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Volumn 615, Issue 1-3, 2009, Pages 91-101

Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: Possible behavioural, biochemical and cellular alterations

Author keywords

3 Nitropropionic acid; Huntington's disease; Mitochondrion; Oxidative stress; Rivastigmine

Indexed keywords

3 NITROPROPIONIC ACID; CATALASE; MITOCHONDRIAL COMPLEX II; MITOCHONDRIAL COMPLEX IV; MITOCHONDRIAL ENZYME; NITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RIVASTIGMINE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 67449155877     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.04.058     Document Type: Article
Times cited : (61)

References (63)
  • 1
    • 0032479940 scopus 로고    scopus 로고
    • 3-nitropropionic acid's lethal triplet: cooperative pathways of neurodegeneration
    • Alexi T., Hughes P.E., Faull R.L., and Williams C.E. 3-nitropropionic acid's lethal triplet: cooperative pathways of neurodegeneration. Neuroreport 9 (1998) R57-64
    • (1998) Neuroreport , vol.9
    • Alexi, T.1    Hughes, P.E.2    Faull, R.L.3    Williams, C.E.4
  • 2
    • 10844225168 scopus 로고    scopus 로고
    • Rivastigmine as a modulator of the neuronal glutamate transporter rEAAC1 mRNA expression
    • Andin J., Enz A., Gentsch C., and Marcusson J. Rivastigmine as a modulator of the neuronal glutamate transporter rEAAC1 mRNA expression. Dement. Geriatr. Cogn. Disord. 19 (2005) 18-23
    • (2005) Dement. Geriatr. Cogn. Disord. , vol.19 , pp. 18-23
    • Andin, J.1    Enz, A.2    Gentsch, C.3    Marcusson, J.4
  • 3
    • 0034741573 scopus 로고    scopus 로고
    • Cognitive disorders in patients with Huntington's disease
    • Barquero-Jiménez M.S., and Gómez-Tortosa E. Cognitive disorders in patients with Huntington's disease. Rev. Neurol. 32 (2001) 1067-1071
    • (2001) Rev. Neurol. , vol.32 , pp. 1067-1071
    • Barquero-Jiménez, M.S.1    Gómez-Tortosa, E.2
  • 4
    • 0034237719 scopus 로고    scopus 로고
    • Energetic in the pathogenesis of neurodegenerative disease
    • Beal M.F. Energetic in the pathogenesis of neurodegenerative disease. Trends Neurosci. 23 (2000) 298-304
    • (2000) Trends Neurosci. , vol.23 , pp. 298-304
    • Beal, M.F.1
  • 7
    • 0032763708 scopus 로고    scopus 로고
    • Effect of rivastigmine on scopolamine-induced memory impairment in rats
    • Bejar C., Wang R.H., and Weinstock M. Effect of rivastigmine on scopolamine-induced memory impairment in rats. Eur. J. Pharmacol. 383 (1999) Z31-40
    • (1999) Eur. J. Pharmacol. , vol.383
    • Bejar, C.1    Wang, R.H.2    Weinstock, M.3
  • 8
    • 0032842038 scopus 로고    scopus 로고
    • Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease
    • Berman S.B., and Hastings T.G. Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease. J. Neurochem. 73 (1999) 1127-1137
    • (1999) J. Neurochem. , vol.73 , pp. 1127-1137
    • Berman, S.B.1    Hastings, T.G.2
  • 9
    • 0029565944 scopus 로고
    • Effects of chronic MPTP and 3-nitropropionic acid in nonhuman primates
    • Brouillet E., and Hantraye P. Effects of chronic MPTP and 3-nitropropionic acid in nonhuman primates. Curr. Opin. Neurol. 8 (1995) 469-473
    • (1995) Curr. Opin. Neurol. , vol.8 , pp. 469-473
    • Brouillet, E.1    Hantraye, P.2
  • 10
    • 0032815680 scopus 로고    scopus 로고
    • Replicating Huntington's disease phenotype in experimental animals
    • Brouillet E., Condé F., Beal M.F., and Hantraye P. Replicating Huntington's disease phenotype in experimental animals. Prog. Neurobiol. 59 (1999) 427-468
