-
1
-
-
0029657597
-
Paclitaxel (TAXOL(R)) inhibits motility of paclitaxel-resistant human ovarian carcinoma cells
-
1:CAS:528:DyaK28XmsVOlu7o%3D
-
Belotti D, Rieppi M, Nicoletti MI (1996) Paclitaxel (TAXOL(R)) inhibits motility of paclitaxel-resistant human ovarian carcinoma cells. Clin Cancer Res 2:1725-1730
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1725-1730
-
-
Belotti, D.1
Rieppi, M.2
Nicoletti, M.I.3
-
2
-
-
84873694439
-
N-acetylcysteine potentiates doxorubicin-induced ATM and p53 activation in ovarian cancer cells
-
1:CAS:528:DC%2BC3sXhsVWnt7Y%3D
-
Brum G et al (2013) N-acetylcysteine potentiates doxorubicin-induced ATM and p53 activation in ovarian cancer cells. Int J Oncol 42:211-219
-
(2013)
Int J Oncol
, vol.42
, pp. 211-219
-
-
Brum, G.1
-
3
-
-
33749267293
-
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs
-
10.1016/j.pharmthera.2006.04.009 1:CAS:528:DC%2BD28XhtVGjt7jP
-
Cascorbi I (2006) Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs. Pharmacol Ther 112:457-473
-
(2006)
Pharmacol Ther
, vol.112
, pp. 457-473
-
-
Cascorbi, I.1
-
4
-
-
47549115467
-
Mitochondrial transmembrane potential and reactive oxygen species generation regulate the enhanced effect of CCCP on TRAIL-induced SNU-638 cell apoptosis
-
10.1292/jvms.70.537 1:CAS:528:DC%2BD1cXpt1ehurs%3D
-
Chaudhari AA et al (2008) Mitochondrial transmembrane potential and reactive oxygen species generation regulate the enhanced effect of CCCP on TRAIL-induced SNU-638 cell apoptosis. J Vet Med Sci 70:537-542
-
(2008)
J Vet Med Sci
, vol.70
, pp. 537-542
-
-
Chaudhari, A.A.1
-
5
-
-
58749116202
-
Hexane/Ethanol of Glycyrrhiza Uralensis Licorice suppresses doxorubicin-induced apoptosis in H9c2 rat cardiac myoblasts
-
10.3181/0807-RM-221 1:CAS:528:DC%2BD1cXhsVOjtLjF
-
Choi HJ et al (2008) Hexane/Ethanol of Glycyrrhiza Uralensis Licorice suppresses doxorubicin-induced apoptosis in H9c2 rat cardiac myoblasts. Exp Biol Med 233:1554-1560
-
(2008)
Exp Biol Med
, vol.233
, pp. 1554-1560
-
-
Choi, H.J.1
-
6
-
-
43949138899
-
Mechanisms and strategies to overcome chemotherapy resistance in metastatic breast cancer
-
10.1016/j.ctrv.2008.01.007 1:CAS:528:DC%2BD1cXmtlWiurY%3D
-
Coley HM (2008) Mechanisms and strategies to overcome chemotherapy resistance in metastatic breast cancer. Cancer Treat Rev 34:378-390
-
(2008)
Cancer Treat Rev
, vol.34
, pp. 378-390
-
-
Coley, H.M.1
-
7
-
-
84874438271
-
The role of proton dynamics in the development and maintenance o multidrug resistance in cancer
-
10.1016/j.bbadis.2013.01.020
-
Daniel C et al (2013) The role of proton dynamics in the development and maintenance o multidrug resistance in cancer. Biochim Biophys Acta. doi: 10.1016/j.bbadis.2013.01.020
-
(2013)
Biochim Biophys Acta
-
-
Daniel, C.1
-
8
-
-
20244370600
-
Intrinsic chemotherapy resistance to the tubulin-binding antimitotic agents in renal cell carcinoma
-
10.1002/ijc.20816 1:CAS:528:DC%2BD2MXjsleju7w%3D
-
Ferguson R, Jackson S, Stanley A, Joyce A, Harnden P, Morrison E, Patel P, Phillips R, Selby P, Banks R (2005) Intrinsic chemotherapy resistance to the tubulin-binding antimitotic agents in renal cell carcinoma. Int J Cancer 115:155-163
-
(2005)
Int J Cancer
, vol.115
, pp. 155-163
-
-
Ferguson, R.1
Jackson, S.2
Stanley, A.3
Joyce, A.4
Harnden, P.5
Morrison, E.6
Patel, P.7
Phillips, R.8
Selby, P.9
Banks, R.10
-
9
-
-
34548317034
-
Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer
-
10.1038/sj.bjc.6603922 1:CAS:528:DC%2BD2sXpsF2ksLY%3D
-
Gatenby RA et al (2007) Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer. Br J Cancer 97:646-653
-
(2007)
Br J Cancer
, vol.97
, pp. 646-653
-
-
Gatenby, R.A.1
-
10
-
