Therapeutic targeting of chitosan-PEG-folate-complexed oncolytic adenovirus for active and systemic cancer gene therapy

Journal of Controlled Release

Volumn 169, Issue 3, 2013, Pages 257-265

  Kwon, Oh Joon ^a   Kang, Eunah ^a   Choi, Joung Woo ^b   Kim, Sung Wan ^a,c   Yun, Chae Ok ^a,c  

^a Hanyang University   (South Korea)

^b Yonsei University   (South Korea)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

Chitosan; Folate; Oncolytic adenovirus; Poly(ethylene glycol)

Indexed keywords

AMINO ACIDS; BLOOD; CARDIOVASCULAR SYSTEM; CHITIN; CHITOSAN; CONJUGATED POLYMERS; CROSSLINKING; DISEASES; HISTOLOGY; MAMMALS; PHYSIOLOGY; POLYETHYLENE GLYCOLS; POLYMERASE CHAIN REACTION; TISSUE; TUMORS;

ANTI-TUMOR EFFICACY; BIOLUMINESCENCE IMAGING; FOLATE; NEUTRALIZING ANTIBODIES; ONCOLYTIC ADENOVIRUS; QUANTITATIVE POLYMERASE CHAIN REACTION; SYSTEMIC ADMINISTRATION; THERAPEUTIC EFFICACY;

GENE THERAPY;

ADENOVIRUS VECTOR; CHITOSAN; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; FOLATE RECEPTOR; FOLIC ACID; MACROGOL; NEUTRALIZING ANTIBODY; ONCOLYTIC ADENOVIRUS; TELOMERASE REVERSE TRANSCRIPTASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLUMINESCENCE; CANCER CELL; CANCER GENE THERAPY; CANCER INHIBITION; CARCINOMA; CELL KILLING; CELL STRAIN HEK293; CELL STRAIN KB; CIRCULATION TIME; CROSS LINKING; DRUG CLEARANCE; DRUG EFFICACY; DRUG SAFETY; DRUG SELECTIVITY; FEMALE; GENE CONTROL; GENE TARGETING; GLYCOSYLATION; HELA CELL; HUMAN; HUMAN CELL; HYPOXIA; IMMUNE RESPONSE; IMMUNOGENICITY; KIDNEY CELL; LIVER; LIVER INJURY; MOUSE; NONHUMAN; PLASMA CLEARANCE; POLYMERASE CHAIN REACTION; PRIMARY TUMOR; PRIORITY JOURNAL; PROMOTER REGION; SYSTEMIC THERAPY; VIRUS REPLICATION;

EID: 84885171866     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.03.030     Document Type: Article

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