ß1 Integrin Binding Phosphorylates Ezrin at T567 to Activate a Lipid Raft Signalsome Driving Invadopodia Activity and Invasion

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Antelmi, Ester ^a,b   Cardone, Rosa A ^a   Greco, Maria R ^a   Rubino, Rosa ^a   Di Sole, Francesca ^c   Martino, Nicola A ^a   Casavola, Valeria ^a   Carcangiu, MariaLuisa ^b   Moro, Loredana ^d   Reshkin, Stephan J ^a  

^a UNIVERSITY OF BARI   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EZRIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; SODIUM PROTON EXCHANGE PROTEIN 1; THREONINE;

ADULT; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INVADOPODIA; LIPID RAFT; MAJOR CLINICAL STUDY; METASTASIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TUMOR INVASION;

ANALYSIS OF VARIANCE; ANTIGENS, CD29; BREAST NEOPLASMS; CYTOSKELETAL PROTEINS; DNA PRIMERS; EXTRACELLULAR MATRIX; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; ITALY; MEMBRANE MICRODOMAINS; NEOPLASM INVASIVENESS; PHOSPHORYLATION; PSEUDOPODIA; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION;

EID: 84884565615     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075113     Document Type: Article

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