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Volumn 378, Issue 1-2, 2013, Pages 29-40

The role of angiotensin II in nonalcoholic steatohepatitis

Author keywords

Angiotensin II; Fibrosis; Mitochondria; NAFLD; Steatosis

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOPHEROL DERIVATIVE; ANGIOTENSIN II; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 6; LIPID; MITOCHONDRIAL DNA; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TEMPOL; TUMOR NECROSIS FACTOR ALPHA; VERY LOW DENSITY LIPOPROTEIN;

EID: 84884535307     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.04.013     Document Type: Review
Times cited : (59)

References (164)
  • 3
    • 0035131190 scopus 로고    scopus 로고
    • Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation (correction of activation) in the liver
    • Alonzi T., Maritano D., Gorgoni B., Rizzuto G., Libert C., Poli V. Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation (correction of activation) in the liver. Mol. Cell. Biol. 2001, 21:1621-1632.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1621-1632
    • Alonzi, T.1    Maritano, D.2    Gorgoni, B.3    Rizzuto, G.4    Libert, C.5    Poli, V.6
  • 5
    • 79953880237 scopus 로고    scopus 로고
    • Statin-based treatment for cardiovascular risk and non-alcoholic fatty liver disease. Killing two birds with one stone?
    • Athyros V.G., Tziomalos K., Daskalopoulos G.N., Karagiannis A., Mikhailidis D.P. Statin-based treatment for cardiovascular risk and non-alcoholic fatty liver disease. Killing two birds with one stone?. Ann. Med. 2011, 43:167-171.
    • (2011) Ann. Med. , vol.43 , pp. 167-171
    • Athyros, V.G.1    Tziomalos, K.2    Daskalopoulos, G.N.3    Karagiannis, A.4    Mikhailidis, D.P.5
  • 6
    • 33750999057 scopus 로고    scopus 로고
    • Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults randomized to receive 3 different classes of antihypertensive treatment: a report from the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)
    • Barzilay J.I., Davis B.R., Cutler J.A., Pressel S.L., Whelton P.K., Basile J., Margolis K.L., Ong S.T., Sadler L.S., Summerson J. Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults randomized to receive 3 different classes of antihypertensive treatment: a report from the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). Arch. Intern. Med. 2006, 166:2191-2201.
    • (2006) Arch. Intern. Med. , vol.166 , pp. 2191-2201
    • Barzilay, J.I.1    Davis, B.R.2    Cutler, J.A.3    Pressel, S.L.4    Whelton, P.K.5    Basile, J.6    Margolis, K.L.7    Ong, S.T.8    Sadler, L.S.9    Summerson, J.10
  • 11
    • 21344449292 scopus 로고    scopus 로고
    • Prevalence of and risk factors for nonalcoholic fatty liver disease: the dionysos nutrition and liver study
    • Bedogni G., Miglioli L., Masutti F., Tiribelli C., Marchesini G., Bellentani S. Prevalence of and risk factors for nonalcoholic fatty liver disease: the dionysos nutrition and liver study. Hepatology 2005, 42:44-52.
    • (2005) Hepatology , vol.42 , pp. 44-52
    • Bedogni, G.1    Miglioli, L.2    Masutti, F.3    Tiribelli, C.4    Marchesini, G.5    Bellentani, S.6
  • 12
    • 32844458032 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it
    • Begriche K., Igoudjil A., Pessayre D., Fromenty B. Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it. Mitochondrion 2006, 6:1-28.
    • (2006) Mitochondrion , vol.6 , pp. 1-28
    • Begriche, K.1    Igoudjil, A.2    Pessayre, D.3    Fromenty, B.4
  • 14
    • 50449086746 scopus 로고    scopus 로고
    • Obesity and free fatty acids
    • viii-ix
    • Boden G. Obesity and free fatty acids. Endocrinol. Metab. Clin. North Am. 2008, 37:635-646. viii-ix.
    • (2008) Endocrinol. Metab. Clin. North Am. , vol.37 , pp. 635-646
    • Boden, G.1
  • 15
    • 0015882341 scopus 로고
    • The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
    • Boveris A., Chance B. The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem. J. 1973, 134:707-716.
    • (1973) Biochem. J. , vol.134 , pp. 707-716
    • Boveris, A.1    Chance, B.2
  • 17
    • 77951674573 scopus 로고    scopus 로고
    • The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation
    • Brasier A.R. The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation. Cardiovasc. Res. 2010, 86:211-218.
    • (2010) Cardiovasc. Res. , vol.86 , pp. 211-218
    • Brasier, A.R.1
  • 18
    • 0038506851 scopus 로고    scopus 로고
    • The renin-angiotensin-aldosterone system: cardiorenal effects and implications for renal and cardiovascular disease states
    • Brewster U.C., Setaro J.F., Perazella M.A. The renin-angiotensin-aldosterone system: cardiorenal effects and implications for renal and cardiovascular disease states. Am. J. Med. Sci. 2003, 326:15-24.
    • (2003) Am. J. Med. Sci. , vol.326 , pp. 15-24
    • Brewster, U.C.1    Setaro, J.F.2    Perazella, M.A.3
  • 20
    • 79957899628 scopus 로고    scopus 로고
    • Mechanisms for the anti-inflammatory effects of statins
    • Bu D.X., Griffin G., Lichtman A.H. Mechanisms for the anti-inflammatory effects of statins. Curr. Opin. Lipidol. 2011, 22:165-170.
    • (2011) Curr. Opin. Lipidol. , vol.22 , pp. 165-170
    • Bu, D.X.1    Griffin, G.2    Lichtman, A.H.3
  • 21
    • 30944455145 scopus 로고    scopus 로고
    • Insulin resistance: a metabolic pathway to chronic liver disease
    • Bugianesi E., McCullough A.J., Marchesini G. Insulin resistance: a metabolic pathway to chronic liver disease. Hepatology 2005, 42:987-1000.
    • (2005) Hepatology , vol.42 , pp. 987-1000
    • Bugianesi, E.1    McCullough, A.J.2    Marchesini, G.3
  • 22
    • 48449106424 scopus 로고    scopus 로고
    • Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan
    • Clemenz M., Frost N., Schupp M., Caron S., Foryst-Ludwig A., Bohm C., Hartge M., Gust R., Staels B., Unger T., Kintscher U. Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan. Diabetes 2008, 57:1405-1413.
