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Volumn 65, Issue 1, 1997, Pages 179-184

Expression of an antisense hla fragment in Staphylococcus aureus reduces alpha-toxin production in vitro and attenuates lethal activity in a murine model

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL RNA; COMPLEMENTARY RNA; STAPHYLOCOCCUS VACCINE;

EID: 0031022928     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.1.179-184.1997     Document Type: Article
Times cited : (74)

References (41)
  • 1
    • 0028584334 scopus 로고
    • Inhibition of T7 RNA polymerase transcription by phosphate and phospho7 rothioate triplex-forming oligonucleotides targeted to a R ̇ Y site down-stream from the promoter
    • Alunni-Fabbroni, M., G. Manfioletti, G. Manzini, and L. E. Xodo. 1994. Inhibition of T7 RNA polymerase transcription by phosphate and phospho7 rothioate triplex-forming oligonucleotides targeted to a R ̇ Y site down-stream from the promoter. Eur. J. Biochem. 226:831-839.
    • (1994) Eur. J. Biochem. , vol.226 , pp. 831-839
    • Alunni-Fabbroni, M.1    Manfioletti, G.2    Manzini, G.3    Xodo, L.E.4
  • 2
    • 0024233053 scopus 로고
    • An unwinding activity that covalently modifies its double-stranded RNA substrate
    • Bass, B. L., and H. Weintraub. 1988. An unwinding activity that covalently modifies its double-stranded RNA substrate. Cell 55:1089-1098.
    • (1988) Cell , vol.55 , pp. 1089-1098
    • Bass, B.L.1    Weintraub, H.2
  • 3
    • 0024265414 scopus 로고
    • Assay of hemolytic toxins
    • Bernheimer, A. W. 1988. Assay of hemolytic toxins. Methods Enzymol. 165: 213-217.
    • (1988) Methods Enzymol. , vol.165 , pp. 213-217
    • Bernheimer, A.W.1
  • 4
    • 0013852911 scopus 로고
    • Staphylococcal alpha toxin
    • Bernheimer, A. W. 1965. Staphylococcal alpha toxin. Ann. N. Y. Acad. Sci. 128:112-123.
    • (1965) Ann. N. Y. Acad. Sci. , vol.128 , pp. 112-123
    • Bernheimer, A.W.1
  • 5
    • 0025787798 scopus 로고
    • Alpha-toxin of Staphylococcus aureus
    • Bhakdi, S., and J. Tranum-Jensen. 1991. Alpha-toxin of Staphylococcus aureus. Microbiol. Rev. 55:733-751.
    • (1991) Microbiol. Rev. , vol.55 , pp. 733-751
    • Bhakdi, S.1    Tranum-Jensen, J.2
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the determination of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the determination of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0029087544 scopus 로고
    • Protection of a T-cell line from human immunodeficiency virus replication by the stable expression of a short antisense RNA sequence carried by a shuttle RNA molecule
    • Cagnon, L., M. Cucchiarini, J.-C. Lefebvre, and A. Doglio. 1995. Protection of a T-cell line from human immunodeficiency virus replication by the stable expression of a short antisense RNA sequence carried by a shuttle RNA molecule. J. AIDS Hum. Retrovirol. 9:349-358.
    • (1995) J. AIDS Hum. Retrovirol. , vol.9 , pp. 349-358
    • Cagnon, L.1    Cucchiarini, M.2    Lefebvre, J.-C.3    Doglio, A.4
  • 8
    • 0017264506 scopus 로고
    • Purification of staphylococcal alphatoxin by adsorption chromalography on glass
    • Cassidy, P., and S. Harshman. 1976. Purification of staphylococcal alphatoxin by adsorption chromalography on glass. Infect. Immun. 13:982-986.
