SIRT1 deacetylates FOXA2 and is critical for Pdx1 transcription and β-cell formation

International Journal of Biological Sciences

Volumn 9, Issue 9, 2013, Pages 934-946

  Wang, Rui Hong ^a   Xu, Xiaoling ^a   Kim, Hyun Seok ^a   Xiao, Zhen ^b   Deng, Chu Xia ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

FOXA2; Insulin; PDX1; Sirt1

Indexed keywords

HOMEODOMAIN PROTEIN; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; SIRTUIN 1; TRANSACTIVATOR PROTEIN;

ACETYLATION; ARTICLE; CELL DIFFERENTIATION; CYTOLOGY; FOXA2; GENETICS; INSULIN.; METABOLISM; PANCREAS ISLET BETA CELL; PDX1; PHYSIOLOGY; SIRT1;

FOXA2; INSULIN.; PDX1; SIRT1;

ACETYLATION; CELL DIFFERENTIATION; HOMEODOMAIN PROTEINS; INSULIN-SECRETING CELLS; SIRTUIN 1; TRANS-ACTIVATORS;

EID: 84884581542     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.7529     Document Type: Article

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