    • (2008) Diabetes , vol.57 , pp. 1405-1413
    • Clemenz, M.1    Frost, N.2    Schupp, M.3    Caron, S.4    Foryst-Ludwig, A.5    Bohm, C.6    Hartge, M.7    Gust, R.8    Staels, B.9    Unger, T.10    Kintscher, U.11
  • 23
    • 79959517565 scopus 로고    scopus 로고
    • Human fatty liver disease: old questions and new insights
    • Cohen J.C., Horton J.D., Hobbs H.H. Human fatty liver disease: old questions and new insights. Science 2011, 332:1519-1523.
    • (2011) Science , vol.332 , pp. 1519-1523
    • Cohen, J.C.1    Horton, J.D.2    Hobbs, H.H.3
  • 26
    • 53049097540 scopus 로고    scopus 로고
    • Renin-angiotensin system inhibitors protect against age-related changes in rat liver mitochondrial DNA content and gene expression
    • de Cavanagh E.M., Flores I., Ferder M., Inserra F., Ferder L. Renin-angiotensin system inhibitors protect against age-related changes in rat liver mitochondrial DNA content and gene expression. Exp. Gerontol. 2008, 43:919-928.
    • (2008) Exp. Gerontol. , vol.43 , pp. 919-928
    • de Cavanagh, E.M.1    Flores, I.2    Ferder, M.3    Inserra, F.4    Ferder, L.5
  • 28
    • 33745739887 scopus 로고    scopus 로고
    • NADPH oxidase in the liver: defensive, offensive, or fibrogenic?
    • De Minicis S., Bataller R., Brenner D.A. NADPH oxidase in the liver: defensive, offensive, or fibrogenic?. Gastroenterology 2006, 131:272-275.
    • (2006) Gastroenterology , vol.131 , pp. 272-275
    • De Minicis, S.1    Bataller, R.2    Brenner, D.A.3
  • 29
    • 58149380810 scopus 로고    scopus 로고
    • Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells
    • De Minicis S., Seki E., Oesterreicher C., Schnabl B., Schwabe R.F., Brenner D.A. Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells. Hepatology 2008, 48:2016-2026.
    • (2008) Hepatology , vol.48 , pp. 2016-2026
    • De Minicis, S.1    Seki, E.2    Oesterreicher, C.3    Schnabl, B.4    Schwabe, R.F.5    Brenner, D.A.6
  • 31
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly K.L., Smith C.I., Schwarzenberg S.J., Jessurun J., Boldt M.D., Parks E.J. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 2005, 115:1343-1351.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 32
    • 41949104144 scopus 로고    scopus 로고
    • Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction
    • Doughan A.K., Harrison D.G., Dikalov S.I. Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ. Res. 2008, 102:488-496.
    • (2008) Circ. Res. , vol.102 , pp. 488-496
    • Doughan, A.K.1    Harrison, D.G.2    Dikalov, S.I.3
  • 33
    • 34548234414 scopus 로고    scopus 로고
    • NASH and thiazolidinediones: not to be taken lightly
    • Dufour J.F. NASH and thiazolidinediones: not to be taken lightly. J. Hepatol. 2007, 47:451-453.
    • (2007) J. Hepatol. , vol.47 , pp. 451-453
    • Dufour, J.F.1
  • 34
    • 0036154857 scopus 로고    scopus 로고
    • Control of mitochondrial beta-oxidation flux
    • Eaton S. Control of mitochondrial beta-oxidation flux. Prog. Lipid Res. 2002, 41:197-239.
    • (2002) Prog. Lipid Res. , vol.41 , pp. 197-239
    • Eaton, S.1
  • 35
    • 77953545296 scopus 로고    scopus 로고
    • Central adiposity, systemic inflammation, and the metabolic syndrome
    • Elks C.M., Francis J. Central adiposity, systemic inflammation, and the metabolic syndrome. Curr. Hypertens. Rep. 2010, 12:99-104.
    • (2010) Curr. Hypertens. Rep. , vol.12 , pp. 99-104
    • Elks, C.M.1    Francis, J.2
  • 37
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: from steatosis to cirrhosis
    • Farrell G.C., Larter C.Z. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006, 43:S99-S112.
    • (2006) Hepatology , vol.43
    • Farrell, G.C.1    Larter, C.Z.2
  • 39
    • 0027320816 scopus 로고
    • Effects of angiotensin-converting enzyme inhibition on mitochondrial number in the aging mouse
    • Ferder L., Inserra F., Romano L., Ercole L., Pszenny V. Effects of angiotensin-converting enzyme inhibition on mitochondrial number in the aging mouse. Am. J. Physiol. 1993, 265:C15-C18.
    • (1993) Am. J. Physiol. , vol.265
    • Ferder, L.1    Inserra, F.2    Romano, L.3    Ercole, L.4    Pszenny, V.5
  • 40
    • 34548639473 scopus 로고    scopus 로고
    • Obesity-induced inflammation: a metabolic dialogue in the language of inflammation
    • Ferrante A.W. Obesity-induced inflammation: a metabolic dialogue in the language of inflammation. J. Intern. Med. 2007, 262:408-414.
    • (2007) J. Intern. Med. , vol.262 , pp. 408-414
    • Ferrante, A.W.1
  • 42
    • 74549140993 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults, 1999-2008
    • Flegal K.M., Carroll M.D., Ogden C.L., Curtin L.R. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010, 303:235-241.
    • (2010) JAMA , vol.303 , pp. 235-241
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Curtin, L.R.4
  • 43
    • 33745212477 scopus 로고    scopus 로고
    • Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance
    • Flowers M.T., Miyazaki M., Liu X., Ntambi J.M. Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance. J. Clin. Invest. 2006, 116:1478-1481.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1478-1481
    • Flowers, M.T.1    Miyazaki, M.2    Liu, X.3    Ntambi, J.M.4
  • 44
    • 84855883859 scopus 로고    scopus 로고
    • Effects of losartan and amlodipine alone or combined with simvastatin in hypertensive patients with nonalcoholic hepatic steatosis
    • Fogari R., Maffioli P., Mugellini A., Zoppi A., Lazzari P., Derosa G. Effects of losartan and amlodipine alone or combined with simvastatin in hypertensive patients with nonalcoholic hepatic steatosis. Eur J Gastroenterol Hepatol. 2012, 24:164-171.
