Ezrin is associated with gastric cancer progression and prognosis

Pathology and Oncology Research

Volumn 17, Issue 4, 2011, Pages 909-915

  Li, Li ^a   Wang, Yuan Yu ^a   Zhao, Zhong Sheng ^a   Ma, Jie ^a  

^a ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Ezrin; Gastric carcinoma; Prognosis; Progression

Indexed keywords

EZRIN;

ADULT; AGE; AGED; ARTICLE; CANCER GROWTH; CANCER INVASION; CANCER LOCALIZATION; CANCER STAGING; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISTANT METASTASIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MALE; PROGNOSIS; PROTEIN EXPRESSION; STOMACH CANCER; SURVIVAL RATE; TUMOR VOLUME;

ADULT; AGED; AGED, 80 AND OVER; CYTOSKELETAL PROTEINS; DISEASE PROGRESSION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; STOMACH NEOPLASMS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84855446010     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-011-9402-y     Document Type: Article

References (20)

1. Zhan W-H, Han F-H (2008) Surgical therapy of gastric cancer in china. J Pract Oncol 23:91-93
2. Bretscher A, Edwards K, Fehonv RG (2002) ERM proteins and merlin: Integrators at the cell cortex. Nat Rev Mol Cell Biol 3:586-599
3. Gautreau A, Louvard D, Arpin M (2002) ERM proteins and NF2 tumor suppressor: The Yin and Yang of cortical actin or ganization and cell growth signaling. Curr Opin Cell Biol 14:104-109 (Pubitemid 34131663)
4. Saotome I, Curto M, McClatchey AI (2004) Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine. Dev Cell 6:855-864 (Pubitemid 38745419)
5. Srivastava J, Elliott BE, Louvard D, Arpin M (2005) Srcdependent ezrin phosphorylation in adhesion-mediated signaling. Mol Biol Cell 16:1481-1490 (Pubitemid 40349581)
6. Wei YC, Li CF, Yu SC, Chou FF, Fang FM, Eng HL, Uen YH, Tian YF, Wu JM, Li SH, Huang WW, Li WM, Huang HY (2009) Ezrin overexpression in gastrointestinal stromal tumors: An independent adverse prognosticator associated with the nongastric location. Mod Pathol 22(10):1351-1360
7. Zhai JW, Yang XG, Yang FS, Hu JG, Hua WX (2010) Expression and clinical significance of Ezrin and E-cadherin in esophageal squamous cell carcinoma. Chin J Cancer 29(3):317-320
8. Elzagheid A, Korkeila E, Bendardaf R, Buhmeida A, Heikkilä S, Vaheri A, Syrjänen K, Pyrhönen S, Carpén O (2008) Intense cytoplasmic ezrin immunoreactivity predicts poor survival in colorectal cancer. Hum Pathol 39(12):1737-1743
9. Valdman A, Fang X, Pang ST, Nilsson B, Ekman P, Egevad L (2005) Ezrin expression in prostate cancer and benign prostatic tissue. Eur Urol 48(5):852-857
10. Musial J, Sporny S, Nowicki A (2007) Prognostic significance of E-cadherin and ezrin immunohistochemical expression in prostate cancer. Pol J Pathol 58(4):235-243 (Pubitemid 351428300)
11. Bal N, Yildirim S, Nursal TZ, Bolat F, Kayaselcuk F (2007) Association of ezrin expression in intestinal and diffuse gastric carcinoma with clinicopathological parameters and tumor type. World J Gastroenterol 13(27):3726-3729 (Pubitemid 47202171)
12. Lee HS, Lee HK, Kim HS et al (2003) Tumour suppressor gene expression correlates with gastric cancer prognosis. J Pathol 200:39-46 (Pubitemid 36592634)
13. Zhang D, Salto-Tellez M, Putti TC et al (2003) Reliability of tissue microarrays in detecting protein expression and gene amplification in breast cancer. Mod Pathol 16:79-84 (Pubitemid 36152690)
14. Lee HS, Cho SB, Lee HE et al (2007) Protein expression profiling and molecular classification of gastric cancer by the tissue array method. Clin Cancer Res 13(14):4154-4163
15. Song LB, Liao WT, Mai HQ et al (2006) The clinical significance of twist expression in nasopharyngeal carcinoma. Cancer Lett 242:258-265
16. Fukuoka J, Fujii T, Shih JH et al (2004) Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer. Clin Cancer Res 10:4314-4324 (Pubitemid 38878869)
17. Hundahl SA, Phillips JL, Menck HR (2000) The National Cancer Data Base Report on poor survival of U.S. gastric carcinoma patients treated with gastrectomy: Fifth edition American Joint Committee on cancer staging, proximal disease, and the 'different disease' hypothesis. Cancer 88:921-932 (Pubitemid 30091113)
18. Wang HJ, Zhu JS, Zhang Q, Guo H, Dai YH, Xiong XP (2009) RNAi-mediated silencing of ezrin gene reverses malignant behavior of human gastric cancer cell line SGC-7901. J Dig Dis 10(4):258-264
19. Meng Y, Lu Z, Yu S, Zhang Q, Ma Y, Chen J (2010) Ezrin promotes invasion and metastasis of pancreatic cancer cells. J Transl Med 8:61
20. Chuan YC, Iglesias-Gato D, Fernandez-Perez L, Cedazo-Minguez A, Pang ST, Norstedt G, Pousette A, Flores-Morales A (2010) Ezrin mediates c-Myc actions in prostate cancer cell invasion. Oncogene 29(10):1531-1542