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Volumn 73, Issue 19, 2013, Pages 6056-6067

FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function

Author keywords

[No Author keywords available]

Indexed keywords

AFIMOXIFENE; HISTONE DEACETYLASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO; VORINOSTAT;

EID: 84885049450     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0453     Document Type: Article
Times cited : (46)

References (44)
  • 1
    • 33745906528 scopus 로고    scopus 로고
    • Retinoblastoma tumor suppressor: Where cancer meets the cell cycle
    • Knudsen ES, Knudsen KE. Retinoblastoma tumor suppressor: where cancer meets the cell cycle. Exp Biol Med 2006;231:1271-81.
    • (2006) Exp Biol Med , vol.231 , pp. 1271-1281
    • Knudsen, E.S.1    Knudsen, K.E.2
  • 2
    • 0037010122 scopus 로고    scopus 로고
    • E2F1 pathways to apoptosis
    • Ginsberg D. E2F1 pathways to apoptosis. FEBS Lett 2002;529:122-5.
    • (2002) FEBS Lett , vol.529 , pp. 122-125
    • Ginsberg, D.1
  • 3
    • 0028960617 scopus 로고
    • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
    • Kowalik TF, DeGregori J, Schwarz JK, Nevins JR. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J Virol 1995;69:2491-500.
    • (1995) J Virol , vol.69 , pp. 2491-2500
    • Kowalik, T.F.1    DeGregori, J.2    Schwarz, J.K.3    Nevins, J.R.4
  • 5
    • 0035878122 scopus 로고    scopus 로고
    • Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
    • Lin WC, Lin FT, Nevins JR. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev 2001;15:1833-44.
    • (2001) Genes Dev , vol.15 , pp. 1833-1844
    • Lin, W.C.1    Lin, F.T.2    Nevins, J.R.3
  • 6
  • 9
    • 1542305653 scopus 로고    scopus 로고
    • Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis
    • Hershko T, Ginsberg D. Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis. J Biol Chem 2004;279:8627-34.
    • (2004) J Biol Chem , vol.279 , pp. 8627-8634
    • Hershko, T.1    Ginsberg, D.2
  • 11
    • 0141814666 scopus 로고    scopus 로고
    • Specificity in the activation and control of transcription factor E2F-dependent apoptosis
    • Hallstrom TC, Nevins JR. Specificity in the activation and control of transcription factor E2F-dependent apoptosis. Proc Natl Acad Sci U S A 2003;100:10848-53.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10848-10853
    • Hallstrom, T.C.1    Nevins, J.R.2
  • 12
    • 37349070024 scopus 로고    scopus 로고
    • An E2F1-dependent gene expression program that determines the balance between proliferation and cell death
    • Hallstrom TC, Mori S, Nevins JR. An E2F1-dependent gene expression program that determines the balance between proliferation and cell death. Cancer Cell 2008;13:11-22.
    • (2008) Cancer Cell , vol.13 , pp. 11-22
    • Hallstrom, T.C.1    Mori, S.2    Nevins, J.R.3
  • 13
    • 34249281690 scopus 로고    scopus 로고
    • Stressing the role of FoxO proteins in lifespan and disease
    • van der Horst A, Burgering BM. Stressing the role of FoxO proteins in lifespan and disease. Nat Rev Mol Cell Biol 2007;8:440-50.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 440-450
    • Van Der Horst, A.1    Burgering, B.M.2
  • 14
    • 0035135841 scopus 로고    scopus 로고
    • Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
    • Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol 2001;21:952-65.
    • (2001) Mol Cell Biol , vol.21 , pp. 952-965
    • Brunet, A.1    Park, J.2    Tran, H.3    Hu, L.S.4    Hemmings, B.A.5    Greenberg, M.E.6
  • 15
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999;96:857-68.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3    Lin, M.Z.4    Juo, P.5    Hu, L.S.6
  • 16
    • 2942726155 scopus 로고    scopus 로고
    • The ins and outs of FoxO shuttling: Mechanisms of FoxO translocation and transcriptional regulation
