메뉴 건너뛰기




Volumn 60, Issue 6, 2011, Pages 805-814

Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE 1; ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; ALANINE AMINOTRANSFERASE; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEPATOCYTE NUCLEAR FACTOR 3BETA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA2; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MESSENGER RNA; MONOUNSATURATED FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SATURATED FATTY ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 79956159137     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2010.07.032     Document Type: Article
Times cited : (39)

References (48)
  • 2
    • 0036176194 scopus 로고    scopus 로고
    • Update on nonalcoholic fatty liver disease
    • DOI 10.1097/00004836-200203000-00013
    • McCullough AJ. Update on nonalcoholic fatty liver disease. J Clin Gastroenterol 2002;34:255-62. (Pubitemid 34177381)
    • (2002) Journal of Clinical Gastroenterology , vol.34 , Issue.3 , pp. 255-262
    • McCullough, A.J.1
  • 6
    • 18844432308 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors
    • DOI 10.1210/er.2005-0005
    • Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev 2005;26:439-51. (Pubitemid 40686653)
    • (2005) Endocrine Reviews , vol.26 , Issue.3 , pp. 439-451
    • Kadowaki, T.1    Yamauchi, T.2
  • 7
    • 34548804940 scopus 로고    scopus 로고
    • Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: Possible role of vitamin a intake
    • Musso G, Gambino R, De Michieli F, et al. Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake. Am J Clin Nutr 2007;86:661-71. (Pubitemid 47435833)
    • (2007) American Journal of Clinical Nutrition , vol.86 , Issue.3 , pp. 661-671
    • Musso, G.1    Gambino, R.2    De Michieli, F.3    Biroli, G.4    Premoli, A.5    Pagano, G.6    Bo, S.7    Durazzo, M.8    Cassader, M.9
  • 10
  • 11
    • 0034693259 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
    • Osborne TF. Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action. J Biol Chem 2000;275:32379-82.
    • (2000) J Biol Chem , vol.275 , pp. 32379-32382
    • Osborne, T.F.1
  • 13
    • 2642683510 scopus 로고    scopus 로고
    • Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse
    • Kerouz NJ, Horsch D, Pons S, Kahn CR. Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse. J Clin Invest 1997;100:3164-72. (Pubitemid 28022855)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.12 , pp. 3164-3172
    • Kerouz, N.J.1    Horsch, D.2    Pons, S.3    Kahn, C.R.4
  • 14
    • 11144244418 scopus 로고    scopus 로고
    • Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes
    • DOI 10.1038/nature03047
    • Wolfrum C, Asilmaz E, Luca E, Friedman JM, Stoffel M. Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature 2004;432:1027-32. (Pubitemid 40052233)
    • (2004) Nature , vol.432 , Issue.7020 , pp. 1027-1032
    • Wolfrum, C.1    Asilmaz, E.2    Luca, E.3    Friedman, J.M.4    Stoffel, M.5
  • 15
    • 14644426519 scopus 로고    scopus 로고
    • Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
    • DOI 10.1172/JCI200523187
    • Taniguchi CM, Ueki K, Kahn R. Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism. J Clin Invest 2005;115:718-27. (Pubitemid 40322247)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.3 , pp. 718-727
    • Taniguchi, C.M.1    Ueki, K.2    Kahn, C.R.3
  • 16
    • 0038532266 scopus 로고    scopus 로고
    • Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes
    • DOI 10.1074/jbc.M209363200
    • Valverde AM, Arribas M, Mur C, et al. Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes. J Biol Chem 2003;278:10221-31. (Pubitemid 36800283)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.12 , pp. 10221-10231
    • Valverde, A.M.1    Arribas, M.2    Mur, C.3    Navarro, P.4    Pons, S.5    Cassard-Doulcier, A.-M.6    Kahn, C.R.7    Benito, M.8
  • 18
    • 31044446941 scopus 로고    scopus 로고
    • Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth
    • DOI 10.1172/JCI25735
    • Dong X, Park S, Lin X, et al. Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth. J Clin Invest 2006;116:101-14. (Pubitemid 43121795)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.1 , pp. 101-114
    • Dong, X.1    Park, S.2    Lin, X.3    Copps, K.4    Yi, X.5    White, M.F.6
  • 20
    • 0026343403 scopus 로고
    • Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy
    • Meister A. Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy. Pharmacol Ther 1991;51:155-94.