    • (2012) Eur J Gastroenterol Hepatol. , vol.24 , pp. 164-171
    • Fogari, R.1    Maffioli, P.2    Mugellini, A.3    Zoppi, A.4    Lazzari, P.5    Derosa, G.6
  • 45
    • 7044264899 scopus 로고    scopus 로고
    • Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease
    • Gao D., Wei C., Chen L., Huang J., Yang S., Diehl A.M. Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 287:G1070-G1077.
    • (2004) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.287
    • Gao, D.1    Wei, C.2    Chen, L.3    Huang, J.4    Yang, S.5    Diehl, A.M.6
  • 46
    • 77956921023 scopus 로고    scopus 로고
    • The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways
    • Gao D., Nong S., Huang X., Lu Y., Zhao H., Lin Y., Man Y., Wang S., Yang J., Li J. The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways. J. Biol. Chem. 2010, 285:29965-29973.
    • (2010) J. Biol. Chem. , vol.285 , pp. 29965-29973
    • Gao, D.1    Nong, S.2    Huang, X.3    Lu, Y.4    Zhao, H.5    Lin, Y.6    Man, Y.7    Wang, S.8    Yang, J.9    Li, J.10
  • 47
    • 62949101948 scopus 로고    scopus 로고
    • NADPH oxidases and angiotensin II receptor signaling
    • Garrido A.M., Griendling K.K. NADPH oxidases and angiotensin II receptor signaling. Mol. Cell. Endocrinol. 2009, 302:148-158.
    • (2009) Mol. Cell. Endocrinol. , vol.302 , pp. 148-158
    • Garrido, A.M.1    Griendling, K.K.2
  • 48
    • 66549124116 scopus 로고    scopus 로고
    • Angiotensin receptor blockers in the treatment of NASH/NAFLD: could they be a first-class option?
    • Georgescu E.F. Angiotensin receptor blockers in the treatment of NASH/NAFLD: could they be a first-class option?. Adv. Ther. 2008, 25:1141-1174.
    • (2008) Adv. Ther. , vol.25 , pp. 1141-1174
    • Georgescu, E.F.1
  • 49
    • 65649112801 scopus 로고    scopus 로고
    • Angiotensin-receptor blockers as therapy for mild-to-moderate hypertension-associated non-alcoholic steatohepatitis
    • Georgescu E.F., Ionescu R., Niculescu M., Mogoanta L., Vancica L. Angiotensin-receptor blockers as therapy for mild-to-moderate hypertension-associated non-alcoholic steatohepatitis. World J. Gastroenterol. 2009, 15:942-954.
    • (2009) World J. Gastroenterol. , vol.15 , pp. 942-954
    • Georgescu, E.F.1    Ionescu, R.2    Niculescu, M.3    Mogoanta, L.4    Vancica, L.5
  • 52
    • 33745212925 scopus 로고    scopus 로고
    • Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance
    • Gutierrez-Juarez R., Pocai A., Mulas C., Ono H., Bhanot S., Monia B.P., Rossetti L. Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance. J. Clin. Invest. 2006, 116:1686-1695.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1686-1695
    • Gutierrez-Juarez, R.1    Pocai, A.2    Mulas, C.3    Ono, H.4    Bhanot, S.5    Monia, B.P.6    Rossetti, L.7
  • 53
    • 0036783050 scopus 로고    scopus 로고
    • The metabolic abnormalities associated with non-alcoholic fatty liver disease
    • Haque M., Sanyal A.J. The metabolic abnormalities associated with non-alcoholic fatty liver disease. Best Pract. Res. Clin. Gastroenterol. 2002, 16:709-731.
    • (2002) Best Pract. Res. Clin. Gastroenterol. , vol.16 , pp. 709-731
    • Haque, M.1    Sanyal, A.J.2
  • 54
    • 80255126307 scopus 로고    scopus 로고
    • Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue
    • Harford K.A., Reynolds C.M., McGillicuddy F.C., Roche H.M. Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue. Proc. Nutr. Soc. 2011, 70:408-417.
    • (2011) Proc. Nutr. Soc. , vol.70 , pp. 408-417
    • Harford, K.A.1    Reynolds, C.M.2    McGillicuddy, F.C.3    Roche, H.M.4
  • 56
    • 79955575806 scopus 로고    scopus 로고
    • Non-pharmacological aspects of blood pressure management: what are the data?
    • Hedayati S.S., Elsayed E.F., Reilly R.F. Non-pharmacological aspects of blood pressure management: what are the data?. Kidney Int. 2011, 79:1061-1070.
    • (2011) Kidney Int. , vol.79 , pp. 1061-1070
    • Hedayati, S.S.1    Elsayed, E.F.2    Reilly, R.F.3
  • 57
    • 34548452026 scopus 로고    scopus 로고
    • Improvement of insulin sensitivity by antagonism of the renin-angiotensin system
    • Henriksen E.J. Improvement of insulin sensitivity by antagonism of the renin-angiotensin system. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293:R974-R980.
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.293
    • Henriksen, E.J.1
  • 58
    • 0035724736 scopus 로고    scopus 로고
    • Selective angiotensin II receptor receptor antagonism reduces insulin resistance in obese Zucker rats
    • Henriksen E.J., Jacob S., Kinnick T.R., Teachey M.K., Krekler M. Selective angiotensin II receptor receptor antagonism reduces insulin resistance in obese Zucker rats. Hypertension 2001, 38:884-890.
    • (2001) Hypertension , vol.38 , pp. 884-890
    • Henriksen, E.J.1    Jacob, S.2    Kinnick, T.R.3    Teachey, M.K.4    Krekler, M.5
  • 60
    • 0942268772 scopus 로고    scopus 로고
    • Insulin resistance and ferritin as major determinants of nonalcoholic fatty liver disease in apparently healthy obese patients
    • Hsiao T.J., Chen J.C., Wang J.D. Insulin resistance and ferritin as major determinants of nonalcoholic fatty liver disease in apparently healthy obese patients. Int. J. Obes. Relat. Metab. Disord. 2004, 28:167-172.
