-
1
-
-
75749100093
-
Mutational heterogeneity in human cancers: Origin and consequences
-
Salk, J., Fox, E. and Loeb, L. (2010) Mutational heterogeneity in human cancers: origin and consequences. Annu. Rev. Pathol., 5, 51-75.
-
(2010)
Annu. Rev. Pathol.
, vol.5
, pp. 51-75
-
-
Salk, J.1
Fox, E.2
Loeb, L.3
-
2
-
-
0037342752
-
Somatic gene mutation and human disease other than cancer
-
DOI 10.1016/S1383-5742(03)00010-3
-
Erickson, R. (2003) Somatic gene mutation and human disease other than cancer. Mutat. Res., 543, 125-136. (Pubitemid 36329167)
-
(2003)
Mutation Research - Reviews in Mutation Research
, vol.543
, Issue.2
, pp. 125-136
-
-
Erickson, R.P.1
-
3
-
-
0017233053
-
The use of correction factors in the determination of mutant frequencies in populations of human diploid skin fibroblasts
-
van Zeeland, A. and Simons, J. (1976) The use of correction factors in the determination of mutant frequencies in populations of human diploid skin fibroblasts. Mutat. Res., 34, 149-158.
-
(1976)
Mutat. Res.
, vol.34
, pp. 149-158
-
-
Van Zeeland, A.1
Simons, J.2
-
4
-
-
0023135430
-
Mutation rate of normal and malignant human lymphocytes
-
Seshadri, R., Kutlaca, R., Trainor, K., Matthews, C. and Morley, A. (1987) Mutation rate of normal and malignant human lymphocytes. Cancer Res., 47, 407-409. (Pubitemid 17009600)
-
(1987)
Cancer Research
, vol.47
, Issue.2
, pp. 407-409
-
-
Seshadri, R.1
Kutlaca, R.J.2
Trainor, K.3
-
5
-
-
18744416025
-
Quantification of random genomic mutations
-
DOI 10.1038/nmeth751
-
Bielas, J. and Loeb, L. (2005) Quantification of random genomic mutations. Nat. Methods, 2, 285-290. (Pubitemid 41131010)
-
(2005)
Nature Methods
, vol.2
, Issue.4
, pp. 285-290
-
-
Bielas, J.H.1
Loeb, L.A.2
-
6
-
-
33845311843
-
Human cancers express a mutator phenotype
-
DOI 10.1073/pnas.0607057103
-
Bielas, J., Loeb, K., Rubin, B., True, L. and Loeb, L. (2006) Human cancers express a mutator phenotype. Proc. Natl Acad. Sci. USA, 103, 18238-18242. (Pubitemid 44871642)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.48
, pp. 18238-18242
-
-
Bielas, J.H.1
Loeb, K.R.2
Rubin, B.P.3
True, L.D.4
Loeb, L.A.5
-
7
-
-
0025165632
-
Restriction site mutation analysis, a proposed methodology for the detection and study of DNA base changes following mutagen exposure
-
Parry, J., Shamsher, M. and Skibinski, D. (1990) Restriction site mutation analysis, a proposed methodology for the detection and study of DNA base changes following mutagen exposure. Mutagenesis, 5, 209-212. (Pubitemid 20329936)
-
(1990)
Mutagenesis
, vol.5
, Issue.3
, pp. 209-212
-
-
Parry, J.M.1
Shamsher, M.2
Skibinski, D.O.F.3
-
8
-
-
0026503937
-
Genotypic analysis of mutations in Taq i restriction recognition sites by restriction fragment length polymorphism/polymerase chain reaction
-
Sandy, M., Chiocca, S. and Cerutti, P. (1992) Genotypic analysis of mutations in Taq I restriction recognition sites by restriction fragment length polymorphism/polymerase chain reaction. Proc. Natl Acad. Sci. USA, 89, 890-894.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 890-894
-
-
Sandy, M.1
Chiocca, S.2
Cerutti, P.3
-
9
-
-
0025838289
-
Analysis of spontaneous and induced mutations in transgenic mice using a lambda ZAP/lacI shuttle vector
-
Kohler, S., Provost, G., Fieck, A., Kretz, P., Bullock, W., Putman, D., Sorge, J. and Short, J. (1991) Analysis of spontaneous and induced mutations in transgenic mice using a lambda ZAP/lacI shuttle vector. Environ. Mol. Mutagen., 18, 316-321.
