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Volumn 2, Issue 4, 2013, Pages

Myeloid derived suppressor cells targets for therapy

Author keywords

Cpg oligodeoxynucleotides (ODN); Curcumin; Cyclophosphamide; Docetaxol; Gemcitabine; Myeloid derived suppressor cells; RNA aptamer

Indexed keywords

3,5,7 TRIHYDROXY 4' EMTHOXY 8 (3 HYDROXY 3 METHYLBUTYL)FLAVONE; ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER; ALPHA INTERFERON; ANTINEOPLASTIC AGENT; APTAMER; ARGINASE 1; BETA INTERFERON; CELECOXIB; CPG OLIGODEOXYNUCLEOTIDE; CURCUMIN; CYCLOPHOSPHAMIDE; DENDRITIC CELL VACCINE; DOCETAXEL; FLUOROURACIL; GAMMA INTERFERON; GEMCITABINE; ICARIIN; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 1BETA ANTIBODY; L SELECTIN; MATRIX METALLOPROTEINASE INHIBITOR; PLACEBO; REACTIVE OXYGEN METABOLITE; RETINOIC ACID; SILDENAFIL; TADALAFIL; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84885956883     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/onci.24117     Document Type: Article
Times cited : (66)

References (89)
  • 1
    • 84868030361 scopus 로고    scopus 로고
    • Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer
    • Quatromoni JG, Eruslanov E. Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer. American journal of translational research 2012; 4:376-89
    • (2012) American journal of translational research , vol.4 , pp. 376-389
    • Quatromoni, J.G.1    Eruslanov, E.2
  • 2
    • 23444456772 scopus 로고    scopus 로고
    • Regulation of immune responses by L-arginine metabolism
    • Bronte V, Zanovello P. Regulation of immune responses by L-arginine metabolism. Nat Rev Immunol 2005; 5:641-54; http://dx.doi. org/10.1038/nri1668
    • (2005) Nat Rev Immunol , vol.5 , pp. 641-654
    • Bronte, V.1    Zanovello, P.2
  • 3
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: linking inflammation and cancer
    • Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 2009; 182:4499-506; http://dx.doi.org/10.4049/jimmunol.0802740
    • (2009) J Immunol , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 4
    • 0035164478 scopus 로고    scopus 로고
    • Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer
    • Almand B, Clark JI, Nikitina E, Van Beynen J, English NR, Knight SC, et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 2001; 166:678-89.
    • (2001) J Immunol , vol.166 , pp. 678-689
    • Almand, B.1    Clark, J.I.2    Nikitina, E.3    Van Beynen, J.4    English, N.R.5    Knight, S.C.6
  • 5
    • 54849440346 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
    • Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother 2009; 58:49-59; http://dx.doi.org/10.1007/s00262-008-0523-4
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 49-59
    • Diaz-Montero, C.M.1    Salem, M.L.2    Nishimura, M.I.3    Garrett-Mayer, E.4    Cole, D.J.5    Montero, A.J.6
  • 6
    • 77957991455 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in human cancer.
    • Nagaraj S, Gabrilovich DI. Myeloid-derived suppressor cells in human cancer. Cancer J 2010; 16:348-53; http://dx.doi.org/10.1097/ PPO.0b013e3181eb3358
    • (2010) Cancer J , vol.16 , pp. 348-353
    • Nagaraj, S.1    Gabrilovich, D.I.2
  • 8
    • 5444225991 scopus 로고    scopus 로고
    • Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis
    • Yang L, DeBusk LM, Fukuda K, Fingleton B, Green-Jarvis B, Shyr Y, et al. Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell 2004; 6:409-21; http://dx.doi. org/10.1016/j.ccr.2004.08.031
    • (2004) Cancer Cell , vol.6 , pp. 409-421
    • Yang, L.1    DeBusk, L.M.2    Fukuda, K.3    Fingleton, B.4    Green-Jarvis, B.5    Shyr, Y.6
  • 9
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
    • Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 2011; 331:1565-70; http://dx.doi.org/10.1126/science. 1203486
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 10
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: from immunosurveillance to tumor escape
    • Dunn GP, Bruce AT, Ikeda H, Old LJ, Schreiber RD. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol 2002; 3:991-8; http://dx.doi.org/10.1038/ni1102-991
    • (2002) Nat Immunol , vol.3 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3    Old, L.J.4    Schreiber, R.D.5
  • 11
    • 0035320526 scopus 로고    scopus 로고
    • A fresh look at tumor immunosurveillance and immunotherapy
    • Smyth MJ, Godfrey DI, Trapani JA. A fresh look at tumor immunosurveillance and immunotherapy. Nat Immunol 2001; 2:293-9; http:// dx.doi.org/10.1038/86297
    • (2001) Nat Immunol , vol.2 , pp. 293-299
    • Smyth, M.J.1    Godfrey, D.I.2    Trapani, J.A.3
  • 12
    • 36849010167 scopus 로고    scopus 로고