    • (1999) Prog. Neurobiol. , vol.59 , pp. 427-468
    • Brouillet, E.1    Condé, F.2    Beal, M.F.3    Hantraye, P.4
  • 11
  • 12
    • 0037437598 scopus 로고    scopus 로고
    • Cholinesterase inhibitor rivastigmine enhance the mitochondrial electron transport chain in lymphocytes of patients with Alzheimer's disease
    • Casademont J., Miró O., Rodriguez-Santiago B., Viedma P., Blesa R., and Cardellach F. Cholinesterase inhibitor rivastigmine enhance the mitochondrial electron transport chain in lymphocytes of patients with Alzheimer's disease. J. Neurol. Sci. 206 (2003) 23-26
    • (2003) J. Neurol. Sci. , vol.206 , pp. 23-26
    • Casademont, J.1    Miró, O.2    Rodriguez-Santiago, B.3    Viedma, P.4    Blesa, R.5    Cardellach, F.6
  • 13
    • 0032904412 scopus 로고    scopus 로고
    • An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration
    • Cassarino D.S., and Bennett Jr. J.P. An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration. Brain Res. Rev. 29 (1999) 1-25
    • (1999) Brain Res. Rev. , vol.29 , pp. 1-25
    • Cassarino, D.S.1    Bennett Jr., J.P.2
  • 14
    • 36148947831 scopus 로고    scopus 로고
    • A rivastigmine patch for the treatment of Alzheimer's disease and Parkinson's disease dementia
    • Cummings J., and Winblad B. A rivastigmine patch for the treatment of Alzheimer's disease and Parkinson's disease dementia. Expert. Rev. Neurother. 7 (2007) 1457-1463
    • (2007) Expert. Rev. Neurother. , vol.7 , pp. 1457-1463
    • Cummings, J.1    Winblad, B.2
  • 15
  • 18
    • 38549149803 scopus 로고    scopus 로고
    • Systematic review of the effectiveness of rivastigmine for the treatment of behavioral disturbances in dementia and other neurological disorders
    • Figiel G., and Sadowsky C.A. Systematic review of the effectiveness of rivastigmine for the treatment of behavioral disturbances in dementia and other neurological disorders. Curr. Med. Res. Opin. 24 (2008) 157-166
    • (2008) Curr. Med. Res. Opin. , vol.24 , pp. 157-166
    • Figiel, G.1    Sadowsky, C.A.2
  • 19
    • 0035686083 scopus 로고    scopus 로고
    • Phenolic anti-inflammatory antioxidant reversal of Ab-induced cognitive deficits and neuropathology
    • Frautschy S.A., Hu W., Kim P., Miller S.A., White-Harris M.E., Chua T., and Cole G.M. Phenolic anti-inflammatory antioxidant reversal of Ab-induced cognitive deficits and neuropathology. Neurobiol. Aging 22 (2001) 993-1005
    • (2001) Neurobiol. Aging , vol.22 , pp. 993-1005
    • Frautschy, S.A.1    Hu, W.2    Kim, P.3    Miller, S.A.4    White-Harris, M.E.5    Chua, T.6    Cole, G.M.7
  • 20
    • 0028955008 scopus 로고
    • 3-Nitropropionic acid produces indirect excitotoxic damage to rat striatum
    • Fu Y., He F., Zhang S., Huang J., Zhang J., and Jiao X. 3-Nitropropionic acid produces indirect excitotoxic damage to rat striatum. Neurotoxicol. Teratol. 17 (1995) 333-339
    • (1995) Neurotoxicol. Teratol. , vol.17 , pp. 333-339
    • Fu, Y.1    He, F.2    Zhang, S.3    Huang, J.4    Zhang, J.5    Jiao, X.6
  • 21
    • 33645855623 scopus 로고    scopus 로고
    • Huperzine A attenuates mitochondrial dysfunction in beta-amyloid-treated PC12 cells by reducing oxygen free radicals accumulation and improving mitochondrial energy metabolism
    • Gao X., and Tang X.C. Huperzine A attenuates mitochondrial dysfunction in beta-amyloid-treated PC12 cells by reducing oxygen free radicals accumulation and improving mitochondrial energy metabolism. J. Neurosci. Res. 83 (2006) 1048-1057
