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Volumn 169, Issue 3, 2013, Pages 276-288

DNA delivery with hyperbranched polylysine: A comparative study with linear and dendritic polylysine

Author keywords

Dendrimer; Hyperbranched polymer; Non viral gene delivery; Polylysine; Trafficking; Transient gene expression

Indexed keywords

AMINO ACIDS; CYTOLOGY; DRUG THERAPY; GENE EXPRESSION; GENE TRANSFER; GENES; MOLECULAR BIOLOGY; MOLECULAR WEIGHT; POLYMER BLENDS;

EID: 84885174223     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.01.019     Document Type: Article
Times cited : (114)

References (49)
  • 1
    • 0003008343 scopus 로고    scopus 로고
    • Synthetic DNA delivery systems
    • DOI 10.1038/71889
    • D. Luo, W.M. Saltzman, Synthetic DNA delivery systems, Nat. Biotechnol. 18 (2000) 33-37. (Pubitemid 30041168)
    • (2000) Nature Biotechnology , vol.18 , Issue.1 , pp. 33-37
    • Lou, D.1    Saltzman, W.M.2
  • 2
    • 33744805790 scopus 로고    scopus 로고
    • Polymers for gene delivery across length scales
    • DOI 10.1038/nmat1645, PII N1645
    • D. Putnam, Polymers for gene delivery across length scales, Nat. Mater. 5 (2006) 439-451. (Pubitemid 43838906)
    • (2006) Nature Materials , vol.5 , Issue.6 , pp. 439-451
    • Putnam, D.1
  • 3
    • 60149095412 scopus 로고    scopus 로고
    • Gene transfer to the lung: Lessons learned from more than 2 decades of CF gene therapy
    • U. Griesenbach, E.W.F.W. Alton, Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy, Adv. Drug Deliv. Rev. 61 (2009) 128-139.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 128-139
    • Griesenbach, U.1    Alton, E.W.F.W.2
  • 4
    • 58749101153 scopus 로고    scopus 로고
    • Reflections on more than 10 years of TGE approaches
    • S. Geisse, Reflections on more than 10 years of TGE approaches, Protein Expr. Purif. 64 (2009) 99-107.
    • (2009) Protein Expr. Purif. , vol.64 , pp. 99-107
    • Geisse, S.1
  • 5
    • 36148942092 scopus 로고    scopus 로고
    • Breaking the bottleneck: Eukaryotic membrane protein expression for high-resolution structural studies
    • DOI 10.1016/j.jsb.2007.07.001, PII S1047847707001505, Electron Crystallography of Membrane Proteins
    • C.R. Midgett, D.R. Madden, Breaking the bottleneck: eukaryotic membrane protein expression for high-resolution structural studies, J. Struct. Biol. 160 (2007) 265-274. (Pubitemid 350103823)
    • (2007) Journal of Structural Biology , vol.160 , Issue.3 , pp. 265-274
    • Midgett, C.R.1    Madden, D.R.2
  • 6
    • 22144447455 scopus 로고    scopus 로고
    • Design and development of polymers for gene delivery
    • DOI 10.1038/nrd1775
    • D.W. Pack, A.S. Hoffman, S. Pun, P.S. Stayton, Design and development of polymers for gene delivery, Nat. Rev. Drug Discov. 4 (2005) 581-593. (Pubitemid 40975711)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.7 , pp. 581-593
    • Pack, D.W.1    Hoffman, A.S.2    Pun, S.3    Stayton, P.S.4
  • 7
    • 33745460260 scopus 로고    scopus 로고
    • Current status of polymeric gene delivery systems
    • DOI 10.1016/j.addr.2006.03.007, PII S0169409X06000500
    • T.G. Park, J.H. Jeong, S.W. Kim, Current status of polymeric gene delivery systems, Adv. Drug Deliv. Rev. 58 (2006) 467-486. (Pubitemid 43949425)
    • (2006) Advanced Drug Delivery Reviews , vol.58 , Issue.4 , pp. 467-486
    • Park, T.G.1    Jeong, J.H.2    Kim, S.W.3
  • 8
    • 14044272234 scopus 로고    scopus 로고
    • Structure/property studies of polymeric gene delivery using a library of poly(β-amino esters)
    • DOI 10.1016/j.ymthe.2004.11.015, PII S1525001604015643
    • D.G. Anderson, A. Akinc, N. Hossain, R. Langer, Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters), Mol. Ther. 11 (2005) 426-434. (Pubitemid 40277319)
    • (2005) Molecular Therapy , vol.11 , Issue.3 , pp. 426-434
    • Anderson, D.G.1    Akinc, A.2    Hossain, N.3    Langer, R.4
  • 9
    • 61649104319 scopus 로고    scopus 로고
    • Combinatorial evaluation of cations, pH-sensitive and hydrophobic moieties for polymeric vector design
    • S.Y. Wong, N. Sood, D. Putnam, Combinatorial evaluation of cations, pH-sensitive and hydrophobic moieties for polymeric vector design, Mol. Ther. 17 (2009) 480-490.
