Untangling structure-function relationships in the rhomboid family of intramembrane proteases

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 12, 2013, Pages 2862-2872

  Brooks, Cory L ^a   Lemieux, M Joanne ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

GlpG; Intramembrane protease; Membrane protein structure; Rhomboid protease; Serine protease; X ray crystallography

Indexed keywords

BACTERIAL ENZYME; GLPG PROTEIN; MEMBRANE PROTEIN; RHOMBOID PROTEIN; SERINE PROTEINASE; UNCLASSIFIED DRUG;

BIOPHYSICS; CATALYSIS; CLINICAL RESEARCH; CRYSTAL STRUCTURE; CYTOSOL; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; EUKARYOTE; HAEMOPHILUS INFLUENZAE; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROKARYOTE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

GLPG; INTRAMEMBRANE PROTEASE; MEMBRANE PROTEIN STRUCTURE; RHOMBOID PROTEASE; SERINE PROTEASE; X-RAY CRYSTALLOGRAPHY;

BINDING SITES; BIOCATALYSIS; CATALYTIC DOMAIN; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; ENDOPEPTIDASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HAEMOPHILUS INFLUENZAE; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; SERINE PROTEINASE INHIBITORS; SUBSTRATE SPECIFICITY;

EID: 84885161299     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2013.05.003     Document Type: Review

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