A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation

Lipids in Health and Disease

Volumn 12, Issue 1, 2013, Pages

  Bjørndal, Bodil ^a   Berge, Christ ^b   Ramsvik, Marie Sannes ^a   Svardal, Asbjørn ^a   Bohov, Pavol ^a   Skorve, Jon ^a   Berge, Rolf K ^a,b  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

Carnitine metabolism; High fat diet; Inflammation; Salmon protein; Tumor necrosis factor

Indexed keywords

ACETYLCARNITINE; ACYLCARNITINE; CARNITINE; CASEIN; FATTY ACID SYNTHASE; FISH PROTEIN; GAMMA BUTYROBETAINE; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PROTEIN HYDROLYSATE; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY ACID METABOLISM; GENE EXPRESSION; LIPID COMPOSITION; LIPID DIET; LIPID LIVER LEVEL; LIVER; MOUSE; NONHUMAN; TRANSGENE; WHITE ADIPOSE TISSUE;

ANIMALIA; MUS;

ADIPOSE TISSUE; ANIMALS; CARNITINE; CASEINS; CHRONIC DISEASE; DIET, HIGH-FAT; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FEMALE; FISH PROTEINS; FISHES; GENE EXPRESSION; HUMANS; INFLAMMATION; LIVER; MICE; MICE, TRANSGENIC; OVARY; PROTEOLYSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885012740     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-12-143     Document Type: Article

References (40)