    • (1976) Infect. Immun. , vol.13 , pp. 982-986
    • Cassidy, P.1    Harshman, S.2
  • 9
    • 0026047599 scopus 로고
    • Expression of an antisense viral gene in transgenic tobacco confers resistance to the DNA virus tomato golden mosaic virus
    • Day, A. G., E. R. Bejarano, K. W. Buck, M. Burrell, and C. P. Lichtenstein. 1991. Expression of an antisense viral gene in transgenic tobacco confers resistance to the DNA virus tomato golden mosaic virus. Proc. Natl. Acad. Sci. USA 88:6721-6725.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6721-6725
    • Day, A.G.1    Bejarano, E.R.2    Buck, K.W.3    Burrell, M.4    Lichtenstein, C.P.5
  • 10
    • 0343123803 scopus 로고
    • Immunity to the staphylococci
    • J. O. Cohen (ed.), John Wiley & Sons, Inc., New York
    • Ekstedt, R. D. 1972. Immunity to the staphylococci, p. 385-392. In J. O. Cohen (ed.), The staphylococci. John Wiley & Sons, Inc., New York.
    • (1972) The Staphylococci , pp. 385-392
    • Ekstedt, R.D.1
  • 11
    • 0024041593 scopus 로고
    • Molecular Koch's postulates applied to microbial pathogenicity
    • Falkow, S. 1988. Molecular Koch's postulates applied to microbial pathogenicity. Rev. Infect. Dis. 10(Suppl. 2):S274-S276.
    • (1988) Rev. Infect. Dis. , vol.10 , Issue.2 SUPPL.
    • Falkow, S.1
  • 12
    • 0001432933 scopus 로고
    • Genetic studies of virulence factors of Stapliylococcus aureus: Properties of coagulase, γ-toxin, α-toxin, β-toxin, and protein A in the pathogenesis of Staphylococcus aures infections
    • R. P. Novick (ed.), VCH Publishers, Inc., New York, N.Y.
    • Foster, T. J., M. O'Reilly, P. Phonimdaeng, J. Cooney, A. H. Patel, and A. J. Bramley. 1990. Genetic studies of virulence factors of Stapliylococcus aureus: properties of coagulase, γ-toxin, α-toxin, β-toxin, and protein A in the pathogenesis of Staphylococcus aures infections, p. 403-417. In R. P. Novick (ed.), Molecular biology of the staphylococci, VCH Publishers, Inc., New York, N.Y.
    • (1990) Molecular Biology of the Staphylococci , pp. 403-417
    • Foster, T.J.1    O'Reilly, M.2    Phonimdaeng, P.3    Cooney, J.4    Patel, A.H.5    Bramley, A.J.6
  • 13
    • 0022628814 scopus 로고
    • Transposon mutagenesis as a tool to study the role of hemolysin in the virulence of Listeria monocytogenes
    • Gaillard, J. L., P. Berche, and P. Sansonetti. 1986. Transposon mutagenesis as a tool to study the role of hemolysin in the virulence of Listeria monocytogenes. Infect. Immun. 52:50-55.
    • (1986) Infect. Immun. , vol.52 , pp. 50-55
    • Gaillard, J.L.1    Berche, P.2    Sansonetti, P.3
  • 14
    • 0029080571 scopus 로고
    • Transcriptional analysis of rolling circle replicating plasmid pVT736-1: Evidence for replication control by antisense RNA
    • Galli, D. M., and D. J. LeBlanc. 1995. Transcriptional analysis of rolling circle replicating plasmid pVT736-1: evidence for replication control by antisense RNA. J. Bacteriol. 177:4474-4480.
    • (1995) J. Bacteriol. , vol.177 , pp. 4474-4480
    • Galli, D.M.1    LeBlanc, D.J.2
  • 15
    • 0020959710 scopus 로고
    • Studies on the transformation of Escherichia coli with plasmids
    • Hanahan, D. 1983. Studies on the transformation of Escherichia coli with plasmids. J. Mol. Biol. 166:557-580.