    • (2006) J. Neurosci. Res. , vol.83 , pp. 1048-1057
    • Gao, X.1    Tang, X.C.2
  • 22
    • 45149107487 scopus 로고    scopus 로고
    • Mechanisms of neurodegeneration in Huntington's disease
    • Gil J.M., and Rego A.C. Mechanisms of neurodegeneration in Huntington's disease. Eur. J. Neurosci. 27 (2008) 2803-2820
    • (2008) Eur. J. Neurosci. , vol.27 , pp. 2803-2820
    • Gil, J.M.1    Rego, A.C.2
  • 23
    • 29744466425 scopus 로고
    • Determination of serum proteins by means of the biuret reaction
    • Gornall A.G., Bardawill C.J., and David M.M. Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 177 (1949) 751-766
    • (1949) J. Biol. Chem. , vol.177 , pp. 751-766
    • Gornall, A.G.1    Bardawill, C.J.2    David, M.M.3
  • 25
    • 47849119964 scopus 로고    scopus 로고
    • Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysis
    • Hansen R.A., Gartlehner G., Webb A.P., Morgan L.C., Moore C.G., and Jonas D.E. Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysis. Clin. Interv. Aging 3 (2008) 211-225
    • (2008) Clin. Interv. Aging , vol.3 , pp. 211-225
    • Hansen, R.A.1    Gartlehner, G.2    Webb, A.P.3    Morgan, L.C.4    Moore, C.G.5    Jonas, D.E.6
  • 26
    • 0033985927 scopus 로고    scopus 로고
    • Rivastigmine, a new-generation cholinesterase inhibitor for the treatment of Alzheimer's disease
    • Jann M.W. Rivastigmine, a new-generation cholinesterase inhibitor for the treatment of Alzheimer's disease. Pharmacotherapy 20 (2000) 1-12
    • (2000) Pharmacotherapy , vol.20 , pp. 1-12
    • Jann, M.W.1
  • 27
    • 0034799214 scopus 로고    scopus 로고
    • A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease
    • Keene C.D., Rodrigues C.M., Eich T., Linehan-Stieers C., Abt A., Kren B.T., Steer C.J., and Low W.C. A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease. Exp. Neurol. 171 (2001) 351-360
    • (2001) Exp. Neurol. , vol.171 , pp. 351-360
    • Keene, C.D.1    Rodrigues, C.M.2    Eich, T.3    Linehan-Stieers, C.4    Abt, A.5    Kren, B.T.6    Steer, C.J.7    Low, W.C.8
  • 28
    • 38649128178 scopus 로고    scopus 로고
    • Acetylcholine inhibits long-term hypoxia-induced apoptosis by suppressing the oxidative stress-mediated MAPKs activation as well as regulation of Bcl-2, c-IAPs, and caspase-3 in mouse embryonic stem cells
    • Kim M.H., Kim M.O., Heo J.S., Kim J.S., and Han H.J. Acetylcholine inhibits long-term hypoxia-induced apoptosis by suppressing the oxidative stress-mediated MAPKs activation as well as regulation of Bcl-2, c-IAPs, and caspase-3 in mouse embryonic stem cells. Apoptosis 13 (2008) 295-304
    • (2008) Apoptosis , vol.13 , pp. 295-304
    • Kim, M.H.1    Kim, M.O.2    Heo, J.S.3    Kim, J.S.4    Han, H.J.5
  • 29
    • 0000161966 scopus 로고
    • Colorimetric estimation of lactate dehydrogenase
    • King J. Colorimetric estimation of lactate dehydrogenase. J. Med. Lab. Technol. 16 (1959) 256-261
    • (1959) J. Med. Lab. Technol. , vol.16 , pp. 256-261
    • King, J.1
  • 30
    • 77956987911 scopus 로고
    • Preparation of succinate dehydrogenase and reconstitution of succinate oxidase
    • King T.E. Preparation of succinate dehydrogenase and reconstitution of succinate oxidase. Methods Enzymol. 10 (1967) 322-331
    • (1967) Methods Enzymol. , vol.10 , pp. 322-331
    • King, T.E.1
  • 31
    • 77956999492 scopus 로고
    • Preparations and properties of soluble NADH dehydrogenases from cardiac muscle
