vol.182 , pp. 399-411
    • Jones, L.L.1    Margolis, R.U.2    Tuszynski, M.H.3
  • 45
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan D.R., and Miller F.D. Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10 (2000) 381-391
    • (2000) Curr. Opin. Neurobiol. , vol.10 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 47
    • 0021270462 scopus 로고
    • Forskolin activation of adenylate cyclase in vivo stimulates nerve regeneration
    • Kilmer S.L., and Carlsen R.C. Forskolin activation of adenylate cyclase in vivo stimulates nerve regeneration. Nature 307 (1984) 455-457
    • (1984) Nature , vol.307 , pp. 455-457
    • Kilmer, S.L.1    Carlsen, R.C.2
  • 48
    • 0031467240 scopus 로고    scopus 로고
    • BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration
    • Kobayashi N.R., Fan D.P., Giehl K.M., Bedard A.M., Wiegand S.J., and Tetzlaff W. BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration. J. Neurosci. 17 (1997) 9583-9595
    • (1997) J. Neurosci. , vol.17 , pp. 9583-9595
    • Kobayashi, N.R.1    Fan, D.P.2    Giehl, K.M.3    Bedard, A.M.4    Wiegand, S.J.5    Tetzlaff, W.6
  • 50
    • 0023935749 scopus 로고
    • Pharmacokinetics of rolipram in the rhesus and cynomolgus monkeys, the rat and the rabbit. Studies on species differences
    • Krause W., and Kuhne G. Pharmacokinetics of rolipram in the rhesus and cynomolgus monkeys, the rat and the rabbit. Studies on species differences. Xenobiotica 18 (1988) 561-571
    • (1988) Xenobiotica , vol.18 , pp. 561-571
    • Krause, W.1    Kuhne, G.2
  • 51
    • 4744367467 scopus 로고    scopus 로고
    • Novel roles for arginase in cell survival, regeneration, and translation in the central nervous system
    • Lange P.S., Langley B., Lu P., and Ratan R.R. Novel roles for arginase in cell survival, regeneration, and translation in the central nervous system. J. Nutr. 134 (2004) 2812S-2817S
    • (2004) J. Nutr. , vol.134
    • Lange, P.S.1    Langley, B.2    Lu, P.3    Ratan, R.R.4
  • 54
    • 0037119581 scopus 로고    scopus 로고
    • Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor
    • Liu B.P., Fournier A., GrandPre T., and Strittmatter S.M. Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor. Science 297 (2002) 1190-1193
    • (2002) Science , vol.297 , pp. 1190-1193
    • Liu, B.P.1    Fournier, A.2    GrandPre, T.3    Strittmatter, S.M.4
  • 55
    • 0037101970 scopus 로고    scopus 로고
    • Function and regulation of CREB family transcription factors in the nervous system
    • Lonze B.E., and Ginty D.D. Function and regulation of CREB family transcription factors in the nervous system. Neuron 35 (2002) 605-623
    • (2002) Neuron , vol.35 , pp. 605-623
    • Lonze, B.E.1    Ginty, D.D.2
  • 56
    • 3242711266 scopus 로고    scopus 로고
    • Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury
    • Lu P., Yang H., Jones L.L., Filbin M.T., and Tuszynski M.H. Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury. J. Neurosci. 24 (2004) 6402-6409
    • (2004) J. Neurosci. , vol.24 , pp. 6402-6409
    • Lu, P.1    Yang, H.2    Jones, L.L.3    Filbin, M.T.4    Tuszynski, M.H.5
  • 57
    • 11844273931 scopus 로고    scopus 로고
    • BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury
    • Lu P., Jones L.L., and Tuszynski M.H. BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury. Exp. Neurol. 191 (2005) 344-360
    • (2005) Exp. Neurol. , vol.191 , pp. 344-360
    • Lu, P.1    Jones, L.L.2    Tuszynski, M.H.3
  • 58
    • 0022976359 scopus 로고
    • Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve
    • Martini R., and Schachner M. Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve. J. Cell Biol. 103 (1986) 2439-2448
    • (1986) J. Cell Biol. , vol.103 , pp. 2439-2448
    • Martini, R.1    Schachner, M.2
  • 59
    • 0025720059 scopus 로고
    • Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes
    • McKeon R.J., Schreiber R.C., Rudge J.S., and Silver J. Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes. J. Neurosci. 11 (1991) 3398-3411