-
(1991)
Environ. Mol. Mutagen.
, vol.18
, pp. 316-321
-
-
Kohler, S.1
Provost, G.2
Fieck, A.3
Kretz, P.4
Bullock, W.5
Putman, D.6
Sorge, J.7
Short, J.8
-
10
-
-
0025779567
-
Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice
-
Kohler, S., Provost, G., Fieck, A., Kretz, P., Bullock, W., Sorge, J., Putman, D. and Short, J. (1991) Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice. Proc. Natl Acad. Sci. USA., 88, 7958-7962. (Pubitemid 21915274)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.18
, pp. 7958-7962
-
-
Kohler, S.W.1
Scott Provost, G.2
Fieck, A.3
Kretz, P.L.4
Bullock, W.O.5
Sorge, J.A.6
Putman, D.L.7
Short, J.M.8
-
11
-
-
0024374202
-
Efficient rescue of integrated shuttle vectors from transgenic mice: A model for studying mutations in vivo
-
Gossen, J., de Leeuw, W., Tan, C., Zwarthoff, E., Berends, F., Lohman, P., Knook, D. and Vijg, J. (1989) Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo. Proc. Natl Acad. Sci. USA, 86, 7971-7975. (Pubitemid 19265301)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.20
, pp. 7971-7975
-
-
Gossen, J.A.1
De Leeuw, W.J.F.2
Tan, C.H.T.3
Zwarthoff, E.C.4
Berends, F.5
Lohman, P.H.M.6
Knook, D.L.7
Vijg, J.8
-
12
-
-
70350126567
-
DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice
-
Albertson, T., Ogawa, M., Bugni, J., Hays, L., Chen, Y., Wang, Y., Treuting, P., Heddle, J., Goldsby, R. and Preston, B. (2009) DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. Proc. Natl Acad. Sci. USA, 106, 17101-17104.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 17101-17104
-
-
Albertson, T.1
Ogawa, M.2
Bugni, J.3
Hays, L.4
Chen, Y.5
Wang, Y.6
Treuting, P.7
Heddle, J.8
Goldsby, R.9
Preston, B.10
-
13
-
-
0024474078
-
A conserved 30-50 exonuclease active site in prokaryotic and eukaryotic DNA polymerases
-
DOI 10.1016/0092-8674(89)90883-0
-
Bernad, A., Blanco, L., Lázaro, J., Martín, G. and Salas, M. (1989) A conserved 30-50 exonuclease active site in prokaryotic and eukaryotic DNA polymerases. Cell, 59, 219-228. (Pubitemid 19248571)
-
(1989)
Cell
, vol.59
, Issue.1
, pp. 219-228
-
-
Bernad, A.1
Blanco, L.2
Lazaro, J.M.3
Martin, G.4
Salas, M.5
-
14
-
-
0025900035
-
The 3' to 5' exonuclease activity located in the DNA polymerase δ subunit of Saccharomyces cerevisiae is required for accurate replication
-
Simon, M., Giot, L. and Faye, G. (1991) The 30 to 50 exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication. EMBO J., 10, 2165-2170. (Pubitemid 21905688)
-
(1991)
EMBO Journal
, vol.10
, Issue.8
, pp. 2165-2170
-
-
Simon, M.1
Giot, L.2
Faye, G.3
-
15
-
-
0028174896
-
The 30->50 exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiae
-
Morrison, A. and Sugino, A. (1994) The 30->50 exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiae. Mol. Gen. Genet., 242, 289-296.
-
(1994)
Mol. Gen. Genet.