    • King T.E., and Howard R.L. Preparations and properties of soluble NADH dehydrogenases from cardiac muscle. Methods Enzymol. 10 (1967) 275-294
    • (1967) Methods Enzymol. , vol.10 , pp. 275-294
    • King, T.E.1    Howard, R.L.2
  • 32
    • 0017804313 scopus 로고
    • Generation of superoxide radical during auto-oxidation of hydroxylamine and an assay of superoxide dismutase
    • Kono Y. Generation of superoxide radical during auto-oxidation of hydroxylamine and an assay of superoxide dismutase. Arch. Biochem. Biophy. 186 (1978) 189-195
    • (1978) Arch. Biochem. Biophy. , vol.186 , pp. 189-195
    • Kono, Y.1
  • 34
    • 33748310632 scopus 로고    scopus 로고
    • Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms
    • Kumar P., Padi S.S., Naidu P.S., and Kumar A. Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms. Behav. Pharmacol. 17 (2006) 485-492
    • (2006) Behav. Pharmacol. , vol.17 , pp. 485-492
    • Kumar, P.1    Padi, S.S.2    Naidu, P.S.3    Kumar, A.4
  • 35
    • 33947377439 scopus 로고    scopus 로고
    • Possible neuroprotective mechanisms of curcumin in attenuating 3-nitropropionic acid-induced neurotoxicity
    • Kumar P., Padi S.S., Naidu P.S., and Kumar A. Possible neuroprotective mechanisms of curcumin in attenuating 3-nitropropionic acid-induced neurotoxicity. Methods Find. Exp. Clin. Pharmacol. 29 (2007) 1-7
    • (2007) Methods Find. Exp. Clin. Pharmacol. , vol.29 , pp. 1-7
    • Kumar, P.1    Padi, S.S.2    Naidu, P.S.3    Kumar, A.4
  • 36
    • 41949126549 scopus 로고    scopus 로고
    • Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease
    • Lim D., Fedrizzi L., Tartari M., Zuccato C., Cattaneo E., Brini M., and Carafoli E. Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease. J. Biol. Chem. 283 (2008) 5780-5789
    • (2008) J. Biol. Chem. , vol.283 , pp. 5780-5789
    • Lim, D.1    Fedrizzi, L.2    Tartari, M.3    Zuccato, C.4    Cattaneo, E.5    Brini, M.6    Carafoli, E.7
  • 37
    • 0026876637 scopus 로고
    • Studies on the epidemiology and etiology of moldy sugarcane poisoning in China
    • Liu X., Luo X., and Hu W. Studies on the epidemiology and etiology of moldy sugarcane poisoning in China. Biomed. Environ. Sci. 5 (1992) 161-177
    • (1992) Biomed. Environ. Sci. , vol.5 , pp. 161-177
    • Liu, X.1    Luo, X.2    Hu, W.3
  • 38
    • 0002191974 scopus 로고
    • Catalase
    • Bergmeyer H.U. (Ed), Academic Press, New York
    • Luck H. Catalase. In: Bergmeyer H.U. (Ed). Methods of Enzymatic Analysis (1971), Academic Press, New York 885-893
    • (1971) Methods of Enzymatic Analysis , pp. 885-893
    • Luck, H.1
  • 39
    • 0015897057 scopus 로고
    • Choline acetylase and glutamic acid decarboxylase in Huntington's chorea
    • McGeer P.L., McGeer E.G., and Fibiger H.C. Choline acetylase and glutamic acid decarboxylase in Huntington's chorea. Neurology 23 (1973) 912-918
    • (1973) Neurology , vol.23 , pp. 912-918
    • McGeer, P.L.1    McGeer, E.G.2    Fibiger, H.C.3
  • 40
    • 0029098675 scopus 로고
    • Moldy sugarcane poisoning-a case report with a brief review
    • Ming L. Moldy sugarcane poisoning-a case report with a brief review. J. Toxicol. Clin. Toxicol. 33 (1995) 363-367
    • (1995) J. Toxicol. Clin. Toxicol. , vol.33 , pp. 363-367
    • Ming, L.1
  • 41
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55-63
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 42
    • 20144376099 scopus 로고    scopus 로고
    • Melatonin protects against neuronal damage induced by 3-nitropropionic acid in rat striatum