    • (1991) J. Neurosci. , vol.11 , pp. 3398-3411
    • McKeon, R.J.1    Schreiber, R.C.2    Rudge, J.S.3    Silver, J.4
  • 60
    • 0028075680 scopus 로고
    • Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth
    • McKerracher L., David S., Jackson D.L., Kottis V., Dunn R.J., and Braun P.E. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron 13 (1994) 805-811
    • (1994) Neuron , vol.13 , pp. 805-811
    • McKerracher, L.1    David, S.2    Jackson, D.L.3    Kottis, V.4    Dunn, R.J.5    Braun, P.E.6
  • 62
    • 0023890612 scopus 로고
    • A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes
    • Mikol D.D., and Stefansson K. A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes. J. Cell Biol. 106 (1988) 1273-1279
    • (1988) J. Cell Biol. , vol.106 , pp. 1273-1279
    • Mikol, D.D.1    Stefansson, K.2
  • 63
    • 0025089896 scopus 로고
    • The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate
    • Mikol D.D., Gulcher J.R., and Stefansson K. The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate. J. Cell Biol. 110 (1990) 471-479
    • (1990) J. Cell Biol. , vol.110 , pp. 471-479
    • Mikol, D.D.1    Gulcher, J.R.2    Stefansson, K.3
  • 65
    • 0037329897 scopus 로고    scopus 로고
    • Macrophage response to peripheral nerve injury: the quantitative contribution of resident and hematogenous macrophages
    • Mueller M., Leonhard C., Wacker K., Ringelstein E.B., Okabe M., Hickey W.F., and Kiefer R. Macrophage response to peripheral nerve injury: the quantitative contribution of resident and hematogenous macrophages. Lab. Invest. 83 (2003) 175-185
    • (2003) Lab. Invest. , vol.83 , pp. 175-185
    • Mueller, M.1    Leonhard, C.2    Wacker, K.3    Ringelstein, E.B.4    Okabe, M.5    Hickey, W.F.6    Kiefer, R.7
  • 66
    • 0028060651 scopus 로고
    • A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration
    • Mukhopadhyay G., Doherty P., Walsh F.S., Crocker P.R., and Filbin M.T. A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration. Neuron 13 (1994) 757-767
    • (1994) Neuron , vol.13 , pp. 757-767
    • Mukhopadhyay, G.1    Doherty, P.2    Walsh, F.S.3    Crocker, P.R.4    Filbin, M.T.5
  • 67
    • 0033137077 scopus 로고    scopus 로고
    • Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury
    • Neumann S., and Woolf C.J. Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury. Neuron 23 (1999) 83-91
    • (1999) Neuron , vol.23 , pp. 83-91
    • Neumann, S.1    Woolf, C.J.2
  • 68
    • 0037071890 scopus 로고    scopus 로고
    • Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation
    • Neumann S., Bradke F., Tessier-Lavigne M., and Basbaum A.I. Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron 34 (2002) 885-893
    • (2002) Neuron , vol.34 , pp. 885-893
    • Neumann, S.1    Bradke, F.2    Tessier-Lavigne, M.3    Basbaum, A.I.4
  • 69
    • 2942558484 scopus 로고    scopus 로고
    • The phosphodiesterase inhibitor rolipram delivered after a spinal cord lesion promotes axonal regeneration and functional recovery
    • Nikulina E., Tidwell J.L., Dai H.N., Bregman B.S., and Filbin M.T. The phosphodiesterase inhibitor rolipram delivered after a spinal cord lesion promotes axonal regeneration and functional recovery. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 8786-8790
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 8786-8790
    • Nikulina, E.1    Tidwell, J.L.2    Dai, H.N.3    Bregman, B.S.4    Filbin, M.T.5
  • 70
    • 0028171971 scopus 로고
    • Regeneration of adult rat sensory axons into intraspinal nerve grafts: promoting effects of conditioning lesion and graft predegeneration
    • Oudega M., Varon S., and Hagg T. Regeneration of adult rat sensory axons into intraspinal nerve grafts: promoting effects of conditioning lesion and graft predegeneration. Exp. Neurol. 129 (1994) 194-206
    • (1994) Exp. Neurol. , vol.129 , pp. 194-206
