메뉴 건너뛰기




Volumn , Issue , 2012, Pages 214-229

Vitamin E

Author keywords

"antioxidant network" and aqueous antioxidants and cellular metabolism; Tocopherol, a vitamin E form required for humans; Tocopherol, acting as peroxyl, alkoxyl radical scavenger in lipid environments; Vitamin E and C, and benefits for humans under oxidative stress; Vitamin E antioxidant, chain breaking and free radical prevention; Vitamin E bioavailability varying, as food fortificants, and as supplements; Vitamin E intake needed, what is adequate, and for what function, to be defined; Vitamin E uniqueness in human nutrition, as antioxidants; Vitamin E, Food and Nutrition Board, the UL tocopherol, 1000 mg for adults

Indexed keywords


EID: 84885485809     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781119946045.ch14     Document Type: Chapter
Times cited : (24)

References (108)
  • 1
    • 0034800655 scopus 로고    scopus 로고
    • Arch Ophthalmol
    • Age-Related Eye Disease Study Research Group, A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS Report No. 8
    • Age-Related Eye Disease Study Research Group (2001) A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS Report No. 8. Arch Ophthalmol 119, 1417-1436.
    • (2001) , vol.119 , pp. 1417-1436
  • 2
    • 0030773771 scopus 로고    scopus 로고
    • Alpha-tocopherol transfer protein stimulates the secretion of alpha-tocopherol from a cultured liver cell line through a brefeldin A-insensitive pathway
    • Arita, M., Nomura, K., Arai, H., et al. (1997) Alpha-tocopherol transfer protein stimulates the secretion of alpha-tocopherol from a cultured liver cell line through a brefeldin A-insensitive pathway. Proc Natl Acad Sci USA 94, 12437-12441.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12437-12441
    • Arita, M.1    Nomura, K.2    Arai, H.3
  • 3
    • 11144244985 scopus 로고    scopus 로고
    • Vitamin E intake and risk of amyotrophic lateral sclerosis
    • Ascherio, A., Weisskopf, M.G., O'Reilly E, J., et al. (2005) Vitamin E intake and risk of amyotrophic lateral sclerosis. Ann Neurol 57, 104-110.
    • (2005) Ann Neurol , vol.57 , pp. 104-110
    • Ascherio, A.1    Weisskopf, M.G.2    O'Reilly, E.J.3
  • 4
    • 4344653391 scopus 로고    scopus 로고
    • Regulation of gene expression by alpha-tocopherol
    • Azzi, A., Gysin, R., Kempna, P., et al. (2004) Regulation of gene expression by alpha-tocopherol. Biol Chem 385, 585-591.
    • (2004) Biol Chem , vol.385 , pp. 585-591
    • Azzi, A.1    Gysin, R.2    Kempna, P.3
  • 5
    • 77955985049 scopus 로고    scopus 로고
    • Combined vitamin C and vitamin E deficiency worsens early atherosclerosis in apolipoprotein E-deficient mice
    • Babaev, V.R., Li, L., Shah, S., et al. (2010) Combined vitamin C and vitamin E deficiency worsens early atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 30, 1751-1757.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1751-1757
    • Babaev, V.R.1    Li, L.2    Shah, S.3
  • 6
    • 0027514838 scopus 로고
    • Localization of Friedreich ataxia phenotype with selective vitamin E defi-ciency to chromosome 8q by homozygosity mapping
    • Ben Hamida, C., Doerflinger, N., Belal, S., et al. (1993) Localization of Friedreich ataxia phenotype with selective vitamin E defi-ciency to chromosome 8q by homozygosity mapping. Nature Genet 5, 195-200.
    • (1993) Nature Genet , vol.5 , pp. 195-200
    • Hamida, B.C.1    Doerflinger, N.2    Belal, S.3
  • 7
    • 0027430101 scopus 로고
    • Friedreich's ataxia phenotype not linked to chromosome 9 and associated with selective autosomal recessive vitamin E deficiency in two inbred Tunisian families
    • Ben Hamida, M., Bilal, S., Sirugo, G., et al. (1993) Friedreich's ataxia phenotype not linked to chromosome 9 and associated with selective autosomal recessive vitamin E deficiency in two inbred Tunisian families. Neurology 43, 2179-2183.
    • (1993) Neurology , vol.43 , pp. 2179-2183
    • Hamida, B.M.1    Bilal, S.2    Sirugo, G.3
  • 8
    • 62149086225 scopus 로고    scopus 로고
    • Bayesian model averaging in meta-analysis: vitamin E supplementation and mortality
    • Berry, D., Wathen, J.K., and Newell, M. (2009) Bayesian model averaging in meta-analysis: vitamin E supplementation and mortality. Clin Trials 6, 28-41.
    • (2009) Clin Trials , vol.6 , pp. 28-41
    • Berry, D.1    Wathen, J.K.2    Newell, M.3
  • 9
    • 79952048150 scopus 로고    scopus 로고
    • Reexamination of a meta-analysis of the effect of antioxidant supplementation on mortality and health in randomized trials
    • Biesalski, H.K., Grune, T., Tinz, J., et al. (2010) Reexamination of a meta-analysis of the effect of antioxidant supplementation on mortality and health in randomized trials. Nutrients 2, 929-949.
    • (2010) Nutrients , vol.2 , pp. 929-949
    • Biesalski, H.K.1    Grune, T.2    Tinz, J.3
  • 10
    • 33847378451 scopus 로고    scopus 로고
    • Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis
    • Bjelakovic, G., Nikolova, D., Gluud, L.L., et al. (2007) Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 297, 842-857.
    • (2007) JAMA , vol.297 , pp. 842-857
    • Bjelakovic, G.1    Nikolova, D.2    Gluud, L.L.3
  • 11
    • 77956625356 scopus 로고    scopus 로고
    • Evidence-based criteria in the nutritional context
    • Blumberg, J., Heaney, R.P., Huncharek, M., et al. (2010) Evidence-based criteria in the nutritional context. Nutr Rev 68, 478-484.
    • (2010) Nutr Rev , vol.68 , pp. 478-484
    • Blumberg, J.1    Heaney, R.P.2    Huncharek, M.3
  • 12
    • 0033037413 scopus 로고    scopus 로고
    • Vitamin E: function and metabolism
    • Brigelius-Flohé, R. and Traber, M.G. (1999) Vitamin E: function and metabolism. FASEB J 13, 1145-1155.
    • (1999) FASEB J , vol.13 , pp. 1145-1155
    • Brigelius-Flohé, R.1    Traber, M.G.2
  • 13
    • 0035969564 scopus 로고    scopus 로고
    • Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
    • Brown, B.G., Zhao, X.Q., Chait, A., et al. (2001) Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 345, 1583-1592.