    • (2009) Mol. Ther. , vol.17 , pp. 480-490
    • Wong, S.Y.1    Sood, N.2    Putnam, D.3
  • 10
    • 33847120795 scopus 로고    scopus 로고
    • Biodistribution and tissue expression kinetics of plasmid DNA complexed with polyethylenimines of different molecular weight and structure
    • DOI 10.1016/j.jconrel.2006.12.009, PII S0168365906007061
    • G.-J. Jeong, H.-M. Byun, J.M. Kim, H. Yoon, H.-G. Choi, W.-K. Kim, S.-J. Kim, Y.-K. Oh, Biodistribution and tissue expression kinetics of plasmid DNA complexed with polyethylenimines of different molecular weight and structure, J. Control. Release 118 (2007) 118-125. (Pubitemid 46283104)
    • (2007) Journal of Controlled Release , vol.118 , Issue.1 , pp. 118-125
    • Jeong, G.-J.1    Byun, H.-M.2    Kim, J.M.3    Yoon, H.4    Choi, H.-G.5    Kim, W.-K.6    Kim, S.-J.7    Oh, Y.-K.8
  • 11
    • 0033394513 scopus 로고    scopus 로고
    • Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs
    • DOI 10.1038/sj.gt.3301039
    • A. Bragonzi, A. Boletta, A. Biffi, A. Muggia, G. Sersale, S.H. Cheng, C. Bordignon, B.M. Assael, M. Conese, Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs, Gene Ther. 6 (1999) 1995-2004. (Pubitemid 30076870)
    • (1999) Gene Therapy , vol.6 , Issue.12 , pp. 1995-2004
    • Bragonzi, A.1    Boletta, A.2    Biffi, A.3    Muggia, A.4    Sersale, G.5    Cheng, S.H.6    Bordignon, C.7    Assael, B.M.8    Conese, M.9
  • 12
    • 0035408714 scopus 로고    scopus 로고
    • Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo
    • DOI 10.1002/jgm.187
    • L. Wightman, R. Kircheis, V. Rössler, S. Carotta, R. Ruzicka, M. Kursa, E. Wagner, Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo, J. Gene Med. 3 (2001) 362-372. (Pubitemid 33691776)
    • (2001) Journal of Gene Medicine , vol.3 , Issue.4 , pp. 362-372
    • Wightman, L.1    Kircheis, R.2    Rossler, V.3    Garotta, S.4    Ruzicka, R.5    Kursa, M.6    Wagner, E.7
  • 13
    • 33646814034 scopus 로고    scopus 로고
    • Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice
    • DOI 10.1124/jpet.105.100669
    • S. Kawakami, Y. Ito, P. Charoensit, F. Yamashita, M. Hashida, Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice, J. Pharmacol. Exp. Ther. 317 (2006) 1382-1390. (Pubitemid 43764145)
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.317 , Issue.3 , pp. 1382-1390
    • Kawakami, S.1    Ito, Y.2    Charoensit, P.3    Yamashita, F.4    Hashida, M.5
  • 14
    • 33750932907 scopus 로고    scopus 로고
    • Structural advantage of dendritic poly(l-lysine) for gene delivery into cells
    • DOI 10.1016/j.bmc.2006.09.033, PII S0968089606007644
    • M. Yamagata, T. Kawano, K. Shiba, T. Mori, Y. Katayama, T. Niidome, Structural advantage of dendritic poly(L-lysine) for gene delivery into cells, Bioorg. Med. Chem. 15 (2007) 526-532. (Pubitemid 44738554)
    • (2007) Bioorganic and Medicinal Chemistry , vol.15 , Issue.1 , pp. 526-532
    • Yamagata, M.1    Kawano, T.2    Shiba, K.3    Mori, T.4    Katayama, Y.5    Niidome, T.6