    • (1983) J. Mol. Biol. , vol.166 , pp. 557-580
    • Hanahan, D.1
  • 16
    • 0028062148 scopus 로고
    • Control of oncogenc expression by antisense nucleic acids
    • Hélène, C. 1994. Control of oncogenc expression by antisense nucleic acids. Eur. J. Cancer 30A:1721-1726.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 1721-1726
    • Hélène, C.1
  • 17
    • 0020315189 scopus 로고
    • Nucleotide sequence and functional map of pE194, a plasmid that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibiotics
    • Horinouchi. S., and B. Weisblum. 1982. Nucleotide sequence and functional map of pE194, a plasmid that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibiotics. J. Bacteriol. 150:804-814.
    • (1982) J. Bacteriol. , vol.150 , pp. 804-814
    • Horinouchi, S.1    Weisblum, B.2
  • 18
    • 0021783046 scopus 로고
    • Genetic analysis of bacterial virulence determinants in Bordetella pertussis and the pathogenic Yersinia
    • Isberg, R. R., and S. Falkow. 1985. Genetic analysis of bacterial virulence determinants in Bordetella pertussis and the pathogenic Yersinia. Curr. Top. Microbiol. Immunol. 118:1-11.
    • (1985) Curr. Top. Microbiol. Immunol. , vol.118 , pp. 1-11
    • Isberg, R.R.1    Falkow, S.2
  • 19
    • 33845382806 scopus 로고
    • Non-parametric estimation from incomplete observations
    • Kaplan, E. L., and P. Meier. 1958. Non-parametric estimation from incomplete observations. J. Am. Stat. Assoc. 53:456-481.
    • (1958) J. Am. Stat. Assoc. , vol.53 , pp. 456-481
    • Kaplan, E.L.1    Meier, P.2
  • 20
    • 0020551054 scopus 로고
    • Cloning, expression, and mapping of the Staphylococcus aureus α-hemolysin determinant in Escherichia coli K-12
    • Kehoe, M., J. Duncan, T. Foster, N. Fairweather, and G. Dougan. 1983. Cloning, expression, and mapping of the Staphylococcus aureus α-hemolysin determinant in Escherichia coli K-12. Infect. Immun. 41:1105-1111.
    • (1983) Infect. Immun. , vol.41 , pp. 1105-1111
    • Kehoe, M.1    Duncan, J.2    Foster, T.3    Fairweather, N.4    Dougan, G.5
  • 21
    • 0025779401 scopus 로고
    • Construction of single-copy integration vectors for Staphylococcus aureus
    • Lee, C. Y., S. L. Buranen, and Z. H. Ye. 1991. Construction of single-copy integration vectors for Staphylococcus aureus. Gene 103:101-105.
    • (1991) Gene , vol.103 , pp. 101-105
    • Lee, C.Y.1    Buranen, S.L.2    Ye, Z.H.3
  • 22
    • 0026323938 scopus 로고
    • Site-specific integration of mycobacteriophage L5: Integration-proficient vectors for Mycobacterium smegmulis, Mycobacterium tuberculosis, and bacille Calmette-Guérin
    • Lee, M. H., L. Pascopella, W. R. Jacobs, Jr., and G. F. Hatfull. 1991. Site-specific integration of mycobacteriophage L5: integration-proficient vectors for Mycobacterium smegmulis, Mycobacterium tuberculosis, and bacille Calmette-Guérin. Proc. Natl. Acad. Sci. USA 88:3111-3115.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3111-3115
    • Lee, M.H.1    Pascopella, L.2    Jacobs Jr., W.R.3    Hatfull, G.F.4
  • 23
    • 0029074366 scopus 로고
    • Sequence specificity on the growth suppression and induction of apoptosis of chronic mycloid leukemia cells by BCR-ARL anti-sense oligode-oxynucleoside phosphorothioates
    • Maekawa, T., S. Kimura, K. Hirakawa, A. Murakami, G. Zon, and T. Abe. 1995. Sequence specificity on the growth suppression and induction of apoptosis of chronic mycloid leukemia cells by BCR-ARL anti-sense oligode-oxynucleoside phosphorothioates. Int. J. Cancer 62:63-69.