    • (2001) N Engl J Med , vol.345 , pp. 1583-1592
    • Brown, B.G.1    Zhao, X.Q.2    Chait, A.3
  • 14
    • 31644451870 scopus 로고    scopus 로고
    • Faster vitamin E disappearance in smokers is normalized by vitamin C supplementation
    • Bruno, R.S., Leonard, S.W., Atkinson, J.K., et al. (2006a) Faster vitamin E disappearance in smokers is normalized by vitamin C supplementation. Free Radic Biol Med 40, 689-697.
    • (2006) Free Radic Biol Med , vol.40 , pp. 689-697
    • Bruno, R.S.1    Leonard, S.W.2    Atkinson, J.K.3
  • 15
    • 33644871107 scopus 로고    scopus 로고
    • Human vitamin E requirements assessed with the use of apples fortified with deuterium-labeled α-tocopheryl acetate
    • Bruno, R.S., Leonard, S.W., Park, S.-I., et al. (2006b) Human vitamin E requirements assessed with the use of apples fortified with deuterium-labeled α-tocopheryl acetate. Am J Clin Nutr 83, 299-304.
    • (2006) Am J Clin Nutr , vol.83 , pp. 299-304
    • Bruno, R.S.1    Leonard, S.W.2    Park, S.-I.3
  • 16
    • 13744249872 scopus 로고    scopus 로고
    • α-Tocopherol disappearance is faster in cigarette smokers and is inversely related to their ascorbic acid status
    • Bruno, R.S., Ramakrishnan, R., Montine, T.J., et al. (2005) α-Tocopherol disappearance is faster in cigarette smokers and is inversely related to their ascorbic acid status. Am J Clin Nutr 81, 95-103.
    • (2005) Am J Clin Nutr , vol.81 , pp. 95-103
    • Bruno, R.S.1    Ramakrishnan, R.2    Montine, T.J.3
  • 17
    • 0027251053 scopus 로고
    • The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate
    • Buettner, G.R. (1993) The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. Arch Biochem Biophys 300, 535-543.
    • (1993) Arch Biochem Biophys , vol.300 , pp. 535-543
    • Buettner, G.R.1
  • 18
    • 33646762858 scopus 로고    scopus 로고
    • A combined deficiency of vitamins E and C causes severe central nervous system damage in guinea pigs
    • Burk, R.F., Christensen, J.M., Maguire, M.J., et al. (2006) A combined deficiency of vitamins E and C causes severe central nervous system damage in guinea pigs. J Nutr 136, 1576-1581.
    • (2006) J Nutr , vol.136 , pp. 1576-1581
    • Burk, R.F.1    Christensen, J.M.2    Maguire, M.J.3
  • 19
    • 0031976862 scopus 로고    scopus 로고
    • Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E
    • Burton, G.W., Traber, M.G., Acuff, R.V., et al. (1998) Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E. Am J Clin Nutr 67, 669-684.
    • (1998) Am J Clin Nutr , vol.67 , pp. 669-684
    • Burton, G.W.1    Traber, M.G.2    Acuff, R.V.3
  • 20
    • 77953257870 scopus 로고    scopus 로고
    • Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease
    • Butterfield, D.A., Bader Lange, M.L., and Sultana, R. (2010) Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease. Biochim Biophys Acta 1801, 924-929.
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 924-929
    • Butterfield, D.A.1    Lange, B.M.L.2    Sultana, R.3
  • 21
    • 78651288315 scopus 로고    scopus 로고
    • Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency
    • Cahill, L.E. and El-Sohemy, A. (2010) Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency. Am J Clin Nutr 92, 1494-1500.
    • (2010) Am J Clin Nutr , vol.92 , pp. 1494-1500
    • Cahill, L.E.1    El-Sohemy, A.2
  • 22
    • 0028980408 scopus 로고
    • Biokinetics in humans of RRR-alpha-tocopherol: the free phenol, acetate ester, and succinate ester forms of vitamin E
    • Cheeseman, K.H., Holley, A.E., Kelly, F.J., et al. (1995) Biokinetics in humans of RRR-alpha-tocopherol: the free phenol, acetate ester, and succinate ester forms of vitamin E. Free Radic Biol Med 19, 591-598.
    • (1995) Free Radic Biol Med , vol.19 , pp. 591-598
    • Cheeseman, K.H.1    Holley, A.E.2    Kelly, F.J.3
  • 23
    • 77958144919 scopus 로고    scopus 로고
    • Ataxia with vitamin E deficiency: update of molecular diagnosis
    • Di Donato, I., Bianchi, S., and Federico, A. (2010) Ataxia with vitamin E deficiency: update of molecular diagnosis. Neurol Sci 31, 511-515.
    • (2010) Neurol Sci , vol.31 , pp. 511-515
    • De Donato, I.1    Bianchi, S.2    Federico, A.3
  • 24
    • 0028961271 scopus 로고
    • Ataxia with vitamin E deficiency: refinement of genetic localization and analysis of linkage disequilibrium by using new markers in 14 families
    • Doerflinger, N., Linder, C., Ouahchi, K., et al. (1995) Ataxia with vitamin E deficiency: refinement of genetic localization and analysis of linkage disequilibrium by using new markers in 14 families. Am J Hum Genet 56, 1116-1124.
    • (1995) Am J Hum Genet , vol.56 , pp. 1116-1124
    • Doerflinger, N.1    Linder, C.2    Ouahchi, K.3
  • 25
    • 85179232705 scopus 로고    scopus 로고
    • Vitamin E: Food Chemistry, Composition, and Analysis
    • Marcel Dekker, New York
    • Eitenmiller, R. and Lee, J. (2004) Vitamin E: Food Chemistry, Composition, and Analysis. Marcel Dekker, New York.
    • (2004)
    • Eitenmiller, R.1    Lee, J.2
  • 26
    • 37049201550 scopus 로고
    • On the existence of a hitherto unrecognized dietary factor essential for reproduction
    • Evans, H.M. and Bishop, K.S. (1922) On the existence of a hitherto unrecognized dietary factor essential for reproduction. Science 56, 650-651.
    • (1922) Science , vol.56 , pp. 650-651
    • Evans, H.M.1    Bishop, K.S.2
  • 27
    • 84886985315 scopus 로고    scopus 로고
    • Risk assessment: vitamin E
    • Expert Group on Vitamins and Minerals, In M.J.S. Langman (ed.), Food Standards Agency, London
    • Expert Group on Vitamins and Minerals (2003) Risk assessment: vitamin E. In M.J.S. Langman (ed.), Safe Upper Levels for Vitamins and Minerals. Food Standards Agency, London. www.food.gov.uk/multimedia/pdfs/vitmin2003.pdf
    • (2003) Safe Upper Levels for Vitamins and Minerals
  • 28
    • 68249156859 scopus 로고    scopus 로고
    • Vitamin E
    • FAO, In K. Tontisirin and G. Clugston (eds), 2nd Edn. World Health Organization, Geneva
    • FAO (2004) Vitamin E. In K. Tontisirin and G. Clugston (eds), Vitamin and Mineral Requirements in Human Nutrition, 2nd Edn. World Health Organization, Geneva, pp. 94-107.
