Prostaglandin E2 exerts homeostatic regulation of pulmonary vascular remodeling in allergic airway inflammation

Journal of Immunology

Volumn 184, Issue 1, 2010, Pages 433-441

  Lundequist, Anders ^a,b   Nallamshetty, Samridhi N ^a,b   Xing, Wei ^a,b   Feng, Chunli ^b   Laidlaw, Tanya M ^a,b   Uematsu, Satoshi ^c   Akira, Shizuo ^c   Boyce, Joshua A ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; PROSTAGLANDIN E2; PROSTANOID RECEPTOR; HOUSE DUST ALLERGEN; ISOMERASE; PROSTAGLANDIN E SYNTHASE;

ALLERGIC PNEUMONITIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CELL STIMULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATOPHAGOIDES FARINAE; EFFECTOR CELL; HISTOPATHOLOGY; HOMEOSTASIS AND REGULATION; HOUSE DUST; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; LUNG ALVEOLUS CELL; LUNG BLOOD VESSEL; LUNG LAVAGE; MASS FRAGMENTOGRAPHY; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SENSITIZATION; SPLEEN CELL; TH1 CELL; TH17 CELL; TH2 CELL; VASCULAR SMOOTH MUSCLE; ANIMAL; BRONCHUS HYPERREACTIVITY; GENETICS; HOMEOSTASIS; IMMUNOLOGY; LUNG; MICROBIOLOGY; MOUSE MUTANT; PATHOLOGY; VASCULARIZATION;

ANIMALS; ANTIGENS, DERMATOPHAGOIDES; BRONCHIAL HYPERREACTIVITY; DINOPROSTONE; HOMEOSTASIS; INTRAMOLECULAR OXIDOREDUCTASES; LUNG; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; PNEUMONIA;

EID: 73949137381     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902835     Document Type: Article

References (48)

