-
1
-
-
0037832581
-
Recent insights into stearoyl-CoA desaturase-1
-
Ntambi JM,MiyazakiM. Recent insights into stearoyl-CoA desaturase-1. Curr Opin Lipidol. 2003;14:255-61.
-
(2003)
Curr Opin Lipidol
, vol.14
, pp. 255-261
-
-
Ntambi, J.M.1
Miyazaki, M.2
-
2
-
-
0345276007
-
Regulation of stearoyl-CoA desaturases and role in metabolism
-
Ntambi JM, Miyazaki M. Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res. 2004;43:91-104.
-
(2004)
Prog Lipid Res
, vol.43
, pp. 91-104
-
-
Ntambi, J.M.1
Miyazaki, M.2
-
3
-
-
0035862555
-
Scd3-a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin
-
Zheng Y, Prouty SM, Harmon A, Sundberg JP, Stenn KS, Parimoo S. Scd3-a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin. Genomics. 2001;71:182-91.
-
(2001)
Genomics
, vol.71
, pp. 182-191
-
-
Zheng, Y.1
Prouty, S.M.2
Harmon, A.3
Sundberg, J.P.4
Stenn, K.S.5
Parimoo, S.6
-
4
-
-
0032054936
-
A cluster of stearoyl CoA desaturase genes, Scd1 and Scd2, on mouse chromosome 19
-
Tabor DE, Xia YR, Mehrabian M, Edwards PA, Lusis AJ. A cluster of stearoyl CoA desaturase genes, Scd1 and Scd2, on mouse chromosome 19. Mamm Genome. 1998;9:341-2.
-
(1998)
Mamm Genome
, vol.9
, pp. 341-342
-
-
Tabor, D.E.1
Xia, Y.R.2
Mehrabian, M.3
Edwards, P.A.4
Lusis, A.J.5
-
5
-
-
0141780830
-
Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors
-
Miyazaki M, Jacobson MJ, Man WC, Cohen P, Asilmaz E, Friedman JM, Ntambi JM. Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. J Biol Chem. 2003;278:33904-11.
-
(2003)
J Biol Chem
, vol.278
, pp. 33904-33911
-
-
Miyazaki, M.1
Jacobson, M.J.2
Man, W.C.3
Cohen, P.4
Asilmaz, E.5
Friedman, J.M.6
Ntambi, J.M.7
-
6
-
-
19744365544
-
Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates
-
Wang J, Yu L, Schmidt RE, Su C, Huang X, Gould K, Cao G. Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates. Biochem Biophys Res Commun. 2005;332:735-42.
-
(2005)
Biochem Biophys Res Commun
, vol.332
, pp. 735-742
-
-
Wang, J.1
Yu, L.2
Schmidt, R.E.3
Su, C.4
Huang, X.5
Gould, K.6
Cao, G.7
-
7
-
-
0033563109
-
Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites
-
Zhang L, Ge L, Parimoo S, Stenn K, Prouty SM. Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites. Biochem J. 1999;340:255-64.
-
(1999)
Biochem J
, vol.340
, pp. 255-264
-
-
Zhang, L.1
Ge, L.2
Parimoo, S.3
Stenn, K.4
Prouty, S.M.5
-
8
-
-
67650088283
-
Biochemical and physiological function of stearoyl-CoA desaturase
-
Paton CM, Ntambi JM. Biochemical and physiological function of stearoyl-CoA desaturase. Am J Physiol Endocrinol Metab. 2009;297: E28-37.
-
(2009)
Am J Physiol Endocrinol Metab.
, vol.297
-
-
Paton, C.M.1
Ntambi, J.M.2
-
9
-
-
43249127067
-
Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism
-
Flowers MT, Ntambi JM. Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism. Curr Opin Lipidol. 2008;19:248-56.
-
(2008)
Curr Opin Lipidol
, vol.19
, pp. 248-256
-
-
Flowers, M.T.1
Ntambi, J.M.2
-
10
-
-
0035914369
-
Oleoyl-CoA is the major de novo product of stearoyl-CoA desaturase 1 gene isoform and substrate for the biosynthesis of the Harderian gland 1-alkyl-2,3-diacylglycerol
-
Miyazaki M, Kim HJ, Man WC, Ntambi JM. Oleoyl-CoA is the major de novo product of stearoyl-CoA desaturase 1 gene isoform and substrate for the biosynthesis of the Harderian gland 1-alkyl-2,3-diacylglycerol. J Biol Chem. 2001;276:39455-61.
-
(2001)
J Biol Chem
, vol.276
, pp. 39455-39461
-
-
Miyazaki, M.1
Kim, H.J.2
Man, W.C.3
Ntambi, J.M.4
-
11
-
-
0034254990
-
The N terminus of microsomal delta 9 stearoyl-CoA desaturase contains the sequence determinant for its rapid degradation
-
Mziaut H, Korza G, Ozols J. The N terminus of microsomal delta 9 stearoyl-CoA desaturase contains the sequence determinant for its rapid degradation. Proc Natl Acad Sci USA. 2000;97:8883-8.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8883-8888
-
-
Mziaut, H.1
Korza, G.2
Ozols, J.3
-
12
-
-
33745496962
-
Ubiquitin-proteasome-dependent degradation of mammalian ER stearoyl-CoA desaturase
-
Kato H, Sakaki K, Mihara K. Ubiquitin-proteasome-dependent degradation of mammalian ER stearoyl-CoA desaturase. J Cell Sci. 2006; 119:2342-53.