    • Adaptive immunity maintains occult cancer in an equilibrium state
    • Koebel CM, Vermi W, Swann JB, Zerafa N, Rodig SJ, Old LJ, et al. Adaptive immunity maintains occult cancer in an equilibrium state. Nature 2007; 450:903-7; http://dx.doi.org/10.1038/ nature06309
    • (2007) Nature , vol.450 , pp. 903-907
    • Koebel, C.M.1    Vermi, W.2    Swann, J.B.3    Zerafa, N.4    Rodig, S.J.5    Old, L.J.6
  • 13
    • 84865116628 scopus 로고    scopus 로고
    • Opposing roles for IL-23 and IL-12 in maintaining occult cancer in an equilibrium state
    • Teng MW, Vesely MD, Duret H, McLaughlin N, Towne JE, Schreiber RD, et al. Opposing roles for IL-23 and IL-12 in maintaining occult cancer in an equilibrium state. Cancer Res 2012; 72:3987-96; http://dx.doi.org/10.1158/0008-5472.CAN-12-1337
    • (2012) Cancer Res , vol.72 , pp. 3987-3996
    • Teng, M.W.1    Vesely, M.D.2    Duret, H.3    McLaughlin, N.4    Towne, J.E.5    Schreiber, R.D.6
  • 14
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004; 21:137-48; http:// dx.doi.org/10.1016/j.immuni.2004.07.017
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 15
    • 78649586268 scopus 로고    scopus 로고
    • The biology of myeloidderived suppressor cells: the blessing and the curse of morphological and functional heterogeneity
    • Youn JI, Gabrilovich DI. The biology of myeloidderived suppressor cells: the blessing and the curse of morphological and functional heterogeneity. Eur J Immunol 2010; 40:2969-75; http:// dx.doi.org/10.1002/eji.201040895
    • (2010) Eur J Immunol , vol.40 , pp. 2969-2975
    • Youn, J.I.1    Gabrilovich, D.I.2
  • 16
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan C. Nitric oxide and the immune response. Nat Immunol 2001; 2:907-16; http:// dx.doi.org/10.1038/ni1001-907
    • (2001) Nat Immunol , vol.2 , pp. 907-916
    • Bogdan, C.1
  • 17
    • 66949145484 scopus 로고    scopus 로고
    • Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells
    • Corzo CA, Cotter MJ, Cheng P, Cheng F, Kusmartsev S, Sotomayor E, et al. Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells. J Immunol 2009; 182:5693-701; http://dx.doi.org/10.4049/jimmunol. 0900092
    • (2009) J Immunol , vol.182 , pp. 5693-5701
    • Corzo, C.A.1    Cotter, M.J.2    Cheng, P.3    Cheng, F.4    Kusmartsev, S.5    Sotomayor, E.6
  • 18
    • 41149148269 scopus 로고    scopus 로고
    • Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives
    • Rodríguez PC, Ochoa AC. Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives. Immunol Rev 2008; 222:180-91; http://dx.doi.org/10.1111/j.1600-065X.2008.00608.x
    • (2008) Immunol Rev , vol.222 , pp. 180-191
    • Rodríguez, P.C.1    Ochoa, A.C.2
  • 20
    • 33846891555 scopus 로고    scopus 로고
    • Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma
    • Ochoa AC, Zea AH, Hernandez C, Rodriguez PC. Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma. Clin Cancer Res 2007; 13:721s-6s; http://dx.doi. org/10.1158/1078-0432.CCR-06-2197
    • (2007) Clin Cancer Res , vol.13
    • Ochoa, A.C.1    Zea, A.H.2    Hernandez, C.3    Rodriguez, P.C.4
  • 21
    • 60349113226 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: a novel therapeutic target
    • Ko JS, Bukowski RM, Fincke JH. Myeloid-derived suppressor cells: a novel therapeutic target. Curr Oncol Rep 2009; 11:87-93; http://dx.doi. org/10.1007/s11912-009-0014-6
    • (2009) Curr Oncol Rep , vol.11 , pp. 87-93
    • Ko, J.S.1    Bukowski, R.M.2    Fincke, J.H.3
  • 22
    • 41149119143 scopus 로고    scopus 로고
    • Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells
    • Marigo I, Dolcetti L, Serafini P, Zanovello P, Bronte V. Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells. Immunol Rev 2008; 222:162-79; http://dx.doi. org/10.1111/j.1600-065X.2008.00602.x
    • (2008) Immunol Rev , vol.222 , pp. 162-179
    • Marigo, I.1    Dolcetti, L.2    Serafini, P.3    Zanovello, P.4    Bronte, V.5
  • 23
    • 4143130091 scopus 로고    scopus 로고
    • Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigenspecific T-cell responses
    • Rodriguez PC, Quiceno DG, Zabaleta J, Ortiz B, Zea AH, Piazuelo MB, et al. Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigenspecific T-cell responses. Cancer Res 2004; 64:5839-49; http://dx.doi.org/10.1158/0008-5472.CAN-04-0465
    • (2004) Cancer Res , vol.64 , pp. 5839-5849
    • Rodriguez, P.C.1    Quiceno, D.G.2    Zabaleta, J.3    Ortiz, B.4    Zea, A.H.5    Piazuelo, M.B.6
  • 24
    • 0041845173 scopus 로고    scopus 로고
    • L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes
    • Rodriguez PC, Zea AH, DeSalvo J, Culotta KS, Zabaleta J, Quiceno DG, et al. L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes. J Immunol 2003; 171:1232-9.