1. Fortier, M. A., K. Krishnaswamy, G. Danyod, S. Boucher-Kovalik, and P. Chapdalaine. 2008. A postgenomic integrated view of prostaglandins in reproduction: implications for other body systems. J. Physiol. Pharmacol. 59 (Suppl 1): 65-89.
2. Uematsu, S., M. Matsumoto, K. Takeda, and S. Akira. 2002. Lipopolysaccharide-dependent prostaglandin E(2) production is regulated by the glutathionedependent prostaglandin E(2) synthase gene induced by the Toll-like receptor 4/MyD88/NF-IL6 pathway. J. Immunol. 168: 5811-5816.
3. 2 production by dendritic cells from subjects with asthma compared with normal subjects. Am. J. Respir. Crit. Care Med. 170: 485-491.
4. 2-related pathways by the Th2 cytokine IL-13. J. Allergy Clin. Immunol. 117: 1446-1454.
5. 2) on interleukin-1 β-induced cyclooxygenase-2 expression in human airway smooth-muscle cells. Am. J. Respir. Crit. Care Med. 162: 2272-2277.
6. 2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. J. Allergy Clin. Immunol. 111: 1041-1048.
7. 2 biosynthesis. J. Biol. Chem. 275: 32775-32782.
8. 2 synthesis. Mol. Cell. Biol. 27: 4416-4430.
9. 2 synthase that acts in concert with cyclooxygenase-2. J. Biol. Chem. 275: 32783-32792.
10. 2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2. J. Biol. Chem. 278: 37937-37947.
11. 2 production and alters the gastric prostanoid profile. J. Biol. Chem. 279: 23229-23237.
12. 2 production in the rat adjuvant-induced arthritis model. J. Immunol. 170: 4738-4744.
13. 2 receptors in the pathogenesis of rheumatoid arthritis. J. Clin. Invest. 110: 651-658.
14. Lemos, H. P., R. Grespan, S. M. Vieira, T. M. Cunha, W. A. Verri Jr., K. S. Fernandes, F. O. Souto, I. B. McInnes, S. H. Ferreira, and F. Y. Liew, et al. 2009. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in in- flammation by inhibiting IL-12 and IFNgamma production. Proc. Natl. Acad. Sci. U.S.A. 106: 5954-5959.
15. 2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J. Exp. Med. 206: 535-548.
16. 2 synergistically with interleukin-23 favors human Th17 expansion. Blood 112: 3696-3703.
17. 2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells. J. Immunol. 181: 721-735.
18. 2 exacerbates collagen-induced arthritis in mice through the inflammatory interleukin-23/interleukin-17 axis. Arthritis Rheum. 56: 2608-2619.
19. Kunikata, T., H. Yamane, E. Segi, T. Matsuoka, Y. Sugimoto, S. Tanaka, H. Tanaka, H. Nagai, A. Ichikawa, and S. Narumiya. 2005. Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3. Nat. Immunol. 6: 524-531.
20. 2 on allergic airway responses in the rat. J. Immunol. 169: 3963-3969.
21. Sugimoto, Y., and S. Narumiya. 2007. Prostaglandin E receptors. J. Biol. Chem. 282: 11613-11617.
22. Nagamachi, M., D. Sakata, K. Kabashima, T. Furuyashiki, T. Murata, E. Segi-Nishida, K. Soontrapa, T. Matsuoka, Y. Miyachi, and S. Narumiya. 2007. Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1. J. Exp. Med. 204: 2865-2874.
23. 2 that differentially modulate activation responses. Blood 107: 3243-3250.
24. 2 in normal and asthmatic men. N. Engl. J. Med. 311: 209-213.
25. Allen, I. C., J. M. Hartney, T. M. Coffman, R. B. Penn, J. Wess, and B. H. Koller. 2006. Thromboxane A2 induces airway constriction through an M3 muscarinic acetylcholine receptor-dependent mechanism. Am. J. Physiol. Lung Cell. Mol. Physiol. 290: L526-L533.
26. 2 reinforces Th2 type inflammatory responses of airways to low-dose antigen through bronchial expression of macrophage-derived chemokine. J. Exp. Med. 198: 533-543.
27. Peebles, R. S., Jr., K. Hashimoto, J. D. Morrow, R. Dworski, R. D. Collins, Y. Hashimoto, J. W. Christman, K. H. Kang, K. Jarzecka, J. Furlong, et al. 2002. Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice. Am. J. Respir. Crit. Care Med. 165: 1154-1160.
28. Gavett, S. H., S. L. Madison, P. C. Chulada, P. E. Scarborough, W. Qu, J. E. Boyle, H. F. Tiano, C. A. Lee, R. Langenbach, V. L. Roggli, et al. 1999. Allergic lung responses are increased in prostaglandin H synthase-deficient mice. J. Clin. Invest. 104: 721-732.
29. Gauvreau, G. M., R. M. Watson, and P. M. O'Byrne. 1999. Protective effects of inhaled PGE2 on allergen-induced airway responses and airway inflammation. Am. J. Respir. Crit. Care Med. 159: 31-36.