    • (2004) Int. J. Obes. Relat. Metab. Disord. , vol.28 , pp. 167-172
    • Hsiao, T.J.1    Chen, J.C.2    Wang, J.D.3
  • 61
    • 79953697675 scopus 로고    scopus 로고
    • Renin-angiotensin-aldosterone system in diabetes and hypertension
    • Hsueh W.A., Wyne K. Renin-angiotensin-aldosterone system in diabetes and hypertension. J. Clin. Hypertens. (Greenwich) 2011, 13:224-237.
    • (2011) J. Clin. Hypertens. (Greenwich) , vol.13 , pp. 224-237
    • Hsueh, W.A.1    Wyne, K.2
  • 64
    • 29344452247 scopus 로고    scopus 로고
    • Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II
    • Hunyady L., Catt K.J. Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II. Mol. Endocrinol. 2006, 20:953-970.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 953-970
    • Hunyady, L.1    Catt, K.J.2
  • 67
    • 0034465456 scopus 로고    scopus 로고
    • Angiotensin II induces nuclear factor (NF)-kappaB1 isoforms to bind the angiotensinogen gene acute-phase response element: a stimulus-specific pathway for NF-kappaB activation
    • Jamaluddin M., Meng T., Sun J., Boldogh I., Han Y., Brasier A.R. Angiotensin II induces nuclear factor (NF)-kappaB1 isoforms to bind the angiotensinogen gene acute-phase response element: a stimulus-specific pathway for NF-kappaB activation. Mol. Endocrinol. 2000, 14:99-113.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 99-113
    • Jamaluddin, M.1    Meng, T.2    Sun, J.3    Boldogh, I.4    Han, Y.5    Brasier, A.R.6
  • 69
    • 0030956371 scopus 로고    scopus 로고
    • Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells
    • Jones B.H., Standridge M.K., Moustaid N. Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells. Endocrinology 1997, 138:1512-1519.
    • (1997) Endocrinology , vol.138 , pp. 1512-1519
    • Jones, B.H.1    Standridge, M.K.2    Moustaid, N.3
  • 71
    • 18844457924 scopus 로고    scopus 로고
    • Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression
    • Kanno K., Tazuma S., Nishioka T., Hyogo H., Chayama K. Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression. Dig. Dis. Sci. 2005, 50:942-948.
    • (2005) Dig. Dis. Sci. , vol.50 , pp. 942-948
    • Kanno, K.1    Tazuma, S.2    Nishioka, T.3    Hyogo, H.4    Chayama, K.5
  • 73
    • 14644418500 scopus 로고    scopus 로고
    • Mitochondria-derived reactive oxygen species and vascular MAP kinases: comparison of angiotensin II and diazoxide
    • Kimura S., Zhang G.X., Nishiyama A., Shokoji T., Yao L., Fan Y.Y., Rahman M., Abe Y. Mitochondria-derived reactive oxygen species and vascular MAP kinases: comparison of angiotensin II and diazoxide. Hypertension 2005, 45:438-444.
    • (2005) Hypertension , vol.45 , pp. 438-444
    • Kimura, S.1    Zhang, G.X.2    Nishiyama, A.3    Shokoji, T.4    Yao, L.5    Fan, Y.Y.6    Rahman, M.7    Abe, Y.8
  • 77
    • 0042168915 scopus 로고    scopus 로고
    • An angiotensin II type 1 receptor antagonist, olmesartan medoxomil, improves experimental liver fibrosis by suppression of proliferation and collagen synthesis in activated hepatic stellate cells
    • Kurikawa N., Suga M., Kuroda S., Yamada K., Ishikawa H. An angiotensin II type 1 receptor antagonist, olmesartan medoxomil, improves experimental liver fibrosis by suppression of proliferation and collagen synthesis in activated hepatic stellate cells. Br. J. Pharmacol. 2003, 139:1085-1094.
    • (2003) Br. J. Pharmacol. , vol.139 , pp. 1085-1094
    • Kurikawa, N.1    Suga, M.2    Kuroda, S.3    Yamada, K.4    Ishikawa, H.5
  • 79
    • 77958486859 scopus 로고    scopus 로고
    • The role of renin-angiotensin agents in altering the natural history of type 2 diabetes mellitus
    • Lardizabal J.A., Deedwania P.C. The role of renin-angiotensin agents in altering the natural history of type 2 diabetes mellitus. Curr. Cardiol. Rep. 2010, 12:464-471.
    • (2010) Curr. Cardiol. Rep. , vol.12 , pp. 464-471
    • Lardizabal, J.A.1    Deedwania, P.C.2
  • 81
    • 34249650125 scopus 로고    scopus 로고
    • Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences
    • Leclercq I.A., Da Silva Morais A., Schroyen B., Van Hul N., Geerts A. Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences. J. Hepatol. 2007, 47:142-156.
    • (2007) J. Hepatol. , vol.47 , pp. 142-156
    • Leclercq, I.A.1    Da Silva Morais, A.2    Schroyen, B.3    Van Hul, N.4    Geerts, A.5
  • 82
    • 0028838193 scopus 로고
    • Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression
    • Lee K.S., Buck M., Houglum K., Chojkier M. Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression. J. Clin. Invest. 1995, 96:2461-2468.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2461-2468
    • Lee, K.S.1    Buck, M.2    Houglum, K.3    Chojkier, M.4
  • 84
    • 33845476271 scopus 로고    scopus 로고
    • Angiotensin II and aldosterone stimulating NF-kappaB and AP-1 activation in hepatic fibrosis of rat
    • Li X., Meng Y., Wu P., Zhang Z., Yang X. Angiotensin II and aldosterone stimulating NF-kappaB and AP-1 activation in hepatic fibrosis of rat. Regul. Pept. 2007, 138:15-25.