-
(2006)
J Cell Sci
, vol.119
, pp. 2342-2353
-
-
Kato, H.1
Sakaki, K.2
Mihara, K.3
-
13
-
-
0026745069
-
Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver
-
Ntambi JM. Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver. J Biol Chem. 1992;267:10925-30.
-
(1992)
J Biol Chem
, vol.267
, pp. 10925-10930
-
-
Ntambi, J.M.1
-
14
-
-
0028081005
-
Insulin and dietary fructose induce stearoyl-CoA desaturase 1 gene expression of diabetic mice
-
Waters KM, Ntambi JM. Insulin and dietary fructose induce stearoyl-CoA desaturase 1 gene expression of diabetic mice. J Biol Chem. 1994; 269:27773-7.
-
(1994)
J Biol Chem
, vol.269
, pp. 27773-27777
-
-
Waters, K.M.1
Ntambi, J.M.2
-
15
-
-
0032532050
-
Glucose induces expression of stearoyl-CoA desaturase in 3T3-L1 adipocytes
-
Jones BH, Standridge MK, Claycombe KJ, Smith PJ, Moustaid-Moussa N. Glucose induces expression of stearoyl-CoA desaturase in 3T3-L1 adipocytes. Biochem J. 1998;335:405-8.
-
(1998)
Biochem J
, vol.335
, pp. 405-408
-
-
Jones, B.H.1
Standridge, M.K.2
Claycombe, K.J.3
Smith, P.J.4
Moustaid-Moussa, N.5
-
16
-
-
0036795623
-
Dietary cholesterol opposes PUFAmediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism
-
Kim HJ, Miyazaki M, Ntambi JM. Dietary cholesterol opposes PUFAmediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism. J Lipid Res. 2002;43:1750-7.
-
(2002)
J Lipid Res
, vol.43
, pp. 1750-1757
-
-
Kim, H.J.1
Miyazaki, M.2
Ntambi, J.M.3
-
18
-
-
0344177201
-
Molecular targets of 1,25(OH)2D3 in HC11 normal mouse mammary cell line
-
Katayama ML, Pasini FS, Folgueira MA, Snitcovsky IM, Brentani MM. Molecular targets of 1,25(OH)2D3 in HC11 normal mouse mammary cell line. J Steroid Biochem Mol Biol. 2003;84:57-69.
-
(2003)
J Steroid Biochem Mol Biol
, vol.84
, pp. 57-69
-
-
Katayama, M.L.1
Pasini, F.S.2
Folgueira, M.A.3
Snitcovsky, I.M.4
Brentani, M.M.5
-
19
-
-
0029983561
-
Polyunsaturated fatty acids inhibit hepatic stearoyl-CoA desaturase-1 gene in diabetic mice
-
Waters KM, Ntambi JM. Polyunsaturated fatty acids inhibit hepatic stearoyl-CoA desaturase-1 gene in diabetic mice. Lipids. 1996;31 Suppl: S33-6.
-
(1996)
Lipids.
, vol.31
, Issue.SUPPL
-
-
Waters, K.M.1
Ntambi, J.M.2
-
20
-
-
0033929212
-
The trans-10,cis-12 isomer of conjugated linoleic acid downregulates stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes
-
Choi Y, Kim YC, Han YB, Park Y, Pariza MW, Ntambi JM. The trans-10,cis-12 isomer of conjugated linoleic acid downregulates stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes. J Nutr. 2000;130:1920-4.
-
(2000)
J Nutr
, vol.130
, pp. 1920-1924
-
-
Choi, Y.1
Kim, Y.C.2
Han, Y.B.3
Park, Y.4
Pariza, M.W.5
Ntambi, J.M.6
-
21
-
-
0034847971
-
Targeted disruption of stearoyl-CoA desaturase1 gene in mice causes atrophy of sebaceous and meibomian glands and depletion of wax esters in the eyelid
-
Miyazaki M, Man WC, Ntambi JM. Targeted disruption of stearoyl-CoA desaturase1 gene in mice causes atrophy of sebaceous and meibomian glands and depletion of wax esters in the eyelid. J Nutr. 2001;131:2260-8.
-
(2001)
J Nutr
, vol.131
, pp. 2260-2268
-
-
Miyazaki, M.1
Man, W.C.2
Ntambi, J.M.3
-
22
-
-
36448991861
-
Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis
-
Miyazaki M, Flowers MT, Sampath H, Chu K, Otzelberger C, Liu X, Ntambi JM. Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab. 2007;6:484-96.
-
(2007)
Cell Metab
, vol.6
, pp. 484-496
-
-
Miyazaki, M.1
Flowers, M.T.2
Sampath, H.3
Chu, K.4
Otzelberger, C.5
Liu, X.6
Ntambi, J.M.7
-
23
-
-
67749111842
-
Skin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat dietinduced obesity
-
Sampath H, Flowers MT, Liu X, Paton CM, Sullivan R, Chu K, Zhao M, Ntambi JM. Skin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat dietinduced obesity. J Biol Chem. 2009;284:19961-73.
-
(2009)
J Biol Chem
, vol.284
, pp. 19961-19973
-
-
Sampath, H.1
Flowers, M.T.2
Liu, X.3
Paton, C.M.4
Sullivan, R.5
Chu, K.6
Zhao, M.7
Ntambi, J.M.8
-
24
-
-
0032726605
-
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse
-
Zheng Y, Eilertsen KJ, Ge L, Zhang L, Sundberg JP, Prouty SM, Stenn KS, Parimoo S. Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse. Nat Genet. 1999;23:268-70.
