메뉴 건너뛰기




Volumn 8, Issue 9, 2013, Pages

Undifferentiated and Differentiated PC12 Cells Protected by Huprines Against Injury Induced by Hydrogen Peroxide

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; CHOLINERGIC RECEPTOR; CHOLINESTERASE INHIBITOR; HUPRINE X; HUPRINE Y; HUPRINE Z; HYDROGEN PEROXIDE; MECAMYLAMINE; MUSCARINIC RECEPTOR; NERVE GROWTH FACTOR; NICOTINIC RECEPTOR; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 84884505413     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074344     Document Type: Article
Times cited : (19)

References (61)
  • 1
    • 70350075694 scopus 로고    scopus 로고
    • Neuroscience: Alzheimer's disease
    • Mucke L, (2009) Neuroscience: Alzheimer's disease. Nature 461: 895-897.
    • (2009) Nature , vol.461 , pp. 895-897
    • Mucke, L.1
  • 2
    • 84871919598 scopus 로고    scopus 로고
    • Excitotoxicity: bridge to various triggers in neurodegenerative disorders
    • Mehta A, Prabhakar M, Kumar P, Deshmukh R, Sharma PL, (2013) Excitotoxicity: bridge to various triggers in neurodegenerative disorders. Eur J Pharmacol 698: 6-18.
    • (2013) Eur J Pharmacol , vol.698 , pp. 6-18
    • Mehta, A.1    Prabhakar, M.2    Kumar, P.3    Deshmukh, R.4    Sharma, P.L.5
  • 3
    • 0032902974 scopus 로고    scopus 로고
    • Oxidative alterations in Alzheimer's disease
    • Markesbery WR, Carney JM, (1999) Oxidative alterations in Alzheimer's disease. Brain Pathol 9: 133-146.
    • (1999) Brain Pathol , vol.9 , pp. 133-146
    • Markesbery, W.R.1    Carney, J.M.2
  • 4
    • 0028178837 scopus 로고
    • beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease
    • Butterfield DA, Hensley K, Harris M, Mattson M, Carney J, (1994) beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease. Biochem Biophys Res Commun 200: 710-715.
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 710-715
    • Butterfield, D.A.1    Hensley, K.2    Harris, M.3    Mattson, M.4    Carney, J.5
  • 5
    • 0030928406 scopus 로고    scopus 로고
    • beta-Amyloid-associated free radical oxidative stress and neurotoxicity: implications for Alzheimer's disease
    • Butterfield DA, (1997) beta-Amyloid-associated free radical oxidative stress and neurotoxicity: implications for Alzheimer's disease. Chem Res Toxicol 10: 495-506.
    • (1997) Chem Res Toxicol , vol.10 , pp. 495-506
    • Butterfield, D.A.1
  • 6
    • 67849097738 scopus 로고    scopus 로고
    • Oxidative stress in vascular dementia and Alzheimer's disease: a common pathology
    • Bennett S, Grant MM, Aldred S, (2009) Oxidative stress in vascular dementia and Alzheimer's disease: a common pathology. J Alzheimers Dis 17: 245-257.
    • (2009) J Alzheimers Dis , vol.17 , pp. 245-257
    • Bennett, S.1    Grant, M.M.2    Aldred, S.3
  • 7
    • 78449282609 scopus 로고    scopus 로고
    • Metals, oxidative stress and neurodegenerative disorders
    • Jomova K, Vondrakova D, Lawson M, Valko M, (2010) Metals, oxidative stress and neurodegenerative disorders. Mol Cell Biochem 345: 91-104.
    • (2010) Mol Cell Biochem , vol.345 , pp. 91-104
    • Jomova, K.1    Vondrakova, D.2    Lawson, M.3    Valko, M.4
  • 8
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid beta protein toxicity
    • Behl C, Davis JB, Lesley R, Schubert D, (1994) Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 77: 817-827.
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 9
    • 33748466130 scopus 로고    scopus 로고
    • Apoptosis in Alzheimer disease: a mathematical improbability
    • Zhu X, Raina AK, Perry G, Smith MA, (2006) Apoptosis in Alzheimer disease: a mathematical improbability. Curr Alzheimer Res 3: 393-396.
