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Volumn 10, Issue 1, 2013, Pages

Mitochondrial-associated metabolic disorders: Foundations, pathologies and recent progress

Author keywords

Disease; Metabolism; Mitochondria; mtDNA

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; COENZYME Q REDUCTASE 2; COENZYME Q REDUCTASE 9; DNA DIRECTED DNA POLYMERASE GAMMA; ELECTRON TRANSFERRING FLAVOPROTEIN DEHYDROGENASE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MITOCHONDRIAL DNA; OXIDOREDUCTASE; POLYMERASE GAMMA; POLYMERASE GAMMA 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RNA 12S; RNA 16S; THYMIDINE PHOSPHORYLASE; TRANSFER RNA; UBIDECARENONE; UNCLASSIFIED DRUG;

EID: 84885342784     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-10-63     Document Type: Review
Times cited : (43)

References (115)
  • 1
    • 0842330598 scopus 로고    scopus 로고
    • Acyl-CoA dehydrogenases. A mechanistic overview
    • 10.1046/j.1432-1033.2003.03946.x 14728676
    • Acyl-CoA dehydrogenases. A mechanistic overview. Ghisla S, Thorpe C, Eur J Biochem 2004 271 494 508 10.1046/j.1432-1033.2003.03946.x 14728676
    • (2004) Eur J Biochem , vol.271 , pp. 494-508
    • Ghisla, S.1    Thorpe, C.2
  • 3
    • 0023644782 scopus 로고
    • Upper and lower limits of the charge translocation stoichiometry of mitochondrial electron transport
    • 3571252
    • Upper and lower limits of the charge translocation stoichiometry of mitochondrial electron transport. Beavis AD, J Biol Chem 1987 262 6165 6173 3571252
    • (1987) J Biol Chem , vol.262 , pp. 6165-6173
    • Beavis, A.D.1
  • 4
    • 47049093425 scopus 로고    scopus 로고
    • The rotary mechanism of the ATP synthase
    • 10.1016/j.abb.2008.05.004 18515057
    • The rotary mechanism of the ATP synthase. Nakamoto RK, Baylis Scanlon JA, Al-Shawi MK, Arch Biochem Biophys 2008 476 43 50 10.1016/j.abb.2008.05.004 18515057
    • (2008) Arch Biochem Biophys , vol.476 , pp. 43-50
    • Nakamoto, R.K.1    Baylis Scanlon, J.A.2    Al-Shawi, M.K.3
  • 5
    • 78049288139 scopus 로고    scopus 로고
    • Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria
    • 10.1073/pnas.1011099107 20847295
    • Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria. Watt IN, Montgomery MG, Runswick MJ, Leslie AGW, Walker JE, Proc Natl Acad Sci USA 2010 107 16823 16827 10.1073/pnas.1011099107 20847295
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 16823-16827
    • Watt, I.N.1    Montgomery, M.G.2    Runswick, M.J.3    Leslie, A.G.W.4    Walker, J.E.5
  • 6
    • 0034717940 scopus 로고    scopus 로고
    • Fatty acid import into mitochondria
    • 10.1016/S1388-1981(00)00044-5 10856709
    • Fatty acid import into mitochondria. Kerner J, Hoppel C, Biochim Biophys Acta 2000 1486 1 17 10.1016/S1388-1981(00)00044-5 10856709
    • (2000) Biochim Biophys Acta , vol.1486 , pp. 1-17
    • Kerner, J.1    Hoppel, C.2
  • 7
    • 77957602067 scopus 로고    scopus 로고
    • The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results
    • 10.1007/s10545-010-9104-8 20490924
    • The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results. Wanders RJA, Ruiter JPN, IJLst L, Waterham HR, Houten SM, J Inherit Metab Dis 2010 33 479 494 10.1007/s10545-010-9104-8 20490924
    • (2010) J Inherit Metab Dis , vol.33 , pp. 479-494
    • Wanders, R.J.A.1    Ruiter, J.P.N.2    Ijlst, L.3    Waterham, H.R.4    Houten, S.M.5
  • 8
    • 78649413837 scopus 로고    scopus 로고
    • Mitochondrial fusion and fission in cell life and death
    • 10.1038/nrm3013 21102612
    • Mitochondrial fusion and fission in cell life and death. Westermann B, Nat Rev Mol Cell Biol 2010 11 872 884 10.1038/nrm3013 21102612
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 872-884
    • Westermann, B.1
  • 9
    • 84869030015 scopus 로고    scopus 로고
    • Fusion and fission: Interlinked processes critical for mitochondrial health
    • 10.1146/annurev-genet-110410-132529 22934639
    • Fusion and fission: interlinked processes critical for mitochondrial health. Chan DC, Annu Rev Genet 2012 46 265 287 10.1146/annurev-genet-110410- 132529 22934639
    • (2012) Annu Rev Genet , vol.46 , pp. 265-287
    • Chan, D.C.1
  • 10
    • 77955298543 scopus 로고    scopus 로고
    • Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1
    • 10.1111/j.1749-6632.2010.05629.x 20649536
    • Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1. Chang C-R, Blackstone C, Ann N Y Acad Sci 2010 1201 34 39 10.1111/j.1749-6632.2010.05629.x 20649536
    • (2010) Ann N y Acad Sci , vol.1201 , pp. 34-39
    • Chang, C.-R.1    Blackstone, C.2
  • 11
    • 0043092647 scopus 로고    scopus 로고
    • The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
    • 10.1128/MCB.23.15.5409-5420.2003 12861026
    • The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1. Yoon Y, Krueger EW, Oswald BJ, McNiven MA, Mol Cell Biol 2003 23 5409 5420 10.1128/MCB.23.15.5409-5420.2003 12861026
    • (2003) Mol Cell Biol , vol.23 , pp. 5409-5420
    • Yoon, Y.1    Krueger, E.W.2    Oswald, B.J.3    McNiven, M.A.4
  • 12
    • 78650167618 scopus 로고    scopus 로고
    • Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
    • 10.1083/jcb.201007152 21149567
    • Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. Otera H, Wang C, Cleland MM, Setoguchi K, Yokota S, Youle RJ, Mihara K, J Cell Biol 2010 191 1141 1158 10.1083/jcb.201007152 21149567
    • (2010) J Cell Biol , vol.191 , pp. 1141-1158
    • Otera, H.1    Wang, C.2    Cleland, M.M.3    Setoguchi, K.4    Yokota, S.5    Youle, R.J.6    Mihara, K.7
  • 15
    • 84865544952 scopus 로고    scopus 로고
    • Mitochondrial fission, fusion, and stress
    • 10.1126/science.1219855 22936770
    • Mitochondrial fission, fusion, and stress. Youle RJ, van der Bliek AM, Science 2012 337 1062 1065 10.1126/science.1219855 22936770
    • (2012) Science , vol.337 , pp. 1062-1065
    • Youle, R.J.1    Van Der Bliek, A.M.2
  • 16
    • 78650467974 scopus 로고    scopus 로고
    • Mechanisms of mitophagy
    • 10.1038/nrm3028 21179058
    • Mechanisms of mitophagy. Youle RJ, Narendra DP, Nat Rev Mol Cell Biol 2011 12 9 14 10.1038/nrm3028 21179058
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 9-14
    • Youle, R.J.1    Narendra, D.P.2
  • 17
    • 84883605293 scopus 로고    scopus 로고
    • Insights on altered mitochondrial function and dynamics in the pathogenesis of neurodegeneration
    • 10.1186/2047-9158-2-12 23711354
    • Insights on altered mitochondrial function and dynamics in the pathogenesis of neurodegeneration. McInnes J, Transl Neurodegener 2013 2 12 10.1186/2047-9158-2-12 23711354
    • (2013) Transl Neurodegener , vol.2 , pp. 12
    • McInnes, J.1
  • 19
    • 41449115693 scopus 로고    scopus 로고
    • NIX induces mitochondrial autophagy in reticulocytes
    • 18623629
    • NIX induces mitochondrial autophagy in reticulocytes. Zhang J, Ney PA, Autophagy 2008 4 354 356 18623629
    • (2008) Autophagy , vol.4 , pp. 354-356
    • Zhang, J.1    Ney, P.A.2
  • 20
    • 84858376953 scopus 로고    scopus 로고
    • Mitochondria: In sickness and in health
    • 10.1016/j.cell.2012.02.035 22424226
    • Mitochondria: in sickness and in health. Nunnari J, Suomalainen A, Cell 2012 148 1145 1159 10.1016/j.cell.2012.02.035 22424226
    • (2012) Cell , vol.148 , pp. 1145-1159
    • Nunnari, J.1    Suomalainen, A.2
  • 21
    • 84856951239 scopus 로고    scopus 로고
    • Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition
    • 10.1093/hmg/ddr529 22080835
    • Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition. Gilkerson RW, De Vries RLA, Lebot P, Wikstrom JD, Torgyekes E, Shirihai OS, Przedborski S, Schon EA, Hum Mol Genet 2012 21 978 990 10.1093/hmg/ddr529 22080835
    • (2012) Hum Mol Genet , vol.21 , pp. 978-990
    • Gilkerson, R.W.1    De Vries, R.L.A.2    Lebot, P.3    Wikstrom, J.D.4    Torgyekes, E.5    Shirihai, O.S.6    Przedborski, S.7    Schon, E.A.8
  • 22
    • 84867773087 scopus 로고    scopus 로고
    • Mitophagy: Mechanisms, pathophysiological roles, and analysis
    • 22944659
    • Mitophagy: mechanisms, pathophysiological roles, and analysis. Ding W-X, Yin X-M, Biol Chem 2012 393 547 564 22944659
    • (2012) Biol Chem , vol.393 , pp. 547-564
    • Ding, W.-X.1    Yin, X.-M.2
  • 23
    • 0033523903 scopus 로고    scopus 로고
    • Mitochondrial DNA repairs double-strand breaks in yeast chromosomes
    • 10.1038/47076 10573425
    • Mitochondrial DNA repairs double-strand breaks in yeast chromosomes. Ricchetti M, Fairhead C, Dujon B, Nature 1999 402 96 100 10.1038/47076 10573425
    • (1999) Nature , vol.402 , pp. 96-100
    • Ricchetti, M.1    Fairhead, C.2    Dujon, B.3
  • 24
    • 0028574053 scopus 로고
    • Mitochondrial DNA sequence variation in human evolution and disease
    • 10.1073/pnas.91.19.8739 8090716
    • Mitochondrial DNA sequence variation in human evolution and disease. Wallace DC, Proc Natl Acad Sci USA 1994 91 8739 8746 10.1073/pnas.91.19.8739 8090716
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8739-8746
    • Wallace, D.C.1
  • 25
    • 0030664064 scopus 로고    scopus 로고
    • Mammalian mitochondrial genetics: Heredity, heteroplasmy and disease
    • 10.1016/S0168-9525(97)01266-3 9385842
    • Mammalian mitochondrial genetics: heredity, heteroplasmy and disease. Lightowlers RN, Chinnery PF, Turnbull DM, Howell N, Trends Genet 1997 13 450 455 10.1016/S0168-9525(97)01266-3 9385842
    • (1997) Trends Genet , vol.13 , pp. 450-455
    • Lightowlers, R.N.1    Chinnery, P.F.2    Turnbull, D.M.3    Howell, N.4
  • 26
    • 76749099670 scopus 로고    scopus 로고
    • Zen and the art of mitochondrial DNA maintenance
    • 10.1016/j.tig.2009.12.011 20117854
    • Zen and the art of mitochondrial DNA maintenance. Holt IJ, Trends Genet 2010 26 103 109 10.1016/j.tig.2009.12.011 20117854
    • (2010) Trends Genet , vol.26 , pp. 103-109
    • Holt, I.J.1
  • 27
    • 84866729278 scopus 로고    scopus 로고
    • Minimizing the damage: Repair pathways keep mitochondrial DNA intact
    • 10.1038/nrm3439 22992591
    • Minimizing the damage: repair pathways keep mitochondrial DNA intact. Kazak L, Reyes A, Holt IJ, Nat Rev Mol Cell Biol 2012 13 659 671 10.1038/nrm3439 22992591
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 659-671
    • Kazak, L.1    Reyes, A.2    Holt, I.J.3
  • 28
    • 16844369889 scopus 로고    scopus 로고
    • Nuclear and mitochondrial DNA repair: Similar pathways?