    • (1995) Int. J. Cancer , vol.62 , pp. 63-69
    • Maekawa, T.1    Kimura, S.2    Hirakawa, K.3    Murakami, A.4    Zon, G.5    Abe, T.6
  • 24
    • 0028216879 scopus 로고
    • Site-directed mutagenesis of the alpha-toxin gene ol Staphylococcus aureus: Role of histidines in toxin activity in vitro and in a murine model
    • Menzies, B. E., and D. S. Kernodle. 1994. Site-directed mutagenesis of the alpha-toxin gene ol Staphylococcus aureus: role of histidines in toxin activity in vitro and in a murine model. Infect. Immun. 62:1843-1847.
    • (1994) Infect. Immun. , vol.62 , pp. 1843-1847
    • Menzies, B.E.1    Kernodle, D.S.2
  • 25
    • 0029986936 scopus 로고    scopus 로고
    • Passive immunization with antiserum to a nonloxic alpha-toxin mutant from Staphylococcus aureus is protective in a murine model
    • Menzies, B. E., and D. S. Kernodle. 1996. Passive immunization with antiserum to a nonloxic alpha-toxin mutant from Staphylococcus aureus is protective in a murine model. Infect. Immun. 64:1839-1841.
    • (1996) Infect. Immun. , vol.64 , pp. 1839-1841
    • Menzies, B.E.1    Kernodle, D.S.2
  • 26
    • 0021240438 scopus 로고
    • Transposon-mediated mutagenesis and recombination in Vibrio cholerae
    • Newland, J. W., B. A. Green, and R. K. Holmes. 1984. Transposon-mediated mutagenesis and recombination in Vibrio cholerae. Infect. Immun. 45:428-432.
    • (1984) Infect. Immun. , vol.45 , pp. 428-432
    • Newland, J.W.1    Green, B.A.2    Holmes, R.K.3
  • 27
    • 0002794633 scopus 로고
    • The staphylococcus as a molecular genetic system
    • Iu R. P. Novick (ed.), VCH Publishers, Inc., New York. N.Y.
    • Novick, R. P. 1990. The staphylococcus as a molecular genetic system, p. 1-37. Iu R. P. Novick (ed.), Molecular biology of the staphylococci. VCH Publishers, Inc., New York. N.Y.
    • (1990) Molecular Biology of the Staphylococci , pp. 1-37
    • Novick, R.P.1
  • 28
    • 1842396267 scopus 로고
    • Transformation of bacterial protoplasts
    • O'Reilly, M., and T. J. Foster. 1988. Transformation of bacterial protoplasts. FEMS Symp. 40:203-204.
    • (1988) FEMS Symp. , vol.40 , pp. 203-204
    • O'Reilly, M.1    Foster, T.J.2
  • 29
    • 0023518575 scopus 로고
    • Virulence of protein A-deficient and alpha-toxin-deficient mutants of Staphylococcus aureus isolated by allele replacement
    • Patel, A. H., P. Nowlan, E. D. Weavers, and T. Foster. 1987. Virulence of protein A-deficient and alpha-toxin-deficient mutants of Staphylococcus aureus isolated by allele replacement. Infect. Immun. 55:3103-3110.
    • (1987) Infect. Immun. , vol.55 , pp. 3103-3110
    • Patel, A.H.1    Nowlan, P.2    Weavers, E.D.3    Foster, T.4
  • 30
    • 0027932230 scopus 로고
    • Antisense phosphorothioate oligonucleotides: Selective killing of the intracellular parasite Leislhmania amazonensis
    • Ramazeilles, C., R. K. Mishra, S. Moreau, E. Pascolo, and J.-J. Touliné. 1994. Antisense phosphorothioate oligonucleotides: selective killing of the intracellular parasite Leislhmania amazonensis. Proc. Natl. Acad. Sci. USA 91:7859-7863.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7859-7863
    • Ramazeilles, C.1    Mishra, R.K.2    Moreau, S.3    Pascolo, E.4    Touliné, J.-J.5
  • 31
    • 0028795127 scopus 로고
    • Transcriptional inhibition of the parvovirus minute virus of mice by constitutive expression of an antisense RNA targeted against the NS-1 transactivator protein
    • Ramírez, J. C., J. F. Santarén, and J. M. Almendral. 1995. Transcriptional inhibition of the parvovirus minute virus of mice by constitutive expression of an antisense RNA targeted against the NS-1 transactivator protein. Virology 206:57-68.
