The effect of sequestration by nontarget tissues on anti-tumor efficacy of systemically applied, conditionally replicating adenovirus vectors

Molecular Therapy

Volumn 8, Issue 5, 2003, Pages 746-755

  Bernt, Kathrin M ^a   Ni, Shaoheng ^a   Li, Zong Yi ^a   Shayakhmetov, Dmitry M ^a   Lieber, André ^a,b  

^a Division of Medical Genetics   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Adenovirus; Capsid modification; Targeting; Tumor gene therapy

Indexed keywords

ADENOVIRUS VECTOR; DNA;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARCINOMA CELL; CELL TRANSFER; CONTROLLED STUDY; CYTOLYSIS; DISEASE MODEL; DNA REPLICATION; DRUG DISTRIBUTION; GENE THERAPY; GENETIC TRANSDUCTION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER METASTASIS; LIVER SINUSOID; LIVER TOXICITY; MOUSE; NONHUMAN; SAFETY; UTERINE CERVIX CARCINOMA; VIRAL GENE DELIVERY SYSTEM; VIRUS PARTICLE; VIRUS REPLICATION;

ADENOVIRIDAE; ANIMALIA;

EID: 0346242736     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2003.07.006     Document Type: Article

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