  • 15
    • 0037130553 scopus 로고    scopus 로고
    • Structure-activity relationships of poly(L-lysines): Effects of pegylation and molecular shape on physicochemical and biological properties in gene delivery
    • DOI 10.1016/S0168-3659(02)00178-5, PII S0168365902001785
    • M. Männistö, S. Vanderkerken, V. Toncheva, M. Elomaa, M. Ruponen, E. Schacht, A. Urtti, Structure-activity relationships of poly(L-lysines): effects of pegylation and molecular shape on physicochemical and biological properties in gene delivery, J. Control. Release 83 (2002) 169-182. (Pubitemid 35239824)
    • (2002) Journal of Controlled Release , vol.83 , Issue.1 , pp. 169-182
    • Mannisto, M.1    Vanderkerken, S.2    Toncheva, V.3    Elomaa, M.4    Ruponen, M.5    Schacht, E.6    Urtti, A.7
  • 17
    • 0032892476 scopus 로고    scopus 로고
    • Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle
    • DOI 10.1002/(SICI)1097-4636(1999 0605)45:3<268::AID-JBM15>3 .0.CO;2-Q
    • W.T. Godbey, K.K. Wu, A.G. Mikos, Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle, J. Biomed. Mater. Res. 45 (1999) 268-275. (Pubitemid 29165943)
    • (1999) Journal of Biomedical Materials Research , vol.45 , Issue.3 , pp. 268-275
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 18
    • 23944439174 scopus 로고    scopus 로고
    • Transfection efficiency of chitosan vectors: Effect of polymer molecular weight and degree of deacetylation
    • DOI 10.1016/j.jconrel.2005.05.004, PII S0168365905002324
    • M. Huang, C.-W. Fong, E. Khor, L.-Y. Lim, Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation, J. Control. Release 106 (2005) 391-406. (Pubitemid 41187448)
    • (2005) Journal of Controlled Release , vol.106 , Issue.3 , pp. 391-406
    • Huang, M.1    Fong, C.-W.2    Khor, E.3    Lim, L.-Y.4
  • 19
    • 84861780764 scopus 로고    scopus 로고
    • Hyperbranched polylysine: A versatile, biodegradable transfection agent for the production of recombinant proteins by transient gene expression and the trans-fection of primary cells
    • Z. Kadlecova, Y. Rajendra, M. Matasci, D. Hacker, L. Baldi, F.M. Wurm, H.-A. Klok, Hyperbranched polylysine: a versatile, biodegradable transfection agent for the production of recombinant proteins by transient gene expression and the trans-fection of primary cells, Macromol. Biosci. 12 (2012) 794-804.
    • (2012) Macromol. Biosci. , vol.12 , pp. 794-804
    • Kadlecova, Z.1    Rajendra, Y.2    Matasci, M.3    Hacker, D.4    Baldi, L.5    Wurm, F.M.6    Klok, H.-A.7
  • 20
    • 84860613890 scopus 로고    scopus 로고
    • Poly(ethyleneimine)-mediated large-scale transient gene expression: Influence of molecular weight, polydispersity and N-propionyl groups
    • Z. Kadlecova, S. Nallet, D.L. Hacker, L. Baldi, H.-A. Klok, F.M. Wurm, Poly(ethyleneimine)-mediated large-scale transient gene expression: influence of molecular weight, polydispersity and N-propionyl groups, Macromol. Biosci. 12 (2012) 628-636.