    • (2006) Curr Alzheimer Res , vol.3 , pp. 393-396
    • Zhu, X.1    Raina, A.K.2    Perry, G.3    Smith, M.A.4
  • 10
    • 57249084239 scopus 로고    scopus 로고
    • Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling
    • Gorman AM, (2008) Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling. J Cell Mol Med 12: 2263-2280.
    • (2008) J Cell Mol Med , vol.12 , pp. 2263-2280
    • Gorman, A.M.1
  • 11
    • 84878111480 scopus 로고    scopus 로고
    • Reconsider Alzheimer's disease by the 'calpain-cathepsin hypothesis'-A perspective review
    • Yamashima T (2013) Reconsider Alzheimer's disease by the 'calpain-cathepsin hypothesis'-A perspective review. Prog Neurobiol.
    • (2013) Prog Neurobiol
    • Yamashima, T.1
  • 13
    • 12844271665 scopus 로고    scopus 로고
    • A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease?
    • Francis PT, Nordberg A, Arnold SE, (2005) A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease? Trends Pharmacol Sci 26: 104-111.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 104-111
    • Francis, P.T.1    Nordberg, A.2    Arnold, S.E.3
  • 14
    • 0034082560 scopus 로고    scopus 로고
    • Cholinesterase inhibitor therapy stabilizes symptoms of Alzheimer disease
    • Giacobini E, (2000) Cholinesterase inhibitor therapy stabilizes symptoms of Alzheimer disease. Alzheimer Dis Assoc Disord 14Suppl 1: S3-10.
    • (2000) Alzheimer Dis Assoc Disord , vol.14 , Issue.SUPPL. 1 , pp. 3-10
    • Giacobini, E.1
  • 15
    • 77954369899 scopus 로고    scopus 로고
    • Beyond the cholinergic hypothesis: do current drugs work in Alzheimer's disease?
    • Martorana A, Esposito Z, Koch G, (2010) Beyond the cholinergic hypothesis: do current drugs work in Alzheimer's disease? CNS Neurosci Ther 16: 235-245.
    • (2010) CNS Neurosci Ther , vol.16 , pp. 235-245
    • Martorana, A.1    Esposito, Z.2    Koch, G.3
  • 16
    • 75049085215 scopus 로고    scopus 로고
    • Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of alpha4 and alpha7 receptors in neuroprotection
    • Akaike A, Takada-Takatori Y, Kume T, Izumi Y, (2010) Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of alpha4 and alpha7 receptors in neuroprotection. J Mol Neurosci 40: 211-216.
    • (2010) J Mol Neurosci , vol.40 , pp. 211-216
    • Akaike, A.1    Takada-Takatori, Y.2    Kume, T.3    Izumi, Y.4
  • 17
    • 84876375022 scopus 로고    scopus 로고
    • Alzheimer disease pharmacologic treatment and treatment research
    • Schneider LS, (2013) Alzheimer disease pharmacologic treatment and treatment research. Continuum (Minneap Minn) 19: 339-357.
    • (2013) Continuum (Minneap Minn) , vol.19 , pp. 339-357
    • Schneider, L.S.1
  • 18
    • 84873743958 scopus 로고    scopus 로고
    • Galantamine increases hippocampal insulin-like growth factor 2 expression via alpha7 nicotinic acetylcholine receptors in mice
    • Kita Y, Ago Y, Takano E, Fukada A, Takuma K, et al. (2013) Galantamine increases hippocampal insulin-like growth factor 2 expression via alpha7 nicotinic acetylcholine receptors in mice. Psychopharmacology (Berl) 225: 543-551.
    • (2013) Psychopharmacology (Berl) , vol.225 , pp. 543-551
    • Kita, Y.1    Ago, Y.2    Takano, E.3    Fukada, A.4    Takuma, K.5
  • 19
    • 84862785007 scopus 로고    scopus 로고
    • Donepezil attenuates hippocampal neuronal damage and cognitive deficits after global cerebral ischemia in gerbils
    • Min D, Mao X, Wu K, Cao Y, Guo F, et al. (2012) Donepezil attenuates hippocampal neuronal damage and cognitive deficits after global cerebral ischemia in gerbils. Neurosci Lett 510: 29-33.
