Staphylococcus aureus Alpha Toxin Suppresses Effective Innate and Adaptive Immune Responses in a Murine Dermonecrosis Model

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Tkaczyk, Christine ^a   Hamilton, Melissa M ^a   Datta, Vivekananda ^a   Yang, Xiang Ping ^a   Hilliard, Jamese J ^a   Stephens, Geoffrey L ^a   Sadowska, Agnieszka ^a   Hua, Lei ^a   O'Day, Terrence ^a   Suzich, JoAnn ^a   Stover, Charles Kendall ^a   Sellman, Bret R ^a  

^a MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; INTERLEUKIN 17; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2A3; NEUTRALIZING ANTIBODY; STAPHYLOCOCCUS ALPHA TOXIN; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY AFFINITY; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL STRAIN; BACTERIUM MUTANT; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GAMMA DELTA T LYMPHOCYTE; IMMUNE DEFICIENCY; INNATE IMMUNITY; MOUSE; MOUSE MODEL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PASSIVE IMMUNIZATION; SKIN NECROSIS; STAPHYLOCOCCUS AUREUS; TH1 CELL; TH17 CELL;

ADAPTIVE IMMUNITY; ANIMALS; ANTIBODIES, NEUTRALIZING; BACTERIAL TOXINS; CHEMOKINES; DISEASE MODELS, ANIMAL; FEMALE; IMMUNITY, INNATE; INTERLEUKIN-17; MICE; MICE, INBRED BALB C; NECROSIS; SKIN; SOFT TISSUE INFECTIONS; STAPHYLOCOCCUS AUREUS; TH1 CELLS;

EID: 84884844749     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075103     Document Type: Article

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