    • (2003) J Immunol , vol.171 , pp. 1232-1239
    • Rodriguez, P.C.1    Zea, A.H.2    DeSalvo, J.3    Culotta, K.S.4    Zabaleta, J.5    Quiceno, D.G.6
  • 25
    • 33846933459 scopus 로고    scopus 로고
    • L-arginine availability regulates T-lymphocyte cell-cycle progression
    • Rodriguez PC, Quiceno DG, Ochoa AC. L-arginine availability regulates T-lymphocyte cell-cycle progression. Blood 2007; 109:1568-73; http://dx.doi.org/10.1182/blood-2006-06-031856
    • (2007) Blood , vol.109 , pp. 1568-1573
    • Rodriguez, P.C.1    Quiceno, D.G.2    Ochoa, A.C.3
  • 26
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9:162-74; http:// dx.doi.org/10.1038/nri2506
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 27
    • 0032526629 scopus 로고    scopus 로고
    • Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway
    • Bingisser RM, Tilbrook PA, Holt PG, Kees UR. Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway. J Immunol 1998; 160:5729-34.
    • (1998) J Immunol , vol.160 , pp. 5729-5734
    • Bingisser, R.M.1    Tilbrook, P.A.2    Holt, P.G.3    Kees, U.R.4
  • 28
    • 1642407149 scopus 로고    scopus 로고
    • Inhibition of MHC II gene transcription by nitric oxide and antioxidants
    • Harari O, Liao JK. Inhibition of MHC II gene transcription by nitric oxide and antioxidants. Curr Pharm Des 2004; 10:893-8; http://dx.doi. org/10.2174/1381612043452893
    • (2004) Curr Pharm Des , vol.10 , pp. 893-898
    • Harari, O.1    Liao, J.K.2
  • 29
    • 18744371278 scopus 로고    scopus 로고
    • Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction
    • Rivoltini L, Carrabba M, Huber V, Castelli C, Novellino L, Dalerba P, et al. Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction. Immunol Rev 2002; 188:97-113; http://dx.doi.org/10.1034/j.1600-065X.2002.18809.x
    • (2002) Immunol Rev , vol.188 , pp. 97-113
    • Rivoltini, L.1    Carrabba, M.2    Huber, V.3    Castelli, C.4    Novellino, L.5    Dalerba, P.6
  • 30
    • 34848887822 scopus 로고    scopus 로고
    • Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy
    • Talmadge JE. Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy. Clin Cancer Res 2007; 13:5243-8; http://dx.doi.org/10.1158/1078-0432.CCR-07-0182
    • (2007) Clin Cancer Res , vol.13 , pp. 5243-5248
    • Talmadge, J.E.1
  • 31
    • 34447118098 scopus 로고    scopus 로고
    • Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer
    • Nagaraj S, Gupta K, Pisarev V, Kinarsky L, Sherman S, Kang L, et al. Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer. Nat Med 2007; 13:828-35; http:// dx.doi.org/10.1038/nm1609
    • (2007) Nat Med , vol.13 , pp. 828-835
    • Nagaraj, S.1    Gupta, K.2    Pisarev, V.3    Kinarsky, L.4    Sherman, S.5    Kang, L.6
  • 32
    • 25444456369 scopus 로고    scopus 로고
    • Tumorassociated CD8+ T cell tolerance induced by bone marrow-derived immature myeloid cells
    • Kusmartsev S, Nagaraj S, Gabrilovich DI. Tumorassociated CD8+ T cell tolerance induced by bone marrow-derived immature myeloid cells. J Immunol 2005; 175:4583-92.
    • (2005) J Immunol , vol.175 , pp. 4583-4592
    • Kusmartsev, S.1    Nagaraj, S.2    Gabrilovich, D.I.3
  • 33
    • 36348989162 scopus 로고    scopus 로고
    • Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells
    • Nefedova Y, Fishman M, Sherman S, Wang X, Beg AA, Gabrilovich DI. Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells. Cancer Res 2007; 67:11021-8; http://dx.doi.org/10.1158/0008-5472.CAN-07-2593
    • (2007) Cancer Res , vol.67 , pp. 11021-11028
    • Nefedova, Y.1    Fishman, M.2    Sherman, S.3    Wang, X.4    Beg, A.A.5    Gabrilovich, D.I.6
  • 34
    • 2942618999 scopus 로고    scopus 로고
    • Reactive oxygen species production by blood neutrophils of patients with laryngeal carcinoma and antioxidative enzyme activity in their blood
    • Szuster-Ciesielska A, Hryciuk-Umer E, Stepulak A, Kupisz K, Kandefer-Szersze M. Reactive oxygen species production by blood neutrophils of patients with laryngeal carcinoma and antioxidative enzyme activity in their blood. Acta Oncol 2004; 43:252-8; http://dx.doi.org/10.1080/02841860410029708
    • (2004) Acta Oncol , vol.43 , pp. 252-258
    • Szuster-Ciesielska, A.1    Hryciuk-Umer, E.2    Stepulak, A.3    Kupisz, K.4    Kandefer-Szersze, M.5
  • 35
    • 0035874990 scopus 로고    scopus 로고
    • Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients
    • Schmielau J, Finn OJ. Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients. Cancer Res 2001; 61:4756-60.