30. Kowalski, M. L., R. Pawliczak, J. Wozniak, K. Siuda, M. Poniatowska, J. Iwaszkiewicz, T. Kornatowski, and M. A. Kaliner. 2000. Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirinsensitive and aspirin-tolerant patients. Am. J. Respir. Crit. Care Med. 161: 391-398.
31. 4 excretion in aspirin-sensitive asthma. Am. J. Respir. Crit. Care Med. 153: 572-575.
32. Hao, C. M., R. Redha, J. Morrow, and M. D. Breyer. 2002. Peroxisome proliferator-activated receptor d activation promotes cell survival following hypertonic stress. J. Biol. Chem. 277: 21341-21345.
33. Tabuchi, A., M. Mertens, H. Kuppe, A. R. Pries, and W. M. Kuebler. 2008. Intravital microscopy of the murine pulmonary microcirculation. J. Appl. Physiol. 104: 338-346.
34. Sanchez, O., E. Marcos, F. Perros, E. Fadel, L. Tu, M. Humbert, P. Dartevelle, G. Simonneau, S. Adnot, and S. Eddahibi. 2007. Role of endothelium-derived CC chemokine ligand 2 in idiopathic pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 176: 1041-1047.
35. Hansmann, G., V. A. de Jesus Perez, T. P. Alastalo, C. M. Alvira, C. Guignabert, J. M. Bekker, S. Schellong, T. Urashima, L. Wang, and N. W. Morrell, et al. 2008. An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension. J. Clin. Invest. 118: 1846-1857.
36. Liu, M. C., W. C. Hubbard, D. Proud, B. A. Stealey, S. J. Galli, A. Kagey-Sobotka, E. R. Bleecker, and L. M. Lichtenstein. 1991. Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes. Am. Rev. Respir. Dis. 144: 51-58.
37. Barrett, N. A., A. Maekawa, O. M. Rahman, K. F. Austen, and Y. Kanaoka. 2009. Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells. J. Immunol. 182: 1119-1128.
38. Johnson, J. R., R. E. Wiley, R. Fattouh, F. K. Swirski, B. U. Gajewska, A. J. Coyle, J. C. Gutierrez-Ramos, R. Ellis, M. D. Inman, and M. Jordana. 2004. Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling. Am. J. Respir. Crit. Care Med. 169: 378-385.
39. Jaffar, Z., M. E. Ferrini, M. C. Buford, G. A. Fitzgerald, and K. Roberts. 2007. Prostaglandin I2-IP signaling blocks allergic pulmonary inflammation by preventing recruitment of CD4+ Th2 cells into the airways in a mouse model of asthma. J. Immunol. 179: 6193-6203.
40. Hammad, H., M. Kool, T. Soullié, S. Narumiya, F. Trottein, H. C. Hoogsteden, and B. N. Lambrecht. 2007. Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J. Exp. Med. 204: 357-367.
41. Wang, M., A. M. Zukas, Y. Hui, E. Ricciotti, E. Puré, and G. A. FitzGerald. 2006. Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis. Proc. Natl. Acad. Sci. U.S.A. 103: 14507-14512.
42. 2 that blocks T cell proliferation and promotes a Th2-like response. J. Immunol. 178: 2065-2074.
43. Staples, K. J., M. Bergmann, K. Tomita, M. D. Houslay, I. McPhee, P. J. Barnes, M. A. Giembycz, and R. Newton. 2001. Adenosine 3′,5′-cyclic monophosphate (cAMP)-dependent inhibition of IL-5 from human T lymphocytes is not mediated by the cAMP-dependent protein kinase A. J. Immunol. 167: 2074-2080.
44. 2 inhibits eosinophil trafficking through E-prostanoid 2 receptors. J. Immunol. 181: 7273-7283.
45. Herrerias, A., R. Torres, M. Serra, A. Marco, J. Roca-Ferrer, C. Picado, and F. de Mora. 2009. Subcutaneous prostaglandin E(2) restrains airway mast cell activity in vivo and reduces lung eosinophilia and Th(2) cytokine overproduction in house dust mite-sensitive mice. Int. Arch. Allergy Immunol. 149: 323-332.
46. Törmänen, K. R., L. Uller, C. G. Persson, and J. S. Erjefält. 2005. Allergen exposure of mouse airways evokes remodeling of both bronchi and large pulmonary vessels. Am. J. Respir. Crit. Care Med. 171: 19-25.
47. Rydell-Törmänen, K., J. R. Johnson, R. Fattouh, M. Jordana, and J. S. Erjefält. 2008. Induction of vascular remodeling in the lung by chronic house dust mite exposure. Am. J. Respir. Cell Mol. Biol. 39: 61-67.
48. Daley, E., C. Emson, C. Guignabert, R. de Waal Malefyt, J. Louten, V. P. Kurup, C. Hogaboam, L. Taraseviciene-Stewart, N. F. Voelkel, M. Rabinovitch, et al. 2008. Pulmonary arterial remodeling induced by a Th2 immune response. J. Exp. Med. 205: 361-372.