    • (2012) Neurosci Lett , vol.510 , pp. 29-33
    • Min, D.1    Mao, X.2    Wu, K.3    Cao, Y.4    Guo, F.5
  • 20
    • 20444381285 scopus 로고    scopus 로고
    • Protective effect of donepezil against Abeta(1-40) neurotoxicity in rat septal neurons
    • Kimura M, Akasofu S, Ogura H, Sawada K, (2005) Protective effect of donepezil against Abeta(1-40) neurotoxicity in rat septal neurons. Brain Res 1047: 72-84.
    • (2005) Brain Res , vol.1047 , pp. 72-84
    • Kimura, M.1    Akasofu, S.2    Ogura, H.3    Sawada, K.4
  • 21
    • 27744436607 scopus 로고    scopus 로고
    • Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors
    • Arias E, Gallego-Sandin S, Villarroya M, Garcia AG, Lopez MG, (2005) Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors. J Pharmacol Exp Ther 315: 1346-1353.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 1346-1353
    • Arias, E.1    Gallego-Sandin, S.2    Villarroya, M.3    Garcia, A.G.4    Lopez, M.G.5
  • 23
    • 0032054003 scopus 로고    scopus 로고
    • Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcolinesterase inhibitors of potential interest for the treatment of Alzheimer's disease
    • Badia A, Baños JE, Camps P, Contreras J, Görbig DM, et al. (1998) Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcolinesterase inhibitors of potential interest for the treatment of Alzheimer's disease. Bioorg Med Chem 6: 427-440.
    • (1998) Bioorg Med Chem , vol.6 , pp. 427-440
    • Badia, A.1    Baños, J.E.2    Camps, P.3    Contreras, J.4    Görbig, D.M.5
  • 24
    • 0034736034 scopus 로고    scopus 로고
    • New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease
    • Camps P, El Achab R, Morral J, Muñoz-Torrero D, Badia A, et al. (2000) New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease. J Med Chem 43: 4657-4666.
    • (2000) J Med Chem , vol.43 , pp. 4657-4666
    • Camps, P.1    El Achab, R.2    Morral, J.3    Muñoz-Torrero, D.4    Badia, A.5
  • 25
    • 0037036219 scopus 로고    scopus 로고
    • Interaction of a new potent anticholinesterasic compound (+/-)huprine X with muscarinic receptors in rat brain
    • Roman S, Vivas NM, Badia A, Clos MV, (2002) Interaction of a new potent anticholinesterasic compound (+/-)huprine X with muscarinic receptors in rat brain. Neurosci Lett 325: 103-106.
    • (2002) Neurosci Lett , vol.325 , pp. 103-106
    • Roman, S.1    Vivas, N.M.2    Badia, A.3    Clos, M.V.4
  • 26
    • 0344256513 scopus 로고    scopus 로고
    • Potentiation effects of (+/-)huprine X, a new acetylcholinesterase inhibitor, on nicotinic receptors in rat cortical synaptosomes
    • Roman S, Badia A, Camps P, Clos MV, (2004) Potentiation effects of (+/-)huprine X, a new acetylcholinesterase inhibitor, on nicotinic receptors in rat cortical synaptosomes. Neuropharmacology 46: 95-102.
    • (2004) Neuropharmacology , vol.46 , pp. 95-102
    • Roman, S.1    Badia, A.2    Camps, P.3    Clos, M.V.4
  • 28
    • 59049092791 scopus 로고    scopus 로고
    • Acetylcholinesterase as an amyloid enhancing factor in PrP82-146 aggregation process
    • Pera M, Martinez-Otero A, Colombo L, Salmona M, Ruiz-Molina D, et al. (2009) Acetylcholinesterase as an amyloid enhancing factor in PrP82-146 aggregation process. Mol Cell Neurosci 40: 217-224.