-
(1999)
Nat Genet
, vol.23
, pp. 268-270
-
-
Zheng, Y.1
Eilertsen, K.J.2
Ge, L.3
Zhang, L.4
Sundberg, J.P.5
Prouty, S.M.6
Stenn, K.S.7
Parimoo, S.8
-
25
-
-
20144388684
-
Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1
-
Jiang G, Li Z, Liu F, Ellsworth K, Dallas-Yang Q, Wu M, Ronan J, Esau C, Murphy C, et al. Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1. J Clin Invest. 2005;115:1030-8.
-
(2005)
J Clin Invest
, vol.115
, pp. 1030-1038
-
-
Jiang, G.1
Li, Z.2
Liu, F.3
Ellsworth, K.4
Dallas-Yang, Q.5
Wu, M.6
Ronan, J.7
Esau, C.8
Murphy, C.9
-
26
-
-
12144268751
-
Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue
-
Rahman SM, Dobrzyn A, Lee SH, Dobrzyn P, Miyazaki M, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue. Am J Physiol Endocrinol Metab. 2005;288:E381-7.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Rahman, S.M.1
Dobrzyn, A.2
Lee, S.H.3
Dobrzyn, P.4
Miyazaki, M.5
Ntambi, J.M.6
-
27
-
-
2942588527
-
Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms
-
Miyazaki M, Dobrzyn A, Man WC, Chu K, Sampath H, Kim HJ, Ntambi JM. Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. J Biol Chem. 2004;279:25164-71.
-
(2004)
J Biol Chem
, vol.279
, pp. 25164-25171
-
-
Miyazaki, M.1
Dobrzyn, A.2
Man, W.C.3
Chu, K.4
Sampath, H.5
Kim, H.J.6
Ntambi, J.M.7
-
28
-
-
0141813781
-
Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle
-
Rahman SM, Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle. Proc Natl Acad Sci USA. 2003;100:11110-5.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11110-11115
-
-
Rahman, S.M.1
Dobrzyn, A.2
Dobrzyn, P.3
Lee, S.H.4
Miyazaki, M.5
Ntambi, J.M.6
-
29
-
-
0037143752
-
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
-
Ntambi JM, MiyazakiM, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, et al. Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc Natl Acad Sci USA. 2002; 99:11482-6.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11482-11486
-
-
Ntambi, J.M.1
Miyazaki, M.2
Stoehr, J.P.3
Lan, H.4
Kendziorski, C.M.5
Yandell, B.S.6
Song, Y.7
Cohen, P.8
Friedman, J.M.9
-
30
-
-
60849136007
-
Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice
-
Miyazaki M, Sampath H, Liu X, Flowers MT, Chu K, Dobrzyn A, Ntambi JM. Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice. Biochem Biophys Res Commun. 2009;380:818-22.
-
(2009)
Biochem Biophys Res Commun
, vol.380
, pp. 818-822
-
-
Miyazaki, M.1
Sampath, H.2
Liu, X.3
Flowers, M.T.4
Chu, K.5
Dobrzyn, A.6
Ntambi, J.M.7
-
31
-
-
0029077405
-
The regulation of stearoyl-CoA desaturase (SCD)
-
Ntambi JM. The regulation of stearoyl-CoA desaturase (SCD). Prog Lipid Res. 1995;34:139-50.
-
(1995)
Prog Lipid Res
, vol.34
, pp. 139-150
-
-
Ntambi, J.M.1
-
32
-
-
0032871502
-
Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol
-
Ntambi JM. Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J Lipid Res. 1999;40:1549-58.
-
(1999)
J Lipid Res
, vol.40
, pp. 1549-1558
-
-
Ntambi, J.M.1
-
33
-
-
77956290719
-
Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer
-
Igal RA. Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer. Carcinogenesis. 2010;31:1509-15.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1509-1515
-
-
Igal, R.A.1
-
34
-
-
0028246883
-
Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues
-
Li J, Ding SF, Habib NA, Fermor BF, Wood CB, Gilmour RS. Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues. Int J Cancer. 1994;57:348-52.
-
(1994)
Int J Cancer
, vol.57
, pp. 348-352
-
-
Li, J.1
Ding, S.F.2
Habib, N.A.3
Fermor, B.F.4
Wood, C.B.5
Gilmour, R.S.6
-
35
-
-
0023204673
-
Stearic acid and carcinogenesis
-
Habib NA, Wood CB, Apostolov K, Barker W, Hershman MJ, Aslam M, Heinemann D, Fermor B, et al. Stearic acid and carcinogenesis. Br J Cancer. 1987;56:455-8.
-
(1987)
Br J Cancer
, vol.56
, pp. 455-458
-
-
Habib, N.A.1
Wood, C.B.2
Apostolov, K.3
Barker, W.4
Hershman, M.J.5
Aslam, M.6
Heinemann, D.7
Fermor, B.8
-
36
-
-
13644263225
-
High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts
-
Scaglia N, Caviglia JM, Igal RA. High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts. Biochim Biophys Acta. 2005;1687:141-51.
-
(2005)
Biochim Biophys Acta
, vol.1687
, pp. 141-151
-
-
Scaglia, N.1
Caviglia, J.M.2
Igal, R.A.3
-
37
-
-
69449099939
-
Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPK
-
Scaglia N, Chisholm JW, Igal RA. Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPK. PLoS ONE. 2009;4:e6812.