    • (2012) Macromol. Biosci. , vol.12 , pp. 628-636
    • Kadlecova, Z.1    Nallet, S.2    Hacker, D.L.3    Baldi, L.4    Klok, H.-A.5    Wurm, F.M.6
  • 21
    • 36549067268 scopus 로고    scopus 로고
    • The thermal polymerization of amino acids revisited; Synthesis and structural characterization of hyperbranched polymers from L-lysine
    • DOI 10.1002/pola.22295
    • M. Scholl, T.Q. Nguyen, B. Bruchmann, H.-A. Klok, The thermal polymerization of amino acids revisited; synthesis and structural characterization of hyperbranched polymers from L-lysine, J. Polym. Sci. A Polym. Chem. 45 (2007) 5494-5508. (Pubitemid 350190729)
    • (2007) Journal of Polymer Science, Part A: Polymer Chemistry , vol.45 , Issue.23 , pp. 5494-5508
    • Scholl, M.1    Nguyen, T.Q.2    Bruchmann, B.3    Klok, H.-A.4
  • 22
    • 26444612689 scopus 로고    scopus 로고
    • Large-scale transient transfection of mammalian cells: A newly emerging attractive option for recombinant protein production
    • DOI 10.1007/s10969-005-2826-4
    • S. Geisse, M. Henke, Large-scale transient transfection of mammalian cells: a newly emerging attractive option for recombinant protein production, J. Struct. Func. Genom. 6 (2005) 165-170. (Pubitemid 41428125)
    • (2005) Journal of Structural and Functional Genomics , vol.6 , Issue.2-3 , pp. 165-170
    • Geisse, S.1    Henke, M.2
  • 24
    • 8344271026 scopus 로고    scopus 로고
    • Production of recombinant protein therapeutics in cultivated mammalian cells
    • DOI 10.1038/nbt1026
    • F.M. Wurm, Production of recombinant protein therapeutics in cultivated mammalian cells, Nat. Biotechnol. 22 (2004) 1393-1398. (Pubitemid 39482858)
    • (2004) Nature Biotechnology , vol.22 , Issue.11 , pp. 1393-1398
    • Wurm, F.M.1
  • 25
    • 84867458431 scopus 로고    scopus 로고
    • A comparative study on the in vitro cytotoxicity of linear, dendritic and hyperbranched polylysine analogs
    • Z. Kadlecova, L. Baldi, D. Hacker, F.M. Wurm, H.-A. Klok, A comparative study on the in vitro cytotoxicity of linear, dendritic and hyperbranched polylysine analogs, Biomacromolecules 13 (2012) 3127-3137.