-
34547124566
-
Hypoxia and adaptive landscapes in the evolution of carcinogenesis
-
10.1007/s10555-007-9065-z 1:CAS:528:DC%2BD2sXotFWrtLk%3D
-
Gillies RJ, Gatenby RA (2007) Hypoxia and adaptive landscapes in the evolution of carcinogenesis. Cancer Metastasis Rev 26:311-317
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 311-317
-
-
Gillies, R.J.1
Gatenby, R.A.2
-
11
-
-
16644376266
-
PH Imaging: A review of Ph measurement methods and applications in cancers
-
Gillies RJ et al (2004) pH Imaging: a review of Ph measurement methods and applications in cancers. Eng Med Biol Mag 2:57-64
-
(2004)
Eng Med Biol Mag
, vol.2
, pp. 57-64
-
-
Gillies, R.J.1
-
12
-
-
46749121459
-
Causes and consequences of increased glucose metabolism of cancers
-
10.2967/jnumed.107.047258
-
Gillies RJ, Robey I, Gatenby RA (2008) Causes and consequences of increased glucose metabolism of cancers. J Nucl Med 49:24-42
-
(2008)
J Nucl Med
, vol.49
, pp. 24-42
-
-
Gillies, R.J.1
Robey, I.2
Gatenby, R.A.3
-
13
-
-
0036176510
-
Mechanisms of cancer drug resistance
-
10.1146/annurev.med.53.082901.103929 1:CAS:528:DC%2BD38Xitl2mtLo%3D
-
Gottesman MM (2002) Mechanisms of cancer drug resistance. Annu Rev Med 53:615-627
-
(2002)
Annu Rev Med
, vol.53
, pp. 615-627
-
-
Gottesman, M.M.1
-
14
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
10.1038/nrc706 1:CAS:528:DC%2BD38XhvF2jtL8%3D
-
Gottesman MM, Fojo T, Bates SE (2002) Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2:48-58
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
15
-
-
84864402951
-
Anticancer agents that counteract tumor glycolysis
-
1:CAS:528:DC%2BC38Xot1KgtLg%3D
-
Granchi C, Minutolo F (2012) Anticancer agents that counteract tumor glycolysis. Chem Med Chem 7:1318-1350
-
(2012)
Chem Med Chem
, vol.7
, pp. 1318-1350
-
-
Granchi, C.1
Minutolo, F.2
-
16
-
-
0027207761
-
Paclitaxel: A new antineoplastic agent for refractory ovarian cancer
-
1:CAS:528:DyaK3sXlsFWnu74%3D
-
Gregory RE, DeLisa AF (1993) Paclitaxel: a new antineoplastic agent for refractory ovarian cancer. Clin Pharm 12:401-415
-
(1993)
Clin Pharm
, vol.12
, pp. 401-415
-
-
Gregory, R.E.1
Delisa, A.F.2
-
17
-
-
70349176240
-
Is resistance useless? Multidrug resistance and collateral sensivity
-
10.1016/j.tips.2009.07.003 1:CAS:528:DC%2BD1MXhtFyqtb3J
-
Hall M, Handley M, Gottesman M (2009) Is resistance useless? Multidrug resistance and collateral sensivity. Trends Pharmacol Sci 30:546-556
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 546-556
-
-
Hall, M.1
Handley, M.2
Gottesman, M.3
-
18
-
-
80052242132
-
Targeting cancer metabolism: A therapeutic window opens
-
10.1038/nrd3504
-
Heiden V, Matthew G (2011) Targeting cancer metabolism: a therapeutic window opens. Nat Rev Drug Discov 10:671-684
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 671-684
-
-
Heiden, V.1
Matthew, G.2
-
19
-
-
0030000299
-
Interaction of ionizing radiation with paclitaxel (taxol) and docetaxel (taxotere) in Hela and SQ20B cells
-
1:CAS:528:DyaK28Xitlyks7k%3D
-
Hennequin C, Giocanti N, Favaudon V (1996) Interaction of ionizing radiation with paclitaxel (taxol) and docetaxel (taxotere) in Hela and SQ20B cells. Cancer Res 56:1842-1850
-
(1996)
Cancer Res
, vol.56
, pp. 1842-1850
-
-
Hennequin, C.1
Giocanti, N.2
Favaudon, V.3
-
20
-
-
20244388917
-
Cellular pH regulators: Potentially promising molecular targets for cancer chemotherapy
-
10.1016/S0305-7372(03)00106-3 1:CAS:528:DC%2BD3sXosVygt7g%3D
-
Izumi H et al (2003) Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy. Cancer Treat Rev 29:541-549
-
(2003)
Cancer Treat Rev
, vol.29
, pp. 541-549
-
-
Izumi, H.1
-
21
-
-
0034104453
-
