Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma

Journal of Clinical Investigation

Volumn 101, Issue 4, 1998, Pages 834-846

  Cowburn, Andrew S ^a   Sladek, Krzysztof ^b   Soja, Jerzy ^b   Adamek, Lukasz ^b   Nizankowska, Ewa ^b   Szczeklik, Andrzej ^b   Lam, Bing K ^c   Penrose, John F ^c   Austen, K Frank ^c   Holgate, Stephen T ^a   Sampson, Anthony P ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

5 lipoxygenase; Aspirin; Asthma; Cyclooxygenase; Leukotriene C4 synthase

Indexed keywords

ACETYLSALICYLIC ACID; ARACHIDONATE 5 LIPOXYGENASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; IMMUNOGLOBULIN E; LEUKOTRIENE; LEUKOTRIENE A4 HYDROLASE; LEUKOTRIENE C4; LEUKOTRIENE D4; LEUKOTRIENE E4; PEPTIDOLEUKOTRIENE; PREDNISOLONE; PROSTAGLANDIN E2; PROSTANOID; PROTEIN; STEROID; SYNTHETASE; CYTOKINE; GLUTATHIONE TRANSFERASE; LEUKOTRIENE C4 SYNTHASE; LEUKOTRIENE-C4 SYNTHASE; PLACEBO;

ADULT; AGED; ARTICLE; ASTHMA; BRONCHOSCOPY; BRONCHOSPASM; BRONCHUS; BRONCHUS BIOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME IMMUNOASSAY; EOSINOPHIL; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INHALATIONAL DRUG ADMINISTRATION; LUNG LAVAGE; MACROPHAGE; MALE; MAST CELL; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPIROMETRY; BIOPSY; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; CYTOLOGY; ENZYMOLOGY; IMMUNOLOGY; LEUKOCYTE COUNT; PATHOLOGY; T LYMPHOCYTE;

ASPIRIN; ASTHMA; BIOPSY; BRONCHI; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; EOSINOPHILS; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; LEUKOCYTE COUNT; LEUKOTRIENES; MALE; PLACEBOS; T-LYMPHOCYTES;

EID: 0032519008     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI620     Document Type: Article

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