, vol.242
, pp. 289-296
-
-
Morrison, A.1
Sugino, A.2
-
16
-
-
0037180555
-
High incidence of epithelial cancers in mice deficient for DNA polymerase δ proofreading
-
DOI 10.1073/pnas.232340999
-
Goldsby, R., Hays, L., Chen, X., Olmsted, E., Slayton, W., Spangrude, G. and Preston, B. (2002) High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading. Proc. Natl Acad. Sci. USA, 99, 15560-15565. (Pubitemid 35403973)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.24
, pp. 15560-15565
-
-
Goldsby, R.E.1
Hays, L.E.2
Chen, X.3
Olmsted, E.A.4
Slayton, W.B.5
Spangrude, G.J.6
Preston, B.D.7
-
17
-
-
0031419013
-
Artificial background and induced levels of oxidative base damage in DNA from human cells
-
DOI 10.1093/carcin/18.11.2281
-
Kvam, E. and Tyrrell, R. (1997) Artificial background and induced levels of oxidative base damage in DNA from human cells. Carcinogenesis, 18, 2281-2283. (Pubitemid 28134760)
-
(1997)
Carcinogenesis
, vol.18
, Issue.11
, pp. 2281-2283
-
-
Kvam, E.1
Tyrrell, R.M.2
-
18
-
-
34447132813
-
Fen1 mutations result in autoimmunity, chronic inflammation and cancers
-
DOI 10.1038/nm1599, PII NM1599
-
Zheng, L., Dai, H., Zhou, M., Li, M., Singh, P., Qiu, J., Tsark, W., Huang, Q., Kernstine, K., Zhang, X. et al. (2007) Fen1 mutations result in autoimmunity, chronic inflammation and cancers. Nat. Med., 13, 812-819. (Pubitemid 47038189)
-
(2007)
Nature Medicine
, vol.13
, Issue.7
, pp. 812-819
-
-
Zheng, L.1
Dai, H.2
Zhou, M.3
Li, M.4
Singh, P.5
Qiu, J.6
Tsark, W.7
Huang, Q.8
Kernstine, K.9
Zhang, X.10
Lin, D.11
Shen, B.12
-
19
-
-
73449083412
-
Stochastic drift in mitochondrial DNA point mutations: A novel perspective ex silico
-
Poovathingal, S., Gruber, J., Halliwell, B. and Gunawan, R. (2009) Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico. PLoS Comput. Biol., 5, e1000572.
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Poovathingal, S.1
Gruber, J.2
Halliwell, B.3
Gunawan, R.4
-
20
-
-
0028217661
-
Comparative analysis of DNA mutations in lacI transgenic mice with age
-
Lee, A., DeSimone, C., Cerami, A. and Bucala, R. (1994) Comparative analysis of DNA mutations in lacI transgenic mice with age. FASEB J., 8, 545-550. (Pubitemid 24161129)
-
(1994)
FASEB Journal
, vol.8
, Issue.8
, pp. 545-550
-
-
Lee, A.T.1
Desimone, C.2
Cerami, A.3
Bucala, R.4
-
21
-
-
0029133856
-
Spontaneous mutant frequency of lacZ gene in spleen of transgenic mouse increases with age
-
Ono, T., Miyamura, Y., Ikehata, H., Yamanaka, H., Kurishita, A., Yamamoto, K., Suzuki, T., Nohmi, T., Hayashi, M. and Sofuni, T. (1995) Spontaneous mutant frequency of lacZ gene in spleen of transgenic mouse increases with age. Mutat. Res., 338, 183-188.
-
(1995)
Mutat. Res.
, vol.338
, pp. 183-188
-
-
Ono, T.1
Miyamura, Y.2
Ikehata, H.3
Yamanaka, H.4
Kurishita, A.5
Yamamoto, K.6
Suzuki, T.7
Nohmi, T.8
Hayashi, M.9
Sofuni, T.10
-
22
-
-
0032511836
-
A comparative study of in vivo mutation assays: Analysis of hprt, lacI, and cII/cI as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue(TM) mice
-
DOI 10.1016/S0027-5107(98)00171-7, PII S0027510798001717
-
Monroe, J., Kort, K., Miller, J., Marino, D. and Skopek, T. (1998) A comparative study of in vivo mutation assays: analysis of hprt, lacI, cII/cI and as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue mice. Mutat. Res., 421, 121-136. (Pubitemid 29039294)
-
(1998)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.421
, Issue.1
, pp. 121-136
-
-
Monroe, J.J.1
Kort, K.L.2
Miller, J.E.3
Marino, D.R.4
Skopek, T.R.5
-
23
-
-