    • 10.1016/j.mito.2005.02.002 16050976
    • Nuclear and mitochondrial DNA repair: similar pathways? Larsen NB, Rasmussen M, Rasmussen LJ, Mitochondrion 2005 5 89 108 10.1016/j.mito.2005.02. 002 16050976
    • (2005) Mitochondrion , vol.5 , pp. 89-108
    • Larsen, N.B.1    Rasmussen, M.2    Rasmussen, L.J.3
  • 29
    • 55049124777 scopus 로고    scopus 로고
    • Long patch base excision repair in mammalian mitochondrial genomes
    • 10.1074/jbc.M803491200 18635552
    • Long patch base excision repair in mammalian mitochondrial genomes. Szczesny B, Tann AW, Longley MJ, Copeland WC, Mitra S, J Biol Chem 2008 283 26349 26356 10.1074/jbc.M803491200 18635552
    • (2008) J Biol Chem , vol.283 , pp. 26349-26356
    • Szczesny, B.1    Tann, A.W.2    Longley, M.J.3    Copeland, W.C.4    Mitra, S.5
  • 31
    • 79551570800 scopus 로고    scopus 로고
    • Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria
    • 10.1073/pnas.1009814107 21041670
    • Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria. Das BB, Dexheimer TS, Maddali K, Pommier Y, Proc Natl Acad Sci USA 2010 107 19790 19795 10.1073/pnas.1009814107 21041670
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 19790-19795
    • Das, B.B.1    Dexheimer, T.S.2    Maddali, K.3    Pommier, Y.4
  • 32
    • 0029911367 scopus 로고    scopus 로고
    • Mammalian mitochondria possess homologous DNA recombination activity
    • 10.1074/jbc.271.44.27536 8910339
    • Mammalian mitochondria possess homologous DNA recombination activity. Thyagarajan B, Padua RA, Campbell C, J Biol Chem 1996 271 27536 27543 10.1074/jbc.271.44.27536 8910339
    • (1996) J Biol Chem , vol.271 , pp. 27536-27543
    • Thyagarajan, B.1    Padua, R.A.2    Campbell, C.3
  • 33
    • 67949099046 scopus 로고    scopus 로고
    • Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks
    • 10.1093/nar/gkp348 19435881
    • Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks. Bacman SR, Williams SL, Moraes CT, Nucleic Acids Res 2009 37 4218 4226 10.1093/nar/gkp348 19435881
    • (2009) Nucleic Acids Res , vol.37 , pp. 4218-4226
    • Bacman, S.R.1    Williams, S.L.2    Moraes, C.T.3
  • 34
    • 0038371133 scopus 로고    scopus 로고
    • Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast
    • 10.1016/S0960-9822(03)00284-7 12725731
    • Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast. Pavlov YI, Mian IM, Kunkel TA, Curr Biol 2003 13 744 748 10.1016/S0960-9822(03)00284-7 12725731
    • (2003) Curr Biol , vol.13 , pp. 744-748
    • Pavlov, Y.I.1    Mian, I.M.2    Kunkel, T.A.3
  • 35
    • 80052698492 scopus 로고    scopus 로고
    • Apoptosis induced by persistent single-strand breaks in mitochondrial genome: Critical role of EXOG (5′-EXO/endonuclease) in their repair
    • 10.1074/jbc.M110.215715 21768646
    • Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5′-EXO/endonuclease) in their repair. Tann AW, Boldogh I, Meiss G, Qian W, Van Houten B, Mitra S, Szczesny B, J Biol Chem 2011 286 31975 31983 10.1074/jbc.M110.215715 21768646
    • (2011) J Biol Chem , vol.286 , pp. 31975-31983
    • Tann, A.W.1    Boldogh, I.2    Meiss, G.3    Qian, W.4    Van Houten, B.5    Mitra, S.6    Szczesny, B.7
  • 37
    • 27144525581 scopus 로고    scopus 로고
    • New mitochondrial carriers: An overview
    • 10.1007/s00018-005-5197-x 16132231
    • New mitochondrial carriers: an overview. Arco AD, Satrústegui J, Cell Mol Life Sci 2005 62 2204 2227 10.1007/s00018-005-5197-x 16132231
    • (2005) Cell Mol Life Sci , vol.62 , pp. 2204-2227
    • Arco, A.D.1    Satrústegui, J.2
  • 38
    • 84867733931 scopus 로고    scopus 로고
    • Cardiac mitochondrial matrix and respiratory complex protein phosphorylation
    • 10.1152/ajpheart.00077.2012 22886415
    • Cardiac mitochondrial matrix and respiratory complex protein phosphorylation. Covian R, Balaban RS, Am J Physiol Heart Circ Physiol 2012 303 940 H966 10.1152/ajpheart.00077.2012 22886415
    • (2012) Am J Physiol Heart Circ Physiol , vol.303
    • Covian, R.1    Balaban, R.S.2
  • 39
    • 84863518019 scopus 로고    scopus 로고
    • Mitochondrial Ca§ssup§2+§esup§ homeostasis: Mechanism, role, and tissue specificities
    • 10.1007/s00424-012-1122-y 22706634
    • Mitochondrial Ca§ssup§2+§esup§ homeostasis: mechanism, role, and tissue specificities. Pizzo P, Drago I, Filadi R, Pozzan T, Pflugers Arch 2012 464 3 17 10.1007/s00424-012-1122-y 22706634
    • (2012) Pflugers Arch , vol.464 , pp. 3-17
    • Pizzo, P.1    Drago, I.2    Filadi, R.3    Pozzan, T.4
  • 41
    • 84866728707 scopus 로고    scopus 로고
    • Endoplasmic reticulum-mitochondria contacts: Function of the junction
    • 10.1038/nrm3440 22992592
    • Endoplasmic reticulum-mitochondria contacts: function of the junction. Rowland AA, Voeltz GK, Nat Rev Mol Cell Biol 2012 13 607 625 10.1038/nrm3440 22992592
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 607-625
    • Rowland, A.A.1    Voeltz, G.K.2
  • 42
    • 78651287877 scopus 로고    scopus 로고
    • Making heads or tails of phospholipids in mitochondria
    • 10.1083/jcb.201006159 21220505
    • Making heads or tails of phospholipids in mitochondria. Osman C, Voelker DR, Langer T, J Cell Biol 2011 192 7 16 10.1083/jcb.201006159 21220505
    • (2011) J Cell Biol , vol.192 , pp. 7-16
    • Osman, C.1    Voelker, D.R.2    Langer, T.3
  • 43
    • 38549173564 scopus 로고    scopus 로고
    • Membrane lipids: Where they are and how they behave
    • 10.1038/nrm2330 18216768