    • (2009) Mol Cell Neurosci , vol.40 , pp. 217-224
    • Pera, M.1    Martinez-Otero, A.2    Colombo, L.3    Salmona, M.4    Ruiz-Molina, D.5
  • 29
    • 0034284410 scopus 로고    scopus 로고
    • Huperzine A and tacrine attenuate beta-amyloid peptide-induced oxidative injury
    • Xiao XQ, Wang R, Tang XC, (2000) Huperzine A and tacrine attenuate beta-amyloid peptide-induced oxidative injury. J Neurosc Res 61: 564-9.
    • (2000) J Neurosc Res , vol.61 , pp. 564-569
    • Xiao, X.Q.1    Wang, R.2    Tang, X.C.3
  • 30
    • 30144437522 scopus 로고    scopus 로고
    • Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine
    • Wang R, Yan H, Tang XC, (2006) Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine. Acta Pharmacol Sin 27: 1-26.
    • (2006) Acta Pharmacol Sin , vol.27 , pp. 1-26
    • Wang, R.1    Yan, H.2    Tang, X.C.3
  • 31
    • 85027927074 scopus 로고    scopus 로고
    • Effect of huprine X on beta-amyloid, synaptophysin and alpha7 neuronal nicotinic acetylcholine receptors in the brain of 3xTg-AD and APPswe transgenic mice
    • Hedberg MM, Clos MV, Ratia M, Gonzalez D, Lithner CU, et al. (2010) Effect of huprine X on beta-amyloid, synaptophysin and alpha7 neuronal nicotinic acetylcholine receptors in the brain of 3xTg-AD and APPswe transgenic mice. Neurodegener Dis 7: 379-388.
    • (2010) Neurodegener Dis , vol.7 , pp. 379-388
    • Hedberg, M.M.1    Clos, M.V.2    Ratia, M.3    Gonzalez, D.4    Lithner, C.U.5
  • 32
    • 84873087083 scopus 로고    scopus 로고
    • Huprine X and huperzine A improve cognition and regulate some neurochemical processes related with Alzheimer's disease in triple transgenic mice (3xTg-AD)
    • Ratia M, Gimenez-Llort L, Camps P, Muñoz-Torrero D, Perez B, et al. (2013) Huprine X and huperzine A improve cognition and regulate some neurochemical processes related with Alzheimer's disease in triple transgenic mice (3xTg-AD). Neurodegener Dis 11: 129-140.
    • (2013) Neurodegener Dis , vol.11 , pp. 129-140
    • Ratia, M.1    Gimenez-Llort, L.2    Camps, P.3    Muñoz-Torrero, D.4    Perez, B.5
  • 33
    • 2642680857 scopus 로고    scopus 로고
    • Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis
    • Stadelmann C, Bruck W, Bancher C, Jellinger K, Lassmann H, (1998) Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis. J Neuropathol Exp Neurol 57: 456-464.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 456-464
    • Stadelmann, C.1    Bruck, W.2    Bancher, C.3    Jellinger, K.4    Lassmann, H.5
  • 34
    • 17044404593 scopus 로고    scopus 로고
    • Effects of (+/-)-huprine Y and (+/-)-huprine Z, two new anticholinesterasic drugs, on muscarinic receptors
    • Alcala MM, Maderuelo A, Vivas NM, Camps P, Muñoz-Torrero D, et al. (2005) Effects of (+/-)-huprine Y and (+/-)-huprine Z, two new anticholinesterasic drugs, on muscarinic receptors. Neurosci Lett 379: 106-109.
    • (2005) Neurosci Lett , vol.379 , pp. 106-109
    • Alcala, M.M.1    Maderuelo, A.2    Vivas, N.M.3    Camps, P.4    Muñoz-Torrero, D.5
  • 35
    • 0037036219 scopus 로고    scopus 로고
    • Interaction of a new potent anticholinesterasic compound (+/-)huprine X with muscarinic receptors in rat brain
    • Roman S, Vivas NM, Badia A, Clos MV, (2002) Interaction of a new potent anticholinesterasic compound (+/-)huprine X with muscarinic receptors in rat brain. Neurosci Lett 325: 103-106.