Resistance mechanisms associated with altered intracellular distribution of anticancer agents
-
10.1016/S0163-7258(99)00073-X 1:CAS:528:DC%2BD3cXitVWjs7Y%3D
-
Larsen A, Escargueil EA, Skladanowski A (2000) Resistance mechanisms associated with altered intracellular distribution of anticancer agents. Pharmacol Ther 85:217-229
-
(2000)
Pharmacol Ther
, vol.85
, pp. 217-229
-
-
Larsen, A.1
Escargueil, E.A.2
Skladanowski, A.3
-
22
-
-
0442313668
-
Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions
-
10.1007/s00280-003-0724-7 1:CAS:528:DC%2BD3sXhtVSjsLfK
-
Maher JC, Krishan A, Lampidis TJ (2004) Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions. Cancer Chemother Pharmacol 53:116-22
-
(2004)
Cancer Chemother Pharmacol
, vol.53
, pp. 116-122
-
-
Maher, J.C.1
Krishan, A.2
Lampidis, T.J.3
-
23
-
-
33847367741
-
Energy metabolism in tumor cells
-
10.1111/j.1742-4658.2007.05686.x
-
Moreno-Sánchez R et al (2007) Energy metabolism in tumor cells. FEBS J 274:1393-1418
-
(2007)
FEBS J
, vol.274
, pp. 1393-1418
-
-
Moreno-Sánchez, R.1
-
24
-
-
84934441721
-
Cell migration and invasion assays
-
10.1007/978-1-61779-080-5-27 1:CAS:528:DC%2BC3MXntVyqurc%3D
-
Moutasim KA, Nystrom ML, Thomas GJ (2011) Cell migration and invasion assays. Methods Mol Biol 731:333-43
-
(2011)
Methods Mol Biol
, vol.731
, pp. 333-343
-
-
Moutasim, K.A.1
Nystrom, M.L.2
Thomas, G.J.3
-
25
-
-
80053563164
-
Interfering with pH regulation in tumours as a therapeutic strategy
-
10.1038/nrd3554 1:CAS:528:DC%2BC3MXhtFOlsL7L
-
Neri D, Supuran CT (2011) Interfering with pH regulation in tumours as a therapeutic strategy. Discovery Nat Rev Drug Discov 10:767-777
-
(2011)
Discovery Nat Rev Drug Discov
, vol.10
, pp. 767-777
-
-
Neri, D.1
Supuran, C.T.2
-
26
-
-
78650722178
-
Anticancer drugs that target metabolism: Is dichloroacetate the new paradigm?
-
10.1002/ijc.25728 1:CAS:528:DC%2BC3cXhs1ajs7nE
-
Papandreou I, Goliasova T, Denko NC (2011) Anticancer drugs that target metabolism: is dichloroacetate the new paradigm? Int J Cancer 128:1001-1008
-
(2011)
Int J Cancer
, vol.128
, pp. 1001-1008
-
-
Papandreou, I.1
Goliasova, T.2
Denko, N.C.3
-
27
-
-
84858708932
-
Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate
-
10.1007/s10863-012-9418-3
-
Queirós O et al (2012) Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate. J Bioenerg Biomembr 44:141-153
-
(2012)
J Bioenerg Biomembr
, vol.44
, pp. 141-153
-
-
Queirós, O.1
-
28
-
-
0034143570
-
PH and drug resistance in tumors
-
10.1054/drup.2000.0119 1:CAS:528:DC%2BD3cXjsV2mt7k%3D
-
Raghunand N, Gillies RJ (2000) pH and drug resistance in tumors. Drug Resist Updat 3:39-47
-
(2000)
Drug Resist Updat
, vol.3
, pp. 39-47
-
-
Raghunand, N.1
Gillies, R.J.2
-
29
-
-
79958081523
-
Bicarbonate and dicholoroacetate: Evaluating pH altering therapies in a mouse model for metastatic breast cancer
-
10.1186/1471-2407-11-235
-
Robey IF, Martin NK (2011) Bicarbonate and dicholoroacetate: evaluating pH altering therapies in a mouse model for metastatic breast cancer. BMC Cancer 11:1-10
-
(2011)
BMC Cancer
, vol.11
, pp. 1-10
-
-
Robey, I.F.1
Martin, N.K.2
-
30
-
-
79958191830
-
Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
-
10.1016/j.drup.2011.03.001 1:CAS:528:DC%2BC3MXntlGktL0%3D
-
Rohwer N, Cramer T (2011) Hypoxia-mediated drug resistance: novel insights on the functional interaction of HIFs and cell death pathways. Drug Resist Updat 14:191-201
-
(2011)
Drug Resist Updat
, vol.14
, pp. 191-201
-
-
Rohwer, N.1
Cramer, T.2
-
31
-
-
78049487868
-
Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC
-
10.1002/ijc.25499 1:CAS:528:DC%2BC3cXhsVGhtrfP
-