    • (1995) Virology , vol.206 , pp. 57-68
    • Ramírez, J.C.1    Santarén, J.F.2    Almendral, J.M.3
  • 33
    • 0028901802 scopus 로고
    • Therapeutic antisense and ribozymes
    • Rossi, J. J. 1995. Therapeutic antisense and ribozymes. Br. Med. Bull. 51: 217-225.
    • (1995) Br. Med. Bull. , vol.51 , pp. 217-225
    • Rossi, J.J.1
  • 36
    • 0027376439 scopus 로고
    • Antisense oligonucleotidces as therapeutic agents - Is the bullet realK magical?
    • Stein, C. A., and Y.-C. Cheng. 1993. Antisense oligonucleotidces as therapeutic agents - is the bullet realK magical? Science 261:1004-1012.
    • (1993) Science , vol.261 , pp. 1004-1012
    • Stein, C.A.1    Cheng, Y.-C.2
  • 37
    • 85041131924 scopus 로고
    • Antisense RNA control in bacteria, phages, and plasmids
    • Wagner, E. G, H., and R. W. Simons, 1994. Antisense RNA control in bacteria, phages, and plasmids. Annu. Rev Microbiol. 48:713-742.
    • (1994) Annu. Rev Microbiol. , vol.48 , pp. 713-742
    • Wagner, E.G.H.1    Simons, R.W.2
  • 38
    • 0011823131 scopus 로고
    • A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversion in mammalian cells and Xenopus eggs
    • Wagner, R. W., J. E. Smith, B. S. Cooperman, and K. Nishikura. 1989. A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversion in mammalian cells and Xenopus eggs. Proc. Natl. Acail. Sci. USA 86:2647-2651.
    • (1989) Proc. Natl. Acail. Sci. USA , vol.86 , pp. 2647-2651
    • Wagner, R.W.1    Smith, J.E.2    Cooperman, B.S.3    Nishikura, K.4
  • 39
    • 0029037812 scopus 로고
    • Antisense phosphorothioate oligode-oxynucletides alter HIV type 1 replication in cultured human macrophages and peripheral blood mononuclear cells
    • Weichold, F. F., J. Lisziewica, R. A. Zeman, L. S. Nerurkar, S. Agrawal, M. S. Reitz, Jr., and R. C. Gall. 1995. Antisense phosphorothioate oligode-oxynucletides alter HIV type 1 replication in cultured human macrophages and peripheral blood mononuclear cells. AIDS Res. Hum. Retroviruses 11:863-867.
    • (1995) AIDS Res. Hum. Retroviruses , vol.11 , pp. 863-867
    • Weichold, F.F.1    Lisziewica, J.2    Zeman, R.A.3    Nerurkar, L.S.4    Agrawal, S.5    Reitz Jr., M.S.6    Gall, R.C.7
  • 40
    • 0028086655 scopus 로고
    • Anisense treatment of viral infection
    • Whitton, J. L. 1994. Anisense treatment of viral infection. Adv. Virus Res. 44:267-303.
    • (1994) Adv. Virus Res. , vol.44 , pp. 267-303
    • Whitton, J.L.1
  • 41
    • 85045799616 scopus 로고
    • Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA
    • Zamecnik, P. C., J. Goodchild, Y. Taguchi, and P. S. Sarin. 1986. Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA. Proc. Natl. Acad. Sci. USA 84:7706-7710.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7706-7710
    • Zamecnik, P.C.1    Goodchild, J.2    Taguchi, Y.3    Sarin, P.S.4


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