    • (2001) Cancer Res , vol.61 , pp. 4756-4760
    • Schmielau, J.1    Finn, O.J.2
  • 36
    • 1642536454 scopus 로고    scopus 로고
    • Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species
    • Kusmartsev S, Nefedova Y, Yoder D, Gabrilovich DI. Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species. J Immunol 2004; 172:989-99.
    • (2004) J Immunol , vol.172 , pp. 989-999
    • Kusmartsev, S.1    Nefedova, Y.2    Yoder, D.3    Gabrilovich, D.I.4
  • 38
    • 44849109660 scopus 로고    scopus 로고
    • Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor-alpha 2
    • Fichtner-Feigl S, Terabe M, Kitani A, Young CA, Fuss I, Geissler EK, et al. Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor-alpha 2. Cancer Res 2008; 68:3467-75; http://dx.doi.org/10.1158/0008-5472.CAN-07-5301
    • (2008) Cancer Res , vol.68 , pp. 3467-3475
    • Fichtner-Feigl, S.1    Terabe, M.2    Kitani, A.3    Young, C.A.4    Fuss, I.5    Geissler, E.K.6
  • 39
    • 10744220561 scopus 로고    scopus 로고
    • Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence
    • Terabe M, Matsui S, Park JM, Mamura M, Noben-Trauth N, Donaldson DD, et al. Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence. J Exp Med 2003; 198:1741-52; http://dx.doi.org/10.1084/jem.20022227
    • (2003) J Exp Med , vol.198 , pp. 1741-1752
    • Terabe, M.1    Matsui, S.2    Park, J.M.3    Mamura, M.4    Noben-Trauth, N.5    Donaldson, D.D.6
  • 40
    • 37349100945 scopus 로고    scopus 로고
    • Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis
    • Yang L, Huang J, Ren X, Gorska AE, Chytil A, Aakre M, et al. Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell 2008; 13:23-35; http://dx.doi.org/10.1016/j. ccr.2007.12.004
    • (2008) Cancer Cell , vol.13 , pp. 23-35
    • Yang, L.1    Huang, J.2    Ren, X.3    Gorska, A.E.4    Chytil, A.5    Aakre, M.6
  • 41
    • 75149123468 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine
    • Srivastava MK, Sinha P, Clements VK, Rodriguez P, Ostrand-Rosenberg S. Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer Res 2010; 70:68-77; http://dx.doi.org/10.1158/0008-5472.CAN-09-2587
    • (2010) Cancer Res , vol.70 , pp. 68-77
    • Srivastava, M.K.1    Sinha, P.2    Clements, V.K.3    Rodriguez, P.4    Ostrand-Rosenberg, S.5
  • 42
    • 70249140303 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells
    • Hanson EM, Clements VK, Sinha P, Ilkovitch D, Ostrand-Rosenberg S. Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells. J Immunol 2009; 183:937-44; http://dx.doi.org/10.4049/jimmunol. 0804253
    • (2009) J Immunol , vol.183 , pp. 937-944
    • Hanson, E.M.1    Clements, V.K.2    Sinha, P.3    Ilkovitch, D.4    Ostrand-Rosenberg, S.5
  • 43
    • 34548805636 scopus 로고    scopus 로고
    • Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
    • Sinha P, Clements VK, Bunt SK, Albelda SM, Ostrand-Rosenberg S. Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J Immunol 2007; 179:977-83.
    • (2007) J Immunol , vol.179 , pp. 977-983
    • Sinha, P.1    Clements, V.K.2    Bunt, S.K.3    Albelda, S.M.4    Ostrand-Rosenberg, S.5
  • 44
    • 33746115391 scopus 로고    scopus 로고
    • CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cells
    • Yang R, Cai Z, Zhang Y, Yutzy WH 4th, Roby KF, Roden RB. CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cells. Cancer Res 2006; 66:6807-15; http://dx.doi.org/10.1158/0008-5472.CAN-05-3755
    • (2006) Cancer Res , vol.66 , pp. 6807-6815
    • Yang, R.1    Cai, Z.2    Zhang, Y.3    Yutzy IV, W.H.4    Roby, K.F.5    Roden, R.B.6
  • 45
    • 48549085973 scopus 로고    scopus 로고
    • Myeloidderived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
    • Serafini P, Mgebroff S, Noonan K, Borrello I. Myeloidderived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res 2008; 68:5439-49; http://dx.doi.org/10.1158/0008-5472.CAN-07-6621
    • (2008) Cancer Res , vol.68 , pp. 5439-5449
    • Serafini, P.1    Mgebroff, S.2    Noonan, K.3    Borrello, I.4
  • 46
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • Huang B, Pan PY, Li Q, Sato AI, Levy DE, Bromberg J, et al. Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 2006; 66:1123-31; http://dx.doi.org/10.1158/0008-5472.CAN-05-1299
    • (2006) Cancer Res , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6
  • 47
    • 59849126377 scopus 로고    scopus 로고
    • Cancerexpanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1
    • Li H, Han Y, Guo Q, Zhang M, Cao X. Cancerexpanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J Immunol 2009; 182:240-9.
