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Volumn 31, Issue 12, 2010, Pages 1604-1610

α-Tocopheryl succinate induces apoptosis in erbB2-expressing breast cancer cell via NF-κB pathway

Author keywords

TOS; apoptosis; breast cancer; erbB2; hrTRAIL; NF B

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; CASPASE; CASPASE 3; CASPASE 8; CELL PROTEIN; CELLULAR INHIBITOR OF APOPTOSIS PROTEIN 1; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLICE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOCORTIN 5; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; UNCLASSIFIED DRUG;

EID: 78649951793     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.171     Document Type: Article
Times cited : (14)

References (29)
  • 1
    • 2442701289 scopus 로고    scopus 로고
    • The ErbB/HER receptor protein-tyrosine kinases and cancer
    • Roskoski R. The ErbB/HER receptor protein-tyrosine kinases and cancer. Biochem Biophys Res Commun 2004;319:1-11.
    • (2004) Biochem. Biophys. Res. Commun. , vol.319 , pp. 1-11
    • Roskoski, R.1
  • 2
    • 33750615735 scopus 로고    scopus 로고
    • Simultaneous amplifcation of Her (ErbB2) and topoisomerase IIα (TOP2A) genes in combination therapy in cancer
    • Jarvinen TA, Liu ET. Simultaneous amplifcation of Her (ErbB2) and topoisomerase IIα (TOP2A) genes in combination therapy in cancer. Curr cancer drug targets 2006;6:579-602.
    • (2006) Curr. Cancer Drug Targets , vol.6 , pp. 579-602
    • Jarvinen, T.A.1    Liu, E.T.2
  • 3
    • 0041802784 scopus 로고    scopus 로고
    • Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents
    • DOI 10.1016/S1471-4892(03)00078-X, PII S147148920300078X
    • Ward SG, Finan P. Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents. Curr Opin Pharmacol 2003;3:426-34. (Pubitemid 36908947)
    • (2003) Current Opinion in Pharmacology , vol.3 , Issue.4 , pp. 426-434
    • Ward, S.G.1    Finan, P.2
  • 4
    • 0037352170 scopus 로고    scopus 로고
    • Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
    • Chang F, Lee JT, Navolanic PM, Steelman LS, Shelton JG, Blalock WL, et al. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia 2003;17:590-603.
    • (2003) Leukemia , vol.17 , pp. 590-603
    • Chang, F.1    Lee, J.T.2    Navolanic, P.M.3    Steelman, L.S.4    Shelton, J.G.5    Blalock, W.L.6
  • 6
    • 22144449607 scopus 로고    scopus 로고
    • Constitutive activation of PI3K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model
    • Shukla S, Maclennan GT, Marengo SR, Resnick MI, Gupta S. Constitutive activation of PI3K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model. Prostate 2005;64:224-39.
    • (2005) Prostate , vol.64 , pp. 224-239
    • Shukla, S.1    Maclennan, G.T.2    Marengo, S.R.3    Resnick, M.I.4    Gupta, S.5
  • 7
    • 0032410818 scopus 로고    scopus 로고
    • The inhibitors of apoptosis protein (IAPs) and their emerging role in cancer
    • La Casse EC, Baird S, Korneluk RG, MacKenzie AE. The inhibitors of apoptosis protein (IAPs) and their emerging role in cancer. Oncogene 1998;17:3247-59.
    • (1998) Oncogene , vol.17 , pp. 3247-3259
    • La Casse, E.C.1    Baird, S.2    Korneluk, R.G.3    MacKenzie, A.E.4
  • 8
    • 13244287736 scopus 로고    scopus 로고
    • Amiloride augments TRAIL-induced apoptotic death by inhibiting phosphorylation of kinases and phosphatases associated with the P13KAkt pathway
    • Kim KM, Lee YJ. Amiloride augments TRAIL-induced apoptotic death by inhibiting phosphorylation of kinases and phosphatases associated with the P13KAkt pathway. Oncogene 2005;24:355-66.
    • (2005) Oncogene , vol.24 , pp. 355-366
    • Kim, K.M.1    Lee, Y.J.2
  • 10
    • 9944254161 scopus 로고    scopus 로고
    • Vitamin E analogs trigger apoptosis in HER2/erbB2-overexpressing breast cancer cells by signaling via the mitochondrial pathway
    • Wang XF, Witting PK, Salvatore BA, Neuzil J. Vitamin E analogs trigger apoptosis in HER2/erbB2-overexpressing breast cancer cells by signaling via the mitochondrial pathway. Biochem Biophys Res Commun 2005;326:282-9.
    • (2005) Biochem. Biophys. Res. Commun. , vol.326 , pp. 282-289
    • Wang, X.F.1    Witting, P.K.2    Salvatore, B.A.3    Neuzil, J.4