    • Nam E., Lee S.M., Koh S.E., Joo W.S., Maeng S., Im H.I., and Kim Y.S. Melatonin protects against neuronal damage induced by 3-nitropropionic acid in rat striatum. Brain Res. 1046 (2005) 90-96
    • (2005) Brain Res. , vol.1046 , pp. 90-96
    • Nam, E.1    Lee, S.M.2    Koh, S.E.3    Joo, W.S.4    Maeng, S.5    Im, H.I.6    Kim, Y.S.7
  • 43
    • 0033971898 scopus 로고    scopus 로고
    • Mitochondria and neuronal survival
    • Nicholls D.G., and Budd S.L. Mitochondria and neuronal survival. Physiol. Rev. 80 (2000) 315-360
    • (2000) Physiol. Rev. , vol.80 , pp. 315-360
    • Nicholls, D.G.1    Budd, S.L.2
  • 44
    • 37549040877 scopus 로고    scopus 로고
    • Effects of rivastigmine on tremor and other motor symptoms in patients with Parkinson's disease dementia: a retrospective analysis of a double-blind trial and an open-label extension
    • Oertel W., Poewe W., Wolters E., De Deyn P.P., Emre M., Kirsch C., Hsu C., Tekin S., and Lane R. Effects of rivastigmine on tremor and other motor symptoms in patients with Parkinson's disease dementia: a retrospective analysis of a double-blind trial and an open-label extension. Drug Safety 31 (2008) 79-94
    • (2008) Drug Safety , vol.31 , pp. 79-94
    • Oertel, W.1    Poewe, W.2    Wolters, E.3    De Deyn, P.P.4    Emre, M.5    Kirsch, C.6    Hsu, C.7    Tekin, S.8    Lane, R.9
  • 45
    • 0344010051 scopus 로고    scopus 로고
    • Rivastigmine blocks voltage-activated K currents in dissociated rat hippocampal neurons
    • Pan Y., Xu X., and Wang X. Rivastigmine blocks voltage-activated K currents in dissociated rat hippocampal neurons. Br. J. Pharmacol. 140 (2003) 907-912
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 907-912
    • Pan, Y.1    Xu, X.2    Wang, X.3
  • 46
    • 42149142899 scopus 로고    scopus 로고
    • Memantine MEM-MD-12 Study Group. Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial
    • Porsteinsson A.P., Grossberg G.T., Mintzer J., and Olin J.T. Memantine MEM-MD-12 Study Group. Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial. Curr. Alzheimer Res. 5 (2008) 83-89
    • (2008) Curr. Alzheimer Res. , vol.5 , pp. 83-89
    • Porsteinsson, A.P.1    Grossberg, G.T.2    Mintzer, J.3    Olin, J.T.4
  • 47
    • 0032551572 scopus 로고    scopus 로고
    • Possible role of nitric oxide in the nootropic and antiamnesic effects of neurosteroids on aging and dizociline induced leaning impairment
    • Reddy D.S., and Kulkarni S.K. Possible role of nitric oxide in the nootropic and antiamnesic effects of neurosteroids on aging and dizociline induced leaning impairment. Brain Res. 799 (1998) 215-219
    • (1998) Brain Res. , vol.799 , pp. 215-219
    • Reddy, D.S.1    Kulkarni, S.K.2
  • 49
    • 34547760490 scopus 로고    scopus 로고
    • Treatment of Alzheimer's disease across the spectrum of severity
    • Shah S., and Reichman W.E. Treatment of Alzheimer's disease across the spectrum of severity. Clin. Interv. Aging. 1 (2006) 131-142
    • (2006) Clin. Interv. Aging. , vol.1 , pp. 131-142
    • Shah, S.1    Reichman, W.E.2
  • 50
    • 0034717594 scopus 로고    scopus 로고
    • Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats
    • Shear D.A., Haik K.L., and Dunbar G.L. Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats. Neuroreport 11 (2000) 1833-7183
    • (2000) Neuroreport , vol.11 , pp. 1833-7183
    • Shear, D.A.1    Haik, K.L.2    Dunbar, G.L.3
  • 51
    • 33748523002 scopus 로고    scopus 로고
    • Rivastigmine: in Parkinson's disease dementia