    • (2012) Biomacromolecules , vol.13 , pp. 3127-3137
    • Kadlecova, Z.1    Baldi, L.2    Hacker, D.3    Wurm, F.M.4    Klok, H.-A.5
  • 26
    • 34548009347 scopus 로고    scopus 로고
    • Controlling polymer architecture in the thermal hyperbranched polymerization of L-lysine
    • DOI 10.1021/ma070494l
    • M. Scholl, T.Q. Nguyen, B. Bruchmann, H.-A. Klok, Controlling polymer architecture in the thermal hyperbranched polymerization of L-lysine, Macromolecules 40 (2007) 5726-5734. (Pubitemid 47280846)
    • (2007) Macromolecules , vol.40 , Issue.16 , pp. 5726-5734
    • Scholl, M.1    Nguyen, T.Q.2    Bruchmann, B.3    Klok, H.-A.4
  • 27
    • 0020574233 scopus 로고
    • Deletion of the diploid dihydrofolate reductase locus from cultured mammalian cells
    • G. Urlaub, E. Käs, A.M. Carothers, L.A. Chasin, Deletion of the diploid dihydrofolate reductase locus from cultured mammalian cells, Cell 33 (1983) 405-412. (Pubitemid 13062492)
    • (1983) Cell , vol.33 , Issue.2 , pp. 405-412
    • Urlaub, G.1    Kas, E.2    Carothers, A.M.3    Chasin, L.A.4
  • 28
    • 14244252530 scopus 로고    scopus 로고
    • Orbital shaker technology for the cultivation of mammalian cells in suspension
    • DOI 10.1002/bit.20358
    • N. Muller, P. Girard, D.L. Hacker, M. Jordan, F.M. Wurm, Orbital shaker technology for the cultivation of mammalian cells in suspension, Biotechnol. Bioeng. 89 (2005) 400-406. (Pubitemid 40288900)
    • (2005) Biotechnology and Bioengineering , vol.89 , Issue.4 , pp. 400-406
    • Muller, N.1    Girard, P.2    Hacker, D.L.3    Jordan, M.4    Wurm, F.M.5
  • 29
    • 79960470348 scopus 로고    scopus 로고
    • The PiggyBac transposon enhances the frequency of CHO stable cell line generation and yields recombinant lines with superior productivity and stability
    • M. Matasci, L. Baldi, D.L. Hacker, F.M. Wurm, The PiggyBac transposon enhances the frequency of CHO stable cell line generation and yields recombinant lines with superior productivity and stability, Biotechnol. Bioeng. 108 (2011) 2141-2150.
    • (2011) Biotechnol. Bioeng. , vol.108 , pp. 2141-2150
    • Matasci, M.1    Baldi, L.2    Hacker, D.L.3    Wurm, F.M.4
  • 30
    • 0035922883 scopus 로고    scopus 로고
    • Transient gene expression: Recombinant protein production with suspension-adapted HEK293-EBNA cells
    • DOI 10.1002/bit.1179
    • P. Meissner, H. Pick, A. Kulangara, P. Chatellard, K. Friedrich, F.M. Wurm, Transient gene expression: recombinant protein production with suspension-adapted HEK293-EBNA cells, Biotechnol. Bioeng. 75 (2001) 197-203. (Pubitemid 32937290)
    • (2001) Biotechnology and Bioengineering , vol.75 , Issue.2 , pp. 197-203
    • Meissner, P.1    Pick, H.2    Kulangara, A.3    Chatellard, P.4    Friedrich, K.5    Wurm, F.M.6
  • 31
    • 34548140121 scopus 로고    scopus 로고
    • Cytoskeletal involvement in the cellular trafficking of plasmid/PEI derivative complexes
    • DOI 10.1016/j.jconrel.2007.06.015, PII S0168365907002994
    • S. Grosse, Y. Aron, G. Thevenot, M. Monsigny, I. Fajac, Cytoskeletal involvement in the cellular trafficking of plasmid/PEI derivative complexes, J. Control. Release 122 (2007) 111-117. (Pubitemid 47299144)
    • (2007) Journal of Controlled Release , vol.122 , Issue.1 , pp. 111-117
    • Grosse, S.1    Aron, Y.2    Thevenot, G.3    Monsigny, M.4    Fajac, I.5
  • 32
    • 0035176318 scopus 로고    scopus 로고
    • Microtubule involvement in the intracellular dynamics for gene trasnfection mediated by cationic liposomes
    • DOI 10.1038/sj.gt.3301573
    • S. Hasegawa, N. Hirashima, M. Nakanishi, Microtubule involvement in the intra-cellular dynamics for gene transfection mediated by cationic liposomes, Gene Ther. 8 (2001) 1669-1673. (Pubitemid 33085589)
    • (2001) Gene Therapy , vol.8 , Issue.21 , pp. 1669-1673
    • Hasegawa, S.1    Hirashima, N.2    Nakanishi, M.3
  • 33
    • 0042199010 scopus 로고    scopus 로고
    • Cell surface adherence and endocytosis of protein transduction domains
    • DOI 10.1016/S1525-0016(03)00135-7
    • M. Lundberg, S. Wikstrom, M. Johansson, Cell surface adherence and endocytosis of protein transduction domains, Mol. Ther. 8 (2003) 143-150. (Pubitemid 36939305)
    • (2003) Molecular Therapy , vol.8 , Issue.1 , pp. 143-150
    • Lundberg, M.1    Wikstrom, S.2    Johansson, M.3
  • 34
    • 79953839673 scopus 로고    scopus 로고
    • Revisit complexation between DNA and polyethyleneimine - Effect of uncomplexed chains free in the solution mixture on gene transfection
    • Y. Yue, F. Jin, R. Deng, J. Cai, Y. Chen, M.C.M. Lin, H.-F. Kung, C. Wu, Revisit complexation between DNA and polyethyleneimine - effect of uncomplexed chains free in the solution mixture on gene transfection, J. Control. Release 155 (2011) 67-76.