    • (2007) Regul. Pept. , vol.138 , pp. 15-25
    • Li, X.1    Meng, Y.2    Wu, P.3    Zhang, Z.4    Yang, X.5
  • 87
    • 0034633804 scopus 로고    scopus 로고
    • Chronic exercise reduces sympathetic nerve activity in rabbits with pacing-induced heart failure: a role for angiotensin II
    • Liu J.L., Irvine S., Reid I.A., Patel K.P., Zucker I.H. Chronic exercise reduces sympathetic nerve activity in rabbits with pacing-induced heart failure: a role for angiotensin II. Circulation 2000, 102:1854-1862.
    • (2000) Circulation , vol.102 , pp. 1854-1862
    • Liu, J.L.1    Irvine, S.2    Reid, I.A.3    Patel, K.P.4    Zucker, I.H.5
  • 89
    • 49849093788 scopus 로고    scopus 로고
    • Liver disease and the renin-angiotensin system: recent discoveries and clinical implications
    • Lubel J.S., Herath C.B., Burrell L.M., Angus P.W. Liver disease and the renin-angiotensin system: recent discoveries and clinical implications. J. Gastroenterol. Hepatol. 2008, 23:1327-1338.
    • (2008) J. Gastroenterol. Hepatol. , vol.23 , pp. 1327-1338
    • Lubel, J.S.1    Herath, C.B.2    Burrell, L.M.3    Angus, P.W.4
  • 90
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: mayo clinic experiences with a hitherto unnamed disease
    • Ludwig J., Viggiano T.R., McGill D.B., Oh B.J. Nonalcoholic steatohepatitis: mayo clinic experiences with a hitherto unnamed disease. Mayo Clin. Proc. 1980, 55:434-438.
    • (1980) Mayo Clin. Proc. , vol.55 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3    Oh, B.J.4
  • 92
    • 45849086107 scopus 로고    scopus 로고
    • Role of the renin-angiotensin system in vascular inflammation
    • Marchesi C., Paradis P., Schiffrin E.L. Role of the renin-angiotensin system in vascular inflammation. Trends Pharmacol. Sci. 2008, 29:367-374.
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 367-374
    • Marchesi, C.1    Paradis, P.2    Schiffrin, E.L.3
  • 93
    • 79956159137 scopus 로고    scopus 로고
    • Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model
    • Matsunami T., Sato Y., Ariga S., Sato T., Shimomura T., Kashimura H., Hasegawa Y., Yukawa M. Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model. Metabolism 2011, 60:805-814.
    • (2011) Metabolism , vol.60 , pp. 805-814
    • Matsunami, T.1    Sato, Y.2    Ariga, S.3    Sato, T.4    Shimomura, T.5    Kashimura, H.6    Hasegawa, Y.7    Yukawa, M.8
  • 94
    • 0017875758 scopus 로고
    • Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA
    • McGarry J.D., Leatherman G.F., Foster D.W. Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA. J. Biol. Chem. 1978, 253:4128-4136.
    • (1978) J. Biol. Chem. , vol.253 , pp. 4128-4136
    • McGarry, J.D.1    Leatherman, G.F.2    Foster, D.W.3
  • 95
    • 33846362954 scopus 로고    scopus 로고
    • Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system
    • Mehta P.K., Griendling K.K. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am. J. Physiol. Cell Physiol. 2007, 292:C82-C97.
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292
    • Mehta, P.K.1    Griendling, K.K.2
  • 97
    • 0346788896 scopus 로고    scopus 로고
    • Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling
    • Miwa S., Brand M.D. Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling. Biochem. Soc. Trans. 2003, 31:1300-1301.
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 1300-1301
    • Miwa, S.1    Brand, M.D.2
  • 98
    • 36448991861 scopus 로고    scopus 로고
    • Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis
    • Miyazaki M., Flowers M.T., Sampath H., Chu K., Otzelberger C., Liu X., Ntambi J.M. Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab. 2007, 6:484-496.
    • (2007) Cell Metab. , vol.6 , pp. 484-496
    • Miyazaki, M.1    Flowers, M.T.2    Sampath, H.3    Chu, K.4    Otzelberger, C.5    Liu, X.6    Ntambi, J.M.7
  • 102
    • 79958779809 scopus 로고    scopus 로고
    • The role of the renin-angiotensin system in liver fibrosis
    • Munshi M.K., Uddin M.N., Glaser S.S. The role of the renin-angiotensin system in liver fibrosis. Exp. Biol. Med. (Maywood) 2011, 236:557-566.
    • (2011) Exp. Biol. Med. (Maywood) , vol.236 , pp. 557-566
    • Munshi, M.K.1    Uddin, M.N.2    Glaser, S.S.3
  • 103
    • 67349098446 scopus 로고    scopus 로고
    • Deletion of angiotensin II type I receptor reduces hepatic steatosis
    • Nabeshima Y., Tazuma S., Kanno K., Hyogo H., Chayama K. Deletion of angiotensin II type I receptor reduces hepatic steatosis. J. Hepatol. 2009, 50:1226-1235.
    • (2009) J. Hepatol. , vol.50 , pp. 1226-1235
    • Nabeshima, Y.1    Tazuma, S.2    Kanno, K.3    Hyogo, H.4    Chayama, K.5
  • 104
    • 77955690182 scopus 로고    scopus 로고
    • Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites
    • Neuschwander-Tetri B.A. Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites. Hepatology 2010, 52:774-788.
    • (2010) Hepatology , vol.52 , pp. 774-788
    • Neuschwander-Tetri, B.A.1
  • 105
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: summary of an AASLD single topic conference
    • Neuschwander-Tetri B.A., Caldwell S.H. Nonalcoholic steatohepatitis: summary of an AASLD single topic conference. Hepatology 2003, 37:1202-1219.
    • (2003) Hepatology , vol.37 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 106
    • 18444375296 scopus 로고    scopus 로고
    • Sustained diacylglycerol accumulation resulting from prolonged G protein-coupled receptor agonist-induced phosphoinositide breakdown in hepatocytes
    • Nilssen L.S., Dajani O., Christoffersen T., Sandnes D. Sustained diacylglycerol accumulation resulting from prolonged G protein-coupled receptor agonist-induced phosphoinositide breakdown in hepatocytes. J. Cell. Biochem. 2005, 94:389-402.