    • (2009) J Immunol , vol.182 , pp. 240-249
    • Li, H.1    Han, Y.2    Guo, Q.3    Zhang, M.4    Cao, X.5
  • 48
    • 34248342290 scopus 로고    scopus 로고
    • Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host
    • Liu C, Yu S, Kappes J, Wang J, Grizzle WE, Zinn KR, et al. Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host. Blood 2007; 109:4336-42; http:// dx.doi.org/10.1182/blood-2006-09-046201
    • (2007) Blood , vol.109 , pp. 4336-4342
    • Liu, C.1    Yu, S.2    Kappes, J.3    Wang, J.4    Grizzle, W.E.5    Zinn, K.R.6
  • 49
    • 78649610261 scopus 로고    scopus 로고
    • IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function
    • Elkabets M, Ribeiro VS, Dinarello CA, Ostrand-Rosenberg S, Di Santo JP, Apte RN, et al. IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. Eur J Immunol 2010; 40:3347-57; http:// dx.doi.org/10.1002/eji.201041037
    • (2010) Eur J Immunol , vol.40 , pp. 3347-3357
    • Elkabets, M.1    Ribeiro, V.S.2    Dinarello, C.A.3    Ostrand-Rosenberg, S.4    Di Santo, J.P.5    Apte, R.N.6
  • 50
    • 29144484782 scopus 로고    scopus 로고
    • A nonclassical non-Valpha14Jalpha18 CD1d-restricted (Type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance
    • Terabe M, Swann J, Ambrosino E, Sinha P, Takaku S, Hayakawa Y, et al. A nonclassical non-Valpha14Jalpha18 CD1d-restricted (Type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance. J Exp Med 2005; 202:1627-33; http://dx.doi.org/10.1084/jem.20051381
    • (2005) J Exp Med , vol.202 , pp. 1627-1633
    • Terabe, M.1    Swann, J.2    Ambrosino, E.3    Sinha, P.4    Takaku, S.5    Hayakawa, Y.6
  • 51
    • 0038746593 scopus 로고    scopus 로고
    • Inhibition of early tumor growth requires J alpha 18-positive (natural killer T) cells
    • Stewart TJ, Smyth MJ, Fernando GJ, Frazer IH, Leggatt GR. Inhibition of early tumor growth requires J alpha 18-positive (natural killer T) cells. Cancer Res 2003; 63:3058-60.
    • (2003) Cancer Res , vol.63 , pp. 3058-3060
    • Stewart, T.J.1    Smyth, M.J.2    Fernando, G.J.3    Frazer, I.H.4    Leggatt, G.R.5
  • 52
    • 1642300508 scopus 로고    scopus 로고
    • Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment
    • Chantrain CF, Shimada H, Jodele S, Groshen S, Ye W, Shalinsky DR, et al. Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment. Cancer Res 2004; 64:1675-86; http://dx.doi. org/10.1158/0008-5472.CAN-03-0160
    • (2004) Cancer Res , vol.64 , pp. 1675-1686
    • Chantrain, C.F.1    Shimada, H.2    Jodele, S.3    Groshen, S.4    Ye, W.5    Shalinsky, D.R.6
  • 53
    • 34547820876 scopus 로고    scopus 로고
    • Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells
    • Shojaei F, Wu X, Malik AK, Zhong C, Baldwin ME, Schanz S, et al. Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells. Nat Biotechnol 2007; 25:911-20; http://dx.doi.org/10.1038/nbt1323
    • (2007) Nat Biotechnol , vol.25 , pp. 911-920
    • Shojaei, F.1    Wu, X.2    Malik, A.K.3    Zhong, C.4    Baldwin, M.E.5    Schanz, S.6
  • 54
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat Med 2004; 10:909-15; http://dx.doi. org/10.1038/nm1100
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 55
    • 33749461167 scopus 로고    scopus 로고
    • All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients
    • Mirza N, Fishman M, Fricke I, Dunn M, Neuger AM, Frost TJ, et al. All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients. Cancer Res 2006; 66:9299-307; http://dx.doi.org/10.1158/0008-5472.CAN-06-1690
    • (2006) Cancer Res , vol.66 , pp. 9299-9307
    • Mirza, N.1    Fishman, M.2    Fricke, I.3    Dunn, M.4    Neuger, A.M.5    Frost, T.J.6
  • 56
    • 0042591427 scopus 로고    scopus 로고
    • All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination
    • Kusmartsev S, Cheng F, Yu B, Nefedova Y, Sotomayor E, Lush R, et al. All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination. Cancer Res 2003; 63:4441-9.