    • (2004) Vitamin and Mineral Requirements in Human Nutrition , pp. 94-107
  • 29
    • 84886966682 scopus 로고    scopus 로고
    • 14, Appendix F: Calculate the Percent Daily Value for the Appropriate Nutrients
    • Food and Drug Administration, Guidance for Industry; A Food Labeling Guide, Jan 2
    • Food and Drug Administration (2009) 14, Appendix F: Calculate the Percent Daily Value for the Appropriate Nutrients. Guidance for Industry; A Food Labeling Guide. http://www.fda.gov/Food/GuidanceComplianceRegulatoryInformation/GuidanceDocuments/FoodLabelingNutrition/FoodLabelingGuide/ucm064928.htm. Jan 2, 2011.
    • (2009)
  • 30
    • 45749159289 scopus 로고    scopus 로고
    • Sex differences in the inhibition of γ-tocopherol metabolism by a single dose of dietary sesame oil in healthy subjects
    • Frank, J., Lee, S., Leonard, S.W., et al. (2008) Sex differences in the inhibition of γ-tocopherol metabolism by a single dose of dietary sesame oil in healthy subjects Am J Clin Nutr 87, 1723-1729.
    • (2008) Am J Clin Nutr , vol.87 , pp. 1723-1729
    • Frank, J.1    Lee, S.2    Leonard, S.W.3
  • 31
    • 0034566857 scopus 로고    scopus 로고
    • Alpha-tocopherol and protein kinase C inhibition enhance platelet-derived nitric oxide release
    • Freedman, J.E., Li, L., Sauter, R., et al. (2000) Alpha-tocopherol and protein kinase C inhibition enhance platelet-derived nitric oxide release. FASEB J 14, 2377-2379.
    • (2000) FASEB J , vol.14 , pp. 2377-2379
    • Freedman, J.E.1    Li, L.2    Sauter, R.3
  • 32
    • 65349107677 scopus 로고    scopus 로고
    • Gamma-tocotrienol and gamma-tocopherol are primarily metabolized to conjugated 2-(beta-carboxyethyl)-6-hydroxy-2,7,8-trimethylchroman and sulfated long-chain carboxychromanols in rats
    • Freiser, H. and Jiang, Q. (2009a) Gamma-tocotrienol and gamma-tocopherol are primarily metabolized to conjugated 2-(beta-carboxyethyl)-6-hydroxy-2,7,8-trimethylchroman and sulfated long-chain carboxychromanols in rats. J Nutr, 139, 884-889.
    • (2009) J Nutr , vol.139 , pp. 884-889
    • Freiser, H.1    Jiang, Q.2
  • 33
    • 64249159192 scopus 로고    scopus 로고
    • Optimization of the enzymatic hydrolysis and analysis of plasma conjugated gamma-CEHC and sulfated long-chain carboxychromanols, metabolites of vitamin E
    • Freiser, H. and Jiang, Q. (2009b) Optimization of the enzymatic hydrolysis and analysis of plasma conjugated gamma-CEHC and sulfated long-chain carboxychromanols, metabolites of vitamin E. Anal Biochem 388, 260-265.
    • (2009) Anal Biochem , vol.388 , pp. 260-265
    • Freiser, H.1    Jiang, Q.2
  • 34
    • 0035726073 scopus 로고    scopus 로고
    • Effect of vitamin E supplementation in patients with ataxia with vitamin E deficiency
    • Gabsi, S., Gouider-Khouja, N., Belal, S., et al. (2001) Effect of vitamin E supplementation in patients with ataxia with vitamin E deficiency. Eur J Neurol 8, 477-481.
    • (2001) Eur J Neurol , vol.8 , pp. 477-481
    • Gabsi, S.1    Gouider-Khouja, N.2    Belal, S.3
  • 35
    • 34748854274 scopus 로고    scopus 로고
    • Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study
    • Glynn, R.J., Ridker, P.M., Goldhaber, S.Z., et al. (2007) Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study. Circulation 116, 1497-1503.
    • (2007) Circulation , vol.116 , pp. 1497-1503
    • Glynn, R.J.1    Ridker, P.M.2    Goldhaber, S.Z.3
  • 36
    • 0037047373 scopus 로고    scopus 로고
    • Effects of lipoprotein lipase on uptake and transcytosis of low density lipoprotein (LDL) and LDL-associated alpha-tocopherol in a porcine in vitro blood-brain barrier model
    • Goti, D., Balazs, Z., Panzenboeck, U., et al. (2002) Effects of lipoprotein lipase on uptake and transcytosis of low density lipoprotein (LDL) and LDL-associated alpha-tocopherol in a porcine in vitro blood-brain barrier model. J Biol Chem 277, 28537-28544.
    • (2002) J Biol Chem , vol.277 , pp. 28537-28544
    • Goti, D.1    Balazs, Z.2    Panzenboeck, U.3
  • 37
    • 46749123821 scopus 로고    scopus 로고
    • gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury
    • Hamahata, A., Enkhbaatar, P., Kraft, E.R., et al. (2008) gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury. Free Radic Biol Med 45, 425-433.
    • (2008) Free Radic Biol Med , vol.45 , pp. 425-433
    • Hamahata, A.1    Enkhbaatar, P.2    Kraft, E.R.3
  • 38
    • 17844398242 scopus 로고    scopus 로고
    • Vitamins E and C are safe across a broad range of intakes
    • Hathcock, J.N., Azzi, A., Blumberg, J., et al. (2005) Vitamins E and C are safe across a broad range of intakes. Am J Clin Nutr 81, 736-745.
    • (2005) Am J Clin Nutr , vol.81 , pp. 736-745
    • Hathcock, J.N.1    Azzi, A.2    Blumberg, J.3
  • 39
    • 42049098411 scopus 로고    scopus 로고
    • Development and physiological regulation of intestinal lipid absorption
    • III. Intestinal transporters and cholesterol absorption
    • Hui, D.Y., Labonte, E.D., and Howles, P.N. (2008) Development and physiological regulation of intestinal lipid absorption. III. Intestinal transporters and cholesterol absorption. Am J Physiol Gastrointest Liver Physiol 294, G839-843.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Hui, D.Y.1    Labonte, E.D.2    Howles, P.N.3
  • 40
    • 0003844788 scopus 로고    scopus 로고
    • Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids
    • Institute of Medicine, Food and Nutrition Board and Institute of Medicine. National Academy Press, Washington, DC
    • Institute of Medicine (2000) Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Food and Nutrition Board and Institute of Medicine. National Academy Press, Washington, DC.