    • (2002) Neurosci Lett , vol.325 , pp. 103-106
    • Roman, S.1    Vivas, N.M.2    Badia, A.3    Clos, M.V.4
  • 36
    • 34547136698 scopus 로고    scopus 로고
    • Galantamine postischemia provides neuroprotection and memory recovery against transient global cerebral ischemia in gerbils
    • Lorrio S, Sobrado M, Arias E, Roda JM, Garcia AG, et al. (2007) Galantamine postischemia provides neuroprotection and memory recovery against transient global cerebral ischemia in gerbils. J Pharmacol Exp Ther 322: 591-599.
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 591-599
    • Lorrio, S.1    Sobrado, M.2    Arias, E.3    Roda, J.M.4    Garcia, A.G.5
  • 37
    • 2342420034 scopus 로고    scopus 로고
    • Lipid peroxidation and oxidative imbalance: early functional events in Alzheimer's disease
    • Pratico D, Sung S, (2004) Lipid peroxidation and oxidative imbalance: early functional events in Alzheimer's disease. J Alzheimers Dis 6: 171-175.
    • (2004) J Alzheimers Dis , vol.6 , pp. 171-175
    • Pratico, D.1    Sung, S.2
  • 38
    • 0016830798 scopus 로고
    • Nerve growth factor-induced process formation by cultured rat pheochromocytoma cells
    • Tischler AS, Greene LA, (1975) Nerve growth factor-induced process formation by cultured rat pheochromocytoma cells. Nature 258: 341-342.
    • (1975) Nature , vol.258 , pp. 341-342
    • Tischler, A.S.1    Greene, L.A.2
  • 39
    • 0019506626 scopus 로고
    • Regulation of acetylcholinesterase activity by nerve growth factor. Role of transcription and dissociation from effects on proliferation and neurite outgrowth
    • Greene LA, Rukenstein A, (1981) Regulation of acetylcholinesterase activity by nerve growth factor. Role of transcription and dissociation from effects on proliferation and neurite outgrowth. J Biol Chem 256: 6363-6367.
    • (1981) J Biol Chem , vol.256 , pp. 6363-6367
    • Greene, L.A.1    Rukenstein, A.2
  • 40
    • 18344414746 scopus 로고    scopus 로고
    • The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
    • Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, et al. (1999) The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 38: 7609-7616.
    • (1999) Biochemistry , vol.38 , pp. 7609-7616
    • Huang, X.1    Atwood, C.S.2    Hartshorn, M.A.3    Multhaup, G.4    Goldstein, L.E.5
  • 41
    • 0344688198 scopus 로고    scopus 로고
    • Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors
    • Arias E, Ales E, Gabilan NH, Cano-Abad MF, Villarroya M, et al. (2004) Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors. Neuropharmacology 46: 103-114.
    • (2004) Neuropharmacology , vol.46 , pp. 103-114
    • Arias, E.1    Ales, E.2    Gabilan, N.H.3    Cano-Abad, M.F.4    Villarroya, M.5
  • 42
    • 0035919804 scopus 로고    scopus 로고
    • Hiperzine A protects rat pheochromocytoma cells against oxygen-glucose deprivation
    • Zhou J, Fu Y, Tang XC, (2001) Hiperzine A protects rat pheochromocytoma cells against oxygen-glucose deprivation. NeuroReport 12: 2073-2077.
    • (2001) NeuroReport , vol.12 , pp. 2073-2077
    • Zhou, J.1    Fu, Y.2    Tang, X.C.3
  • 43
    • 0035964415 scopus 로고    scopus 로고
    • Huperzine A attenuates hydrogen peroxide induced apoptosis by regulating expression of apoptosis-related genes in rat PC12 cells
    • Wang R, Xiao XQ, Tang XC, (2001) Huperzine A attenuates hydrogen peroxide induced apoptosis by regulating expression of apoptosis-related genes in rat PC12 cells. Neuroreport 12: 2629-2634.