    • Membrane lipids: where they are and how they behave. van Meer G, Voelker DR, Feigenson GW, Nat Rev Mol Cell Biol 2008 9 112 124 10.1038/nrm2330 18216768
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 112-124
    • Van Meer, G.1    Voelker, D.R.2    Feigenson, G.W.3
  • 44
    • 57349100367 scopus 로고    scopus 로고
    • Mitofusin 2 tethers endoplasmic reticulum to mitochondria
    • 10.1038/nature07534 19052620
    • Mitofusin 2 tethers endoplasmic reticulum to mitochondria. de Brito OM, Scorrano L, Nature 2008 456 605 610 10.1038/nature07534 19052620
    • (2008) Nature , vol.456 , pp. 605-610
    • De Brito, O.M.1    Scorrano, L.2
  • 45
    • 0032511112 scopus 로고    scopus 로고
    • Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses
    • 10.1126/science.280.5370.1763 9624056
    • Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses. Rizzuto R, Pinton P, Carrington W, Fay FS, Fogarty KE, Lifshitz LM, Tuft RA, Pozzan T, Science 1998 280 1763 1766 10.1126/science.280.5370.1763 9624056
    • (1998) Science , vol.280 , pp. 1763-1766
    • Rizzuto, R.1    Pinton, P.2    Carrington, W.3    Fay, F.S.4    Fogarty, K.E.5    Lifshitz, L.M.6    Tuft, R.A.7    Pozzan, T.8
  • 46
    • 0036877142 scopus 로고    scopus 로고
    • The endoplasmic reticulum: A multifunctional signaling organelle
    • 10.1016/S0143416002001823 12543086
    • The endoplasmic reticulum: a multifunctional signaling organelle. Berridge MJ, Cell Calcium 2002 32 235 249 10.1016/S0143416002001823 12543086
    • (2002) Cell Calcium , vol.32 , pp. 235-249
    • Berridge, M.J.1
  • 47
    • 84865427488 scopus 로고    scopus 로고
    • Mitochondria as sensors and regulators of calcium signalling
    • 10.1038/nrm3412 22850819
    • Mitochondria as sensors and regulators of calcium signalling. Rizzuto R, De Stefani D, Raffaello A, Mammucari C, Nat Rev Mol Cell Biol 2012 13 566 578 10.1038/nrm3412 22850819
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 566-578
    • Rizzuto, R.1    De Stefani, D.2    Raffaello, A.3    Mammucari, C.4
  • 48
    • 84863530065 scopus 로고    scopus 로고
    • Endoplasmic reticulum-mitochondria coupling: Local Ca§ssup§ 2+§esup§ signalling with functional consequences
    • 10.1007/s00424-012-1095-x 22415215
    • Endoplasmic reticulum-mitochondria coupling: local Ca§ssup§ 2+§esup§ signalling with functional consequences. Bakowski D, Nelson C, Parekh AB, Pflugers Arch 2012 464 27 32 10.1007/s00424-012-1095-x 22415215
    • (2012) Pflugers Arch , vol.464 , pp. 27-32
    • Bakowski, D.1    Nelson, C.2    Parekh, A.B.3
  • 49
    • 0037417334 scopus 로고    scopus 로고
    • Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
    • 10.1083/jcb.200212059 12668660
    • Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. Breckenridge DG, Stojanovic M, Marcellus RC, Shore GC, J Cell Biol 2003 160 1115 1127 10.1083/jcb.200212059 12668660
    • (2003) J Cell Biol , vol.160 , pp. 1115-1127
    • Breckenridge, D.G.1    Stojanovic, M.2    Marcellus, R.C.3    Shore, G.C.4
  • 50
    • 68949192292 scopus 로고    scopus 로고
    • Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles
    • 10.1016/j.biocel.2009.02.017 19703651
    • Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles. Lebiedzinska M, Szabadkai G, Jones AWE, Duszynski J, Wieckowski MR, Int J Biochem Cell Biol 2009 41 1805 1816 10.1016/j.biocel.2009.02.017 19703651
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 1805-1816
    • Lebiedzinska, M.1    Szabadkai, G.2    Jones, A.W.E.3    Duszynski, J.4    Wieckowski, M.R.5
  • 51
    • 33846212708 scopus 로고    scopus 로고
    • Safe and effective use of the ketogenic diet in children with epilepsy and mitochondrial respiratory chain complex defects
    • Safe and effective use of the ketogenic diet in children with epilepsy and mitochondrial respiratory chain complex defects. Kang H-C, Lee Y-M, Kim HD, Lee JS, Slama A, Epilepsia 2007 48 82 88
    • (2007) Epilepsia , vol.48 , pp. 82-88
    • Kang, H.-C.1    Lee, Y.-M.2    Kim, H.D.3    Lee, J.S.4    Slama, A.5
  • 52
    • 9144268527 scopus 로고    scopus 로고
    • Ketogenic treatment reduces deleted mitochondrial DNAs in cultured human cells
    • 10.1002/ana.20240 15389892
    • Ketogenic treatment reduces deleted mitochondrial DNAs in cultured human cells. Santra S, Gilkerson RW, Davidson M, Schon EA, Ann Neurol 2004 56 662 669 10.1002/ana.20240 15389892
    • (2004) Ann Neurol , vol.56 , pp. 662-669
    • Santra, S.1    Gilkerson, R.W.2    Davidson, M.3    Schon, E.A.4
  • 54
    • 84887020874 scopus 로고    scopus 로고
    • Diet influences the intake target and mitochondrial functions of Drosophila melanogaster males
    • in press
    • Diet influences the intake target and mitochondrial functions of Drosophila melanogaster males. Pichaud N, Messmer M, Correa CC, Ballard JWO, Mitochondrion 2013 in press
    • (2013) Mitochondrion
    • Pichaud, N.1    Messmer, M.2    Correa, C.C.3    Ballard, J.W.O.4
  • 55
    • 84860698221 scopus 로고    scopus 로고
    • Epilepsy in mitochondrial disorders
    • 10.1016/j.seizure.2012.03.003 22459315
    • Epilepsy in mitochondrial disorders. Finsterer J, Zarrouk Mahjoub S, Seizure 2012 21 316 321 10.1016/j.seizure.2012.03.003 22459315
    • (2012) Seizure , vol.21 , pp. 316-321
    • Finsterer, J.1    Zarrouk Mahjoub, S.2
  • 56
    • 0033047456 scopus 로고    scopus 로고
    • Gene shifting: A novel therapy for mitochondrial myopathy