1. Bioactive peptides and proteins from foods: indication for health effects. Moller NP, Scholz-Ahrens KE, Roos N, Schrezenmeir J, Eur J Nutr 2008 47 171 182 10.1007/s00394-008-0710-2 18506385
2. Isolation and identification of antihypertensive peptides from antarctic krill tail meat hydrolysate. Hatanaka A, Miyahara H, Suzuki KI, Sato S, J Food Sci 2009 74 116 H120 10.1111/j.1750-3841.2009.01138.x 19490329
3. Marine fish-derived bioactive peptides as potential antihypertensive agents. Kim SK, Ngo DH, Vo TS, Adv Food Nutr Res 2012 65 249 260 22361192
4. Purification of a novel angiotensin I-converting enzyme (ACE) inhibitory peptide with an antihypertensive effect from loach (Misgurnus anguillicaudatus). Li Y, Zhou J, Huang K, Sun Y, Zeng X, J Agric Food Chem 2012 60 1320 1325 10.1021/jf204118n 22224920
5. Free radical scavenging and angiotensin-I converting enzyme inhibitory peptides from Pacific cod (Gadus macrocephalus) skin gelatin. Ngo DH, Ryu B, Vo TS, Himaya SW, Wijesekara I, Kim SK, Int J Biol Macromol 2011 49 1110 1116 10.1016/j.ijbiomac.2011.09.009 21945677
6. In vitro and in vivo studies on the antioxidant activity of fish peptide isolated from the croaker (Otolithes ruber) muscle protein hydrolysate. Nazeer RA, Sampath Kumar NS, Jai Ganesh R, Peptides 2012 35 261 268 10.1016/j.peptides.2012.03.028 22504498
7. A review of fish-derived antioxidant and antimicrobial peptides: their production, assessment, and applications. Najafian L, Babji AS, Peptides 2012 33 178 185 10.1016/j.peptides.2011.11.013 22138166
8. Purification and identification of antioxidant peptides from the skin protein hydrolysate of two marine fishes, horse mackerel (Magalaspis cordyla) and croaker (Otolithes ruber). Sampath Kumar NS, Nazeer RA, Jaiganesh R, Amino Acids 2012 42 1641 1649 10.1007/s00726-011-0858-6 21384132
9. Antioxidant effect of a marine oligopeptide preparation from chum salmon (Oncorhynchus keta) by enzymatic hydrolysis in radiation injured mice. Yang R, Wang J, Liu Z, Pei X, Han X, Li Y, Mar Drugs 2011 9 2304 2315 10.3390/md9112304 22163188
10. Immunomodulating capacity of commercial fish protein hydrolysate for diet supplementation. Duarte J, Vinderola G, Ritz B, Perdigon G, Matar C, Immunobiology 2006 211 341 350 10.1016/j.imbio.2005.12.002 16716803
11. Reparative properties of a commercial fish protein hydrolysate preparation. Fitzgerald AJ, Rai PS, Marchbank T, Taylor GW, Ghosh S, Ritz BW, Playford RJ, Gut 2005 54 775 781 10.1136/gut.2004.060608 15888784
12. Clinical trial: protective effect of a commercial fish protein hydrolysate against indomethacin (NSAID)-induced small intestinal injury. Marchbank T, Limdi JK, Mahmood A, Elia G, Playford RJ, Aliment Pharmacol Ther 2008 28 799 804 10.1111/j.1365-2036.2008.03783.x 19145735
13. Hypolipidemic effect of dietary pea proteins: Impact on genes regulating hepatic lipid metabolism. Rigamonti E, Parolini C, Marchesi M, Diani E, Brambilla S, Sirtori CR, Chiesa G, Mol Nutr Food Res 2010 54 Suppl 1 24 S30 20077421
14. Relationship between amino acid composition of diet and plasma cholesterol level in growing rats fed a high cholesterol diet. Sugiyama K, Ohkawa S, Muramatsu K, J Nutr Sci Vitaminol (Tokyo) 1986 32 413 423 10.3177/jnsv.32.413 3806255
15. Dietary fish protein alters blood lipid concentrations and hepatic genes involved in cholesterol homeostasis in the rat model. Shukla A, Bettzieche A, Hirche F, Brandsch C, Stangl GI, Eder K, Br J Nutr 2006 96 674 682 17010226
16. Fish protein hydrolysate reduces plasma total cholesterol, increases the proportion of HDL cholesterol, and lowers acyl-CoA:cholesterol acyltransferase activity in liver of Zucker rats. Wergedahl H, Liaset B, Gudbrandsen OA, Lied E, Espe M, Muna Z, Mork S, Berge RK, J Nutr 2004 134 1320 1327 15173391
17. n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. Calder PC, Am J Clin Nutr 2006 83 1505S 1519S 16841861
18. Stearoyl CoA desaturase 1: role in cellular inflammation and stress. Liu X, Strable MS, Ntambi JM, Adv Nutr 2011 2 15 22 10.3945/an.110.000125 22211186
19. Stearoyl-CoA Desaturase 1 (SCD1) is a key factor mediating diabetes in MyD88-deficient mice. Yokoyama S, Hosoi T, Ozawa K, Gene 2012 497 340 343 10.1016/j.gene.2012.01.024 22326531
20. Effect of diet on linoleic acid desaturation and on some enzymes of carbohydrate metabolism. De Gomez Dumm IN, De Alaniz MJ, Brenner RR, J Lipid Res 1970 11 96 101 5418484