    • (2001) Neuroreport , vol.12 , pp. 2629-2634
    • Wang, R.1    Xiao, X.Q.2    Tang, X.C.3
  • 44
    • 0037622682 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons
    • Takada Y, Yonezawa A, Kume T, Katsuki H, Kaneko S, et al. (2003) Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons. J Pharmacol Exp Ther 306: 772-777.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 772-777
    • Takada, Y.1    Yonezawa, A.2    Kume, T.3    Katsuki, H.4    Kaneko, S.5
  • 45
    • 33747044365 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade
    • Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Sugimoto H, et al. (2006) Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade. Neuropharmacology 51: 474-486.
    • (2006) Neuropharmacology , vol.51 , pp. 474-486
    • Takada-Takatori, Y.1    Kume, T.2    Sugimoto, M.3    Katsuki, H.4    Sugimoto, H.5
  • 46
    • 27744516086 scopus 로고    scopus 로고
    • Nicotinic-receptor potentiator drugs, huprine X and galantamine, increase ACh release by blocking AChE activity but not acting on nicotinic receptors
    • Roman S, Badia A, Camps P, Muñoz-Torrero D, Clos MV, (2005) Nicotinic-receptor potentiator drugs, huprine X and galantamine, increase ACh release by blocking AChE activity but not acting on nicotinic receptors. Brain Res 1061: 73-79.
    • (2005) Brain Res , vol.1061 , pp. 73-79
    • Roman, S.1    Badia, A.2    Camps, P.3    Muñoz-Torrero, D.4    Clos, M.V.5
  • 47
    • 0036667555 scopus 로고    scopus 로고
    • Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
    • Zelko IN, Mariani TJ, Folz RJ, (2002) Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med 33: 337-349.
    • (2002) Free Radic Biol Med , vol.33 , pp. 337-349
    • Zelko, I.N.1    Mariani, T.J.2    Folz, R.J.3
  • 48
    • 34247178359 scopus 로고    scopus 로고
    • DNA repair in differentiated cells: some new answers to old questions
    • Nouspikel T, (2007) DNA repair in differentiated cells: some new answers to old questions. Neuros 145: 1213-1221.
    • (2007) Neuros , vol.145 , pp. 1213-1221
    • Nouspikel, T.1
  • 49
    • 0034885975 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and neurodegenerative disease
    • Nakamura S, Takahashi T, Yamashita H, Kawakami H, (2001) Nicotinic acetylcholine receptors and neurodegenerative disease. Alcohol 24: 79-81.
    • (2001) Alcohol , vol.24 , pp. 79-81
    • Nakamura, S.1    Takahashi, T.2    Yamashita, H.3    Kawakami, H.4
  • 50
    • 33748960736 scopus 로고    scopus 로고
    • Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity
    • Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Niidome T, et al. (2006) Neuroprotective effects of galanthamine and tacrine against glutamate neurotoxicity. Eur J Pharmacol 549: 19-26.
    • (2006) Eur J Pharmacol , vol.549 , pp. 19-26
    • Takada-Takatori, Y.1    Kume, T.2    Sugimoto, M.3    Katsuki, H.4    Niidome, T.5
  • 51
    • 78649368474 scopus 로고    scopus 로고
    • Structural and functional neuroprotection in glaucoma: role of galantamine-mediated activation of muscarinic acetylcholine receptors
    • Almasieh M, Zhou Y, Kelly ME, Casanova C, Di PA, (2010) Structural and functional neuroprotection in glaucoma: role of galantamine-mediated activation of muscarinic acetylcholine receptors. Cell Death Dis 1: e27.
    • (2010) Cell Death Dis , vol.1
    • Almasieh, M.1    Zhou, Y.2    Kelly, M.E.3    Casanova, C.4    Di, P.A.5
  • 52
    • 33646899542 scopus 로고    scopus 로고
    • Acetyl-L-carnitine protects striatal neurons against in vitro ischemia: the role of endogenous acetylcholine
    • Picconi B, Barone I, Pisani A, Nicolai R, Benatti P, et al. (2006) Acetyl-L-carnitine protects striatal neurons against in vitro ischemia: the role of endogenous acetylcholine. Neuropharmacology 50: 917-923.