    • (2003) Cancer Res , vol.63 , pp. 4441-4449
    • Kusmartsev, S.1    Cheng, F.2    Yu, B.3    Nefedova, Y.4    Sotomayor, E.5    Lush, R.6
  • 57
    • 79958061935 scopus 로고    scopus 로고
    • Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions
    • Zhou J, Wu J, Chen X, Fortenbery N, Eksioglu E, Kodumudi KN, et al. Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions. Int Immunopharmacol 2011; 11:890-8; http://dx.doi.org/10.1016/j. intimp.2011.01.007
    • (2011) Int Immunopharmacol , vol.11 , pp. 890-898
    • Zhou, J.1    Wu, J.2    Chen, X.3    Fortenbery, N.4    Eksioglu, E.5    Kodumudi, K.N.6
  • 58
    • 61449220940 scopus 로고    scopus 로고
    • Immunosuppressive myeloid-derived suppressor cells can be converted into immunogenic APCs with the help of activated NKT cells: an alternative cell-based antitumor vaccine
    • Ko HJ, Lee JM, Kim YJ, Kim YS, Lee KA, Kang CY. Immunosuppressive myeloid-derived suppressor cells can be converted into immunogenic APCs with the help of activated NKT cells: an alternative cell-based antitumor vaccine. J Immunol 2009; 182:1818-28; http://dx.doi.org/10.4049/jimmunol. 0802430
    • (2009) J Immunol , vol.182 , pp. 1818-1828
    • Ko, H.J.1    Lee, J.M.2    Kim, Y.J.3    Kim, Y.S.4    Lee, K.A.5    Kang, C.Y.6
  • 59
    • 20844451391 scopus 로고    scopus 로고
    • Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients
    • Chang DH, Osman K, Connolly J, Kukreja A, Krasovsky J, Pack M, et al. Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients. J Exp Med 2005; 201:1503-17; http://dx.doi.org/10.1084/ jem.20042592
    • (2005) J Exp Med , vol.201 , pp. 1503-1517
    • Chang, D.H.1    Osman, K.2    Connolly, J.3    Kukreja, A.4    Krasovsky, J.5    Pack, M.6
  • 60
    • 84871341847 scopus 로고    scopus 로고
    • Polysaccharide from Lentinus edodes inhibits the immunosuppressive function of myeloidderived suppressor cells
    • Wu H, Tao N, Liu X, Li X, Tang J, Ma C, et al. Polysaccharide from Lentinus edodes inhibits the immunosuppressive function of myeloidderived suppressor cells. PLoS One 2012; 7:e51751; http://dx.doi.org/10.1371/journal. pone.0051751
    • (2012) PLoS One , vol.7
    • Wu, H.1    Tao, N.2    Liu, X.3    Li, X.4    Tang, J.5    Ma, C.6
  • 61
    • 34547578958 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (cox-2) and the inflammogenesis of cancer
    • Harris RE. Cyclooxygenase-2 (cox-2) and the inflammogenesis of cancer. Subcell Biochem 2007; 42:93-126; http://dx.doi.org/10.1007/1-4020-5688-5_4
    • (2007) Subcell Biochem , vol.42 , pp. 93-126
    • Harris, R.E.1
  • 62
    • 34249300128 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
    • Sinha P, Clements VK, Fulton AM, Ostrand-Rosenberg S. Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res 2007; 67:4507-13; http://dx.doi. org/10.1158/0008-5472.CAN-06-4174
    • (2007) Cancer Res , vol.67 , pp. 4507-4513
    • Sinha, P.1    Clements, V.K.2    Fulton, A.M.3    Ostrand-Rosenberg, S.4
  • 63
    • 33845997430 scopus 로고    scopus 로고
    • Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion
    • Talmadge JE, Hood KC, Zobel LC, Shafer LR, Coles M, Toth B. Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion. Int Immunopharmacol 2007; 7:140-51; http://dx.doi.org/10.1016/j. intimp.2006.09.021
    • (2007) Int Immunopharmacol , vol.7 , pp. 140-151
    • Talmadge, J.E.1    Hood, K.C.2    Zobel, L.C.3    Shafer, L.R.4    Coles, M.5    Toth, B.6
  • 65
    • 33751531874 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function
    • Serafini P, Meckel K, Kelso M, Noonan K, Califano J, Koch W, et al. Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function. J Exp Med 2006; 203:2691-702; http://dx.doi. org/10.1084/jem.20061104
    • (2006) J Exp Med , vol.203 , pp. 2691-2702
    • Serafini, P.1    Meckel, K.2    Kelso, M.3    Noonan, K.4    Califano, J.5    Koch, W.6
  • 66
    • 20144375187 scopus 로고    scopus 로고
    • Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination.
    • De Santo C, Serafini P, Marigo I, Dolcetti L, Bolla M, Del Soldato P, et al. Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination. Proc Natl Acad Sci U S A 2005; 102:4185-90; http:// dx.doi.org/10.1073/pnas.0409783102
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 4185-4190
    • De Santo, C.1    Serafini, P.2    Marigo, I.3    Dolcetti, L.4    Bolla, M.5    Del Soldato, P.6
  • 67
    • 34548257176 scopus 로고    scopus 로고
    • HIF-dependent antitumorigenic effect of antioxidants in vivo
    • Gao P, Zhang H, Dinavahi R, Li F, Xiang Y, Raman V, et al. HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell 2007; 12:230-8; http://dx.doi.org/10.1016/j. ccr.2007.08.004
    • (2007) Cancer Cell , vol.12 , pp. 230-238
    • Gao, P.1    Zhang, H.2    Dinavahi, R.3    Li, F.4    Xiang, Y.5    Raman, V.6
  • 68
    • 0036785631 scopus 로고    scopus 로고
    • Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model
    • Heckelsmiller K, Rall K, Beck S, Schlamp A, Seiderer J, Jahrsdörfer B, et al. Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model. J Immunol 2002; 169:3892-9.