    • 10.1093/hmg/8.6.1047 10332036
    • Gene shifting: a novel therapy for mitochondrial myopathy. Taivassalo T, Fu K, Johns T, Arnold D, Karpati G, Shoubridge EA, Hum Mol Genet 1999 8 1047 1052 10.1093/hmg/8.6.1047 10332036
    • (1999) Hum Mol Genet , vol.8 , pp. 1047-1052
    • Taivassalo, T.1    Fu, K.2    Johns, T.3    Arnold, D.4    Karpati, G.5    Shoubridge, E.A.6
  • 57
    • 0031900991 scopus 로고    scopus 로고
    • The myoclonic epilepsy and ragged-red fiber mutation provides new insights into human mitochondrial function and genetics
    • 10.1086/301813 9529371
    • The myoclonic epilepsy and ragged-red fiber mutation provides new insights into human mitochondrial function and genetics. Chomyn A, Am J Hum Genet 1998 62 745 751 10.1086/301813 9529371
    • (1998) Am J Hum Genet , vol.62 , pp. 745-751
    • Chomyn, A.1
  • 60
    • 84872199499 scopus 로고    scopus 로고
    • Diagnosis and treatment of mitochondrial myopathies
    • 10.3109/07853890.2011.605389 21867371
    • Diagnosis and treatment of mitochondrial myopathies. Pfeffer G, Chinnery PF, Ann Med 2013 45 4 16 10.3109/07853890.2011.605389 21867371
    • (2013) Ann Med , vol.45 , pp. 4-16
    • Pfeffer, G.1    Chinnery, P.F.2
  • 61
    • 77951877242 scopus 로고    scopus 로고
    • Metabolic acidosis: Pathophysiology, diagnosis and management
    • Metabolic acidosis: pathophysiology, diagnosis and management. Kraut JA, Madias NE, Nat Publ Group 2010 6 274 285
    • (2010) Nat Publ Group , vol.6 , pp. 274-285
    • Kraut, J.A.1    Madias, N.E.2
  • 62
    • 84879005136 scopus 로고    scopus 로고
    • Metformin-associated lactic acidosis requiring hospitalization. A national 10 year survey and a systematic literature review
    • 23436666
    • Metformin-associated lactic acidosis requiring hospitalization. A national 10 year survey and a systematic literature review. Renda F, Mura P, Finco G, Ferrazin F, Pani L, Landoni G, Eur Rev Med Pharmacol Sci 2013 17 Suppl 1 45 49 23436666
    • (2013) Eur Rev Med Pharmacol Sci , vol.17 , Issue.SUPPL. 1 , pp. 45-49
    • Renda, F.1    Mura, P.2    Finco, G.3    Ferrazin, F.4    Pani, L.5    Landoni, G.6
  • 63
    • 0033976601 scopus 로고    scopus 로고
    • Sodium bicarbonate for the treatment of lactic acidosis
    • 10.1378/chest.117.1.260 10631227
    • Sodium bicarbonate for the treatment of lactic acidosis. Forsythe SM, Schmidt GA, Chest 2000 117 260 267 10.1378/chest.117.1.260 10631227
    • (2000) Chest , vol.117 , pp. 260-267
    • Forsythe, S.M.1    Schmidt, G.A.2
  • 64
    • 0035140640 scopus 로고    scopus 로고
    • Lactic acidosis update for critical care clinicians
    • 11251027
    • Lactic acidosis update for critical care clinicians. Luft FC, J Am Soc Nephrol 2001 12 Suppl 17 15 S19 11251027
    • (2001) J Am Soc Nephrol , vol.12 , Issue.SUPPL. 17
    • Luft, F.C.1
  • 65
    • 0021143782 scopus 로고
    • Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: A distinctive clinical syndrome
    • 10.1002/ana.410160409 6093682
    • Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: a distinctive clinical syndrome. Pavlakis SG, Phillips PC, DiMauro S, De Vivo DC, Rowland LP, Ann Neurol 1984 16 481 488 10.1002/ana.410160409 6093682
    • (1984) Ann Neurol , vol.16 , pp. 481-488
    • Pavlakis, S.G.1    Phillips, P.C.2    Dimauro, S.3    De Vivo, D.C.4    Rowland, L.P.5
  • 67
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human disease
    • 15861210
    • Mitochondrial DNA mutations in human disease. Taylor RW, Turnbull DM, Nat Rev Genet 2005 6 389 402 15861210
    • (2005) Nat Rev Genet , vol.6 , pp. 389-402
    • Taylor, R.W.1    Turnbull, D.M.2
  • 68
    • 1642287689 scopus 로고    scopus 로고
    • Metabolism and function of coenzyme Q
    • 10.1016/j.bbamem.2003.11.012 14757233
    • Metabolism and function of coenzyme Q. Turunen M, Olsson J, Dallner G, Biochim Biophys Acta 2004 1660 171 199 10.1016/j.bbamem.2003.11.012 14757233
    • (2004) Biochim Biophys Acta , vol.1660 , pp. 171-199
    • Turunen, M.1    Olsson, J.2    Dallner, G.3
  • 69
    • 84859436493 scopus 로고
    • CoQ(10) deficiencies and MNGIE: Two treatable mitochondrial disorders
    • CoQ(10) deficiencies and MNGIE: two treatable mitochondrial disorders. Hirano M, Garone C, Quinzii CM, Biochim Biophys Acta 1820 2012 625 631
    • (1820) Biochim Biophys Acta , vol.2012 , pp. 625-631
    • Hirano, M.1    Garone, C.2    Quinzii, C.M.3
  • 71
    • 80054861726 scopus 로고    scopus 로고
    • Primary and secondary CoQ(10) deficiencies in humans
    • 10.1002/biof.155 21990098
    • Primary and secondary CoQ(10) deficiencies in humans. Quinzii CM, Hirano M, Biofactors 2011 37 361 365 10.1002/biof.155 21990098
    • (2011) Biofactors , vol.37 , pp. 361-365
    • Quinzii, C.M.1    Hirano, M.2
  • 74
    • 77954035632 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion syndromes-many genes, common mechanisms
    • 10.1016/j.nmd.2010.03.017 20444604
    • Mitochondrial DNA depletion syndromes-many genes, common mechanisms. Suomalainen A, Isohanni P, Neuromuscul Disord 2010 20 429 437 10.1016/j.nmd.2010.03.017 20444604
    • (2010) Neuromuscul Disord , vol.20 , pp. 429-437
    • Suomalainen, A.1    Isohanni, P.2
  • 75
    • 0033613865 scopus 로고    scopus 로고
    • Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder
    • 10.1126/science.283.5402.689 9924029
    • Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder. Nishino I, Spinazzola A, Hirano M, Science 1999 283 689 692 10.1126/science.283.5402.689 9924029