    • (2000)
  • 41
    • 55049112715 scopus 로고    scopus 로고
    • Vitamin E for Alzheimer's disease and mild cognitive impairment
    • Isaac, M.G., Quinn, R., and Tabet, N. (2008) Vitamin E for Alzheimer's disease and mild cognitive impairment. Cochrane Database Syst Rev CD002854.
    • (2008) Cochrane Database Syst Rev
    • Isaac, M.G.1    Quinn, R.2    Tabet, N.3
  • 42
    • 0035489789 scopus 로고    scopus 로고
    • Bioavailability of vitamin E as function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products
    • Iuliano, L., Micheletta, F., Maranghi, M., et al. (2001) Bioavailability of vitamin E as function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products. Arterioscler Thromb Vasc Biol 21, E34-37.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21
    • Iuliano, L.1    Micheletta, F.2    Maranghi, M.3
  • 43
    • 34248183943 scopus 로고    scopus 로고
    • Identification and quantitation of novel vitamin E metabolites, sulfated long-chain carboxychromanols, in human A549 cells and in rats
    • Jiang, Q., Freiser, H., Wood, K.V., et al. (2007) Identification and quantitation of novel vitamin E metabolites, sulfated long-chain carboxychromanols, in human A549 cells and in rats. J Lipid Res 48, 1221-1230.
    • (2007) J Lipid Res , vol.48 , pp. 1221-1230
    • Jiang, Q.1    Freiser, H.2    Wood, K.V.3
  • 44
    • 0141838103 scopus 로고    scopus 로고
    • Human placental trophoblast cells express alpha-tocopherol transfer protein
    • Kaempf-Rotzoll, D.E., Horiguchi, M., Hashiguchi, K., et al. (2003) Human placental trophoblast cells express alpha-tocopherol transfer protein. Placenta 24, 439-444.
    • (2003) Placenta , vol.24 , pp. 439-444
    • Kaempf-Rotzoll, D.E.1    Horiguchi, M.2    Hashiguchi, K.3
  • 45
    • 0035992892 scopus 로고    scopus 로고
    • Alpha-tocopherol transfer protein is specifically localized at the implantation site of pregnant mouse uterus
    • Kaempf-Rotzoll, D.E., Igarashi, K., Aoki, J., et al. (2002) Alpha-tocopherol transfer protein is specifically localized at the implantation site of pregnant mouse uterus. Biol Reprod 67, 599-604.
    • (2002) Biol Reprod , vol.67 , pp. 599-604
    • Kaempf-Rotzoll, D.E.1    Igarashi, K.2    Aoki, J.3
  • 46
    • 27544458284 scopus 로고    scopus 로고
    • Delivery of orally supplemented alpha-tocotrienol to vital organs of rats and tocopherol-transport protein deficient mice
    • Khanna, S., Patel, V., Rink, C., et al. (2005) Delivery of orally supplemented alpha-tocotrienol to vital organs of rats and tocopherol-transport protein deficient mice. Free Radic Biol Med 39, 1310-1319.
    • (2005) Free Radic Biol Med , vol.39 , pp. 1310-1319
    • Khanna, S.1    Patel, V.2    Rink, C.3
  • 47
    • 6444222368 scopus 로고    scopus 로고
    • Vitamin E bioavailability from fortified breakfast cereal is greater than that from encapsulated supplements
    • Leonard, S.W., Good, C.K., Gugger, E.T., et al. (2004) Vitamin E bioavailability from fortified breakfast cereal is greater than that from encapsulated supplements. Am J Clin Nutr 79, 86-92.
    • (2004) Am J Clin Nutr , vol.79 , pp. 86-92
    • Leonard, S.W.1    Good, C.K.2    Gugger, E.T.3
  • 48
    • 27244433672 scopus 로고    scopus 로고
    • Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration
    • Leonard, S.W., Gumpricht, E., Devereaux, M.W., et al. (2005a) Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration. J Lipid Res 46, 1068-1075.
    • (2005) J Lipid Res , vol.46 , pp. 1068-1075
    • Leonard, S.W.1    Gumpricht, E.2    Devereaux, M.W.3
  • 49
    • 36048998833 scopus 로고    scopus 로고
    • Effects of vitamin E on cholesterol levels of hypercholesterolemic patients receiving statins
    • Leonard, S.W., Joss, J.D., Mustacich, D.J., et al. (2007) Effects of vitamin E on cholesterol levels of hypercholesterolemic patients receiving statins. Am J Health-System Pharm 64, 2257-2266.
    • (2007) Am J Health-System Pharm , vol.64 , pp. 2257-2266
    • Leonard, S.W.1    Joss, J.D.2    Mustacich, D.J.3
  • 50
    • 14644404970 scopus 로고    scopus 로고
    • Studies in humans using deuterium-labeled alpha-and gamma-tocopherol demonstrate faster plasma gamma-tocopherol disappearance and greater gamma-metabolite production
    • Leonard, S.W., Paterson, E., Atkinson, J.K., et al. (2005b) Studies in humans using deuterium-labeled alpha-and gamma-tocopherol demonstrate faster plasma gamma-tocopherol disappearance and greater gamma-metabolite production. Free Radic Biol Med 38, 857-866.
    • (2005) Free Radic Biol Med , vol.38 , pp. 857-866
    • Leonard, S.W.1    Paterson, E.2    Atkinson, J.K.3
  • 51
    • 77949521505 scopus 로고    scopus 로고
    • Haptoglobin: basic and clinical aspects
    • Levy, A.P., Asleh, R., Blum, S., et al. (2010) Haptoglobin: basic and clinical aspects. Antioxid Redox Signal 12, 293-304.
    • (2010) Antioxid Redox Signal , vol.12 , pp. 293-304
    • Levy, A.P.1    Asleh, R.2    Blum, S.3
  • 52
    • 79551694373 scopus 로고    scopus 로고
    • Alpha-tocopherol modulates transcriptional activities that affect essential biological processes in bovine cells
    • Li, C.J., Li, R.W., and Elsasser, T.H. (2010) Alpha-tocopherol modulates transcriptional activities that affect essential biological processes in bovine cells. Gene Regul Syst Biol 4, 109-124.