  • 11
    • 0033572413 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand's anti-tumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11
    • Gliniak B, Le T. Tumor necrosis factor-related apoptosis-inducing ligand's anti-tumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11. Cancer Res 1999;59:6153-8.
    • (1999) Cancer Res. , vol.59 , pp. 6153-6158
    • Gliniak, B.1    Le, T.2
  • 12
    • 0035120415 scopus 로고    scopus 로고
    • Combination of tumour necrosis factor-related apoptosisinducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells
    • Matsuzaki H, Schmied BM, Ulrich A, Standop J, Scheider MB, Batra SK, et al. Combination of tumour necrosis factor-related apoptosisinducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells. Clin Cancer Res 2001;7:407-14.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 407-414
    • Matsuzaki, H.1    Schmied, B.M.2    Ulrich, A.3    Standop, J.4    Scheider, M.B.5    Batra, S.K.6
  • 13
    • 0035920230 scopus 로고    scopus 로고
    • Rel/NF-κB transcription factors protect against tumour necrosis factor (TNF) - Related apoptosis-inducing ligand (TRAIL)-induced apoptosis by upregulating the TRAIL decoy receptor DcR1
    • Bernard D, Quatannens B, Vandenbunder B, Abbadie C. Rel/NF-κB transcription factors protect against tumour necrosis factor (TNF) - related apoptosis-inducing ligand (TRAIL)-induced apoptosis by upregulating the TRAIL decoy receptor DcR1. J Biol Chem 2001;276:27322-8.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27322-27328
    • Bernard, D.1    Quatannens, B.2    Vandenbunder, B.3    Abbadie, C.4
  • 14
    • 2442455374 scopus 로고    scopus 로고
    • α-Tocopheryl succinate and TRAIL selectively synergise in induction of apoptosis in human alignant mesothelioma cells
    • Tomasetti M, Rippo MR, Alleva R, Moretti S, Andera L, Neuzil J, et al. α-Tocopheryl succinate and TRAIL selectively synergise in induction of apoptosis in human alignant mesothelioma cells. Br J Cancer 2004;90:1644-53.
    • (2004) Br. J. Cancer , vol.90 , pp. 1644-1653
    • Tomasetti, M.1    Rippo, M.R.2    Alleva, R.3    Moretti, S.4    Andera, L.5    Neuzil, J.6
  • 15
    • 34248200033 scopus 로고    scopus 로고
    • A peptide conjugate of vitamin E succinate targets breast cancer cells with high erbB2 expression
    • Wang XF, Birringer M, Dong LF, Veprek P, Low P, Swettenham E, et al. A peptide conjugate of vitamin E succinate targets breast cancer cells with high erbB2 expression. Cancer Res 2007;67:3337-44.
    • (2007) Cancer Res. , vol.67 , pp. 3337-3344
    • Wang, X.F.1    Birringer, M.2    Dong, L.F.3    Veprek, P.4    Low, P.5    Swettenham, E.6
  • 16
    • 0037434422 scopus 로고    scopus 로고
    • α-Tocopheryl succinate sensitises T lymphoma cells to TRAIL killing by suppressing NF-κB activation
    • Dalen H, Neuzil J. α-Tocopheryl succinate sensitises T lymphoma cells to TRAIL killing by suppressing NF-κB activation. Br J Cancer 2003;88:153-8.
    • (2003) Br. J. Cancer , vol.88 , pp. 153-158
    • Dalen, H.1    Neuzil, J.2
  • 17
    • 0345103741 scopus 로고    scopus 로고
    • Mitochondria play a central role in apoptosis induced by α-tocopheryl succinate, an agent with anticancer activity: Comparison with receptormediated pro-apoptotic signaling
    • Weber T, Dalen H, Andera L, Nègre-Salvayre A, Augé N, Sticha M, et al. Mitochondria play a central role in apoptosis induced by α-tocopheryl succinate, an agent with anticancer activity: comparison with receptormediated pro-apoptotic signaling. Biochemistry 2003;42:4277-91.
    • (2003) Biochemistry , vol.42 , pp. 4277-4291
    • Weber, T.1    Dalen, H.2    Andera, L.3    Nègre-Salvayre, A.4    Augé, N.5    Sticha, M.6
  • 18
    • 0036803293 scopus 로고    scopus 로고
    • The IAP proteins
    • Holcik M. The IAP proteins. Trends Genet 2002;18:537-8.
    • (2002) Trends Genet. , vol.18 , pp. 537-538
    • Holcik, M.1
  • 19
    • 18744425429 scopus 로고    scopus 로고
    • The caspase-8 inhibitor FLIP promotes activation of NF kappaB and Erk signaling pathway
    • Kataoka T, Budd RC, Holler N, Thome M, Martinon F, Irmler M, et al. The caspase-8 inhibitor FLIP promotes activation of NF kappaB and Erk signaling pathway. Curr Biol 2000;10:640-8.