21. Regulatory function of delta6 desaturate-key enzyme of polyunsaturated fatty acid synthesis. Brenner RR, Adv Exp Med Biol 1977 83 85 101 10.1007/BF00802814 200115
22. Down-regulated expression of PPARalpha target genes, reduced fatty acid oxidation and altered fatty acid composition in the liver of mice transgenic for hTNFalpha. Glosli H, Gudbrandsen OA, Mullen AJ, Halvorsen B, Rost TH, Wergedahl H, Prydz H, Aukrust P, Berge RK, Biochim Biophys Acta 2005 1734 235 246 10.1016/j.bbalip.2005.02.011 15893958
23. Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance. Huang W, Metlakunta A, Dedousis N, Zhang P, Sipula I, Dube JJ, Scott DK, O'Doherty RM, Diabetes 2010 59 347 357 10.2337/db09-0016 19934001
24. PPARs, obesity and inflammation. Stienstra R, Duval C, Müller M, Kersten S, PPAR Res 2007 2007 95974 17389767
25. Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity. Stienstra R, Saudale F, Duval C, Keshtkar S, Groener JE, van Rooijen N, Staels B, Kersten S, Muller M, Hepatology 2010 51 511 522 10.1002/hep.23337 20054868
26. Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells. Kim MS, Sweeney TR, Shigenaga JK, Chui LG, Moser A, Grunfeld C, Feingold KR, Metabolism 2007 56 267 279 10.1016/j.metabol.2006.10.007 17224343
27. Carnitine revisited: potential use as adjunctive treatment in diabetes. Power RA, Hulver MW, Zhang JY, Dubois J, Marchand RM, Ilkayeva O, Muoio DM, Mynatt RL, Diabetologia 2007 50 824 832 10.1007/s00125-007-0605-4 17310372
28. Fish protein decreases serum cholesterol in rats by inhibition of cholesterol and bile acid absorption. Hosomi R, Fukunaga K, Arai H, Kanda S, Nishiyama T, Yoshida M, J Food Sci 2011 76 116 H121 10.1111/j.1750-3841.2011. 02130.x 22417359
29. Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome. Liaset B, Hao Q, Jorgensen H, Hallenborg P, Du ZY, Ma T, Marschall HU, Kruhoffer M, Li R, Li Q, et al. J Biol Chem 2011 286 28382 28395 10.1074/jbc.M111.234732 21680746
30. Fish protein hydrolysate elevates plasma bile acids and reduces visceral adipose tissue mass in rats. Liaset B, Madsen L, Hao Q, Criales G, Mellgren G, Marschall HU, Hallenborg P, Espe M, Froyland L, Kristiansen K, Biochim Biophys Acta 2009 1791 254 262 10.1016/j.bbalip.2009.01.016 19416649
31. Fatty acid desaturases in human adipose tissue: relationships between gene expression, desaturation indexes and insulin resistance. Sjogren P, Sierra-Johnson J, Gertow K, Rosell M, Vessby B, de Faire U, Hamsten A, Hellenius ML, Fisher RM, Diabetologia 2008 51 328 335 10.1007/s00125-007-0876-9 18030445
32. An extensive phenotypic characterization of the hTNFalpha transgenic mice. Hayward MD, Jones BK, Saparov A, Hain HS, Trillat AC, Bunzel MM, Corona A, Li-Wang B, Strenkowski B, Giordano C, et al. BMC Physiol 2007 7 13 10.1186/1472-6793-7-13 18070349
33. A rapid method of total lipid extraction and purification. Bligh EG, Dyer WJ, Can J Biochem Physiol 1959 37 911 917 10.1139/o59-099 13671378
34. Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. Chavali SR, Zhong WW, Utsunomiya T, Forse RA, Int Arch Allergy Immunol 1997 114 153 160 10.1159/000237661 9338609
35. Amino acid analysis utilizing phenylisothiocyanate derivatives. Cohen SA, Strydom DJ, Anal Biochem 1988 174 1 16 10.1016/0003-2697(88)90512-X 3064649
36. Enhancement of long-chain acyl-CoA hydrolase activity in peroxisomes and mitochondria of rat liver by peroxisomal proliferators. Berge RK, Flatmark T, Osmundsen H, Eur J Biochem 1984 141 637 644 10.1111/j.1432-1033.1984.tb08239.x 6146524
37. Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation. Madsen L, Froyland L, Dyroy E, Helland K, Berge RK, J Lipid Res 1998 39 583 593 9548590
38. On the mechanism of the hypolipidemic effect of sulfur-substituted hexadecanedioic acid (3-thiadicarboxylic acid) in normolipidemic rats. Skorve J, al-Shurbaji A, Asiedu D, Bjorkhem I, Berglund L, Berge RK, J Lipid Res 1993 34 1177 1185 8371065
39. Dietary supplementation of herring roe and milt enhances hepatic fatty acid catabolism in female mice transgenic for hTNFalpha. Bjorndal B, Burri L, Wergedahl H, Svardal A, Bohov P, Berge RK, Eur J Nutr 2011 51 741 753 21986673
40. Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks. Vigerust NF, Cacabelos D, Burri L, Berge K, Wergedahl H, Christensen B, Portero-Otin M, Viste A, Pamplona R, Berge RK, Bjørndal B, J Nutr Biochem 2011 23 1384 1393