    • (2002) J Immunol , vol.169 , pp. 3892-3899
    • Heckelsmiller, K.1    Rall, K.2    Beck, S.3    Schlamp, A.4    Seiderer, J.5    Jahrsdörfer, B.6
  • 69
    • 0035500280 scopus 로고    scopus 로고
    • NK- and CD8(+) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides
    • Kawarada Y, Ganss R, Garbi N, Sacher T, Arnold B, Hämmerling GJ. NK- and CD8(+) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides. J Immunol 2001; 167:5247-53.
    • (2001) J Immunol , vol.167 , pp. 5247-5253
    • Kawarada, Y.1    Ganss, R.2    Garbi, N.3    Sacher, T.4    Arnold, B.5    Hämmerling, G.J.6
  • 70
    • 84856824651 scopus 로고    scopus 로고
    • Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells
    • Shirota Y, Shirota H, Klinman DM. Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells. J Immunol 2012; 188:1592-9; http://dx.doi. org/10.4049/jimmunol.1101304
    • (2012) J Immunol , vol.188 , pp. 1592-1599
    • Shirota, Y.1    Shirota, H.2    Klinman, D.M.3
  • 72
    • 34548125294 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses
    • Fricke I, Mirza N, Dupont J, Lockhart C, Jackson A, Lee JH, et al. Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses. Clin Cancer Res 2007; 13:4840-8; http://dx.doi.org/10.1158/1078-0432.CCR-07-0409
    • (2007) Clin Cancer Res , vol.13 , pp. 4840-4848
    • Fricke, I.1    Mirza, N.2    Dupont, J.3    Lockhart, C.4    Jackson, A.5    Lee, J.H.6
  • 73
    • 37049006066 scopus 로고    scopus 로고
    • Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma
    • Melani C, Sangaletti S, Barazzetta FM, Werb Z, Colombo MP. Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma. Cancer Res 2007; 67:11438-46; http://dx.doi.org/10.1158/0008-5472.CAN-07-1882
    • (2007) Cancer Res , vol.67 , pp. 11438-11446
    • Melani, C.1    Sangaletti, S.2    Barazzetta, F.M.3    Werb, Z.4    Colombo, M.P.5
  • 74
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to antiangiogenic therapy
    • Bergers G, Hanahan D. Modes of resistance to antiangiogenic therapy. Nat Rev Cancer 2008; 8:592-603; http://dx.doi.org/10.1038/nrc2442
    • (2008) Nat Rev Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 76
    • 0034485823 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival
    • Ekmekcioglu S, Ellerhorst J, Smid CM, Prieto VG, Munsell M, Buzaid AC, et al. Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival. Clin Cancer Res 2000; 6:4768-75.
    • (2000) Clin Cancer Res , vol.6 , pp. 4768-4775
    • Ekmekcioglu, S.1    Ellerhorst, J.2    Smid, C.M.3    Prieto, V.G.4    Munsell, M.5    Buzaid, A.C.6
  • 77
    • 78049426509 scopus 로고    scopus 로고
    • Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients
    • Glynn SA, Boersma BJ, Dorsey TH, Yi M, Yfantis HG, Ridnour LA, et al. Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients. J Clin Invest 2010; 120:3843-54; http://dx.doi.org/10.1172/ JCI42059
    • (2010) J Clin Invest , vol.120 , pp. 3843-3854
    • Glynn, S.A.1    Boersma, B.J.2    Dorsey, T.H.3    Yi, M.4    Yfantis, H.G.5    Ridnour, L.A.6
  • 78
    • 84862533368 scopus 로고    scopus 로고
    • The role of melanoma tumor-derived nitric oxide in the tumor inflammatory microenvironment: its impact on the chemokine expression profile, including suppression of CXCL10
    • Tanese K, Grimm EA, Ekmekcioglu S. The role of melanoma tumor-derived nitric oxide in the tumor inflammatory microenvironment: its impact on the chemokine expression profile, including suppression of CXCL10. Int J Cancer 2012; 131:891-901; http://dx.doi.org/10.1002/ ijc.26451
    • (2012) Int J Cancer , vol.131 , pp. 891-901
    • Tanese, K.1    Grimm, E.A.2    Ekmekcioglu, S.3
  • 79
    • 84862076074 scopus 로고    scopus 로고
    • Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release
    • Jayaraman P, Parikh F, Lopez-Rivera E, Hailemichael Y, Clark A, Ma G, et al. Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release. J Immunol 2012; 188:5365-76; http://dx.doi.org/10.4049/jimmunol.1103553
    • (2012) J Immunol , vol.188 , pp. 5365-5376
    • Jayaraman, P.1    Parikh, F.2    Lopez-Rivera, E.3    Hailemichael, Y.4    Clark, A.5    Ma, G.6
  • 80
    • 84858202940 scopus 로고    scopus 로고
    • Aptamer-mediated blockade of IL4Rα triggers apoptosis of MDSCs and limits tumor progression
    • Roth F, De La Fuente AC, Vella JL, Zoso A, Inverardi L, Serafini P. Aptamer-mediated blockade of IL4Rα triggers apoptosis of MDSCs and limits tumor progression. Cancer Res 2012; 72:1373-83; http://dx.doi.org/10.1158/0008-5472.CAN-11-2772
    • (2012) Cancer Res , vol.72 , pp. 1373-1383
    • Roth, F.1    De La Fuente, A.C.2    Vella, J.L.3    Zoso, A.4    Inverardi, L.5    Serafini, P.6
  • 81
    • 33749425534 scopus 로고    scopus 로고
    • Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells
    • Gallina G, Dolcetti L, Serafini P, De Santo C, Marigo I, Colombo MP, et al. Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest 2006; 116:2777-90; http://dx.doi.org/10.1172/JCI28828
    • (2006) J Clin Invest , vol.116 , pp. 2777-2790
    • Gallina, G.1    Dolcetti, L.2    Serafini, P.3    De Santo, C.4    Marigo, I.5    Colombo, M.P.6
  • 83
    • 84863248624 scopus 로고    scopus 로고
    • Curcumin induces the differentiation of myeloidderived suppressor cells and inhibits their interaction with cancer cells and related tumor growth.