    • (2000) Curr. Biol. , vol.10 , pp. 640-648
    • Kataoka, T.1    Budd, R.C.2    Holler, N.3    Thome, M.4    Martinon, F.5    Irmler, M.6
  • 21
    • 46349107548 scopus 로고    scopus 로고
    • Erbin-regulated sensitivity of MCF-7 breast cancer cells to TRAIL via ErbB2/AKT/NF-kappaB pathway
    • Liu N, Zhang J, Zhang J, Liu S, Liu Y, Zheng D. Erbin-regulated sensitivity of MCF-7 breast cancer cells to TRAIL via ErbB2/AKT/NF-kappaB pathway. J Biochem 2008;143:793-801.
    • (2008) J. Biochem. , vol.143 , pp. 793-801
    • Liu, N.1    Zhang, J.2    Zhang, J.3    Liu, S.4    Liu, Y.5    Zheng, D.6
  • 22
    • 0036672268 scopus 로고    scopus 로고
    • Induction of apoptosis in a human breast cancer cell overexpressing ErbB-2 receptor by α-tocopheryloxybutyric acid
    • Akazawa A, Nishikawa K, Suzuki K, Asano R, Kumadaki I, Satoh H, et al. Induction of apoptosis in a human breast cancer cell overexpressing ErbB-2 receptor by α-tocopheryloxybutyric acid. Jpn J Pharmacol 2002;89:417-21.
    • (2002) Jpn. J. Pharmacol. , vol.89 , pp. 417-421
    • Akazawa, A.1    Nishikawa, K.2    Suzuki, K.3    Asano, R.4    Kumadaki, I.5    Satoh, H.6
  • 23
    • 0030770774 scopus 로고    scopus 로고
    • α-Tocopheryl succinate inhibits monocytic cell adhesion to endothelial cells by suppressing NF-κB mobilization
    • Erl W, Weber C, Wardemann C, Weber PC. α-Tocopheryl succinate inhibits monocytic cell adhesion to endothelial cells by suppressing NF-κB mobilization. Am J Physiol 1997;273: H634-40.
    • (1997) Am. J. Physiol. , vol.273
    • Erl, W.1    Weber, C.2    Wardemann, C.3    Weber, P.C.4
  • 24
    • 0033210894 scopus 로고    scopus 로고
    • Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: The trail to nontoxic cancer therapeutics
    • Bonavida B, Ng CP, Jazirehi A, Schiller G, Mizutani Y. Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to nontoxic cancer therapeutics. Int J Oncol 1999;15:793-802.
    • (1999) Int. J. Oncol. , vol.15 , pp. 793-802
    • Bonavida, B.1    Ng, C.P.2    Jazirehi, A.3    Schiller, G.4    Mizutani, Y.5
  • 25
    • 0032962163 scopus 로고    scopus 로고
    • The TRAIL to selective tumor death
    • French LE, Tschopp J. The TRAIL to selective tumor death. Nat Med 1999;5:146-7.
    • (1999) Nat. Med. , vol.5 , pp. 146-147
    • French, L.E.1    Tschopp, J.2
  • 26
    • 0033596980 scopus 로고    scopus 로고
    • An APAF-1·cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
    • Zou H, Li Y, Liu X, Wang X. An APAF-1·cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem 1999;274:11549-56.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11549-11556
    • Zou, H.1    Li, Y.2    Liu, X.3    Wang, X.4
  • 27
    • 33845221022 scopus 로고    scopus 로고
    • TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma
    • Trauzold A, Schniewind B, Egberts J. TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma. Oncogene 2006;25:7434-9.
    • (2006) Oncogene , vol.25 , pp. 7434-7439
    • Trauzold, A.1    Schniewind, B.2    Egberts, J.3
  • 28
    • 0036301439 scopus 로고    scopus 로고
    • Vitamin e succinate is a potent novel antineoplastic agent with high tumor selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL, Apo2L) in vivo
    • Weber T, Lu M, Andera L, Lahm H, Gellert N, Fariss MW, et al. Vitamin e succinate is a potent novel antineoplastic agent with high tumor selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL, Apo2L) in vivo. Clin Cancer Res 2002;8:863-9.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 863-869
    • Weber, T.1    Lu, M.2    Andera, L.3    Lahm, H.4    Gellert, N.5    Fariss, M.W.6
  • 29
    • 33748423217 scopus 로고    scopus 로고
    • Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate
    • Wang XF, Dong LF, Zhao Y, Tomasetti M, Wu K, Neuzil J. Vitamin E analogues as anti-cancer agents: lessons from studies with α-tocopheryl succinate. Mol Nutr Food Res 2006;50:675-85.
    • (2006) Mol. Nutr. Food Res. , vol.50 , pp. 675-685
    • Wang, X.F.1    Dong, L.F.2    Zhao, Y.3    Tomasetti, M.4    Wu, K.5    Neuzil, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.