-
(2009)
PLoS ONE.
, vol.4
-
-
Scaglia, N.1
Chisholm, J.W.2
Igal, R.A.3
-
38
-
-
77956210076
-
Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells
-
Hess D, Chisholm JW, Igal RA. Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells. PLoS ONE. 2010;5:e11394.
-
(2010)
PLoS ONE.
, vol.5
-
-
Hess, D.1
Chisholm, J.W.2
Igal, R.A.3
-
39
-
-
77953471622
-
Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice
-
Fritz V, Benfodda Z, Rodier G, Henriquet C, Iborra F, Avances C, Allory Y, de la Taille A, Culine S, et al. Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice. Mol Cancer Ther. 2010;9:1740-54.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1740-1754
-
-
Fritz, V.1
Benfodda, Z.2
Rodier, G.3
Henriquet, C.4
Iborra, F.5
Avances, C.6
Allory, Y.7
De La Taille, A.8
Culine, S.9
-
40
-
-
34249285532
-
Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen
-
Morgan-Lappe SE, Tucker LA, Huang X, Zhang Q, Sarthy AV, Zakula D, Vernetti L, Schurdak M, Wang J, et al. Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen. Cancer Res. 2007;67:4390-8.
-
(2007)
Cancer Res
, vol.67
, pp. 4390-4398
-
-
Morgan-Lappe, S.E.1
Tucker, L.A.2
Huang, X.3
Zhang, Q.4
Sarthy, A.V.5
Zakula, D.6
Vernetti, L.7
Schurdak, M.8
Wang, J.9
-
41
-
-
14844324489
-
Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma
-
Moore S, Knudsen B, True LD, Hawley S, Etzioni R, Wade C, Gifford D, Coleman I, Nelson PS. Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma. Int J Cancer. 2005;114: 563-71.
-
(2005)
Int J Cancer
, vol.114
, pp. 563-571
-
-
Moore, S.1
Knudsen, B.2
True, L.D.3
Hawley, S.4
Etzioni, R.5
Wade, C.6
Gifford, D.7
Coleman, I.8
Nelson, P.S.9
-
42
-
-
0034730532
-
The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1
-
Miyazaki M, Kim YC, Gray-Keller MP, Attie AD, Ntambi JM. The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1. J Biol Chem. 2000;275:30132-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 30132-30138
-
-
Miyazaki, M.1
Kim, Y.C.2
Gray-Keller, M.P.3
Attie, A.D.4
Ntambi, J.M.5
-
43
-
-
69249205739
-
Obesity, inflammation, and atherosclerosis
-
Rocha VZ, Libby P. Obesity, inflammation, and atherosclerosis. Nat Rev Cardiol. 2009;6:399-409.
-
(2009)
Nat Rev Cardiol
, vol.6
, pp. 399-409
-
-
Rocha, V.Z.1
Libby, P.2
-
45
-
-
0033957165
-
Dietary polyunsaturated fatty acids and inflammatory mediator production
-
James MJ, Gibson RA, Cleland LG. Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr. 2000;71: S343-8.
-
(2000)
Am J Clin Nutr.
, vol.71
-
-
James, M.J.1
Gibson, R.A.2
Cleland, L.G.3
-
47
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest. 2006;116:3015-25.
-
(2006)
J Clin Invest
, vol.116
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
48
-
-
3042824524
-
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway
-
Feldstein AE, Werneburg NW, Canbay A, Guicciardi ME, Bronk SF, Rydzewski R, Burgart LJ, Gores GJ. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology. 2004;40:185-94.
-
(2004)
Hepatology
, vol.40
, pp. 185-194
-
-
Feldstein, A.E.1
Werneburg, N.W.2
Canbay, A.3
Guicciardi, M.E.4
Bronk, S.F.5
Rydzewski, R.6
Burgart, L.J.7
Gores, G.J.8
-
49
-
-
72249085560
-
Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes
-
Kadotani A, Tsuchiya Y, Hatakeyama H, Katagiri H, Kanzaki M. Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes. Am J Physiol Endocrinol Metab. 2009;297:E1291-303.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
-
-
Kadotani, A.1
Tsuchiya, Y.2
Hatakeyama, H.3
Katagiri, H.4
Kanzaki, M.5
-
50
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
-
Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, et al. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem. 2007;282:35279-92.
-
(2007)
J Biol Chem
, vol.282
, pp. 35279-35292
-
-
Nguyen, M.T.1
Favelyukis, S.2
Nguyen, A.K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-Bryan, R.7
Glass, C.K.8
Neels, J.G.9
-
51
-
-
0036212847
-
A trip through my life with an immunological theme
-
Janeway CA Jr. A trip through my life with an immunological theme. Annu Rev Immunol. 2002;20:1-28.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 1-28
-
-
Janeway Jr., C.A.1
-
53
-
-
51349156218
-
Insulin sensitivity: modulation by nutrients and inflammation
-
Schenk S, Saberi M, Olefsky JM. Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest. 2008;118:2992-3002.
-
(2008)
J Clin Invest
, vol.118
, pp. 2992-3002
-
-
Schenk, S.1
Saberi, M.2
Olefsky, J.M.3
-
54
-
-
77955657267
-
Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture
-
Defronzo RA. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture. Diabetologia. 2010;53:1270-87.