    • (2010) Gene Regul Syst Biol , vol.4 , pp. 109-124
    • Li, C.J.1    Li, R.W.2    Elsasser, T.H.3
  • 53
    • 0029945977 scopus 로고    scopus 로고
    • Gas chromatography-mass spectrometry analysis of vitamin E and its oxidation products
    • Liebler, D.C., Burr, J.A., Philips, L., et al. (1996) Gas chromatography-mass spectrometry analysis of vitamin E and its oxidation products. Anal Biochem 236, 27-34.
    • (1996) Anal Biochem , vol.236 , pp. 27-34
    • Liebler, D.C.1    Burr, J.A.2    Philips, L.3
  • 54
    • 20044383911 scopus 로고    scopus 로고
    • Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial
    • Lonn, E., Bosch, J., Yusuf, S., et al. (2005) Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial. JAMA 293, 1338-1347.
    • (2005) JAMA , vol.293 , pp. 1338-1347
    • Lonn, E.1    Bosch, J.2    Yusuf, S.3
  • 55
    • 0029866829 scopus 로고    scopus 로고
    • Lipid peroxidation in neural tissues and fractions from vitamin E-deficient rats
    • Macevilly, C.J. and Muller, D.P. (1996) Lipid peroxidation in neural tissues and fractions from vitamin E-deficient rats. Free Radic Biol Med 20, 639-648.
    • (1996) Free Radic Biol Med , vol.20 , pp. 639-648
    • Macevilly, C.J.1    Muller, D.P.2
  • 56
    • 1842579994 scopus 로고    scopus 로고
    • Intake of alpha-tocopherol is limited among US adults
    • Maras, J.E., Bermudez, O.I., Qiao, N., et al. (2004) Intake of alpha-tocopherol is limited among US adults. J Am Diet Assoc 104, 567-575.
    • (2004) J Am Diet Assoc , vol.104 , pp. 567-575
    • Maras, J.E.1    Bermudez, O.I.2    Qiao, N.3
  • 57
    • 20244372520 scopus 로고    scopus 로고
    • Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice
    • Mardones, P., Quinones, V., Amigo, L., et al. (2001) Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice. J Lipid Res 42, 170-180.
    • (2001) J Lipid Res , vol.42 , pp. 170-180
    • Mardones, P.1    Quinones, V.2    Amigo, L.3
  • 58
    • 0036193774 scopus 로고    scopus 로고
    • Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice
    • Mardones, P., Strobel, P., Miranda, S., et al. (2002) Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice. J Nutr 132, 443-449.
    • (2002) J Nutr , vol.132 , pp. 443-449
    • Mardones, P.1    Strobel, P.2    Miranda, S.3
  • 59
    • 0035478983 scopus 로고    scopus 로고
    • Oxidative stress in athletes during extreme endurance exercise
    • Mastaloudis, A., Leonard, S.W., and Traber, M.G. (2001) Oxidative stress in athletes during extreme endurance exercise. Free Radic Biol Med 31, 911-922.
    • (2001) Free Radic Biol Med , vol.31 , pp. 911-922
    • Mastaloudis, A.1    Leonard, S.W.2    Traber, M.G.3
  • 60
    • 0042594614 scopus 로고    scopus 로고
    • The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein
    • Meier, R., Tomizaki, T., Schulze-Briese, C., et al. (2003) The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein. J Mol Biol 331, 725-734.
    • (2003) J Mol Biol , vol.331 , pp. 725-734
    • Meier, R.1    Tomizaki, T.2    Schulze-Briese, C.3
  • 61
    • 4043056768 scopus 로고    scopus 로고
    • Vitamin E and respiratory tract infections in elderly nursing home residents: a randomized controlled trial
    • Meydani, S.N., Leka, L.S., Fine, B.C., et al. (2004) Vitamin E and respiratory tract infections in elderly nursing home residents: a randomized controlled trial. JAMA 292, 828-836.
    • (2004) JAMA , vol.292 , pp. 828-836
    • Meydani, S.N.1    Leka, L.S.2    Fine, B.C.3
  • 62
    • 19944427642 scopus 로고    scopus 로고
    • Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality
    • Miller, E.R., 3rd, Paston-Barriuso, R., Dalal, D., et al. (2005) Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 142, 37-46.
    • (2005) Ann Intern Med , vol.142 , pp. 37-46
    • Miller, E.R.1    Paston-Barriuso, R.2    Dalal, D.3
  • 63
    • 38549138535 scopus 로고    scopus 로고
    • Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both Type 2 diabetes mellitus and the haptoglobin 2-2 genotype
    • Milman, U., Blum, S., Shapira, C., et al. (2008) Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both Type 2 diabetes mellitus and the haptoglobin 2-2 genotype. A prospective double-blinded clinical trial. Arterioscler Thromb Vasc Biol 28, 1-7.
    • (2008) A prospective double-blinded clinical trial. Arterioscler Thromb Vasc Biol , vol.28 , pp. 1-7
    • Milman, U.1    Blum, S.2    Shapira, C.3
  • 64
    • 0345598924 scopus 로고    scopus 로고
    • Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: implications for ataxia with vitamin E deficiency
    • Min, K.C., Kovall, R.A., and Hendrickson, W.A. (2003) Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: implications for ataxia with vitamin E deficiency. Proc Natl Acad Sci USA 100, 14713-14718.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14713-14718
    • Min, K.C.1    Kovall, R.A.2    Hendrickson, W.A.3
  • 65
    • 49649098275 scopus 로고    scopus 로고
    • Mechanisms of ligand transfer by the hepatic tocopherol transfer protein
    • Morley, S., Cecchini, M., Zhang, W., et al. (2008) Mechanisms of ligand transfer by the hepatic tocopherol transfer protein. J Biol Chem 283, 17797-17804.
    • (2008) J Biol Chem , vol.283 , pp. 17797-17804
    • Morley, S.1    Cecchini, M.2    Zhang, W.3
  • 66
    • 11144354632 scopus 로고    scopus 로고
    • Localization of alpha-tocopherol transfer protein in trophoblast, fetal capillaries ' endothelium and amnion epithelium of human term placenta
    • Muller-Schmehl, K., Beninde, J., Finckh, B., et al. (2004) Localization of alpha-tocopherol transfer protein in trophoblast, fetal capillaries ' endothelium and amnion epithelium of human term placenta. Free Radic Res 38, 413-420.
    • (2004) Free Radic Res , vol.38 , pp. 413-420
    • Muller-Schmehl, K.1    Beninde, J.2    Finckh, B.3
  • 67
    • 0031824302 scopus 로고    scopus 로고
    • Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice
    • Mustacich, D.J., Shields, J., Horton, R.A., et al. (1998) Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice. Arch Biochem Biophys 350, 183-192.