    • Oudega, M.1    Varon, S.2    Hagg, T.3
  • 71
    • 0024488583 scopus 로고
    • Evidence for an early role for myelin-associated glycoprotein in the process of myelination
    • Owens G.C., and Bunge R.P. Evidence for an early role for myelin-associated glycoprotein in the process of myelination. Glia 2 (1989) 119-128
    • (1989) Glia , vol.2 , pp. 119-128
    • Owens, G.C.1    Bunge, R.P.2
  • 72
    • 13244255374 scopus 로고    scopus 로고
    • A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors
    • Park J.B., Yiu G., Kaneko S., Wang J., Chang J., He X.L., Garcia K.C., and He Z. A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors. Neuron 45 (2005) 345-351
    • (2005) Neuron , vol.45 , pp. 345-351
    • Park, J.B.1    Yiu, G.2    Kaneko, S.3    Wang, J.4    Chang, J.5    He, X.L.6    Garcia, K.C.7    He, Z.8
  • 76
    • 0021220983 scopus 로고
    • Peripheral injury enhances central regeneration of primary sensory neurones
    • Richardson P.M., and Issa V.M. Peripheral injury enhances central regeneration of primary sensory neurones. Nature 309 (1984) 791-793
    • (1984) Nature , vol.309 , pp. 791-793
    • Richardson, P.M.1    Issa, V.M.2
  • 77
    • 0036344505 scopus 로고    scopus 로고
    • Neurotrophin signaling through the p75 neurotrophin receptor
    • Roux P.P., and Barker P.A. Neurotrophin signaling through the p75 neurotrophin receptor. Prog. Neurobiol. 67 (2002) 203-233
    • (2002) Prog. Neurobiol. , vol.67 , pp. 203-233
    • Roux, P.P.1    Barker, P.A.2
  • 78
    • 0023198136 scopus 로고
    • The amino acid sequences of the myelin-associated glycoproteins: homology to the immunoglobulin gene superfamily
    • Salzer J.L., Holmes W.P., and Colman D.R. The amino acid sequences of the myelin-associated glycoproteins: homology to the immunoglobulin gene superfamily. J. Cell Biol. 104 (1987) 957-965
    • (1987) J. Cell Biol. , vol.104 , pp. 957-965
    • Salzer, J.L.1    Holmes, W.P.2    Colman, D.R.3
  • 80
    • 0025017637 scopus 로고
    • Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors
    • Schnell L., and Schwab M.E. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature 343 (1990) 269-272
    • (1990) Nature , vol.343 , pp. 269-272
    • Schnell, L.1    Schwab, M.E.2
  • 81
    • 0027213847 scopus 로고
    • Sprouting and regeneration of lesioned corticospinal tract fibres in the adult rat spinal cord
    • Schnell L., and Schwab M.E. Sprouting and regeneration of lesioned corticospinal tract fibres in the adult rat spinal cord. Eur. J. Neurosci. 5 (1993) 1156-1171
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 1156-1171
    • Schnell, L.1    Schwab, M.E.2
  • 82
    • 0028115777 scopus 로고
    • Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion
    • Schnell L., Schneider R., Kolbeck R., Barde Y.A., and Schwab M.E. Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature 367 (1994) 170-173
    • (1994) Nature , vol.367 , pp. 170-173
    • Schnell, L.1    Schneider, R.2    Kolbeck, R.3    Barde, Y.A.4    Schwab, M.E.5
  • 83
    • 0027232466 scopus 로고
    • Injury-associated induction of GAP-43 expression displays axon branch specificity in rat dorsal root ganglion neurons
    • Schreyer D.J., and Skene J.H. Injury-associated induction of GAP-43 expression displays axon branch specificity in rat dorsal root ganglion neurons. J. Neurobiol. 24 (1993) 959-970
    • (1993) J. Neurobiol. , vol.24 , pp. 959-970
    • Schreyer, D.J.1    Skene, J.H.2
  • 84
    • 33745001188 scopus 로고    scopus 로고
    • The transcription factor ATF-3 promotes neurite outgrowth
    • Seijffers R., Allchorne A.J., and Woolf C.J. The transcription factor ATF-3 promotes neurite outgrowth. Mol. Cell. Neurosci. 32 (2006) 143-154
    • (2006) Mol. Cell. Neurosci. , vol.32 , pp. 143-154
    • Seijffers, R.1    Allchorne, A.J.2    Woolf, C.J.3
  • 86
    • 0035684665 scopus 로고    scopus 로고
    • Is the role of steroids in acute spinal cord injury now resolved?