    • (2011) J. Control. Release , vol.155 , pp. 67-76
    • Yue, Y.1    Jin, F.2    Deng, R.3    Cai, J.4    Chen, Y.5    Lin, M.C.M.6    Kung, H.-F.7    Wu, C.8
  • 35
    • 0030042764 scopus 로고    scopus 로고
    • Actin filaments facilitate two steps of endocytosis
    • A. Durrbach, D. Louvard, E. Coudrier, Actin filaments facilitate two steps of endocytosis, J. Cell Sci. 109 (1996) 457-465. (Pubitemid 26057126)
    • (1996) Journal of Cell Science , vol.109 , Issue.2 , pp. 457-465
    • Durrbach, A.1    Louvard, D.2    Coudrier, E.3
  • 36
    • 24144442691 scopus 로고    scopus 로고
    • Rab conversion as a mechanism of progression from early to late endosomes
    • DOI 10.1016/j.cell.2005.06.043, PII S0092867405006975
    • J. Rink, E. Ghigo, Y. Kalaidzidis, M. Zerial, Rab conversion as a mechanism of progression from early to late endosomes, Cell 122 (2005) 735-749. (Pubitemid 41242638)
    • (2005) Cell , vol.122 , Issue.5 , pp. 735-749
    • Rink, J.1    Ghigo, E.2    Kalaidzidis, Y.3    Zerial, M.4
  • 37
    • 0030920202 scopus 로고    scopus 로고
    • Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro
    • R.J. Vasquez, B. Howell, A.M.C. Yvon, P. Wadsworth, L. Cassimeris, Nanomolar concentrations of nocodazole can alter microtubule dynamic instability in vivo and in vitro, Mol. Biol. Cell 8 (1997) 973-985. (Pubitemid 27276319)
    • (1997) Molecular Biology of the Cell , vol.8 , Issue.6 , pp. 973-985
    • Vasquez, R.J.1    Howell, B.2    Yvon, A.-M.C.3    Wadsworth, P.4    Cassimeris, L.5
  • 39
    • 24344449035 scopus 로고    scopus 로고
    • Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins
    • DOI 10.1091/mbc.E05-03-0213
    • K. Janvier, J.S. Bonifacino, Role of endocytic machinery in the sorting of lysosome-associated membrane proteins, Mol. Biol. Cell 16 (2005) 4231-4242. (Pubitemid 41262892)
    • (2005) Molecular Biology of the Cell , vol.16 , Issue.9 , pp. 4231-4242
    • Janvier, K.1    Bonifacino, J.S.2
  • 40
    • 0011913143 scopus 로고
    • Bafilomycins - A class of inhibitors of membrane ATPases from microorganisms, animal-cells and plant-cells
    • E.J. Bowman, A. Siebers, K. Altendorf, Bafilomycins - a class of inhibitors of membrane ATPases from microorganisms, animal-cells and plant-cells, Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 7972-7976.