    • Van der Heide LP, Hoekman MF, Smidt MP. The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation. Biochem J 2004;380:297-309.
    • (2004) Biochem J , vol.380 , pp. 297-309
    • Van Der Heide, L.P.1    Hoekman, M.F.2    Smidt, M.P.3
  • 19
  • 20
    • 84869116884 scopus 로고    scopus 로고
    • A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes
    • Glasmacher E, Agrawal S, Chang AB, Murphy TL, Zeng W, Vander Lugt B, et al. A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science 2012;338:975-80.
    • (2012) Science , vol.338 , pp. 975-980
    • Glasmacher, E.1    Agrawal, S.2    Chang, A.B.3    Murphy, T.L.4    Zeng, W.5    Vander Lugt, B.6
  • 21
    • 34249079154 scopus 로고    scopus 로고
    • Network motifs: Theory and experimental approaches
    • Alon U. Network motifs: theory and experimental approaches. Nat Rev Genet 2007;8:450-61.
    • (2007) Nat Rev Genet , vol.8 , pp. 450-461
    • Alon, U.1
  • 22
    • 0035252592 scopus 로고    scopus 로고
    • E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis
    • Muller H, Bracken AP, Vernell R, Moroni MC, Christians F, Grassilli E, et al. E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev 2001;15:267-85.
    • (2001) Genes Dev , vol.15 , pp. 267-285
    • Muller, H.1    Bracken, A.P.2    Vernell, R.3    Moroni, M.C.4    Christians, F.5    Grassilli, E.6
  • 25
    • 33846295218 scopus 로고    scopus 로고
    • FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
    • Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, et al. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 2007;128:309-23.
    • (2007) Cell , vol.128 , pp. 309-323
    • Paik, J.H.1    Kollipara, R.2    Chu, G.3    Ji, H.4    Xiao, Y.5    Ding, Z.6
  • 26
    • 0031438119 scopus 로고    scopus 로고
    • Ionizing radiation-inducible apoptosis in the absence of p53 linked to transcription factor EGR-1
    • Ahmed MM, Sells SF, Venkatasubbarao K, Fruitwala SM, Muthukkumar S, Harp C, et al. Ionizing radiation-inducible apoptosis in the absence of p53 linked to transcription factor EGR-1. J Biol Chem 1997;272:33056-61.
    • (1997) J Biol Chem , vol.272 , pp. 33056-33061
    • Ahmed, M.M.1    Sells, S.F.2    Venkatasubbarao, K.3    Fruitwala, S.M.4    Muthukkumar, S.5    Harp, C.6
  • 27
    • 33846552984 scopus 로고    scopus 로고
    • NAG-1 upregulation mediated by EGR-1 and p53 is critical for quercetin-induced apoptosis in HCT116 colon carcinoma cells
    • Lim JH, Park JW, Min DS, Chang JS, Lee YH, Park YB, et al. NAG-1 upregulation mediated by EGR-1 and p53 is critical for quercetin-induced apoptosis in HCT116 colon carcinoma cells. Apoptosis 2007;12:411-21.
    • (2007) Apoptosis , vol.12 , pp. 411-421
    • Lim, J.H.1    Park, J.W.2    Min, D.S.3    Chang, J.S.4    Lee, Y.H.5    Park, Y.B.6
  • 28
    • 0042068270 scopus 로고    scopus 로고
    • The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells
    • Pignatelli M, Luna-Medina R, Perez-Rendon A, Santos A, Perez-Castillo A. The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells. Biochem J 2003;373:739-46.
    • (2003) Biochem J , vol.373 , pp. 739-746
    • Pignatelli, M.1    Luna-Medina, R.2    Perez-Rendon, A.3    Santos, A.4    Perez-Castillo, A.5
  • 29
    • 79955707098 scopus 로고    scopus 로고
    • Egr-1 transactivates Bim gene expression to promote neuronal apoptosis
    • Xie B, Wang C, Zheng Z, Song B, Ma C, Thiel G, et al. Egr-1 transactivates Bim gene expression to promote neuronal apoptosis. J Neurosci 2011;31:5032-44.
    • (2011) J Neurosci , vol.31 , pp. 5032-5044
    • Xie, B.1    Wang, C.2    Zheng, Z.3    Song, B.4    Ma, C.5    Thiel, G.6
  • 30
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein, homologous to C. Elegans Ced-4, participates in cytochome c-dependent activation of caspase-3
    • Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein, homologous to C. elegans Ced-4, participates in cytochome c-dependent activation of caspase-3. Cell 1997;90:405-13.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 32