    • (1999) Science , vol.283 , pp. 689-692
    • Nishino, I.1    Spinazzola, A.2    Hirano, M.3
  • 76
    • 81055133547 scopus 로고    scopus 로고
    • Clinical and genetic spectrum of mitochondrial neurogastrointestinal encephalomyopathy
    • 10.1093/brain/awr245 21933806
    • Clinical and genetic spectrum of mitochondrial neurogastrointestinal encephalomyopathy. Garone C, Tadesse S, Hirano M, Brain 2011 134 3326 3332 10.1093/brain/awr245 21933806
    • (2011) Brain , vol.134 , pp. 3326-3332
    • Garone, C.1    Tadesse, S.2    Hirano, M.3
  • 77
    • 1642451711 scopus 로고    scopus 로고
    • Definitive diagnosis of mitochondrial neurogastrointestinal encephalomyopathy by biochemical assays
    • 10.1373/clinchem.2003.026179 14633909
    • Definitive diagnosis of mitochondrial neurogastrointestinal encephalomyopathy by biochemical assays. Martí R, Spinazzola A, Tadesse S, Nishino I, Nishigaki Y, Hirano M, Clin Chem 2004 50 120 124 10.1373/clinchem.2003.026179 14633909
    • (2004) Clin Chem , vol.50 , pp. 120-124
    • Martí, R.1    Spinazzola, A.2    Tadesse, S.3    Nishino, I.4    Nishigaki, Y.5    Hirano, M.6
  • 78
    • 0242582958 scopus 로고    scopus 로고
    • Deoxyribonucleotide pool imbalance stimulates deletions in HeLa cell mitochondrial DNA
    • 10.1074/jbc.C300401200 13679382
    • Deoxyribonucleotide pool imbalance stimulates deletions in HeLa cell mitochondrial DNA. Song S, Wheeler LJ, Mathews CK, J Biol Chem 2003 278 43893 43896 10.1074/jbc.C300401200 13679382
    • (2003) J Biol Chem , vol.278 , pp. 43893-43896
    • Song, S.1    Wheeler, L.J.2    Mathews, C.K.3
  • 79
    • 33745783923 scopus 로고    scopus 로고
    • Pre- and post-dialysis quantitative dosage of thymidine in urine and plasma of a MNGIE patient by using HPLC-ESI-MS/MS
    • 10.1002/jms.1013 16498612
    • Pre- and post-dialysis quantitative dosage of thymidine in urine and plasma of a MNGIE patient by using HPLC-ESI-MS/MS. la Marca G, Malvagia S, Casetta B, Pasquini E, Pela I, Hirano M, Donati MA, Zammarchi E, J Mass Spectrom 2006 41 586 592 10.1002/jms.1013 16498612
    • (2006) J Mass Spectrom , vol.41 , pp. 586-592
    • La Marca, G.1    Malvagia, S.2    Casetta, B.3    Pasquini, E.4    Pela, I.5    Hirano, M.6    Donati, M.A.7    Zammarchi, E.8
  • 81
    • 33749001168 scopus 로고    scopus 로고
    • Mitochondrial DNA polymerase-gamma and human disease
    • 16987890
    • Mitochondrial DNA polymerase-gamma and human disease. Hudson G, Chinnery PF, Hum Mol Genet 2006 15 2 244 R252 16987890
    • (2006) Hum Mol Genet , vol.15 , Issue.2
    • Hudson, G.1    Chinnery, P.F.2
  • 82
    • 79960801633 scopus 로고    scopus 로고
    • Mitochondrial disorders of DNA polymerase γ dysfunction: From anatomic to molecular pathology diagnosis
    • 21732785
    • Mitochondrial disorders of DNA polymerase γ dysfunction: from anatomic to molecular pathology diagnosis. Zhang L, Chan SSL, Wolff DJ, Arch Pathol Lab Med 2011 135 925 934 21732785
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 925-934
    • Zhang, L.1    Chan, S.S.L.2    Wolff, D.J.3
  • 83
    • 35649024143 scopus 로고    scopus 로고
    • Recessive Twinkle mutations in early onset encephalopathy with mtDNA depletion
    • 10.1093/brain/awm242 17921179
    • Recessive Twinkle mutations in early onset encephalopathy with mtDNA depletion. Hakonen AH, Isohanni P, Paetau A, Herva R, Suomalainen A, Lönnqvist T, Brain 2007 130 3032 3040 10.1093/brain/awm242 17921179
    • (2007) Brain , vol.130 , pp. 3032-3040
    • Hakonen, A.H.1    Isohanni, P.2    Paetau, A.3    Herva, R.4    Suomalainen, A.5    Lönnqvist, T.6
  • 84
    • 41549151612 scopus 로고    scopus 로고
    • 155th ENMC workshop: Polymerase gamma and disorders of mitochondrial DNA synthesis, 21-23 September 2007, Naarden, the Netherlands
    • 10.1016/j.nmd.2007.11.005 18160290
    • 155th ENMC workshop: polymerase gamma and disorders of mitochondrial DNA synthesis, 21-23 September 2007, Naarden, The Netherlands. Chinnery PF, Zeviani M, Neuromuscul Disord 2008 18 259 267 10.1016/j.nmd.2007.11.005 18160290
    • (2008) Neuromuscul Disord , vol.18 , pp. 259-267
    • Chinnery, P.F.1    Zeviani, M.2
  • 85
    • 77955269817 scopus 로고    scopus 로고
    • The clinical diagnosis of POLG disease and other mitochondrial DNA depletion disorders
    • 10.1016/j.ymeth.2010.05.008 20558295
    • The clinical diagnosis of POLG disease and other mitochondrial DNA depletion disorders. Cohen BH, Naviaux RK, Methods 2010 51 364 373 10.1016/j.ymeth.2010.05.008 20558295
    • (2010) Methods , vol.51 , pp. 364-373
    • Cohen, B.H.1    Naviaux, R.K.2
  • 86
    • 83755205842 scopus 로고    scopus 로고
    • Defects in mitochondrial DNA replication and human disease
    • 10.3109/10409238.2011.632763 22176657
    • Defects in mitochondrial DNA replication and human disease. Copeland WC, Crit Rev Biochem Mol Biol 2012 47 64 74 10.3109/10409238.2011.632763 22176657
    • (2012) Crit Rev Biochem Mol Biol , vol.47 , pp. 64-74
    • Copeland, W.C.1
  • 87
    • 84858702540 scopus 로고    scopus 로고
    • The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives
    • The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives. Chen L, Magliano DJ, Zimmet PZ, Nat Rev Endocrinol 2012 8 228 236
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 228-236
    • Chen, L.1    Magliano, D.J.2    Zimmet, P.Z.3