    • (2005) J. Cell. Biochem. , vol.94 , pp. 389-402
    • Nilssen, L.S.1    Dajani, O.2    Christoffersen, T.3    Sandnes, D.4
  • 107
    • 77951738835 scopus 로고    scopus 로고
    • Paediatric non-alcoholic fatty liver disease
    • Nobili V., Pinzani M. Paediatric non-alcoholic fatty liver disease. Gut 2010, 59:561-564.
    • (2010) Gut , vol.59 , pp. 561-564
    • Nobili, V.1    Pinzani, M.2
  • 108
    • 13844262622 scopus 로고    scopus 로고
    • Intracellular generation of reactive oxygen species by mitochondria
    • Nohl H., Gille L., Staniek K. Intracellular generation of reactive oxygen species by mitochondria. Biochem. Pharmacol. 2005, 69:719-723.
    • (2005) Biochem. Pharmacol. , vol.69 , pp. 719-723
    • Nohl, H.1    Gille, L.2    Staniek, K.3
  • 109
    • 74549159752 scopus 로고    scopus 로고
    • Prevalence of high body mass index in US children and adolescents, 2007-2008
    • Ogden C.L., Carroll M.D., Curtin L.R., Lamb M.M., Flegal K.M. Prevalence of high body mass index in US children and adolescents, 2007-2008. JAMA 2010, 303:242-249.
    • (2010) JAMA , vol.303 , pp. 242-249
    • Ogden, C.L.1    Carroll, M.D.2    Curtin, L.R.3    Lamb, M.M.4    Flegal, K.M.5
  • 114
    • 79955091590 scopus 로고    scopus 로고
    • The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice
    • Paik Y.H., Iwaisako K., Seki E., Inokuchi S., Schnabl B., Osterreicher C.H., Kisseleva T., Brenner D.A. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology 2011, 53:1730-1741.
    • (2011) Hepatology , vol.53 , pp. 1730-1741
    • Paik, Y.H.1    Iwaisako, K.2    Seki, E.3    Inokuchi, S.4    Schnabl, B.5    Osterreicher, C.H.6    Kisseleva, T.7    Brenner, D.A.8
  • 116
    • 67449161762 scopus 로고    scopus 로고
    • Angiotensin II downregulates the fatty acid oxidation pathway in adult rat cardiomyocytes via release of tumour necrosis factor-alpha
    • Pellieux C., Montessuit C., Papageorgiou I., Lerch R. Angiotensin II downregulates the fatty acid oxidation pathway in adult rat cardiomyocytes via release of tumour necrosis factor-alpha. Cardiovasc. Res. 2009, 82:341-350.
    • (2009) Cardiovasc. Res. , vol.82 , pp. 341-350
    • Pellieux, C.1    Montessuit, C.2    Papageorgiou, I.3    Lerch, R.4
  • 119
    • 18844389970 scopus 로고    scopus 로고
    • NASH: a mitochondrial disease
    • Pessayre D., Fromenty B. NASH: a mitochondrial disease. J. Hepatol. 2005, 42:928-940.
    • (2005) J. Hepatol. , vol.42 , pp. 928-940
    • Pessayre, D.1    Fromenty, B.2
  • 121
    • 6044267993 scopus 로고    scopus 로고
    • Chronic ANG II infusion increases plasma triglyceride level by stimulating hepatic triglyceride production in rats
    • Ran J., Hirano T., Adachi M. Chronic ANG II infusion increases plasma triglyceride level by stimulating hepatic triglyceride production in rats. Am. J. Physiol. Endocrinol. Metab. 2004, 287:E955-E961.
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.287
    • Ran, J.1    Hirano, T.2    Adachi, M.3
  • 122
    • 3242706039 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blocker ameliorates overproduction and accumulation of triglyceride in the liver of Zucker fatty rats
    • Ran J., Hirano T., Adachi M. Angiotensin II type 1 receptor blocker ameliorates overproduction and accumulation of triglyceride in the liver of Zucker fatty rats. Am. J. Physiol. Endocrinol. Metab. 2004, 287:E227-E232.
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.287
    • Ran, J.1    Hirano, T.2    Adachi, M.3
  • 123
    • 23344431676 scopus 로고    scopus 로고
    • Angiotensin II infusion increases hepatic triglyceride production via its type 2 receptor in rats
    • Ran J., Hirano T., Adachi M. Angiotensin II infusion increases hepatic triglyceride production via its type 2 receptor in rats. J. Hypertens. 2005, 23:1525-1530.
    • (2005) J. Hypertens. , vol.23 , pp. 1525-1530
    • Ran, J.1    Hirano, T.2    Adachi, M.3
  • 124
    • 39849099669 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease and the metabolic syndrome: an update
    • Rector R.S., Thyfault J.P., Wei Y., Ibdah J.A. Non-alcoholic fatty liver disease and the metabolic syndrome: an update. World J. Gastroenterol. 2008, 14:185-192.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 185-192
    • Rector, R.S.1    Thyfault, J.P.2    Wei, Y.3    Ibdah, J.A.4
  • 129
    • 77954343320 scopus 로고    scopus 로고
    • Irbesartan treatment up-regulates hepatic expression of PPARalpha and its target genes in obese Koletsky (fa(k)/fa(k)) rats: a link to amelioration of hypertriglyceridaemia
    • Rong X., Li Y., Ebihara K., Zhao M., Kusakabe T., Tomita T., Murray M., Nakao K. Irbesartan treatment up-regulates hepatic expression of PPARalpha and its target genes in obese Koletsky (fa(k)/fa(k)) rats: a link to amelioration of hypertriglyceridaemia. Br. J. Pharmacol. 2010, 160:1796-1807.
    • (2010) Br. J. Pharmacol. , vol.160 , pp. 1796-1807
    • Rong, X.1    Li, Y.2    Ebihara, K.3    Zhao, M.4    Kusakabe, T.5    Tomita, T.6    Murray, M.7    Nakao, K.8
  • 130
    • 0031858761 scopus 로고    scopus 로고
    • Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis
    • Ruiz-Ortega M., Bustos C., Hernandez-Presa M.A., Lorenzo O., Plaza J.J., Egido J. Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis. J. Immunol. 1998, 161:430-439.