    • (1998) Arch Biochem Biophys , vol.350 , pp. 183-192
    • Mustacich, D.J.1    Shields, J.2    Horton, R.A.3
  • 68
    • 74149088244 scopus 로고    scopus 로고
    • Alpha-tocopherol beta-oxidation localized to rat liver mitochondria
    • Mustacich, D.J., Leonard, S.W., Patel, N.K., et al. (2010) Alpha-tocopherol beta-oxidation localized to rat liver mitochondria. Free Radic Biol Med 48, 73-81.
    • (2010) Free Radic Biol Med , vol.48 , pp. 73-81
    • Mustacich, D.J.1    Leonard, S.W.2    Patel, N.K.3
  • 69
    • 45749155204 scopus 로고    scopus 로고
    • Niemann-Pick C1-like 1 mediates alpha-tocopherol transport
    • Narushima, K., Takada, T., Yamanashi, Y., et al. (2008) Niemann-Pick C1-like 1 mediates alpha-tocopherol transport. Mol Pharmacol 74, 42-49.
    • (2008) Mol Pharmacol , vol.74 , pp. 42-49
    • Narushima, K.1    Takada, T.2    Yamanashi, Y.3
  • 70
    • 34447099395 scopus 로고    scopus 로고
    • Synthesis of vitamin E
    • Netscher, T. (2007) Synthesis of vitamin E. Vitam Horm 76, 155-202.
    • (2007) Vitam Horm , vol.76 , pp. 155-202
    • Netscher, T.1
  • 71
    • 17744376942 scopus 로고    scopus 로고
    • Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements
    • Neuzil, J., Weber, T., Schroder, A., et al. (2001) Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements. FASEB J 15, 403-415.
    • (2001) FASEB J , vol.15 , pp. 403-415
    • Neuzil, J.1    Weber, T.2    Schroder, A.3
  • 72
    • 0034011076 scopus 로고    scopus 로고
    • Enantioselective synthesis of (2R,4 ′ R,8 ′ R)-alpha-tocopherol (vitamin E) based on enzymatic function
    • Nozawa, M., Takahashi, K., Kato, K., et al. (2000) Enantioselective synthesis of (2R,4 ′ R,8 ′ R)-alpha-tocopherol (vitamin E) based on enzymatic function. Chem Pharm Bull (Tokyo) 48, 272-277.
    • (2000) Chem Pharm Bull (Tokyo) , vol.48 , pp. 272-277
    • Nozawa, M.1    Takahashi, K.2    Kato, K.3
  • 73
    • 0035955685 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A1 mediates cellular secretion of alpha-tocopherol
    • Oram, J.F., Vaughan, A.M., and Stocker, R. (2001) ATP-binding cassette transporter A1 mediates cellular secretion of alpha-tocopherol. J Biol Chem 276, 39898-39902.
    • (2001) J Biol Chem , vol.276 , pp. 39898-39902
    • Oram, J.F.1    Vaughan, A.M.2    Stocker, R.3
  • 74
    • 0028876572 scopus 로고
    • Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein
    • Ouahchi, K., Arita, M., Kayden, H., et al. (1995) Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. Nature Genet 9, 141-145.
    • (1995) Nature Genet , vol.9 , pp. 141-145
    • Ouahchi, K.1    Arita, M.2    Kayden, H.3
  • 75
    • 0038348648 scopus 로고    scopus 로고
    • Ligand specificity in the CRAL-TRIO protein family
    • Panagabko, C., Morley, S., Hernandez, M., et al. (2003) Ligand specificity in the CRAL-TRIO protein family. Biochemistry 42, 6467-6474.
    • (2003) Biochemistry , vol.42 , pp. 6467-6474
    • Panagabko, C.1    Morley, S.2    Hernandez, M.3
  • 76
    • 33749340361 scopus 로고    scopus 로고
    • Natural vitamin E alpha-tocotrienol: retention in vital organs in response to long-term oral supplementation and withdrawal
    • Patel, V., Khanna, S., Roy, S., et al. (2006) Natural vitamin E alpha-tocotrienol: retention in vital organs in response to long-term oral supplementation and withdrawal. Free Radic Res 40, 763-771.
    • (2006) Free Radic Res , vol.40 , pp. 763-771
    • Patel, V.1    Khanna, S.2    Roy, S.3
  • 77
    • 52949091536 scopus 로고    scopus 로고
    • Immunohistochemical localization of alpha-tocopherol transfer protein and lipoperoxidation products in human first-trimester and term placenta
    • Rotzoll, D.E., Scherling, R., Etzl, R., et al. (2008) Immunohistochemical localization of alpha-tocopherol transfer protein and lipoperoxidation products in human first-trimester and term placenta. Eur J Obstet Gynecol Reprod Biol 140, 183-191.
    • (2008) Eur J Obstet Gynecol Reprod Biol , vol.140 , pp. 183-191
    • Rotzoll, D.E.1    Scherling, R.2    Etzl, R.3
  • 78
    • 77957754009 scopus 로고    scopus 로고
    • Cytoprotective effect of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: tocopherols and tocotrienols exert similar effects by antioxidant function
    • Saito, Y., Nishio, K., Akazawa, Y.O., et al. (2010) Cytoprotective effect of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: tocopherols and tocotrienols exert similar effects by antioxidant function. Free Radic Biol Med 49, 1542-1549.
    • (2010) Free Radic Biol Med , vol.49 , pp. 1542-1549
    • Saito, Y.1    Nishio, K.2    Akazawa, Y.O.3
  • 79
    • 0030967165 scopus 로고    scopus 로고
    • A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease
    • Sano, M., Ernesto, C., Thomas, R.G., et al. (1997) A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. N Engl J Med 336, 1216-1222.
    • (1997) The Alzheimer's Disease Cooperative Study. N Engl J Med , vol.336 , pp. 1216-1222
    • Sano, M.1    Ernesto, C.2    Thomas, R.G.3
  • 80
    • 85166538873 scopus 로고
    • Vitamin E deficiency and neurological disorders
    • In L. Packer and J. Fuchs (eds), Marcel Dekker, New York
    • Sokol, R.J. (1993) Vitamin E deficiency and neurological disorders. In L. Packer and J. Fuchs (eds), Vitamin E in Health and Disease. Marcel Dekker, New York, pp. 815-849.
    • (1993) Vitamin E in Health and Disease , pp. 815-849
    • Sokol, R.J.1
  • 81
    • 45449123054 scopus 로고
    • Isolated vitamin E deficiency in the absence of fat malabsorption-familial and sporadic cases: characterization and investigation of causes
    • Sokol, R.J., Kayden, H.J., Bettis, D.B., et al. (1988) Isolated vitamin E deficiency in the absence of fat malabsorption-familial and sporadic cases: characterization and investigation of causes. J Lab Clin Med 111, 548-559.