  • 88
    • 0028342686 scopus 로고
    • Mechanisms of fatty acid-induced inhibition of glucose uptake
    • 10.1172/JCI117252 8200979
    • Mechanisms of fatty acid-induced inhibition of glucose uptake. Boden G, Chen X, Ruiz J, White JV, Rossetti L, J Clin Invest 1994 93 2438 2446 10.1172/JCI117252 8200979
    • (1994) J Clin Invest , vol.93 , pp. 2438-2446
    • Boden, G.1    Chen, X.2    Ruiz, J.3    White, J.V.4    Rossetti, L.5
  • 91
    • 0033595684 scopus 로고    scopus 로고
    • Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication
    • 10.1126/science.286.5440.774 10531063
    • Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication. Michikawa Y, Mazzucchelli F, Bresolin N, Scarlato G, Attardi G, Science 1999 286 774 779 10.1126/science.286.5440.774 10531063
    • (1999) Science , vol.286 , pp. 774-779
    • Michikawa, Y.1    Mazzucchelli, F.2    Bresolin, N.3    Scarlato, G.4    Attardi, G.5
  • 92
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • 10.2337/diabetes.51.10.2944 12351431
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Kelley DE, He J, Menshikova EV, Ritov VB, Diabetes 2002 51 2944 2950 10.2337/diabetes.51.10.2944 12351431
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 94
    • 0028365102 scopus 로고
    • Maternally inherited diabetes and deafness is a distinct subtype of diabetes and associates with a single point mutation in the mitochondrial tRNA(Leu(UUR)) gene
    • 10.2337/diab.43.6.746 7910800
    • Maternally inherited diabetes and deafness is a distinct subtype of diabetes and associates with a single point mutation in the mitochondrial tRNA(Leu(UUR)) gene. van den Ouweland JM, Lemkes HH, Trembath RC, Ross R, Velho G, Cohen D, Froguel P, Maassen JA, Diabetes 1994 43 746 751 10.2337/diab.43.6. 746 7910800
    • (1994) Diabetes , vol.43 , pp. 746-751
    • Van Den Ouweland, J.M.1    Lemkes, H.H.2    Trembath, R.C.3    Ross, R.4    Velho, G.5    Cohen, D.6    Froguel, P.7    Maassen, J.A.8
  • 95
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • 10.1126/science.1104343 15662004
    • Mitochondrial dysfunction and type 2 diabetes. Lowell BB, Shulman GI, Science 2005 307 384 387 10.1126/science.1104343 15662004
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 96
    • 77954859197 scopus 로고    scopus 로고
    • The role of mitochondria in the pathogenesis of type 2 diabetes
    • 10.1210/er.2009-0027 20156986
    • The role of mitochondria in the pathogenesis of type 2 diabetes. Patti M-E, Corvera S, Endocr Rev 2010 31 364 395 10.1210/er.2009-0027 20156986
    • (2010) Endocr Rev , vol.31 , pp. 364-395
    • Patti, M.-E.1    Corvera, S.2
  • 97
    • 79955835149 scopus 로고    scopus 로고
    • Mitochondrial subversion in cancer
    • 10.1158/1940-6207.CAPR-10-0326
    • Mitochondrial subversion in cancer. Chatterjee A, Dasgupta S, Sidransky D, Canc Prev Res (Phila) 2011 4 638 654 10.1158/1940-6207.CAPR-10-0326
    • (2011) Canc Prev Res (Phila) , vol.4 , pp. 638-654
    • Chatterjee, A.1    Dasgupta, S.2    Sidransky, D.3
  • 99
    • 57349183018 scopus 로고    scopus 로고
    • Low copy number and low oxidative damage of mitochondrial DNA are associated with tumor progression in lung cancer tissues after neoadjuvant chemotherapy
    • 10.1510/icvts.2008.177006 18685121
    • Low copy number and low oxidative damage of mitochondrial DNA are associated with tumor progression in lung cancer tissues after neoadjuvant chemotherapy. Lin C-S, Wang L-S, Tsai C-M, Wei Y-H, Interact Cardiovasc Thorac Surg 2008 7 954 958 10.1510/icvts.2008.177006 18685121
    • (2008) Interact Cardiovasc Thorac Surg , vol.7 , pp. 954-958
    • Lin, C.-S.1    Wang, L.-S.2    Tsai, C.-M.3    Wei, Y.-H.4
  • 101
    • 34547218569 scopus 로고    scopus 로고
    • Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients
    • 10.1080/15216540701509955 17654121
    • Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients. Yu M, Zhou Y, Shi Y, Ning L, Yang Y, Wei X, Zhang N, Hao X, Niu R, IUBMB Life 2007 59 450 457 10.1080/15216540701509955 17654121
    • (2007) IUBMB Life , vol.59 , pp. 450-457
    • Yu, M.1    Zhou, Y.2    Shi, Y.3    Ning, L.4    Yang, Y.5    Wei, X.6    Zhang, N.7    Hao, X.8    Niu, R.9
  • 103
    • 84869080120 scopus 로고    scopus 로고
    • Mitochondria: One of the destinations of miRNAs
    • 10.1016/j.mito.2012.10.009 23085198
    • Mitochondria: one of the destinations of miRNAs. Sripada L, Tomar D, Singh R, Mitochondrion 2012 12 593 599 10.1016/j.mito.2012.10.009 23085198
    • (2012) Mitochondrion , vol.12 , pp. 593-599
    • Sripada, L.1    Tomar, D.2    Singh, R.3
  • 104
    • 84878975272 scopus 로고    scopus 로고
    • The role of microRNAs in mitochondria in cancer
    • 10.1016/j.canlet.2013.05.001
    • The role of microRNAs in mitochondria in cancer. Bienertova-Vasku J, Sana J, Slaby O, Canc Lett 2013 336 1 7 10.1016/j.canlet.2013.05.001
    • (2013) Canc Lett , vol.336 , pp. 1-7
    • Bienertova-Vasku, J.1    Sana, J.2    Slaby, O.3
  • 105
    • 77956586695 scopus 로고    scopus 로고
    • Mitochondria in heart failure
    • 10.1093/cvr/cvq240 20668004
    • Mitochondria in heart failure. Rosca MG, Hoppel CL, Cardiovasc Res 2010 88 40 50 10.1093/cvr/cvq240 20668004
    • (2010) Cardiovasc Res , vol.88 , pp. 40-50
    • Rosca, M.G.1    Hoppel, C.L.2
  • 106
    • 0033951542 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in heart failure: Potential for therapeutic interventions?