    • (1998) J. Immunol. , vol.161 , pp. 430-439
    • Ruiz-Ortega, M.1    Bustos, C.2    Hernandez-Presa, M.A.3    Lorenzo, O.4    Plaza, J.J.5    Egido, J.6
  • 131
    • 0035022368 scopus 로고    scopus 로고
    • Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors
    • Ruiz-Ortega M., Lorenzo O., Ruperez M., Blanco J., Egido J. Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors. Am. J. Pathol. 2001, 158:1743-1756.
    • (2001) Am. J. Pathol. , vol.158 , pp. 1743-1756
    • Ruiz-Ortega, M.1    Lorenzo, O.2    Ruperez, M.3    Blanco, J.4    Egido, J.5
  • 132
    • 33750454286 scopus 로고    scopus 로고
    • Alanine aminotransferase as a marker of non-alcoholic fatty liver disease in relation to type 2 diabetes mellitus and cardiovascular disease
    • Schindhelm R.K., Diamant M., Dekker J.M., Tushuizen M.E., Teerlink T., Heine R.J. Alanine aminotransferase as a marker of non-alcoholic fatty liver disease in relation to type 2 diabetes mellitus and cardiovascular disease. Diabetes Metab. Res. Rev. 2006, 22:437-443.
    • (2006) Diabetes Metab. Res. Rev. , vol.22 , pp. 437-443
    • Schindhelm, R.K.1    Diamant, M.2    Dekker, J.M.3    Tushuizen, M.E.4    Teerlink, T.5    Heine, R.J.6
  • 135
    • 0036089571 scopus 로고    scopus 로고
    • Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure
    • Sorescu D., Griendling K.K. Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure. Congest. Heart Fail. 2002, 8:132-140.
    • (2002) Congest. Heart Fail. , vol.8 , pp. 132-140
    • Sorescu, D.1    Griendling, K.K.2
  • 136
    • 33646148948 scopus 로고    scopus 로고
    • Telmisartan but not valsartan increases caloric expenditure and protects against weight gain and hepatic steatosis
    • Sugimoto K., Qi N.R., Kazdova L., Pravenec M., Ogihara T., Kurtz T.W. Telmisartan but not valsartan increases caloric expenditure and protects against weight gain and hepatic steatosis. Hypertension 2006, 47:1003-1009.
    • (2006) Hypertension , vol.47 , pp. 1003-1009
    • Sugimoto, K.1    Qi, N.R.2    Kazdova, L.3    Pravenec, M.4    Ogihara, T.5    Kurtz, T.W.6
  • 137
    • 43449087025 scopus 로고    scopus 로고
    • Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway
    • Sugimoto K., Kazdova L., Qi N.R., Hyakukoku M., Kren V., Simakova M., Zidek V., Kurtz T.W., Pravenec M. Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway. J. Hypertens. 2008, 26:1209-1215.
    • (2008) J. Hypertens. , vol.26 , pp. 1209-1215
    • Sugimoto, K.1    Kazdova, L.2    Qi, N.R.3    Hyakukoku, M.4    Kren, V.5    Simakova, M.6    Zidek, V.7    Kurtz, T.W.8    Pravenec, M.9
  • 138
    • 79955633419 scopus 로고    scopus 로고
    • The forgotten face of regular physical exercise: a 'natural' anti-atherogenic activity
    • Szostak J., Laurant P. The forgotten face of regular physical exercise: a 'natural' anti-atherogenic activity. Clin. Sci. (Lond.) 2011, 121:91-106.
    • (2011) Clin. Sci. (Lond.) , vol.121 , pp. 91-106
    • Szostak, J.1    Laurant, P.2
  • 139
    • 36448954594 scopus 로고    scopus 로고
    • Increased energy expenditure, dietary fat wasting, and resistance to diet-induced obesity in mice lacking renin
    • Takahashi N., Li F., Hua K., Deng J., Wang C.H., Bowers R.R., Bartness T.J., Kim H.S., Harp J.B. Increased energy expenditure, dietary fat wasting, and resistance to diet-induced obesity in mice lacking renin. Cell Metab. 2007, 6:506-512.
    • (2007) Cell Metab. , vol.6 , pp. 506-512
    • Takahashi, N.1    Li, F.2    Hua, K.3    Deng, J.4    Wang, C.H.5    Bowers, R.R.6    Bartness, T.J.7    Kim, H.S.8    Harp, J.B.9
  • 140
    • 37549027272 scopus 로고    scopus 로고
    • Cross talk of tumor necrosis factor-alpha and the renin-angiotensin system in tumor necrosis factor-alpha-induced plasminogen activator inhibitor-1 production from hepatocytes
    • Takeshita Y., Takamura T., Ando H., Hamaguchi E., Takazakura A., Matsuzawa-Nagata N., Kaneko S. Cross talk of tumor necrosis factor-alpha and the renin-angiotensin system in tumor necrosis factor-alpha-induced plasminogen activator inhibitor-1 production from hepatocytes. Eur. J. Pharmacol. 2008, 579:426-432.
    • (2008) Eur. J. Pharmacol. , vol.579 , pp. 426-432
    • Takeshita, Y.1    Takamura, T.2    Ando, H.3    Hamaguchi, E.4    Takazakura, A.5    Matsuzawa-Nagata, N.6    Kaneko, S.7
  • 141
    • 83555176039 scopus 로고    scopus 로고
    • Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: a systematic review
    • Thoma C., Day C.P., Trenell M.I. Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: a systematic review. J. Hepatol. 2012, 56:255-266.
    • (2012) J. Hepatol. , vol.56 , pp. 255-266
    • Thoma, C.1    Day, C.P.2    Trenell, M.I.3
  • 143
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • Tilg H., Diehl A.M. Cytokines in alcoholic and nonalcoholic steatohepatitis. N. Engl. J. Med. 2000, 343:1467-1476.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1467-1476
    • Tilg, H.1    Diehl, A.M.2
  • 144
    • 41549156590 scopus 로고    scopus 로고
    • ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats
    • Toblli J.E., Munoz M.C., Cao G., Mella J., Pereyra L., Mastai R. ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats. Obesity (Silver Spring) 2008, 16:770-776.