    • 21744443473 scopus 로고    scopus 로고
    • Ephrin signalling controls brain size by regulating apoptosis of neural progenitors
    • Depaepe V, Suarez-Gonzalez N, Dufour A, Passante L, Gorski JA, Jones KR, et al. Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Nature 2005;435:1244-50.
    • (2005) Nature , vol.435 , pp. 1244-1250
    • Depaepe, V.1    Suarez-Gonzalez, N.2    Dufour, A.3    Passante, L.4    Gorski, J.A.5    Jones, K.R.6
  • 33
    • 32944462834 scopus 로고    scopus 로고
    • Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
    • Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006;440:233-6.
    • (2006) Nature , vol.440 , pp. 233-236
    • Kanneganti, T.D.1    Ozoren, N.2    Body-Malapel, M.3    Amer, A.4    Park, J.H.5    Franchi, L.6
  • 34
    • 0029782494 scopus 로고    scopus 로고
    • Cathepsin D protease mediates programmed cell death induced by interferongamma, Fas/APO-1 and TNF-alpha
    • Deiss LP, Galinka H, Berissi H, Cohen O, Kimchi A. Cathepsin D protease mediates programmed cell death induced by interferongamma, Fas/APO-1 and TNF-alpha. EMBO J 1996;15:3861-70.
    • (1996) EMBO J , vol.15 , pp. 3861-3870
    • Deiss, L.P.1    Galinka, H.2    Berissi, H.3    Cohen, O.4    Kimchi, A.5
  • 35
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 37
    • 49149129916 scopus 로고    scopus 로고
    • Gene expression-based survival prediction in lung adenocarcinoma: A multi-site, blinded validation study
    • Shedden K, Taylor JM, Enkemann SA, Tsao MS, Yeatman TJ, Gerald WL, et al. Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med 2008;14:822-7.
    • (2008) Nat Med , vol.14 , pp. 822-827
    • Shedden, K.1    Taylor, J.M.2    Enkemann, S.A.3    Tsao, M.S.4    Yeatman, T.J.5    Gerald, W.L.6
  • 38
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
    • Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 2006;313:1929-35.
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1    Crawford, E.D.2    Peck, D.3    Modell, J.W.4    Blat, I.C.5    Wrobel, M.J.6
  • 40
    • 0036884829 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor in development and cancer
    • Classon M, Harlow E. The retinoblastoma tumour suppressor in development and cancer. Nat Rev Cancer 2002;2:910-7.
    • (2002) Nat Rev Cancer , vol.2 , pp. 910-917
    • Classon, M.1    Harlow, E.2
  • 41
    • 33750920705 scopus 로고    scopus 로고
    • Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
    • DeGregori J, Johnson DG. Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr Mol Med 2006;6:739-48.
    • (2006) Curr Mol Med , vol.6 , pp. 739-748
    • DeGregori, J.1    Johnson, D.G.2
  • 42
    • 0036839685 scopus 로고    scopus 로고
    • Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D
    • Schmidt M, Fernandez de Mattos S, van der Horst A, Klompmaker R, Kops GJ, Lam EW, et al. Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D. Mol Cel Biol 2002;22:7842-52.
    • (2002) Mol Cel Biol , vol.22 , pp. 7842-7852
    • Schmidt, M.1    De Mattos, F.S.2    Van Der Horst, A.3    Klompmaker, R.4    Kops, G.J.5    Lam, E.W.6
  • 43
    • 11144357466 scopus 로고    scopus 로고
    • IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
    • Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, Yang JY, et al. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 2004;117:225-37.
    • (2004) Cell , vol.117 , pp. 225-237
    • Hu, M.C.1    Lee, D.F.2    Xia, W.3    Golfman, L.S.4    Ou-Yang, F.5    Yang, J.Y.6
  • 44
    • 70349437076 scopus 로고    scopus 로고
    • P53 and E2f: Partners in life and death
    • Polager S, Ginsberg D. p53 and E2f: partners in life and death. Nat Rev Cancer 2009;9:738-48.
    • (2009) Nat Rev Cancer , vol.9 , pp. 738-748
    • Polager, S.1    Ginsberg, D.2


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