-
(2010)
Diabetologia
, vol.53
, pp. 1270-1287
-
-
Defronzo, R.A.1
-
55
-
-
76349105718
-
Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome
-
Prieur X, Roszer T, Ricote M. Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome. Biochim Biophys Acta. 2010;1801:327-37.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 327-337
-
-
Prieur, X.1
Roszer, T.2
Ricote, M.3
-
56
-
-
73349117487
-
Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome
-
Fessler MB, Rudel LL, Brown JM. Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome. Curr Opin Lipidol. 2009; 20:379-85.
-
(2009)
Curr Opin Lipidol
, vol.20
, pp. 379-385
-
-
Fessler, M.B.1
Rudel, L.L.2
Brown, J.M.3
-
57
-
-
77949874469
-
Obesity, inflammation, and cardiovascular risk
-
Mathieu P, Lemieux I, Despres JP. Obesity, inflammation, and cardiovascular risk. Clin Pharmacol Ther. 2010;87:407-16.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 407-416
-
-
Mathieu, P.1
Lemieux, I.2
Despres, J.P.3
-
58
-
-
77957078371
-
Endoplasmic reticulum stress and inflammation in obesity and diabetes
-
Hummasti S, Hotamisligil GS. Endoplasmic reticulum stress and inflammation in obesity and diabetes. Circ Res. 2010;107:579-91.
-
(2010)
Circ Res
, vol.107
, pp. 579-591
-
-
Hummasti, S.1
Hotamisligil, G.S.2
-
59
-
-
33845574569
-
Mice fed a lipogenic methionine-cholinedeficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1
-
Rizki G, Arnaboldi L, Gabrielli B, Yan J, Lee GS, Ng RK, Turner SM, Badger TM, Pitas RE, et al. Mice fed a lipogenic methionine-cholinedeficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1. J Lipid Res. 2006;47:2280-90.
-
(2006)
J Lipid Res
, vol.47
, pp. 2280-2290
-
-
Rizki, G.1
Arnaboldi, L.2
Gabrielli, B.3
Yan, J.4
Lee, G.S.5
Ng, R.K.6
Turner, S.M.7
Badger, T.M.8
Pitas, R.E.9
-
60
-
-
65549136260
-
Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase
-
Li ZZ, Berk M, Mcintyre TM, Feldstein AE. Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase. J Biol Chem. 2009;284:5637-44.
-
(2009)
J Biol Chem
, vol.284
, pp. 5637-5644
-
-
Li, Z.Z.1
Berk, M.2
Mcintyre, T.M.3
Feldstein, A.E.4
-
61
-
-
45449126566
-
Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet
-
Flowers MT, Keller MP, Choi Y, Lan H, Kendziorski C, Ntambi JM, Attie AD. Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet. Physiol Genomics. 2008;33:361-72.
-
(2008)
Physiol Genomics
, vol.33
, pp. 361-372
-
-
Flowers, M.T.1
Keller, M.P.2
Choi, Y.3
Lan, H.4
Kendziorski, C.5
Ntambi, J.M.6
Attie, A.D.7
-
62
-
-
59049096686
-
Stearoyl-CoA desaturase 1 deficiency protects mice from immunemediated liver injury
-
Feng D, Wang Y, Mei Y, Xu Y, Xu H, Lu Y, Luo Q, Zhou S, Kong X, et al. Stearoyl-CoA desaturase 1 deficiency protects mice from immunemediated liver injury. Lab Invest. 2009;89:222-30.
-
(2009)
Lab Invest
, vol.89
, pp. 222-230
-
-
Feng, D.1
Wang, Y.2
Mei, Y.3
Xu, Y.4
Xu, H.5
Lu, Y.6
Luo, Q.7
Zhou, S.8
Kong, X.9
-
63
-
-
0030806496
-
Experimental hepatitis and role of cytokines
-
Tiegs G. Experimental hepatitis and role of cytokines. Acta Gastroenterol Belg. 1997;60:176-9.
-
(1997)
Acta Gastroenterol Belg
, vol.60
, pp. 176-179
-
-
Tiegs, G.1
-
65
-
-
77957121400
-
Reduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing beta-cells
-
Thorn K, Hovsepyan M, Bergsten P. Reduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing beta-cells. Lipids Health Dis. 2010;9:108.
-
(2010)
Lipids Health Dis
, vol.9
, pp. 108
-
-
Thorn, K.1
Hovsepyan, M.2
Bergsten, P.3
-
66
-
-
70349661825
-
Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalphadependent stearoyl-coenzyme A desaturase
-
Hellemans KH, Hannaert JC, Denys B, Steffensen KR, Raemdonck C, Martens GA, Van Veldhoven PP, Gustafsson JA, Pipeleers D. Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalphadependent stearoyl-coenzyme A desaturase. PLoS ONE. 2009;4:e7266.
-
(2009)
PLoS ONE.
, vol.4
-
-
Hellemans, K.H.1
Hannaert, J.C.2
Denys, B.3
Steffensen, K.R.4
Raemdonck, C.5
Martens, G.A.6
Van Veldhoven, P.P.7
Gustafsson, J.A.8
Pipeleers, D.9
-
67
-
-
0036315888
-
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated
-
Lupi R, Dotta F, Marselli L, Del Guerra S, Masini M, Santangelo C, Patane G, Boggi U, Piro S, et al. Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated. Diabetes. 2002; 51:1437-42.