33644836197
-
IMARS - Mutation analysis reporting software: An analysis of spontaneous cII mutation spectra
-
DOI 10.1016/j.mrgentox.2005.09.010, PII S1383571805002561
-
Morgan, C. and Lewis, P. (2006) iMARS-mutation analysis reporting software: an analysis of spontaneous cII mutation spectra. Mutat. Res., 603, 15-26. (Pubitemid 43362744)
-
(2006)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.603
, Issue.1
, pp. 15-26
-
-
Morgan, C.1
Lewis, P.D.2
-
24
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
DOI 10.1126/science.1133427
-
Sjöblom, T., Jones, S., Wood, L., Parsons, D., Lin, J., Barber, T., Mandelker, D., Leary, R., Ptak, J., Silliman, N. et al. (2006) The consensus coding sequences of human breast and colorectal cancers. Science, 314, 268-274. (Pubitemid 44571966)
-
(2006)
Science
, vol.314
, Issue.5797
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
Mandelker, D.7
Leary, R.J.8
Ptak, J.9
Silliman, N.10
Szabo, S.11
Buckhaults, P.12
Farrell, C.13
Meeh, P.14
Markowitz, S.D.15
Willis, J.16
Dawson, D.17
Willson, J.K.V.18
Gazdar, A.F.19
Hartigan, J.20
Wu, L.21
Liu, C.22
Parmigiani, G.23
Park, B.H.24
Bachman, K.E.25
Papadopoulos, N.26
Vogelstein, B.27
Kinzler, K.W.28
Velculescu, V.E.29
more..
-
25
-
-
0029670573
-
30->50 exonucleases of DNA polymerases epsilon and delta correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae
-
Shcherbakova, P. and Pavlov, Y. (1996) 30->50 exonucleases of DNA polymerases epsilon and delta correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae. Genetics, 142, 717-726.
-
(1996)
Genetics
, vol.142
, pp. 717-726
-
-
Shcherbakova, P.1
Pavlov, Y.2
-
26
-
-
23744463885
-
Detailed review of transgenic rodent mutation assays
-
DOI 10.1016/j.mrrev.2005.04.002, PII S1383574205000384
-
Lambert, I., Singer, T., Boucher, S. and Douglas, G. (2005) Detailed review of transgenic rodent mutation assays. Mutat. Res., 590, 1-280. (Pubitemid 41121981)
-
(2005)
Mutation Research - Reviews in Mutation Research
, vol.590
, Issue.1-3
, pp. 1-280
-
-
Lambert, I.B.1
Singer, T.M.2
Boucher, S.E.3
Douglas, G.R.4
-
27
-
-
0032936730
-
Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens
-
DOI 10.1093/mutage/14.1.141
-
Dean, S., Brooks, T., Burlinson, B., Mirsalis, J., Myhr, B., Recio, L. and Thybaud, V. (1999) Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens. Mutagenesis, 14, 141-151. (Pubitemid 29048255)
-
(1999)
Mutagenesis
, vol.14
, Issue.1
, pp. 141-151
-
-
Dean, S.W.1
Brooks, T.M.2
Burlinson, B.3
Mirsalis, J.4
Myhr, B.5
Recio, L.6
Thybaud, V.7
-
28
-
-
33745211644
-
Methods for determining spontaneous mutation rates
-
Foster, P. (2006) Methods for determining spontaneous mutation rates. Methods Enzymol., 409, 195-213.
-
(2006)
Methods Enzymol.
, vol.409
, pp. 195-213
-
-
Foster, P.1
-
29
-
-
2642516979
-
Quiescent murine cells lack global genomic repair but are proficient in transcription-coupled repair
-
DOI 10.1016/j.dnarep.2004.02.010, PII S156878640400059X
-
Bielas, J. and Heddle, J. (2004) Quiescent murine cells lack global genomic repair but are proficient in transcription-coupled repair. DNA Repair (Amst), 3, 711-717. (Pubitemid 38716100)
-
(2004)
DNA Repair
, vol.3
, Issue.7
, pp. 711-717
-
-
Bielas, J.H.1
Heddle, J.A.2
-
30
-
-
56249144518
-
Quantification of random mutations in the mitochondrial genome
-
Vermulst, M., Bielas, J. and Loeb, L. (2008) Quantification of random mutations in the mitochondrial genome. Methods, 46, 263-268.
-
(2008)
Methods
, vol.46
, pp. 263-268
-
-
Vermulst, M.1
Bielas, J.2
Loeb, L.3
|