    • (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , pp. 7972-7976
    • Bowman, E.J.1    Siebers, A.2    Altendorf, K.3
  • 41
    • 0028340169 scopus 로고
    • + channel of vacuolar proton pumps
    • B.P. Crider, X.S. Xie, D.K. Stone, Bafilomycin inhibits proton flow through the H+ channel of vacuolar proton pumps, J. Biol. Chem. 269 (1994) 17379-17381. (Pubitemid 24218007)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.26 , pp. 17379-17381
    • Crider, B.P.1    Xie, X.-S.2    Stone, D.K.3
  • 42
    • 0028014372 scopus 로고
    • Vacuolar ATPase activity is required for endosomal carrier vesicle formation
    • M.J. Clague, S. Urbe, F. Aniento, J. Gruenberg, Vacuolar ATPase activity is requred for endosomal carrier vesicle formation, J. Biol. Chem. 269 (1994) 21-24. (Pubitemid 24026612)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.1 , pp. 21-24
    • Clague, M.J.1    Urbe, S.2    Aniento, F.3    Gruenberg, J.4
  • 43
    • 0025313130 scopus 로고
    • Transferrin polycation-mediated introduction of DNA into human leukemic cells: Stimulation by agents that affect the survival of trasfected DNA or modulate transferrin receptor levels
    • M. Cotton, F. Langlerouault, H. Kirlappos, E. Wagner, K. Mechtler, M. Zenke, H. Beug, M.L. Birnstiel, Transferrin polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of trasfected DNA or modulate transferrin receptor levels, Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 4033-4037.
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 4033-4037
    • Cotton, M.1    Langlerouault, F.2    Kirlappos, H.3    Wagner, E.4    Mechtler, K.5    Zenke, M.6    Beug, H.7    Birnstiel, M.L.8
  • 44
    • 0029318090 scopus 로고
    • Delivery of DNA into Mammalian cells by receptor-mediated endocytosis and gene therapy
    • J. Guy, D. Brabek, M. Antoniou, Delivery of DNA into mammalian cells by receptor-mediated endocytosis and gene therapy, Mol. Biotechnol. 3 (1995) 237-248.
    • (1995) Mol. Biotechnol. , vol.3 , pp. 237-248
    • Guy, J.1    Brabek, D.2    Antoniou, M.3
  • 45
    • 0029979929 scopus 로고    scopus 로고
    • Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes
    • DOI 10.1006/excr.1996.0169
    • P. Erbacher, A.C. Roche, M. Monsigny, P. Midoux, Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA lactosylated polylysine complexes, Exp. Cell Res. 225 (1996) 186-194. (Pubitemid 26158468)
    • (1996) Experimental Cell Research , vol.225 , Issue.1 , pp. 186-194
    • Erbacher, P.1    Roche, A.C.2    Monsigny, M.3    Midoux, P.4
  • 46
    • 0002656438 scopus 로고    scopus 로고
    • Polyethylene glycol-grafted poly-L-lysine as polymeric gene carder
    • DOI 10.1016/S0168-3659(97)00174-0, PII S0168365997001740
    • Y.H. Choi, F. Liu, J.S. Kim, Y.K. Choi, J.S. Park, S.W. Kim, Polyethylene glycol-grafted poly-L-lysine as polymeric gene carrier, J. Control. Release 54 (1998) 39-48. (Pubitemid 28255236)
    • (1998) Journal of Controlled Release , vol.54 , Issue.1 , pp. 39-48
    • Choi, Y.H.1    Liu, F.2    Kim, J.-S.3    Choi, Y.K.4    Park, J.S.5    Kim, S.W.6
  • 49
    • 19744372388 scopus 로고    scopus 로고
    • Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis
    • DOI 10.1002/jgm.696
    • A. Akinc, M. Thomas, A.M. Klibanov, R. Langer, Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis, J. Gene Med. 7 (2005) 657-663. (Pubitemid 40744532)
    • (2005) Journal of Gene Medicine , vol.7 , Issue.5 , pp. 657-663
    • Akinc, A.1    Thomas, M.2    Klibanov, A.M.3    Langer, R.4


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