Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2in house dust mite-induced allergic pulmonary inflammation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 31, 2012, Pages 12692-12697

  Liu, Tao ^a   Laidlaw, Tanya M ^a,b   Feng, Chunli ^a   Xing, Wei ^a   Shen, Shiliang ^a   Milne, Ginger L ^c   Boyce, Joshua A ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

Cyclooxygenase; EP receptors

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; INTERCELLULAR ADHESION MOLECULE 1; PROSTAGLANDIN E2; PROTEIN KINASE C; THROMBOXANE A2; ALLERGEN; HOUSE DUST ALLERGEN; ICAM1 PROTEIN, MOUSE; ISOMERASE; PROSTAGLANDIN E RECEPTOR 1; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E SYNTHASE; PTGER1 PROTEIN, MOUSE; THROMBOXANE RECEPTOR;

ALLERGIC PNEUMONITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CYTOKINE PRODUCTION; DERMATOPHAGOIDES; EX VIVO STUDY; FEMALE; HEMATOPOIETIC CELL; LOEFFLER PNEUMONIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ASTHMA; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENETICS; IMMUNOLOGY; MOUSE MUTANT; PNEUMONIA;

MUS; PYROGLYPHIDAE;

ALLERGENS; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; ASTHMA; DINOPROSTONE; INTERCELLULAR ADHESION MOLECULE-1; INTRAMOLECULAR OXIDOREDUCTASES; MALE; MICE; MICE, KNOCKOUT; PNEUMONIA; PULMONARY EOSINOPHILIA; RECEPTORS, PROSTAGLANDIN E, EP1 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; RECEPTORS, THROMBOXANE; SIGNAL TRANSDUCTION; THROMBOXANE A2; UP-REGULATION;

EID: 84864524232     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1207816109     Document Type: Article

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