-
(2002)
Diabetes
, vol.51
, pp. 1437-1442
-
-
Lupi, R.1
Dotta, F.2
Marselli, L.3
Del Guerra, G.4
Masini, M.5
Santangelo, C.6
Patane, G.7
Boggi, U.8
Piro, S.9
-
68
-
-
77952426387
-
Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discovery
-
Brown JM, Rudel LL. Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discovery. Curr Opin Lipidol. 2010;21:192-7.
-
(2010)
Curr Opin Lipidol
, vol.21
, pp. 192-197
-
-
Brown, J.M.1
Rudel, L.L.2
-
69
-
-
25844454854
-
Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis
-
Busch AK, Gurisik E, Cordery DV, Sudlow M, Denyer GS, Laybutt DR, Hughes WE, Biden TJ. Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis. Diabetes. 2005;54:2917-24.
-
(2005)
Diabetes
, vol.54
, pp. 2917-2924
-
-
Busch, A.K.1
Gurisik, E.2
Cordery, D.V.3
Sudlow, M.4
Denyer, G.S.5
Laybutt, D.R.6
Hughes, W.E.7
Biden, T.J.8
-
70
-
-
0345354674
-
Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function
-
Maedler K, Oberholzer J, Bucher P, Spinas GA, Donath MY. Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. Diabetes. 2003;52:726-33.
-
(2003)
Diabetes
, vol.52
, pp. 726-733
-
-
Maedler, K.1
Oberholzer, J.2
Bucher, P.3
Spinas, G.A.4
Donath, M.Y.5
-
71
-
-
59049098636
-
Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity
-
Flowers MT, Ntambi JM. Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity. Biochim Biophys Acta. 2009; 1791:85-91.
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 85-91
-
-
Flowers, M.T.1
Ntambi, J.M.2
-
72
-
-
34248198871
-
Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice
-
Flowers JB, Rabaglia ME, Schueler KL, Flowers MT, Lan H, Keller MP, Ntambi JM, Attie AD. Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice. Diabetes. 2007;56:1228-39.
-
(2007)
Diabetes
, vol.56
, pp. 1228-1239
-
-
Flowers, J.B.1
Rabaglia, M.E.2
Schueler, K.L.3
Flowers, M.T.4
Lan, H.5
Keller, M.P.6
Ntambi, J.M.7
Attie, A.D.8
-
73
-
-
73849108138
-
Loss of stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate
-
Liu X, Miyazaki M, Flowers MT, Sampath H, Zhao M, Chu K, Paton CM, Joo DS, Ntambi JM. Loss of stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate. Arterioscler Thromb Vasc Biol. 2010;30:31-8.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 31-38
-
-
Liu, X.1
Miyazaki, M.2
Flowers, M.T.3
Sampath, H.4
Zhao, M.5
Chu, K.6
Paton, C.M.7
Joo, D.S.8
Ntambi, J.M.9
-
74
-
-
58649105336
-
Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice
-
Menghini R, Menini S, Amoruso R, Fiorentino L, Casagrande V, Marzano V, Tornei F, Bertucci P, Iacobini C, et al. Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice. Gastroenterology. 2009;136:663-72 e4.
-
(2009)
Gastroenterology
, vol.136
-
-
Menghini, R.1
Menini, S.2
Amoruso, R.3
Fiorentino, L.4
Casagrande, V.5
Marzano, V.6
Tornei, F.7
Bertucci, P.8
Iacobini, C.9
-
75
-
-
0242349259
-
beta-Amyloid-specific upregulation of stearoyl coenzyme A desaturase-1 in macrophages
-
Uryu S, Tokuhiro S, Oda T. beta-Amyloid-specific upregulation of stearoyl coenzyme A desaturase-1 in macrophages. Biochem Biophys Res Commun. 2003;303:302-5.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 302-305
-
-
Uryu, S.1
Tokuhiro, S.2
Oda, T.3
-
76
-
-
61549135741
-
Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis
-
Macdonald ML, van Eck M, Hildebrand RB, Wong BW, Bissada N, Ruddle P, Kontush A, Hussein H, Pouladi MA, et al. Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29:341-7.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 341-347
-
-
Macdonald, M.L.1
Van Eck, M.2
Hildebrand, R.B.3
Wong, B.W.4
Bissada, N.5
Ruddle, P.6
Kontush, A.7
Hussein, H.8
Pouladi, M.A.9
-
77
-
-
54049132164
-
Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis
-
Brown JM, Chung S, Sawyer JK, Degirolamo C, Alger HM, Nguyen T, Zhu X, Duong MN, Wibley AL, et al. Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis. Circulation. 2008;118:1467-75.
-
(2008)
Circulation
, vol.118
, pp. 1467-1475
-
-
Brown, J.M.1
Chung, S.2
Sawyer, J.K.3
Degirolamo, C.4
Alger, H.M.5
Nguyen, T.6
Zhu, X.7
Duong, M.N.8
Wibley, A.L.9
-
78
-
-
71549152580
-
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis
-
Erbay E, Babaev VR, Mayers JR, Makowski L, Charles KN, Snitow ME, Fazio S, Wiest MM, Watkins SM, et al. Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis. Nat Med. 2009;15:1383-91.
