SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice

Breast Cancer Research

Volumn 9, Issue 1, 2007, Pages

  Li, Hongzhe ^a   Rajendran, Grace K ^a   Liu, Ninning ^a   Ware, Carol ^a   Rubin, Brian P ^a,b   Gu, Yansong ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; HISTONE DEACETYLASE; I KAPPA B KINASE ALPHA; SIRTUIN 1; SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA; ESTROGEN INSULIN LIKE GROWTH FACTOR 1, MOUSE; ESTROGEN-INSULIN-LIKE GROWTH FACTOR-1, MOUSE; SIRT1 PROTEIN, MOUSE; SIRTUIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; BREAST DEVELOPMENT; BREAST EPITHELIUM; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; FERTILITY; GROWTH RETARDATION; LACTATION DISORDER; MALE; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SLOW RELEASE FORMULATION; ANIMAL; BREAST TUMOR; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; UDDER;

ANIMALS; BREAST NEOPLASMS; ESTROGENS; FEMALE; INSULIN-LIKE GROWTH FACTOR I; MAMMARY GLANDS, ANIMAL; MICE; SIGNAL TRANSDUCTION; SIRTUINS;

EID: 34248157332     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr1632     Document Type: Article

References (60)

1. Imai S Armstrong CM Kaeberlein M Guarente L Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase Nature 2000, 403:795-800. 10.1038/35001622 10693811
2. Landry J Sutton A Tafrov ST Heller RC Stebbins J Pillus L Sternglanz R The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases Proc Natl Acad Sci USA 2000, 97:5807-5811. 18515 10811920 10.1073/pnas.110148297
3. Aparicio OM Billington BL Gottschling DE Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae Cell 1991, 66:1279-1287. 10.1016/0092-8674(91)90049-5 1913809
4. Grunstein M Molecular model for telomeric heterochromatin in yeast Curr Opin Cell Biol 1997, 9:383-387. 10.1016/S0955-0674(97)80011-7 9159071
5. Lin SJ Defossez PA Guarente L Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae Science 2000, 289:2126-2128. 10.1126/science.289.5487.2126 11000115
6. Tissenbaum HA Guarente L Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans Nature 2001, 410:227-230. 10.1038/ 35065638 11242085
7. Fabrizio P Gattazzo C Battistella L Wei M Cheng C McGrew K Longo VD Sir2 blocks extreme life-span extension Cell 2005, 123:655-667. 10.1016/ j.cell.2005.08.042 16286010
8. Kenyon C The plasticity of aging: Insights from long-lived mutants Cell 2005, 120:449-460. 10.1016/j.cell.2005.02.002 15734678
9. Katic M Kahn CR The role of insulin and IGF-1 signaling in longevity Cell Mol Life Sci 2005, 62:320-343. 10.1007/s00018-004-4297-y 15723168
10. Brunet A Sweeney LB Sturgill JF Chua KF Greer PL Lin Y Tran H Ross SE Mostoslavsky R Cohen HY Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science 2004, 303:2011-2015. 10.1126/science.1094637 14976264
11. Motta MC Divecha N Lemieux M Kamel C Chen D Gu W Bultsma Y McBurney M Guarente L Mammalian SIRT1 represses forkhead transcription factors Cell 2004, 116:551-563. 10.1016/S0092-8674(04)00126-6 14980222
12. Daitoku H Hatta M Matsuzaki H Aratani S Ohshima T Miyagishi M Nakajima T Fukamizu A Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity Proc Natl Acad Sci USA 2004, 101:10042-10047. 454161 15220471 10.1073/pnas.0400593101
13. Datta SR Brunet A Greenberg ME Cellular survival: A play in three Akts Genes Dev 1999, 13:2905-2927. 10.1101/gad.13.22.2905 10579998
14. Guarente L Picard F Calorie restriction - the SIR2 connection Cell 2005, 120:473-482. 10.1016/j.cell.2005.01.029 15734680
15. Baker ME Steroid receptor phylogeny and vertebrate origins Mol Cell Endocrinol 1997, 135:101-107. 10.1016/S0303-7207(97)00207-4
16. Wood TL Richert MM Stull MA Allar MA The insulin-like growth factors (IGFs) and IGF binding proteins in postnatal development of murine mammary glands J Mammary Gland Biol Neoplasia 2000, 5:31-42. 10.1023/ A:1009511131541 10791766
17. Hovey RC Trott JF Vonderhaar BK Establishing a framework for the functional mammary gland: From endocrinology to morphology J Mammary Gland Biol Neoplasia 2002, 7:17-38. 10.1023/A:1015766322258 12160083