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 770-776
    • Toblli, J.E.1    Munoz, M.C.2    Cao, G.3    Mella, J.4    Pereyra, L.5    Mastai, R.6
  • 145
    • 0037059013 scopus 로고    scopus 로고
    • Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
    • Tomas E., Tsao T.S., Saha A.K., Murrey H.E., Zhang Cc C., Itani S.I., Lodish H.F., Ruderman N.B. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc. Natl. Acad. Sci. USA 2002, 99:16309-16313.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 16309-16313
    • Tomas, E.1    Tsao, T.S.2    Saha, A.K.3    Murrey, H.E.4    Zhang Cc, C.5    Itani, S.I.6    Lodish, H.F.7    Ruderman, N.B.8
  • 146
    • 70449706044 scopus 로고    scopus 로고
    • Adipokines in nonalcoholic steatohepatitis: from pathogenesis to implications in diagnosis and therapy
    • Tsochatzis E.A., Papatheodoridis G.V., Archimandritis A.J. Adipokines in nonalcoholic steatohepatitis: from pathogenesis to implications in diagnosis and therapy. Mediators Inflamm. 2009, 2009:831670.
    • (2009) Mediators Inflamm. , vol.2009 , pp. 831670
    • Tsochatzis, E.A.1    Papatheodoridis, G.V.2    Archimandritis, A.J.3
  • 151
    • 65349125289 scopus 로고    scopus 로고
    • Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic Ren2 rats
    • Wei Y., Clark S.E., Thyfault J.P., Uptergrove G.M., Li W., Whaley-Connell A.T., Ferrario C.M., Sowers J.R., Ibdah J.A. Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic Ren2 rats. Am. J. Pathol. 2009, 174:1329-1337.
    • (2009) Am. J. Pathol. , vol.174 , pp. 1329-1337
    • Wei, Y.1    Clark, S.E.2    Thyfault, J.P.3    Uptergrove, G.M.4    Li, W.5    Whaley-Connell, A.T.6    Ferrario, C.M.7    Sowers, J.R.8    Ibdah, J.A.9
  • 153
    • 30944451953 scopus 로고    scopus 로고
    • Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus
    • Wilson P.W., D'Agostino R.B., Parise H., Sullivan L., Meigs J.B. Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation 2005, 112:3066-3072.
    • (2005) Circulation , vol.112 , pp. 3066-3072
    • Wilson, P.W.1    D'Agostino, R.B.2    Parise, H.3    Sullivan, L.4    Meigs, J.B.5
  • 155
    • 79955784400 scopus 로고    scopus 로고
    • MCP-1: chemoattractant with a role beyond immunity: a review
    • Yadav A., Saini V., Arora S. MCP-1: chemoattractant with a role beyond immunity: a review. Clin. Chim. Acta 2010, 411:1570-1579.
    • (2010) Clin. Chim. Acta , vol.411 , pp. 1570-1579
    • Yadav, A.1    Saini, V.2    Arora, S.3
  • 156
    • 52049105198 scopus 로고    scopus 로고
    • Olmesartan prevents cardiovascular injury and hepatic steatosis in obesity and diabetes, accompanied by apoptosis signal regulating kinase-1 inhibition
    • Yamamoto E., Dong Y.F., Kataoka K., Yamashita T., Tokutomi Y., Matsuba S., Ichijo H., Ogawa H., Kim-Mitsuyama S. Olmesartan prevents cardiovascular injury and hepatic steatosis in obesity and diabetes, accompanied by apoptosis signal regulating kinase-1 inhibition. Hypertension 2008, 52:573-580.
    • (2008) Hypertension , vol.52 , pp. 573-580
    • Yamamoto, E.1    Dong, Y.F.2    Kataoka, K.3    Yamashita, T.4    Tokutomi, Y.5    Matsuba, S.6    Ichijo, H.7    Ogawa, H.8    Kim-Mitsuyama, S.9
  • 160
    • 67449101455 scopus 로고    scopus 로고
    • Down-regulation of hepatic stearoyl-CoA desaturase 1 expression by angiotensin II receptor blocker in the obese fa/fa Zucker rat: possible role in amelioration of insulin resistance and hepatic steatosis
    • Yokozawa J., Sasaki T., Ohwada K., Sasaki Y., Ito J.I., Saito T., Kawata S. Down-regulation of hepatic stearoyl-CoA desaturase 1 expression by angiotensin II receptor blocker in the obese fa/fa Zucker rat: possible role in amelioration of insulin resistance and hepatic steatosis. J. Gastroenterol. 2009, 44:583-591.
    • (2009) J. Gastroenterol. , vol.44 , pp. 583-591
    • Yokozawa, J.1    Sasaki, T.2    Ohwada, K.3    Sasaki, Y.4    Ito, J.I.5    Saito, T.6    Kawata, S.7
  • 161
    • 0036211568 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: an agenda for clinical research
    • Younossi Z.M., Diehl A.M., Ong J.P. Nonalcoholic fatty liver disease: an agenda for clinical research. Hepatology 2002, 35:746-752.
    • (2002) Hepatology , vol.35 , pp. 746-752
    • Younossi, Z.M.1    Diehl, A.M.2    Ong, J.P.3
  • 163
    • 78650919357 scopus 로고    scopus 로고
    • Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity
    • Yvan-Charvet L., Quignard-Boulange A. Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity. Kidney Int. 2011, 79:162-168.
    • (2011) Kidney Int. , vol.79 , pp. 162-168
    • Yvan-Charvet, L.1    Quignard-Boulange, A.2
  • 164
    • 15944377334 scopus 로고    scopus 로고
    • Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance
    • Yvan-Charvet L., Even P., Bloch-Faure M., Guerre-Millo M., Moustaid-Moussa N., Ferre P., Quignard-Boulange A. Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance. Diabetes 2005, 54:991-999.
    • (2005) Diabetes , vol.54 , pp. 991-999
    • Yvan-Charvet, L.1    Even, P.2    Bloch-Faure, M.3    Guerre-Millo, M.4    Moustaid-Moussa, N.5    Ferre, P.6    Quignard-Boulange, A.7


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