    • (1991) Pharmacol Ther , vol.51 , pp. 155-194
    • Meister, A.1
  • 21
    • 0023952554 scopus 로고
    • A simple method for clinical assay of superoxide dismutase
    • Sun Y, Oberley LW, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem 1988;34:497-500.
    • (1988) Clin Chem , vol.34 , pp. 497-500
    • Sun, Y.1    Oberley, L.W.2    Li, Y.3
  • 22
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol 1984;105:121-6.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 23
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158-69.
    • (1967) J Lab Clin Med , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 24
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-8. (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 26
    • 0034694128 scopus 로고    scopus 로고
    • Effect of experimental treatment on housekeeping gene expression: Validation by real-time, quantitative RT-PCR
    • Schmittgen TD, Zakrajsek BA. Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR. J Biochem Biophys Methods 2000;46:69-81.
    • (2000) J Biochem Biophys Methods , vol.46 , pp. 69-81
    • Schmittgen, T.D.1    Zakrajsek, B.A.2
  • 27
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001;29:e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 28
    • 33745815985 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling in metabolic regulation
    • DOI 10.1172/JCI29044
    • Long YC, Zierath JR. AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest 2006;116:1776-83. (Pubitemid 44033297)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1776-1783
    • Yun, C.L.1    Zierath, J.R.2
  • 30
    • 0037329494 scopus 로고    scopus 로고
    • AMP-activated protein kinase regulates gene expression by direct phosphorylation of nuclear proteins
    • Leff T. AMP-activated protein kinase regulates gene expression by direct phosphorylation of nuclear proteins. Biochem Soc Trans 2003;31:224-7. (Pubitemid 36241433)
    • (2003) Biochemical Society Transactions , vol.31 , Issue.1 , pp. 224-227
    • Leff, T.1
  • 31
    • 47749113264 scopus 로고    scopus 로고
    • Improved mitochondrial function and increased life span after chronic melatonin treatment in senescent prone mice
    • Rodriguez MI, Escames G, Lopez LC, et al. Improved mitochondrial function and increased life span after chronic melatonin treatment in senescent prone mice. Exp Gerontol 2008;43:749-56.
    • (2008) Exp Gerontol , vol.43 , pp. 749-756
    • Rodriguez, M.I.1    Escames, G.2    Lopez, L.C.3
  • 32
    • 0345276007 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturases and role in metabolism
    • DOI 10.1016/S0163-7827(03)00039-0
    • Ntambi JM, Miyazaki M. Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res 2004;43:91-104. (Pubitemid 37487985)
    • (2004) Progress in Lipid Research , vol.43 , Issue.2 , pp. 91-104
    • Ntambi, J.M.1    Miyazaki, M.2
  • 33
    • 33749323970 scopus 로고    scopus 로고
    • Safety and effectiveness of rosiglitazone in type 2 diabetes patients with nonalcoholic fatty liver disease
    • Wang CH, Leung CH, Liu SC, et al. Safety and effectiveness of rosiglitazone in type 2 diabetes patients with nonalcoholic fatty liver disease. J Formos Med Assoc 2006;105:743-52.