    • (1988) J Lab Clin Med , vol.111 , pp. 548-559
    • Sokol, R.J.1    Kayden, H.J.2    Bettis, D.B.3
  • 82
    • 0037067711 scopus 로고    scopus 로고
    • Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism: Novel mechanism of regulation of vitamin E status
    • Sontag, T.J. and Parker, R.S. (2002) Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism: Novel mechanism of regulation of vitamin E status. J Biol Chem 277, 25290-25296.
    • (2002) J Biol Chem , vol.277 , pp. 25290-25296
    • Sontag, T.J.1    Parker, R.S.2
  • 83
    • 34248198290 scopus 로고    scopus 로고
    • Influence of major structural features of tocopherols and tocotrienols on their omega-oxidation by tocopherol-omega-hydroxylase
    • Sontag, T.J. and Parker, R.S. (2007) Influence of major structural features of tocopherols and tocotrienols on their omega-oxidation by tocopherol-omega-hydroxylase. J Lipid Res 48, 1090-1098.
    • (2007) J Lipid Res , vol.48 , pp. 1090-1098
    • Sontag, T.J.1    Parker, R.S.2
  • 84
    • 0019256753 scopus 로고
    • Vitamin E changes the membrane fluidity of human platelets
    • Steiner, M. (1981) Vitamin E changes the membrane fluidity of human platelets. Biochim Biophys Acta 640, 100-105.
    • (1981) Biochim Biophys Acta , vol.640 , pp. 100-105
    • Steiner, M.1
  • 86
    • 0034610293 scopus 로고    scopus 로고
    • Increased atherosclerosis in hyperlipidemic mice deficient in alpha-tocopherol transfer protein and vitamin E
    • Terasawa, Y., Ladha, Z., Leonard, S.W., et al. (2000) Increased atherosclerosis in hyperlipidemic mice deficient in alpha-tocopherol transfer protein and vitamin E. Proc Natl Acad Sci USA 97, 13830-13834.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13830-13834
    • Terasawa, Y.1    Ladha, Z.2    Leonard, S.W.3
  • 87
    • 0034659172 scopus 로고    scopus 로고
    • Molecular action of vitamin E in lipoprotein oxidation: implications for atherosclerosis
    • Thomas, S.R. and Stocker, R. (2000) Molecular action of vitamin E in lipoprotein oxidation: implications for atherosclerosis. Free Radic Biol Med 28, 1795-1805.
    • (2000) Free Radic Biol Med , vol.28 , pp. 1795-1805
    • Thomas, S.R.1    Stocker, R.2
  • 88
    • 78650903052 scopus 로고    scopus 로고
    • Alpha-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways
    • Tiwary, R., Yu, W., Sanders, B.G., et al. (2010) Alpha-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways. Br J Cancer 104, 101-109.
    • (2010) Br J Cancer , vol.104 , pp. 101-109
    • Tiwary, R.1    Yu, W.2    Sanders, B.G.3
  • 89
    • 0001580323 scopus 로고    scopus 로고
    • Vitamin E
    • In M.E. Shils, J.A. Olson, M. Shike et al. (eds), Williams and Wilkins, Baltimore
    • Traber, M.G. (1999) Vitamin E. In M.E. Shils, J.A. Olson, M. Shike et al. (eds), Modern Nutrition in Health and Disease. Williams and Wilkins, Baltimore, pp. 347-362.
    • (1999) Modern Nutrition in Health and Disease , pp. 347-362
    • Traber, M.G.1
  • 90
    • 1042290478 scopus 로고    scopus 로고
    • Vitamin E, nuclear receptors and xenobiotic metabolism
    • Traber, M.G. (2004) Vitamin E, nuclear receptors and xenobiotic metabolism. Arch Biochem Biophys 423, 6-11.
    • (2004) Arch Biochem Biophys , vol.423 , pp. 6-11
    • Traber, M.G.1
  • 91
    • 77952373180 scopus 로고    scopus 로고
    • Regulation of xenobiotic metabolism, the only signaling function of alpha-tocopherol?
    • Traber, M.G. (2010) Regulation of xenobiotic metabolism, the only signaling function of alpha-tocopherol? Mol Nutr Food Res 54, 661-668.
    • (2010) Mol Nutr Food Res , vol.54 , pp. 661-668
    • Traber, M.G.1
  • 92
    • 34249868200 scopus 로고    scopus 로고
    • Vitamin E, antioxidant and nothing more
    • Traber, M.G. and Atkinson, J. (2007) Vitamin E, antioxidant and nothing more. Free Radic Biol Med, 43, 4-15.
    • (2007) Free Radic Biol Med , vol.43 , pp. 4-15
    • Traber, M.G.1    Atkinson, J.2
  • 93
    • 0028077110 scopus 로고
    • Human plasma vitamin E kinetics demonstrate rapid recycling of plasma RRR-α-tocopherol
    • Traber, M.G., Ramakrishnan, R., and Kayden, H.J. (1994) Human plasma vitamin E kinetics demonstrate rapid recycling of plasma RRR-α-tocopherol. Proc Natl Acad Sci USA 91, 10005-10008.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10005-10008
    • Traber, M.G.1    Ramakrishnan, R.2    Kayden, H.J.3
  • 94
    • 0025362281 scopus 로고
    • Nascent VLDL from liver perfusions of cynomolgus monkeys are preferentially enriched in RRR- compared with SRR-α tocopherol: studies using deuterated tocopherols
    • Traber, M.G., Rudel, L.L., Burton, G.W., et al. (1990a) Nascent VLDL from liver perfusions of cynomolgus monkeys are preferentially enriched in RRR- compared with SRR-α tocopherol: studies using deuterated tocopherols. J Lipid Res 31, 687-694.
    • (1990) J Lipid Res , vol.31 , pp. 687-694
    • Traber, M.G.1    Rudel, L.L.2    Burton, G.W.3
  • 95
    • 0025138431 scopus 로고
    • Impaired ability of patients with familial isolated vitamin E deficiency to incorporate alpha-tocopherol into lipoproteins secreted by the liver
    • Traber, M.G., Sokol, R.J., Burton, G.W., et al. (1990b) Impaired ability of patients with familial isolated vitamin E deficiency to incorporate alpha-tocopherol into lipoproteins secreted by the liver. J Clin Invest 85, 397-407.
    • (1990) J Clin Invest , vol.85 , pp. 397-407
    • Traber, M.G.1    Sokol, R.J.2    Burton, G.W.3
  • 96
    • 0027464942 scopus 로고
    • Impaired discrimination between stereoisomers of α-tocopherol in patients with familial isolated vitamin E deficiency
    • Traber, M.G., Sokol, R.J., Kohlschütter, A., et al. (1993) Impaired discrimination between stereoisomers of α-tocopherol in patients with familial isolated vitamin E deficiency. J Lipid Res 34, 201-210.