-
(2009)
Nat Med
, vol.15
, pp. 1383-1391
-
-
Erbay, E.1
Babaev, V.R.2
Mayers, J.R.3
Makowski, L.4
Charles, K.N.5
Snitow, M.E.6
Fazio, S.7
Wiest, M.M.8
Watkins, S.M.9
-
79
-
-
0026709207
-
Stearoyl-CoA desaturase gene expression in lymphocytes
-
Tebbey PW, Buttke TM. Stearoyl-CoA desaturase gene expression in lymphocytes. Biochem Biophys Res Commun. 1992;186:531-6.
-
(1992)
Biochem Biophys Res Commun
, vol.186
, pp. 531-536
-
-
Tebbey, P.W.1
Buttke, T.M.2
-
80
-
-
60649112430
-
Relationships between serum fatty acid composition and multiple markers of inflammation and endothelial function in an elderly population
-
Petersson H, Lind L, Hulthe J, Elmgren A, Cederholm T, Riserus U. Relationships between serum fatty acid composition and multiple markers of inflammation and endothelial function in an elderly population. Atherosclerosis. 2009;203:298-303.
-
(2009)
Atherosclerosis
, vol.203
, pp. 298-303
-
-
Petersson, H.1
Lind, L.2
Hulthe, J.3
Elmgren, A.4
Cederholm, T.5
Riserus, U.6
-
81
-
-
45549107634
-
Serum fatty acid composition and indices of stearoyl-CoA desaturase activity are associated with systemic inflammation: longitudinal analyses in middle-aged men
-
Petersson H, Basu S, Cederholm T, Riserus U. Serum fatty acid composition and indices of stearoyl-CoA desaturase activity are associated with systemic inflammation: longitudinal analyses in middle-aged men. Br J Nutr. 2008;99:1186-9.
-
(2008)
Br J Nutr
, vol.99
, pp. 1186-1189
-
-
Petersson, H.1
Basu, S.2
Cederholm, T.3
Riserus, U.4
-
82
-
-
38049169032
-
Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice
-
Macdonald ML, Singaraja RR, Bissada N, Ruddle P, Watts R, Karasinska JM, Gibson WT, Fievet C, Vance JE, et al. Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice. J Lipid Res. 2008;49:217-29.
-
(2008)
J Lipid Res
, vol.49
, pp. 217-229
-
-
Macdonald, M.L.1
Singaraja, R.R.2
Bissada, N.3
Ruddle, P.4
Watts, R.5
Karasinska, J.M.6
Gibson, W.T.7
Fievet, C.8
Vance, J.E.9
-
83
-
-
34250163879
-
Chronic intermittent hypoxia induces atherosclerosis
-
Savransky V, Nanayakkara A, Li J, Bevans S, Smith PL, Rodriguez A, Polotsky VY. Chronic intermittent hypoxia induces atherosclerosis. Am J Respir Crit Care Med. 2007;175:1290-7.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 1290-1297
-
-
Savransky, V.1
Nanayakkara, A.2
Li, J.3
Bevans, S.4
Smith, P.L.5
Rodriguez, A.6
Polotsky, V.Y.7
-
85
-
-
26244450659
-
Intermittent hypoxia induces hyperlipidemia in lean mice
-
Li J, Thorne LN, Punjabi NM, Sun CK, Schwartz AR, Smith PL, Marino RL, Rodriguez A, Hubbard WC, et al. Intermittent hypoxia induces hyperlipidemia in lean mice. Circ Res. 2005;97:698-706.
-
(2005)
Circ Res
, vol.97
, pp. 698-706
-
-
Li, J.1
Thorne, L.N.2
Punjabi, N.M.3
Sun, C.K.4
Schwartz, A.R.5
Smith, P.L.6
Marino, R.L.7
Rodriguez, A.8
Hubbard, W.C.9
-
86
-
-
58149145901
-
Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase
-
Savransky V, Jun J, Li J, Nanayakkara A, Fonti S, Moser AB, Steele KE, Schweitzer MA, Patil SP, et al. Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase. Circ Res. 2008;103:1173-80.
-
(2008)
Circ Res
, vol.103
, pp. 1173-1180
-
-
Savransky, V.1
Jun, J.2
Li, J.3
Nanayakkara, A.4
Fonti, S.5
Moser, A.B.6
Steele, K.E.7
Schweitzer, M.A.8
Patil, S.P.9
-
88
-
-
37349078272
-
Insulin resistance and endothelial cell dysfunction: studies in mammalian models
-
Kearney MT, Duncan ER, Kahn M, Wheatcroft SB. Insulin resistance and endothelial cell dysfunction: studies in mammalian models. Exp Physiol. 2008;93:158-63.
-
(2008)
Exp Physiol
, vol.93
, pp. 158-163
-
-
Kearney, M.T.1
Duncan, E.R.2
Kahn, M.3
Wheatcroft, S.B.4
-
89
-
-
33745948085
-
Insulin resistance and endothelial dysfunction: the road map to cardiovascular diseases
-
Cersosimo E, Defronzo RA. Insulin resistance and endothelial dysfunction: the road map to cardiovascular diseases. Diabetes Metab Res Rev. 2006;22:423-36.
-
(2006)
Diabetes Metab Res Rev
, vol.22
, pp. 423-436
-
-
Cersosimo, E.1
Defronzo, R.A.2
-
90
-
-
57749177096
-
Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity
-
BakkerW, Eringa EC, Sipkema P, van Hinsbergh VW. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res. 2009;335:165-89.