    • Short D. Is the role of steroids in acute spinal cord injury now resolved?. Curr. Opin. Neurol. 14 (2001) 759-763
    • (2001) Curr. Opin. Neurol. , vol.14 , pp. 759-763
    • Short, D.1
  • 87
    • 0742288565 scopus 로고    scopus 로고
    • Regeneration beyond the glial scar
    • Silver J., and Miller J.H. Regeneration beyond the glial scar. Nat. Rev., Neurosci. 5 (2004) 146-156
    • (2004) Nat. Rev., Neurosci. , vol.5 , pp. 146-156
    • Silver, J.1    Miller, J.H.2
  • 88
    • 1442299897 scopus 로고    scopus 로고
    • PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration
    • Sivasankaran R., Pei J., Wang K.C., Zhang Y.P., Shields C.B., Xu X.M., and He Z. PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration. Nat. Neurosci. 7 (2004) 261-268
    • (2004) Nat. Neurosci. , vol.7 , pp. 261-268
    • Sivasankaran, R.1    Pei, J.2    Wang, K.C.3    Zhang, Y.P.4    Shields, C.B.5    Xu, X.M.6    He, Z.7
  • 89
    • 0032483342 scopus 로고    scopus 로고
    • Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides
    • Song H., Ming G., He Z., Lehmann M., McKerracher L., Tessier-Lavigne M., and Poo M. Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides. Science 281 (1998) 1515-1518
    • (1998) Science , vol.281 , pp. 1515-1518
    • Song, H.1    Ming, G.2    He, Z.3    Lehmann, M.4    McKerracher, L.5    Tessier-Lavigne, M.6    Poo, M.7
  • 90
    • 14444268726 scopus 로고    scopus 로고
    • Myelin-associated glycoprotein interacts with neurons via a sialic acid binding site at ARG118 and a distinct neurite inhibition site
    • Tang S., Shen Y.J., DeBellard M.E., Mukhopadhyay G., Salzer J.L., Crocker P.R., and Filbin M.T. Myelin-associated glycoprotein interacts with neurons via a sialic acid binding site at ARG118 and a distinct neurite inhibition site. J. Cell Biol. 138 (1997) 1355-1366
    • (1997) J. Cell Biol. , vol.138 , pp. 1355-1366
    • Tang, S.1    Shen, Y.J.2    DeBellard, M.E.3    Mukhopadhyay, G.4    Salzer, J.L.5    Crocker, P.R.6    Filbin, M.T.7
  • 91
    • 0037310986 scopus 로고    scopus 로고
    • Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue
    • Tang X., Davies J.E., and Davies S.J. Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue. J. Neurosci. Res. 71 (2003) 427-444
    • (2003) J. Neurosci. Res. , vol.71 , pp. 427-444
    • Tang, X.1    Davies, J.E.2    Davies, S.J.3
  • 92
    • 0345227300 scopus 로고    scopus 로고
    • Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration
    • Tobias C.A., Shumsky J.S., Shibata M., Tuszynski M.H., Fischer I., Tessler A., and Murray M. Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration. Exp. Neurol. 184 (2003) 97-113
    • (2003) Exp. Neurol. , vol.184 , pp. 97-113
    • Tobias, C.A.1    Shumsky, J.S.2    Shibata, M.3    Tuszynski, M.H.4    Fischer, I.5    Tessler, A.6    Murray, M.7
  • 93
    • 0032557845 scopus 로고    scopus 로고
    • MAG and MOG enhance neurite outgrowth of embryonic mouse spinal cord neurons
    • Turnley A.M., and Bartlett P.F. MAG and MOG enhance neurite outgrowth of embryonic mouse spinal cord neurons. NeuroReport 9 (1998) 1987-1990
    • (1998) NeuroReport , vol.9 , pp. 1987-1990
    • Turnley, A.M.1    Bartlett, P.F.2
  • 94
    • 0037403572 scopus 로고    scopus 로고
    • NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection
