Paclitaxel (Taxol®) inhibits motility of paclitaxel-resistant human ovarian carcinoma cells

Clinical Cancer Research

Volumn 2, Issue 10, 1996, Pages 1725-1730

  Belotti, Dorina ^a   Rieppi, Monica ^a   Nicoletti, Maria Ines ^a   Casazza, Anna Maria ^b   Fojo, Tito ^c   Taraboletti, Giulia ^a   Giavazzi, Ratfaella ^a  

^a MARIO NEGRI INST PHARMACOL RES   (Italy)

^b BRISTOL MYERS SQUIBB   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PACLITAXEL; ANTINEOPLASTIC AGENT;

ARTICLE; CELL MOTILITY; DRUG RESISTANCE; HUMAN; HUMAN CELL; OVARY CARCINOMA; PRIORITY JOURNAL; TUMOR CELL LINE; CELL ADHESION; CELL CULTURE; CELL DIVISION; CELL MOTION; DRUG EFFECT; FEMALE; OVARY TUMOR; PATHOLOGY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL ADHESION; CELL DIVISION; CELL MOVEMENT; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; OVARIAN NEOPLASMS; PACLITAXEL; TUMOR CELLS, CULTURED;

EID: 0029657597     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Rowinsky, E. K., and Donehower, R. C. Paclitaxel (Taxol). N. Engl. J. Med, 332: 1004-1014, 1995.
2. Jordan, M. A., Toso, R. J., Thrower, D., and Wilson, L. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentration. Proc. Natl. Acad. Sci. USA, 90: 9552-9556, 1993.
3. Mareel, M. M., and De Mets, M. Effect of microtubule inhibitors on invasion and on related activities of tumor cells. Int Rev. Cytol., 90: 125-168, 1984.
4. Schiff, P. B., and Horwitz, S. B. Taxol stabilizes microtubules in mouse fibroblast cells. Proc. Natl. Acad. Sci. USA, 77: 1561-1565, 1980.
5. Donehower, R. C., Rowinsky, E. K., Grochow, L. B., Longnecker, S. M., and Ettinger, D. S. Phase I trial of taxol in patients with advanced cancer. Cancer Treat. Rep., 71: 1171-1177, 1987.
6. Caldas, C., and McGuire, W. P, III. Taxol in epithelial ovarian cancer Monogr Natl. Cancer Inst., 15: 155-159, 1993.
7. McGuire, W. P., Rowinsky, E. K., Rosenshein, N. B., Grumbine, F C., Ettinger, D. S., Armstrong, D. K., and Donehower, R. C. Taxol: a unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms. Ann. Intern. Med., 111: 273-279, 1989.
8. Einzig, A. I., Wiernik. P. H., Sasloff, J., Runowicz, C. D., and Goldberg, G. L. Phase II study and long-term follow-up of patients treated with Taxol for advanced ovarian adenocarcinoma. J. Clin. Oncol., 10: 1748-1753, 1992.
9. Cannistra, S. A. Cancer of the ovary. N. Engl. J. Med., 329: 1550-1559, 1993.
10. Cannistra, S. A., Kansas, G. S., Niloff, J., DeFranzo, B., Kim, Y., and Ottensmeier, C. Binding of ovarian cancer cells to peritoneal mesothelium in vitro is partly mediated by CD44H. Cancer Res., 53: 3830-3838, 1993.
11. Liebman, J. M., Burbelo, P. D., Yamada, Y., Fridman, R., and Kleinman, H. K. Altered expression of basement-membrane components and collagenases in ascitic xenografts of OVCAR-3 ovarian cancer cells. Int. J. Cancer, 55: 102-109, 1993.
12. Massazza, G, Tomasoni, A., Lucchini, V., Allavena, P., Erba, E., Colombo, N., Mantovani, A, D'Incalci, M., Mangioni, C., and Giavazzi, R. Intraperitoneal and subcutaneous xenografts of human ovarian carcinoma in nude mice and their potential in experimental therapy. Int. J. Cancer, 44: 494-500, 1989.
13. Taraboletti, G., Belotti, D., Dejana, E., Mantovani, A., and Giavazzi, R. Endothelial cell migration and invasiveness are induced by soluble factor produced by murine endothelioma cells transformed by polyoma virus middle T oncogene. Cancer Res., 53: 3812-3816, 1993.
14. Taraboletti, G., Belotti, D., Giavazzi, R., Sobel, M. E., and Castronovo, V. Enhancement of metastatic potential of murine and human melanoma cells by laminin receptor peptide G: attachment of cancer cells to subendothelial matrix as a pathway for hematogenous metastasis. J. Natl. Cancer Inst., 55; 235-240, 1993.
15. Stracke, M. L., Soroush, M., Liotta, L A , and Schiffmann, E. Cytoskeletal agents inhibit motility and adherence of human tumor cells. Kidney Int., 43: 151-157, 1993.
16. Stearns, M. E., and Wang, M. Taxol blocks processes essential for prostate tumor cell (PC-3 ML) invasion and metastases. Cancer Res., 52: 3776-3781, 1992.
17. Verschueren, H., Dewit, J , De Braekeleer, J., Schirrmacher, V., and De Baetselier, P. Motility and invasive potency of murine T-lymphoma cells: effect of microtubule inhibitors. Cell Biot Int., 18: 11-19, 1994.
18. Rowinsky, E. K., Cazenave, L. A., and Donehower, R. C. Taxol: a novel investigational antimicrotubule agent J. Natl. Cancer Inst., 82: 1247-1259, 1990.
19. Singer, S. J., and Kupfer, A. The directed migration of eukaryotic cells. Annu. Rev. Cell Biol., 2: 337-365, 1986.