    • (2006) Neuropharmacology , vol.50 , pp. 917-923
    • Picconi, B.1    Barone, I.2    Pisani, A.3    Nicolai, R.4    Benatti, P.5
  • 53
    • 62649162799 scopus 로고    scopus 로고
    • Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells
    • Giordano G, Li L, White CC, Farin FM, Wilkerson HW, et al. (2009) Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells. J Neurochem 109: 525-538.
    • (2009) J Neurochem , vol.109 , pp. 525-538
    • Giordano, G.1    Li, L.2    White, C.C.3    Farin, F.M.4    Wilkerson, H.W.5
  • 54
    • 67449155877 scopus 로고    scopus 로고
    • Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: possible behavioural, biochemical and cellular alterations
    • Kumar P, Kumar A, (2009) Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: possible behavioural, biochemical and cellular alterations. Eur J Pharmacol 615: 91-101.
    • (2009) Eur J Pharmacol , vol.615 , pp. 91-101
    • Kumar, P.1    Kumar, A.2
  • 55
    • 0032888723 scopus 로고    scopus 로고
    • Improving effects of huperzine A on abnormal lipid peroxidation and superoxide dismutase in aged rats
    • Shang YZ, Ye JW, Tang XC, (1999) Improving effects of huperzine A on abnormal lipid peroxidation and superoxide dismutase in aged rats. Zhongguo Yao Li Xue Bao 20: 824-828.
    • (1999) Zhongguo Yao Li Xue Bao , vol.20 , pp. 824-828
    • Shang, Y.Z.1    Ye, J.W.2    Tang, X.C.3
  • 56
    • 0036903919 scopus 로고    scopus 로고
    • Huperzine B protects rat pheochromocytoma cells against oxygen-glucose deprivation-induced injury
    • Wang ZF, Zhou J, Tang XC, (2002) Huperzine B protects rat pheochromocytoma cells against oxygen-glucose deprivation-induced injury. Acta Pharmacol Sin 23: 1193-1198.
    • (2002) Acta Pharmacol Sin , vol.23 , pp. 1193-1198
    • Wang, Z.F.1    Zhou, J.2    Tang, X.C.3
  • 57
    • 7244243873 scopus 로고    scopus 로고
    • Regulation of Cu/Zn-superoxide dismutase expression via the phosphatidylinositol 3 kinase/Akt pathway and nuclear factor-kappaB
    • Rojo AI, Salinas M, Martin D, Perona R, Cuadrado A, (2004) Regulation of Cu/Zn-superoxide dismutase expression via the phosphatidylinositol 3 kinase/Akt pathway and nuclear factor-kappaB. J Neurosci 24: 7324-7334.
    • (2004) J Neurosci , vol.24 , pp. 7324-7334
    • Rojo, A.I.1    Salinas, M.2    Martin, D.3    Perona, R.4    Cuadrado, A.5
  • 58
    • 0020315499 scopus 로고
    • Regulation of muscarinic ligand binding sites by nerve growth factor in PC12 phaeochromocytoma cells
    • Jumblatt JE, Tischler AS, (1982) Regulation of muscarinic ligand binding sites by nerve growth factor in PC12 phaeochromocytoma cells. Nature 297: 152-154.
    • (1982) Nature , vol.297 , pp. 152-154
    • Jumblatt, J.E.1    Tischler, A.S.2
  • 59
    • 0020554531 scopus 로고
    • Increased sodium ion conductance through nicotinic acetylcholine receptor channels in PC12 cells exposed to nerve growth factors
    • Amy CM, Bennett EL, (1983) Increased sodium ion conductance through nicotinic acetylcholine receptor channels in PC12 cells exposed to nerve growth factors. J Neurosci 3: 1547-1553.
    • (1983) J Neurosci , vol.3 , pp. 1547-1553
    • Amy, C.M.1    Bennett, E.L.2
  • 60
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T, (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 61
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M, (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 248: 248-254.
    • (1976) Anal Biochem , vol.248 , pp. 248-254
    • Bradford, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.