A Pancreatic β-Cell-specific Enhancer in the Human PDX-1 Gene Is Regulated by Hepatocyte Nuclear Factor 3β (HNF-3β), HNF-1α, and SPs Transcription Factors

Journal of Biological Chemistry

Volumn 276, Issue 20, 2001, Pages 17533-17540

  Ben Shushan, Etti ^b   Marshak, Sonya ^b   Shoshkes, Michal ^b   Cerasi, Erol ^b   Melloul, Danielle ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYST ACTIVITY; CHEMICAL BONDS; CYTOLOGY; ENZYMES; MUTAGENESIS;

PANCREAS;

GENES;

DEOXYRIBONUCLEASE I; DNA; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 3; HEPATOCYTE NUCLEAR FACTOR 3BETA; NUCLEAR FACTOR I; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DRUG DERIVATIVE; FOXA2 PROTEIN, HUMAN; FOXA2 PROTEIN, MOUSE; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1BETA; HOMEODOMAIN PROTEIN; INSULIN PROMOTER FACTOR 1; LUCIFERASE; MITOPODOZIDE; NUCLEAR PROTEIN; PODOPHYLLIN; PODOPHYLLOTOXIN; RECOMBINANT PROTEIN; TCF1 PROTEIN, HUMAN; TCF1 PROTEIN, MOUSE; TCF2 PROTEIN, HUMAN; TCF2 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL CULTURE; CHO CELL; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE PREDISPOSITION; DNA BINDING; ENHANCER REGION; GENE; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PDX 1 GENE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; ANIMAL; CELL LINE; CELL STRAIN 3T3; CELL STRAIN COS1; CERCOPITHECUS; DNA FOOTPRINTING; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; METABOLISM; MOLECULAR GENETICS; PANCREAS ISLET;

ANIMALIA;

3T3 CELLS; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CERCOPITHECUS AETHIOPS; CHO CELLS; COS CELLS; CRICETINAE; DNA FOOTPRINTING; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; GENES, REPORTER; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HOMEODOMAIN PROTEINS; HUMANS; ISLETS OF LANGERHANS; LUCIFERASES; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PODOPHYLLIN; PODOPHYLLOTOXIN; RECOMBINANT PROTEINS; SEQUENCE DELETION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035907378     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009088200     Document Type: Article

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