    • 10.1016/S0008-6363(99)00419-8 10728404
    • Mitochondrial dysfunction in heart failure: potential for therapeutic interventions? Stanley WC, Hoppel CL, Cardiovasc Res 2000 45 805 806 10.1016/S0008-6363(99)00419-8 10728404
    • (2000) Cardiovasc Res , vol.45 , pp. 805-806
    • Stanley, W.C.1    Hoppel, C.L.2
  • 108
    • 24144493814 scopus 로고    scopus 로고
    • Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
    • 10.1016/j.cmet.2005.05.001 16054089
    • Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Guzy RD, Hoyos B, Robin E, Chen H, Liu L, Mansfield KD, Simon MC, Hammerling U, Schumacker PT, Cell Metab 2005 1 401 408 10.1016/j.cmet.2005.05.001 16054089
    • (2005) Cell Metab , vol.1 , pp. 401-408
    • Guzy, R.D.1    Hoyos, B.2    Robin, E.3    Chen, H.4    Liu, L.5    Mansfield, K.D.6    Simon, M.C.7    Hammerling, U.8    Schumacker, P.T.9
  • 109
    • 37349066205 scopus 로고    scopus 로고
    • Mitochondria and heart failure
    • 10.1097/MCO.0b013e3282f0ecbe 18089951
    • Mitochondria and heart failure. Murray AJ, Edwards LM, Clarke K, Curr Opin Clin Nutr Metab Care 2007 10 704 711 10.1097/MCO.0b013e3282f0ecbe 18089951
    • (2007) Curr Opin Clin Nutr Metab Care , vol.10 , pp. 704-711
    • Murray, A.J.1    Edwards, L.M.2    Clarke, K.3
  • 110
    • 79957764437 scopus 로고    scopus 로고
    • Mitochondria-targeted antioxidants as therapies
    • 21356165
    • Mitochondria-targeted antioxidants as therapies. Smith RAJ, Murphy MP, Discov Med 2011 11 106 114 21356165
    • (2011) Discov Med , vol.11 , pp. 106-114
    • Smith, R.A.J.1    Murphy, M.P.2
  • 111
    • 79959919415 scopus 로고    scopus 로고
    • Therapeutic action of the mitochondria-targeted antioxidant SkQ1 on retinopathy in OXYS rats linked with improvement of VEGF and PEDF gene expression
    • 10.1371/journal.pone.0021682 21750722
    • Therapeutic action of the mitochondria-targeted antioxidant SkQ1 on retinopathy in OXYS rats linked with improvement of VEGF and PEDF gene expression. Markovets AM, Fursova AZ, Kolosova NG, PLoS ONE 2011 6 21682 10.1371/journal.pone.0021682 21750722
    • (2011) PLoS ONE , vol.6 , pp. 521682
    • Markovets, A.M.1    Fursova, A.Z.2    Kolosova, N.G.3
  • 113
    • 84873413349 scopus 로고    scopus 로고
    • Mitochondria as a therapeutic target in heart failure
    • 10.1016/j.jacc.2012.08.1021 23219298
    • Mitochondria as a therapeutic target in heart failure. Bayeva M, Gheorghiade M, Ardehali H, J Am Coll Cardiol 2013 61 599 610 10.1016/j.jacc.2012.08.1021 23219298
    • (2013) J Am Coll Cardiol , vol.61 , pp. 599-610
    • Bayeva, M.1    Gheorghiade, M.2    Ardehali, H.3
  • 114
    • 77953290939 scopus 로고    scopus 로고
    • Therapeutic prospects for mitochondrial disease
    • 10.1016/j.molmed.2010.04.007 20556877
    • Therapeutic prospects for mitochondrial disease. Schon EA, DiMauro S, Hirano M, Gilkerson RW, Trends Mol Med 2010 16 268 276 10.1016/j.molmed.2010.04. 007 20556877
    • (2010) Trends Mol Med , vol.16 , pp. 268-276
    • Schon, E.A.1    Dimauro, S.2    Hirano, M.3    Gilkerson, R.W.4
  • 115
    • 79959895924 scopus 로고    scopus 로고
    • Therapy for mitochondrial disorders: Little proof, high research activity, some promise
    • 10.1016/j.siny.2011.05.003 21676668
    • Therapy for mitochondrial disorders: little proof, high research activity, some promise. Suomalainen A, Semin Fetal Neonatal Med 2011 16 236 240 10.1016/j.siny.2011.05.003 21676668
    • (2011) Semin Fetal Neonatal Med , vol.16 , pp. 236-240
    • Suomalainen, A.1


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