    • (1993) J Lipid Res , vol.34 , pp. 201-210
    • Traber, M.G.1    Sokol, R.J.2    Kohlschütter, A.3
  • 97
    • 0023265501 scopus 로고
    • Lack of tocopherol in peripheral nerves of vitamin E-deficient patients with peripheral neuropathy
    • Traber, M.G., Sokol, R.J., Ringel, S.P., et al. (1987) Lack of tocopherol in peripheral nerves of vitamin E-deficient patients with peripheral neuropathy. N Engl J Med 317, 262-265.
    • (1987) N Engl J Med , vol.317 , pp. 262-265
    • Traber, M.G.1    Sokol, R.J.2    Ringel, S.P.3
  • 98
    • 78649951793 scopus 로고    scopus 로고
    • Alpha-tocopheryl succinate induces apoptosis in erbB2-expressing breast cancer cell via NF-kappaB pathway
    • Wang, X.F., Xie, Y., Wang, H.G., et al. (2010) Alpha-tocopheryl succinate induces apoptosis in erbB2-expressing breast cancer cell via NF-kappaB pathway. Acta Pharmacol Sin 31, 1604-1610.
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 1604-1610
    • Wang, X.F.1    Xie, Y.2    Wang, H.G.3
  • 99
    • 0037145833 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial
    • Waters, D.D., Alderman, E.L., Hsia, J., et al. (2002) Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial. JAMA 288, 2432-2440.
    • (2002) JAMA , vol.288 , pp. 2432-2440
    • Waters, D.D.1    Alderman, E.L.2    Hsia, J.3
  • 100
    • 34248631076 scopus 로고    scopus 로고
    • A new compound-specific pleiotropic effect of statins: modification of plasma gamma-tocopherol levels
    • Werba, J.P., Cavalca, V., Veglia, F., et al. (2007) A new compound-specific pleiotropic effect of statins: modification of plasma gamma-tocopherol levels. Atherosclerosis 193, 229-233.
    • (2007) Atherosclerosis , vol.193 , pp. 229-233
    • Werba, J.P.1    Cavalca, V.2    Veglia, F.3
  • 101
    • 77951824199 scopus 로고    scopus 로고
    • Synthesis and characterization of BODIPY-alpha-tocopherol: a fluorescent form of vitamin E
    • West, R., Panagabko, C., and Atkinson, J. (2010) Synthesis and characterization of BODIPY-alpha-tocopherol: a fluorescent form of vitamin E. J Org Chem 75, 2883-2892.
    • (2010) J Org Chem , vol.75 , pp. 2883-2892
    • West, R.1    Panagabko, C.2    Atkinson, J.3
  • 102
    • 45049087219 scopus 로고    scopus 로고
    • In vivo gamma-tocopherol supplementation decreases systemic oxidative stress and cytokine responses of human monocytes in normal and asthmatic subjects
    • Wiser, J., Alexis, N.E., Jiang, Q., et al. (2008) In vivo gamma-tocopherol supplementation decreases systemic oxidative stress and cytokine responses of human monocytes in normal and asthmatic subjects. Free Radic Biol Med 45, 40-49.
    • (2008) Free Radic Biol Med , vol.45 , pp. 40-49
    • Wiser, J.1    Alexis, N.E.2    Jiang, Q.3
  • 103
    • 0034526981 scopus 로고    scopus 로고
    • Regulation by vitamin E of the scavenger receptor BI in rat liver and HepG2 cells
    • Witt, W., Kolleck, I., Fechner, H., et al. (2000) Regulation by vitamin E of the scavenger receptor BI in rat liver and HepG2 cells. J Lipid Res 41, 2009-2016.
    • (2000) J Lipid Res , vol.41 , pp. 2009-2016
    • Witt, W.1    Kolleck, I.2    Fechner, H.3
  • 104
    • 33750900766 scopus 로고    scopus 로고
    • Higher baseline serum concentrations of vitamin E are associated with lower total and cause-specific mortality in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study
    • Wright, M.E., Lawson, K.A., Weinstein, S.J., et al. (2006) Higher baseline serum concentrations of vitamin E are associated with lower total and cause-specific mortality in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. Am J Clin Nutr 84, 1200-1207.
    • (2006) Am J Clin Nutr , vol.84 , pp. 1200-1207
    • Wright, M.E.1    Lawson, K.A.2    Weinstein, S.J.3
  • 105
    • 73249135637 scopus 로고    scopus 로고
    • In vitro stable isotope labeling for discovery of novel metabolites by liquid chromatography-mass spectrometry: confirmation of gamma-tocopherol metabolism in human A549 cell
    • Yang, W.C., Regnier, F.E., Jiang, Q., et al. (2010) In vitro stable isotope labeling for discovery of novel metabolites by liquid chromatography-mass spectrometry: confirmation of gamma-tocopherol metabolism in human A549 cell. J Chromatogr A, 1217, 667-675.
    • (2010) J Chromatogr A , vol.1217 , pp. 667-675
    • Yang, W.C.1    Regnier, F.E.2    Jiang, Q.3
  • 106
    • 0034059016 scopus 로고    scopus 로고
    • Postmortem study of ataxia with retinitis pigmentosa by mutation of the alpha-tocopherol transfer protein gene
    • Yokota, T., Uchihara, T., Kumagai, J., et al. (2000) Postmortem study of ataxia with retinitis pigmentosa by mutation of the alpha-tocopherol transfer protein gene. J Neurol Neurosurg Psychiatry 68, 521-525.
    • (2000) J Neurol Neurosurg Psychiatry , vol.68 , pp. 521-525
    • Yokota, T.1    Uchihara, T.2    Kumagai, J.3
  • 107
    • 0035910076 scopus 로고    scopus 로고
    • Delayed-onset ataxia in mice lacking alpha-tocopherol transfer protein: model for neuronal degeneration caused by chronic oxidative stress
    • Yokota, T., Igarashi, K., Uchihara, T., et al. (2001) Delayed-onset ataxia in mice lacking alpha-tocopherol transfer protein: model for neuronal degeneration caused by chronic oxidative stress. Proc Natl Acad Sci USA 98, 15185-15190.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 15185-15190
    • Yokota, T.1    Igarashi, K.2    Uchihara, T.3
  • 108
    • 0038520017 scopus 로고    scopus 로고
    • RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria
    • Yu, W., Sanders, B.G., and Kline, K. (2003) RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria. Cancer Res 63, 2483-2491.
    • (2003) Cancer Res , vol.63 , pp. 2483-2491
    • Yu, W.1    Sanders, B.G.2    Kline, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.