    • (2006) J Formos Med Assoc , vol.105 , pp. 743-752
    • Wang, C.H.1    Leung, C.H.2    Liu, S.C.3
  • 34
    • 38649124615 scopus 로고    scopus 로고
    • Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease
    • DOI 10.1053/j.gastro.2007.10.039, PII S0016508507019191
    • Puri P, Mirshahi F, Cheung O, et al. Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease. Gastroenterology 2008;134:568-76. (Pubitemid 351173040)
    • (2008) Gastroenterology , vol.134 , Issue.2 , pp. 568-576
    • Puri, P.1    Mirshahi, F.2    Cheung, O.3    Natarajan, R.4    Maher, J.W.5    Kellum, J.M.6    Sanyal, A.J.7
  • 35
    • 0036780582 scopus 로고    scopus 로고
    • Pathogenesis of steatohepatitis
    • Day CP. Pathogenesis of steatohepatitis. Best Pract Res Clin 2002;16:663-78.
    • (2002) Best Pract Res Clin , vol.16 , pp. 663-678
    • Day, C.P.1
  • 36
    • 0242285711 scopus 로고    scopus 로고
    • Ascorbic acid concentrations in dimethylnitrosamine-induced hepatic fibrosis in rats
    • DOI 10.1016/S0009-8981(03)00285-7
    • George J. Ascorbic acid concentrations in dimethylnitrosamine-induced hepatic fibrosis in rats. Clin Chim Acta 2003;335:39-47. (Pubitemid 37338306)
    • (2003) Clinica Chimica Acta , vol.335 , Issue.1-2 , pp. 39-47
    • George, J.1
  • 37
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • DOI 10.1172/JCI200422422
    • Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 2004;114:147-52. (Pubitemid 39071617)
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.2 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 38
    • 11244348954 scopus 로고    scopus 로고
    • A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats
    • DOI 10.1096/fj.04-2291fje
    • Carmiel-Haggai M, Cederbaum AI, Nieto N. A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. FASEB J 2005;19:136-8. (Pubitemid 40069943)
    • (2005) FASEB Journal , vol.19 , Issue.1 , pp. 136-138
    • Carmiel-Haggai, M.1    Cederbaum, A.I.2    Nieto, N.3
  • 39
    • 49649100197 scopus 로고    scopus 로고
    • Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice
    • Tomita K, Oike Y, Teratani T, et al. Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice. Hepatology 2008;48:458-73.
    • (2008) Hepatology , vol.48 , pp. 458-473
    • Tomita, K.1    Oike, Y.2    Teratani, T.3
  • 40
    • 58849119649 scopus 로고    scopus 로고
    • Expression of adiponectin and its receptors in livers of morbidly obese patients with non-alcoholic fatty liver disease
    • Ma H, Gomez V, Lu L, et al. Expression of adiponectin and its receptors in livers of morbidly obese patients with non-alcoholic fatty liver disease. J Gastroenterol Hepatol 2009;24:233-7.
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 233-237
    • Ma, H.1    Gomez, V.2    Lu, L.3
  • 43
    • 0033815967 scopus 로고    scopus 로고
    • Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase
    • Woods A, Azzout-Marniche D, Foretz M, et al. Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol Cell Biol 2000;20:6704-11.
    • (2000) Mol Cell Biol , vol.20 , pp. 6704-6711
    • Woods, A.1    Azzout-Marniche, D.2    Foretz, M.3
  • 44
    • 0033636780 scopus 로고    scopus 로고
    • Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
    • Shimomura I, Matsuda M, Hammer RE, et al. Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol Cell 2000;6:77-86.
    • (2000) Mol Cell , vol.6 , pp. 77-86
    • Shimomura, I.1    Matsuda, M.2    Hammer, R.E.3
  • 48
    • 0034939632 scopus 로고    scopus 로고
    • Peroxisomal beta-oxidation and peroxisome proliferator - Activated receptor alpha: An adaptive metabolic system
    • DOI 10.1146/annurev.nutr.21.1.193
    • Reddy JK, Hashimoto T. Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system. Annu Rev Nutr 2001;21:193-230. (Pubitemid 32695270)
    • (2001) Annual Review of Nutrition , vol.21 , pp. 193-230
    • Reddy, J.K.1    Hashimoto, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.