    • Tuszynski M.H., Grill R., Jones L.L., Brant A., Blesch A., Low K., Lacroix S., and Lu P. NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection. Exp. Neurol. 181 (2003) 47-56
    • (2003) Exp. Neurol. , vol.181 , pp. 47-56
    • Tuszynski, M.H.1    Grill, R.2    Jones, L.L.3    Brant, A.4    Blesch, A.5    Low, K.6    Lacroix, S.7    Lu, P.8
  • 96
    • 0037182860 scopus 로고    scopus 로고
    • Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth
    • Wang K.C., Koprivica V., Kim J.A., Sivasankaran R., Guo Y., Neve R.L., and He Z. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature 417 (2002) 941-944
    • (2002) Nature , vol.417 , pp. 941-944
    • Wang, K.C.1    Koprivica, V.2    Kim, J.A.3    Sivasankaran, R.4    Guo, Y.5    Neve, R.L.6    He, Z.7
  • 97
    • 0037038435 scopus 로고    scopus 로고
    • P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp
    • Wang K.C., Kim J.A., Sivasankaran R., Segal R., and He Z. P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp. Nature 420 (2002) 74-78
    • (2002) Nature , vol.420 , pp. 74-78
    • Wang, K.C.1    Kim, J.A.2    Sivasankaran, R.3    Segal, R.4    He, Z.5
  • 98
    • 0036897583 scopus 로고    scopus 로고
    • A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein
    • Wong S.T., Henley J.R., Kanning K.C., Huang K.H., Bothwell M., and Poo M.M. A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein. Nat. Neurosci. 5 (2002) 1302-1308
    • (2002) Nat. Neurosci. , vol.5 , pp. 1302-1308
    • Wong, S.T.1    Henley, J.R.2    Kanning, K.C.3    Huang, K.H.4    Bothwell, M.5    Poo, M.M.6
  • 99
    • 0033230625 scopus 로고    scopus 로고
    • Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth
    • Yamashita T., Tucker K.L., and Barde Y.A. Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth. Neuron 24 (1999) 585-593
    • (1999) Neuron , vol.24 , pp. 585-593
    • Yamashita, T.1    Tucker, K.L.2    Barde, Y.A.3
  • 100
    • 0037408391 scopus 로고    scopus 로고
    • The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI
    • Yamashita T., and Tohyama M. The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat. Neurosci. 6 (2003) 461-467
    • (2003) Nat. Neurosci. , vol.6 , pp. 461-467
    • Yamashita, T.1    Tohyama, M.2
  • 101
    • 0037071537 scopus 로고    scopus 로고
    • The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho
    • Yamashita T., Higuchi H., and Tohyama M. The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho. J. Cell Biol. 157 (2002) 565-570
    • (2002) J. Cell Biol. , vol.157 , pp. 565-570
    • Yamashita, T.1    Higuchi, H.2    Tohyama, M.3
  • 102
    • 0035132793 scopus 로고    scopus 로고
    • Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline
    • Yokoyama N., Romero M.I., Cowan C.A., Galvan P., Helmbacher F., Charnay P., Parada L.F., and Henkemeyer M. Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline. Neuron 29 (2001) 85-97
    • (2001) Neuron , vol.29 , pp. 85-97
    • Yokoyama, N.1    Romero, M.I.2    Cowan, C.A.3    Galvan, P.4    Helmbacher, F.5    Charnay, P.6    Parada, L.F.7    Henkemeyer, M.8
  • 103
    • 34249712685 scopus 로고    scopus 로고
    • PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord
    • Yoshida Y., Han B., Mendelsohn M., and Jessell T.M. PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Neuron 52 (2006) 775-788
    • (2006) Neuron , vol.52 , pp. 775-788
    • Yoshida, Y.1    Han, B.2    Mendelsohn, M.3    Jessell, T.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.