Stockwin LH et al (2010) Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC. Int J Cancer 127:2510-2519
-
(2010)
Int J Cancer
, vol.127
, pp. 2510-2519
-
-
Stockwin, L.H.1
-
32
-
-
34447547148
-
Regulation of tumor pH and the role of carbonic anhydrase 9
-
10.1007/s10555-007-9064-0 1:CAS:528:DC%2BD2sXotFWrtLc%3D
-
Swietach P, Vaughan-Jones RD, Harris AL (2007) Regulation of tumor pH and the role of carbonic anhydrase 9. Cancer Metastasis Rev 26:299-310
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 299-310
-
-
Swietach, P.1
Vaughan-Jones, R.D.2
Harris, A.L.3
-
33
-
-
33646428345
-
Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs
-
10.1593/neo.05697 1:CAS:528:DC%2BD28XovVKltbY%3D
-
Thews O et al (2006) Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs. Neoplasia 8:143-152
-
(2006)
Neoplasia
, vol.8
, pp. 143-152
-
-
Thews, O.1
-
34
-
-
79953291925
-
Synergistic antitumor effect of dichloroacetate in combination with 5-Fluorouracil in colorectal cancer
-
10.1155/2011/740564
-
Tong J et al (2011) Synergistic antitumor effect of dichloroacetate in combination with 5-Fluorouracil in colorectal cancer. J Biomed Biotechnol 2011:1-7
-
(2011)
J Biomed Biotechnol
, vol.2011
, pp. 1-7
-
-
Tong, J.1
-
35
-
-
12444279265
-
On the origin of cancer cells
-
10.1126/science.123.3191.309 1:STN:280:DyaG28%2FltV2ktQ%3D%3D
-
Warburg O (1956) On the origin of cancer cells. Science 123:309-314
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
36
-
-
74949117256
-
Glycolytic pyruvate regulates P-Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state
-
1:CAS:528:DC%2BC3cXhtVSmtLg%3D
-
Wartenberg M et al (2010) Glycolytic pyruvate regulates P-Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state. J Cell Biochem 109:434-446
-
(2010)
J Cell Biochem
, vol.109
, pp. 434-446
-
-
Wartenberg, M.1
-
37
-
-
81155159685
-
Dysregulated pH: A perfect storm for cancer progression
-
10.1038/nrc3110 1:CAS:528:DC%2BC3MXpvF2is7k%3D
-
Webb BA et al (2011) Dysregulated pH: a perfect storm for cancer progression. Nat Rev Cancer 11:671-677
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 671-677
-
-
Webb, B.A.1
-
38
-
-
79958093404
-
Hypoxia-induced metabolic shifts in cancer: Moving beyond the Warburg effect
-
10.1016/j.biocel.2010.08.009 1:CAS:528:DC%2BC3MXntV2msbc%3D
-
Weljie AM, Jirik FR (2011) Hypoxia-induced metabolic shifts in cancer: moving beyond the Warburg effect. Int J Biochem Cell Biol 43:981-989
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 981-989
-
-
Weljie, A.M.1
Jirik, F.R.2
-
39
-
-
0033609365
-
An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: Implications for clonal selection during colorectal carcinogenesis
-
10.1038/sj.onc.1202660 1:CAS:528:DyaK1MXjvVeqsrg%3D
-
Williams AC, Collard TJ, Paraskeva C (1999) An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: implications for clonal selection during colorectal carcinogenesis. Oncogene 18:3199-3204
-
(1999)
Oncogene
, vol.18
, pp. 3199-3204
-
-
Williams, A.C.1
Collard, T.J.2
Paraskeva, C.3
-
40
-
-
0034662615
-
Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH
-
1:CAS:528:DC%2BD3cXmsVaiurY%3D
-
Yuan J, Narayanan L, Rockwell S (2000) Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH. Cancer Res 60:4372-4376
-
(2000)
Cancer Res
, vol.60
, pp. 4372-4376
-
-
Yuan, J.1
Narayanan, L.2
Rockwell, S.3
-
41
-
-
1942484442
-
Phorbol myristate induces apoptosis of taxol-resistant sarcoma cells in vitro
-
10.1016/j.ejphar.2004.02.027 1:CAS:528:DC%2BD2cXisl2rs74%3D
-
Zong ZP et al (2004) Phorbol myristate induces apoptosis of taxol-resistant sarcoma cells in vitro. Eur J Pharmacol 489(1-2):3-11
-
(2004)
Eur J Pharmacol
, vol.489
, Issue.1-2
, pp. 3-11
-
-
Zong, Z.P.1
|