Platelet depletion by anti-CD41 (αIIb) mAb injection early but not late in the course of disease protects against Plasmodium berghei pathogenesis by altering the levels of pathogenic cytokines

Blood

Volumn 105, Issue 5, 2005, Pages 1956-1963

  Van Der Heyde, Henri C ^a   Gramaglia, Irene ^b   Sun, Guang ^b   Woods, Catherine ^b  

^a LA JOLLA BIOENGINEERING INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD61 ANTIGEN; CYTOKINE; FIBRINOGEN RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; BETA3 INTEGRIN; GLYCOPROTEIN IIB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIUM; ERYTHROCYTE; FEMALE; MALARIA; MOUSE; NONHUMAN; PATHOGENESIS; PLASMODIUM BERGHEI; PRIORITY JOURNAL; THROMBOCYTE ADHESION; THROMBOCYTE FUNCTION; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CELL ADHESION; DISEASE MODEL; DRUG EFFECT; IMMUNOLOGY; PARTICLE SIZE; PHYSIOLOGY; THROMBOCYTE; THROMBOCYTE ADHESIVENESS; THROMBOCYTE COUNT; TIME;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD PLATELETS; CELL ADHESION; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; INTEGRIN BETA3; MALARIA; MICE; MICE, INBRED C57BL; PARTICLE SIZE; PLASMODIUM BERGHEI; PLATELET ADHESIVENESS; PLATELET COUNT; PLATELET MEMBRANE GLYCOPROTEIN IIB; TIME;

EID: 14944355918     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-06-2206     Document Type: Article

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