Erythropoietin gene delivery using an arginine-grafted bioreducible polymer system

Journal of Controlled Release

Volumn 157, Issue 3, 2012, Pages 437-444

  Nam, Hye Yeong ^a   Lee, Youngsook ^a   Lee, Minhyung ^b   Shin, Sug Kyun ^c   Kim, Tae Il ^d   Kim, Sung Wan ^a,b   Bull, David A ^e  

^a UNIVERSITY OF UTAH   (United States)

^b Hanyang University   (South Korea)

^c Ilsan Hospital   (South Korea)

^d Seoul National University   (South Korea)

^e UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Bioreducible polymer; Erythropoietin; Gene therapy; Hemolysis; PEG

Indexed keywords

BIOREDUCIBLE POLYMER; CELL COLONIES; CELL TYPES; CHARGED PROTEINS; CONTROLLED RELEASE; DISEASE STATE; ERYTHROPOIETIN; EXPRESSION EFFICIENCY; GENE DELIVERY; GENE DELIVERY SYSTEMS; HEMATOPOIETIC PROGENITOR CELLS; HEMOLYSIS; IN-VITRO; ISCHEMIC INJURIES; PARTICLE AGGREGATION; POLYMERIC CARRIERS; POLYPLEXES; RED BLOOD CELL; THERAPEUTIC AGENTS; THERAPEUTIC APPLICATION; THERAPEUTIC MODALITY;

ARGININE; BLOOD; CYTOLOGY; ENDOTHELIAL CELLS; GENE THERAPY; GENE TRANSFER; GRAFTING (CHEMICAL); MOLECULAR BIOLOGY; POLYETHYLENE GLYCOLS;

FUNCTIONAL POLYMERS;

ARGININE; ARGININE GRAFTED BIOREDUCIBLE POLYMER; ERYTHROPOIETIN; MACROGOL; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; ARGININE; CELL LINE; CELL SURVIVAL; DNA; DRUG CARRIERS; ERYTHROCYTES; ERYTHROPOIETIN; HEMOLYSIS; LEUKOCYTES, MONONUCLEAR; NANOPARTICLES; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION;

EID: 84857357510     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.10.014     Document Type: Article

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