Biodistribution and tissue expression kinetics of plasmid DNA complexed with polyethylenimines of different molecular weight and structure

Journal of Controlled Release

Volumn 118, Issue 1, 2007, Pages 118-125

  Jeong, Gil Jae ^a   Byun, Hyang Min ^b   Kim, Jung Mogg ^c   Yoon, Ho ^b   Choi, Han Gon ^d   Kim, Won Ki ^e   Kim, Sun Jae ^f   Oh, Yu Kyoung ^a  

^a Korea University   (South Korea)

^b CHA University   (South Korea)

^c Hanyang University   (South Korea)

^d Yeungnam University   (South Korea)

^e Ewha Womans University   (South Korea)

^f Sejong University   (South Korea)

Author keywords

Biodistribution; Low molecular weight; Nonviral gene delivery; Polyethylenimine; Safety

Indexed keywords

BIOLOGICAL ORGANS; COMPLEXATION; HISTOLOGY; MOLECULAR WEIGHT; NITROGEN COMPOUNDS; TISSUE;

BIODISTRIBUTION; NONVIRAL GENE DELIVERY; POLYETHYLENIMINES; PROINFLAMMATORY CHEMOKINE RECEPTORS;

DNA;

CHEMOKINE RECEPTOR; INTERLEUKIN 2; MESSENGER RNA; PLASMID DNA; POLYETHYLENEIMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; FEMALE; GENE EXPRESSION; GENE TARGETING; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; DNA; FEMALE; GENE TRANSFER TECHNIQUES; INJECTIONS, INTRAVENOUS; KIDNEY; LUNG; MALE; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; POLYETHYLENEIMINE; RECEPTORS, CHEMOKINE; RNA, MESSENGER; SPLEEN; TISSUE DISTRIBUTION;

EID: 33847120795     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.12.009     Document Type: Article

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