Prostaglandin E2 deficiency causes a phenotype of aspirin sensitivity that depends on platelets and cysteinyl leukotrienes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 42, 2013, Pages 16987-16992

  Liu, Tao ^a,b   Laidlaw, Tanya M ^a,b   Katz, Howard R ^a,b   Boyce, Joshua A ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ARACHIDONATE 5 LIPOXYGENASE; CYCLOOXYGENASE 2 INHIBITOR; LYSINE ACETYLSALICYLATE; PEPTIDOLEUKOTRIENE; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 3; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; PROSTANOID RECEPTOR; T PROSTANOID RECEPTOR; UNCLASSIFIED DRUG; ANTITHROMBOCYTIC AGENT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ISOMERASE; LEUKOTRIENE D4 RECEPTOR; LEUKOTRIENE RECEPTOR; MEMBRANE PROTEIN; PROSTAGLANDIN E SYNTHASE; PTGS1 PROTEIN, MOUSE; PTGS2 PROTEIN, MOUSE;

AIRWAY RESISTANCE; ARTICLE; ASPIRIN EXACERBATED RESPIRATORY DISEASE; BRONCHOSPASM; DRUG SENSITIVITY; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE; ANIMAL; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; ASTHMA, ASPIRIN-INDUCED;

AIRWAY RESISTANCE; ANIMALS; ASTHMA, ASPIRIN-INDUCED; BLOOD PLATELETS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DINOPROSTONE; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MAST CELLS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PLATELET AGGREGATION INHIBITORS; RECEPTORS, LEUKOTRIENE;

EID: 84885693969     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313185110     Document Type: Article

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