18. Luo J Nikolaev AY Imai S Chen D Su F Shiloh A Guarente L Gu W Negative control of p53 by Sir2alpha promotes cell survival under stress Cell 2001, 107:137-148. 10.1016/S0092-8674(01)00524-4 11672522
19. Vaziri H Dessain SK Ng Eaton E Imai SI Frye RA Pandita TK Guarente L Weinberg RA hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase Cell 2001, 107:149-159. 10.1016/S0092-8674(01)00527-X 11672523
20. Yeung F Hoberg JE Ramsey CS Keller MD Jones DR Frye RA Mayo MW Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase EMBO J 2004, 23:2369-2380. 423286 15152190 10.1038/ sj.emboj.7600244
21. Rodgers JT Lerin C Haas W Gygi SP Spiegelman BM Puigserver P Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1 Nature 2005, 434:113-118. 10.1038/nature03354 15744310
22. McBurney MW Yang X Jardine K Hixon M Boekelheide K Webb JR Lansdorp PM Lemieux M The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis Mol Cell Biol 2003, 23:38-54. 140671 12482959 10.1128/ MCB.23.1.38-54.2003
23. Cheng HL Mostoslavsky R Saito S Manis JP Gu Y Patel P Bronson R Appella E Alt FW Chua KF Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice Proc Natl Acad Sci USA 2003, 100:10794-10799. 196882 12960381 10.1073/pnas.1934713100
24. Silberstein GB Postnatal mammary gland morphogenesis Microsc Res Tech 2001, 52:155-162. 10.1002/ 1097-0029(20010115)52:2<155::AID-JEMT1001>3.0.CO;2-P 11169863
25. Parmar H Cunha GR Epithelial-stromal interactions in the mouse and human mammary gland in vivo Endocr Relat Cancer 2004, 11:437-458. 10.1677/ erc.1.00659 15369447
26. Richards RG Klotz DM Walker MP Diaugustine RP Mammary gland branching morphogenesis is diminished in mice with a deficiency of insulin-like growth factor-I (IGF-I), but not in mice with a liver-specific deletion of IGF-I Endocrinology 2004, 145:3106-3110. 10.1210/en.2003-1112 15059953
27. Mueller SO Clark JA Myers PH Korach KS Mammary gland development in adult mice requires epithelial and stromal estrogen receptor alpha Endocrinology 2002, 143:2357-2365. 10.1210/en.143.6.2357 12021201
28. Baker J Hardy MP Zhou J Bondy C Lupu F Bellve AR Efstratiadis A Effects of an Igf1 gene null mutation on mouse reproduction Mol Endocrinol 1996, 10:903-918. 10.1210/me.10.7.903 8813730
29. Kleinberg DL Early mammary development: Growth hormone and IGF-1 J Mammary Gland Biol Neoplasia 1997, 2:49-57. 10.1023/A:1026373513521 10887519
30. Walden PD Ruan W Feldman M Kleinberg DL Evidence that the mammary fat pad mediates the action of growth hormone in mammary gland development Endocrinology 1998, 139:659-662. 10.1210/en.139.2.659 9449638
31. Ruan W Kleinberg DL Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development Endocrinology 1999, 140:5075-5081. 10.1210/en.140.11.5075 10537134
32. Tsukamoto Y Kato J Ikeda H Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae Nature 1997, 388:900-903. 10.1038/42288 9278054
33. Mills KD Sinclair DA Guarente L MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks Cell 1999, 97:609-620. 10.1016/S0092-8674(00)80772-2 10367890
34. Mostoslavsky R Chua KF Lombard DB Pang WW Fischer MR Gellon L Liu P Mostoslavsky G Franco S Murphy MM Genomic instability and aging-like phenotype in the absence of mammalian SIRT6 Cell 2006, 124:315-329. 10.1016/j.cell.2005.11.044 16439206
35. Gu Y Seidl KJ Rathbun GA Zhu C Manis JP van der Stoep N Davidson L Cheng HL Sekiguchi JM Frank K Growth retardation and leaky SCID phenotype of Ku70-deficient mice Immunity 1997, 7:653-665. 10.1016/ S1074-7613(00)80386-6 9390689
36. Borghesani PR Alt FW Bottaro A Davidson L Aksoy S Rathbun GA Roberts TM Swat W Segal RA Gu Y Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice Proc Natl Acad Sci USA 2000, 97:3336-3341. 16240 10716718 10.1073/pnas.050584897
37. 1 expression during mammary gland development Cell 2001, 107:763-775. 10.1016/S0092-8674(01)00599-2 11747812
38. Clarkson RW Heeley JL Chapman R Aillet F Hay RT Wyllie A Watson CJ NF-κB inhibits apoptosis in murine mammary epithelia J Biol Chem 2000, 275:12737-12742. 10.1074/jbc.275.17.12737 10777569