    • Tu SP, Jin H, Shi JD, Zhu LM, Suo Y, Lu G, et al. Curcumin induces the differentiation of myeloidderived suppressor cells and inhibits their interaction with cancer cells and related tumor growth. Cancer Prev Res (Phila) 2012; 5:205-15; http://dx.doi.org/10.1158/1940-6207.CAPR-11-0247
    • (2012) Cancer Prev Res (Phila) , vol.5 , pp. 205-215
    • Tu, S.P.1    Jin, H.2    Shi, J.D.3    Zhu, L.M.4    Suo, Y.5    Lu, G.6
  • 84
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/ CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • Suzuki E, Kapoor V, Jassar AS, Kaiser LR, Albelda SM. Gemcitabine selectively eliminates splenic Gr-1+/ CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res 2005; 11:6713-21; http://dx.doi.org/10.1158/1078-0432.CCR-05-0883
    • (2005) Clin Cancer Res , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 85
    • 77951086882 scopus 로고    scopus 로고
    • 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity
    • Vincent J, Mignot G, Chalmin F, Ladoire S, Bruchard M, Chevriaux A, et al. 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity. Cancer Res 2010; 70:3052-61; http://dx.doi.org/10.1158/0008-5472.CAN-09-3690
    • (2010) Cancer Res , vol.70 , pp. 3052-3061
    • Vincent, J.1    Mignot, G.2    Chalmin, F.3    Ladoire, S.4    Bruchard, M.5    Chevriaux, A.6
  • 86
    • 84872086179 scopus 로고    scopus 로고
    • Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
    • Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, et al. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med 2013; 19:57-64; http://dx.doi.org/10.1038/nm.2999
    • (2013) Nat Med , vol.19 , pp. 57-64
    • Bruchard, M.1    Mignot, G.2    Derangère, V.3    Chalmin, F.4    Chevriaux, A.5    Végran, F.6
  • 87
    • 84874116665 scopus 로고    scopus 로고
    • Metronomic chemotherapy with low-dose cyclophosphamide plus gemcitabine can induce anti-tumor T cell immunity in vivo
    • Tongu M, Harashima N, Monma H, Inao T, Yamada T, Kawauchi H, et al. Metronomic chemotherapy with low-dose cyclophosphamide plus gemcitabine can induce anti-tumor T cell immunity in vivo. Cancer Immunol Immunother 2013; 62:383-91; http://dx.doi. org/10.1007/s00262-012-1343-0.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 383-391
    • Tongu, M.1    Harashima, N.2    Monma, H.3    Inao, T.4    Yamada, T.5    Kawauchi, H.6
  • 88
    • 77956680680 scopus 로고    scopus 로고
    • A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers
    • Kodumudi KN, Woan K, Gilvary DL, Sahakian E, Wei S, Djeu JY. A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers. Clin Cancer Res 2010; 16:4583-94; http://dx.doi. org/10.1158/1078-0432.CCR-10-0733
    • (2010) Clin Cancer Res , vol.16 , pp. 4583-4594
    • Kodumudi, K.N.1    Woan, K.2    Gilvary, D.L.3    Sahakian, E.4    Wei, S.5    Djeu, J.Y.6
  • 89
    • 84869791457 scopus 로고    scopus 로고
    • Blockade of myeloid-derived suppressor cells after induction of lymphopenia improves adoptive T cell therapy in a murine model of melanoma
    • Kodumudi KN, Weber A, Sarnaik AA, Pilon-Thomas S. Blockade of myeloid-derived suppressor cells after induction of lymphopenia improves adoptive T cell therapy in a murine model of melanoma. J Immunol 2012; 189:5147-54; http://dx.doi. org/10.4049/jimmunol.1200274
    • (2012) J Immunol , vol.189 , pp. 5147-5154
    • Kodumudi, K.N.1    Weber, A.2    Sarnaik, A.A.3    Pilon-Thomas, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.