Glycolytic pyruvate regulates P-glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state

Journal of Cellular Biochemistry

Volumn 109, Issue 2, 2010, Pages 434-446

  Wartenberg, Maria ^a   Richter, Madeleine ^a   Datchev, André ^a   Günther, Sebastian ^b   Milosevic, Nada ^c   Bekhite, Mohamed M ^a   Figulla, Hans Reiner ^a   Aran, Josep M ^d   Pétriz, Jordi ^d   Sauer, Heinrich ^c  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

^d HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

Glycolysis; Multidrug resistance; P glycoprotein; Reactive oxygen species

Indexed keywords

DEOXYGLUCOSE; DOXORUBICIN; EBSELEN; GLYCOPROTEIN P; IODOACETIC ACID; LACTIC ACID; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; GLIOMA CELL; GLYCOLYSIS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MULTICELLULAR SPHEROID; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROTEIN EXPRESSION; UTERINE CERVIX CARCINOMA;

EID: 74949117256     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22422     Document Type: Article

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