39. Geymayer S Doppler W Activation of NF-kappaB p50/p65 is regulated in the developing mammary gland and inhibits STAT5-mediated beta-casein gene expression FASEB J 2000, 14:1159-1170. 10834938
40. Murphy LJ Overexpression of insulin-like growth factor binding protein-1 in transgenic mice Pediatr Nephrol 2000, 14:567-571. 10.1007/ s004670000347 10912520
41. Hoffmann A Levchenko A Scott ML Baltimore D The IkapppaB-NF-kappaB signalling module:tEmporal control and selective gene activation Science 2002, 298:1241-1245. 10.1126/science.1071914 12424381
42. Covert MW Leung TH Gaston JE Baltimore D Achieving stability of lipopolysaccharide-induced NF-kappaB activation Science 2005, 309:1854-1857. 10.1126/science.1112304 16166516
43. Werner SL Barken D Hoffmann A Stimulus specificity of gene expression programs determined by temporal control of IKK activity Science 2005, 309:1857-1861. 10.1126/science.1113319 16166517
44. Liu JP Baker J Perkins AS Robertson EJ Efstratiadis A Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) Cell 1993, 75:59-72. 8402901
45. Powell-Braxton L Hollingshead P Warburton C Dowd M Pitts-Meek S Dalton D Gillett N Stewart TA IGF-I is required for normal embryonic growth in mice Genes Dev 1993, 7:2609-2617. 8276243
46. Peng XD Xu PZ Chen ML Hahn-Windgassen A Skeen J Jacobs J Sundararajan D Chen WS Crawford SE Coleman KG Hay N Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2 Genes Dev 2003, 17:1352-1365. 196068 12782654 10.1101/gad.1089403
47. Castrillon DH Miao L Kollipara R Horner JW DePinho RA Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a Science 2003, 301:215-218. 10.1126/science.1086336 12855809
48. Unterman TG Glick RP Waites GT Bell SC Production of insulin-like growth factor-binding proteins by human central nervous system tumors Cancer Res 1991, 51:3030-3036. 1709588
49. Schneider MR Lahm H Wu M Hoeflich A Wolf E Transgenic mouse models for studying the functions of insulin-like growth factor-binding proteins FASEB J 2000, 14:629-640. 10744620
50. Guo S Rena G Cichy S He X Cohen P Unterman T Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence J Biol Chem 1999, 274:17184-17192. 10.1074/jbc.274.24.17184 10358076
51. Tang ED Nunez G Barr FG Guan KL Negative regulation of the forkhead transcription factor FKHR by Akt J Biol Chem 1999, 274:16741-16746. 10.1074/jbc.274.24.16741 10358014
52. Durham SK Suwanichkul A Scheimann AO Yee D Jackson JG Barr FG Powell DR FKHR binds the insulin response element in the insulin-like growth factor binding protein-1 promoter Endocrinology 1999, 140:3140-3146. 10.1210/en.140.7.3140 10385407
53. Hewitt SC Korach KS Progesterone action and responses in the alphaERKO mouse Steroids 2000, 65:551-557. 10.1016/S0039-128X(00)00113-6 11108859
54. Goswami D Conway GS Premature ovarian failure Hum Reprod Update 2005, 11:391-410. 10.1093/humupd/dmi012 15919682
55. Hens JR Wysolmerski JJ Key stages of mammary gland development: molecular mechanisms involved in the formation of the embryonic mammary gland Breast Cancer Res 2005, 7:220-224. 1242158 16168142 10.1186/bcr1306
56. Mallepell S Krust A Chambon P Brisken C Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland Proc Natl Acad Sci USA 2006, 103:2196 -2201. 1413744 16452162 10.1073/pnas.0510974103
57. Nemoto S Fergusson MM Finkel T Nutrient availability regulates SIRT1 through a forkhead-dependent pathway Science 2004, 306:2105-2108. 10.1126/science.1101731 15604409
58. van Noord PA Breast cancer and the brain: A neurodevelopmental hypothesis to explain the opposing effects of caloric deprivation during the Dutch famine of 1944-1945 on breast cancer and its risk factors J Nutr 2004, 134:3399S-3406S. 15570045
59. de Boer VC de Goffau MC Arts IC Hollman PC Keijer J SIRT1 stimulation by polyphenols is affected by their stability and metabolism Mech Ageing Dev 2006, 127:618-627. 10.1016/j.mad.2006.02.007 16603228
60. Heltweg B Gatbonton T Schuler AD Posakony J Li H Goehle S Kollipara R Depinho RA Gu Y Simon JA Bedalov A Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes Cancer Res 2006, 66:4368-4377. 10.1158/0008-5472.CAN-05-3617 16618762