Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury

Journal of Physiology

Volumn 587, Issue 8, 2009, Pages 1805-1816

  Thyfault, John P ^a,b   Rector, R Scott ^b   Uptergrove, Grace M ^b   Borengasser, Sarah J ^b   Morris, E Matthew ^b   Wei, Yongzhong ^b   Laye, Matt J ^b   Burant, Charles F ^c   Qi, Nathan R ^c   Ridenhour, Suzanne E ^b   Koch, Lauren G ^c   Britton, Steve L ^c   Ibdah, Jamal A ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b University of Missouri   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A OXIDASE; ALANINE AMINOTRANSFERASE; CATALASE; CITRATE SYNTHASE; CYTOCHROME C; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; FAT DROPLET; PALMITIC ACID;

AEROBIC CAPACITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME ACTIVITY; EXPERIMENTAL RAT; FATTY LIVER; LIPID PEROXIDATION; LIPOGENESIS; LIVER CELL; LIVER INJURY; LIVER MITOCHONDRION; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXYGEN CONSUMPTION; PEROXISOME; PHENOTYPE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; TRIACYLGLYCEROL BLOOD LEVEL; APOPTOSIS; FATTY ACID OXIDATION; LIPID LIVER LEVEL; LIPID STORAGE; LIVER FIBROSIS; LIVER HISTOLOGY; MALE;

ANAEROBIC THRESHOLD; ANIMALS; APOPTOSIS; BLOOD PRESSURE; BLOTTING, WESTERN; EATING; FATTY LIVER; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; LIPID METABOLISM; LIPID PEROXIDATION; LIVER; LIVER DISEASES; MALE; MITOCHONDRIA, LIVER; OXIDATION-REDUCTION; PALMITATES; PEROXISOMES; PHENOTYPE; PHYSICAL CONDITIONING, ANIMAL; RATS;

EID: 65249156393     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2009.169060     Document Type: Article

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