-
(2009)
Cell Tissue Res
, vol.335
, pp. 165-189
-
-
Bakker, W.1
Eringa, E.C.2
Sipkema, P.3
Van Hinsbergh, V.W.4
-
91
-
-
58149328550
-
Effect of endotheliumspecific insulin resistance on endothelial function in vivo
-
Duncan ER, Crossey PA, Walker S, Anilkumar N, Poston L, Douglas G, Ezzat VA, Wheatcroft SB, Shah AM, et al. Effect of endotheliumspecific insulin resistance on endothelial function in vivo. Diabetes. 2008;57:3307-14.
-
(2008)
Diabetes
, vol.57
, pp. 3307-3314
-
-
Duncan, E.R.1
Crossey, P.A.2
Walker, S.3
Anilkumar, N.4
Poston, L.5
Douglas, G.6
Ezzat, V.A.7
Wheatcroft, S.B.8
Shah, A.M.9
-
92
-
-
52649151321
-
Induction of stearoyl-CoA desaturase protects human arterial endothelial cells against lipotoxicity
-
Peter A, Weigert C, Staiger H, Rittig K, Cegan A, Lutz P, Machicao F, Haring HU, Schleicher E. Induction of stearoyl-CoA desaturase protects human arterial endothelial cells against lipotoxicity. Am J Physiol Endocrinol Metab. 2008;295:E339-49.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Peter, A.1
Weigert, C.2
Staiger, H.3
Rittig, K.4
Cegan, A.5
Lutz, P.6
Machicao, F.7
Haring, H.U.8
Schleicher, E.9
-
93
-
-
34247894035
-
Laminar shear stress up-regulates the expression of stearoyl-CoA desaturase-1 in vascular endothelial cells
-
Qin X, Tian J, Zhang P, Fan Y, Chen L, Guan Y, Fu Y, Zhu Y, Chien S, et al. Laminar shear stress up-regulates the expression of stearoyl-CoA desaturase-1 in vascular endothelial cells. Cardiovasc Res. 2007;74: 506-14.
-
(2007)
Cardiovasc Res
, vol.74
, pp. 506-514
-
-
Qin, X.1
Tian, J.2
Zhang, P.3
Fan, Y.4
Chen, L.5
Guan, Y.6
Fu, Y.7
Zhu, Y.8
Chien, S.9
-
94
-
-
13844250258
-
Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle
-
Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. Am J Physiol Endocrinol Metab. 2005;288:E599-607.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Dobrzyn, A.1
Dobrzyn, P.2
Lee, S.H.3
Miyazaki, M.4
Cohen, P.5
Asilmaz, E.6
Hardie, D.G.7
Friedman, J.M.8
Ntambi, J.M.9
-
95
-
-
33644821916
-
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans
-
Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, et al. Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab. 2005;2: 251-61.
-
(2005)
Cell Metab
, vol.2
, pp. 251-261
-
-
Hulver, M.W.1
Berggren, J.R.2
Carper, M.J.3
Miyazaki, M.4
Ntambi, J.M.5
Hoffman, E.P.6
Thyfault, J.P.7
Stevens, R.8
Dohm, G.L.9
-
96
-
-
34249915334
-
Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance
-
Schenk S, Horowitz JF. Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance. J Clin Invest. 2007;117:1690-8.
-
(2007)
J Clin Invest
, vol.117
, pp. 1690-1698
-
-
Schenk, S.1
Horowitz, J.F.2
-
97
-
-
33750906573
-
Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acidinduced skeletal muscle insulin resistance in vitro
-
Pinnamaneni SK, Southgate RJ, Febbraio MA, Watt MJ. Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acidinduced skeletal muscle insulin resistance in vitro. Diabetologia. 2006; 49:3027-37.
-
(2006)
Diabetologia
, vol.49
, pp. 3027-3037
-
-
Pinnamaneni, S.K.1
Southgate, R.J.2
Febbraio, M.A.3
Watt, M.J.4
-
98
-
-
68049142428
-
Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo
-
Peter A, Weigert C, Staiger H, Machicao F, Schick F, Machann J, Stefan N, Thamer C, Haring HU, et al. Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo. Diabetes. 2009;58:1757-65.
-
(2009)
Diabetes
, vol.58
, pp. 1757-1765
-
-
Peter, A.1
Weigert, C.2
Staiger, H.3
Machicao, F.4
Schick, F.5
Machann, J.6
Stefan, N.7
Thamer, C.8
Haring, H.U.9
-
100
-
-
23344436144
-
A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria
-
Georgel P, Crozat K, Lauth X, Makrantonaki E, Seltmann H, Sovath S, Hoebe K, Du X, Rutschmann S, et al. A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria. Infect Immun. 2005;73:4512-21.
-
(2005)
Infect Immun
, vol.73
, pp. 4512-4521
-
-
Georgel, P.1
Crozat, K.2
Lauth, X.3
Makrantonaki, E.4
Seltmann, H.5
Sovath, S.6
Hoebe, K.7
Du, X.8
Rutschmann, S.9
-
101
-
-
38649128825
-
Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis
-
Chen C, Shah YM, Morimura K, Krausz KW, Miyazaki M, Richardson TA, Morgan ET, Ntambi JM, Idle JR, et al. Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis. Cell Metab. 2008;7:135-47.
-
(2008)
Cell Metab
, vol.7
, pp. 135-147
-
-
Chen, C.1
Shah, Y.M.2
Morimura, K.3
Krausz, K.W.4
Miyazaki, M.5
Richardson, T.A.6
Morgan, E.T.7
Ntambi, J.M.8
Idle, J.R.9
|