    • Siddiqui M., Asif A., Wagstaff, and Antona J. Rivastigmine: in Parkinson's disease dementia. CNS Drugs 20 (2006) 739-747
    • (2006) CNS Drugs , vol.20 , pp. 739-747
    • Siddiqui, M.1    Asif, A.2    Wagstaff3    Antona, J.4
  • 53
    • 0014059118 scopus 로고
    • An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study
    • Sottocasa G.L., Kuylenstierna B., Ernster L., and Bergstrand A. An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study. J. Cell Biol. 32 (1967) 415-438
    • (1967) J. Cell Biol. , vol.32 , pp. 415-438
    • Sottocasa, G.L.1    Kuylenstierna, B.2    Ernster, L.3    Bergstrand, A.4
  • 54
    • 0038606550 scopus 로고    scopus 로고
    • Neuropathological and behavioral changes induced by various treatment paradigms with MPTP and 3-nitropropionic acid in mice: towards a model of striatonigral degeneration (multiple system atrophy)
    • Stefanova N., Puschban Z., Fernagut P.O., Brouillet E., Tison F., Reindl M., Jellinger K.A., Poewe W., and Wenning G.K. Neuropathological and behavioral changes induced by various treatment paradigms with MPTP and 3-nitropropionic acid in mice: towards a model of striatonigral degeneration (multiple system atrophy). Acta Neuropathol. 106 (2003) 157-166
    • (2003) Acta Neuropathol. , vol.106 , pp. 157-166
    • Stefanova, N.1    Puschban, Z.2    Fernagut, P.O.3    Brouillet, E.4    Tison, F.5    Reindl, M.6    Jellinger, K.A.7    Poewe, W.8    Wenning, G.K.9
  • 55
    • 0035898261 scopus 로고    scopus 로고
    • Behavioural correlates of striatal glial fibrillary acidic protein in the 3-nitropropionic acid rat model: disturbed walking pattern and spatial orientation
    • Teunissen C.E., Steinbusch H.W., Angevaren M., Appels M., de Bruijn C., Prickaerts J., and de Vente J. Behavioural correlates of striatal glial fibrillary acidic protein in the 3-nitropropionic acid rat model: disturbed walking pattern and spatial orientation. Neuroscience 105 (2001) 153-167
    • (2001) Neuroscience , vol.105 , pp. 153-167
    • Teunissen, C.E.1    Steinbusch, H.W.2    Angevaren, M.3    Appels, M.4    de Bruijn, C.5    Prickaerts, J.6    de Vente, J.7
  • 56
    • 34247158550 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases
    • Trushina E., and McMurray C.T. Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases. Neuroscience 145 (2007) 1233-1248
    • (2007) Neuroscience , vol.145 , pp. 1233-1248
    • Trushina, E.1    McMurray, C.T.2
  • 59
    • 30344432706 scopus 로고    scopus 로고
    • Role of mitochondrial DNA in toxic responses to oxidative stress
    • Van Houten B., Woshner V., and Santos J.H. Role of mitochondrial DNA in toxic responses to oxidative stress. DNA Repair (Amst) 5 (2006) 145-152
    • (2006) DNA Repair (Amst) , vol.5 , pp. 145-152
    • Van Houten, B.1    Woshner, V.2    Santos, J.H.3
  • 60
    • 0013914976 scopus 로고
    • Mechanism of lipid peroxide formation in animal
    • Wills E.D. Mechanism of lipid peroxide formation in animal. Biochem. J. 99 (1966) 667-676
    • (1966) Biochem. J. , vol.99 , pp. 667-676
    • Wills, E.D.1
  • 61
    • 0034625561 scopus 로고    scopus 로고
    • Protective effects of huperzine A on beta-amyloid (25-35) induced oxidative injury in rat pheochromocytoma cells
    • Xiao X.Q., Wang R., Han Y.F., and Tang X.C. Protective effects of huperzine A on beta-amyloid (25-35) induced oxidative injury in rat pheochromocytoma cells. Neurosci. Lett. 286 (2000) 155-168
    • (2000) Neurosci. Lett. , vol.286 , pp. 155-168
    • Xiao, X.Q.1    Wang, R.2    Han, Y.F.3    Tang, X.C.4
  • 62
    • 0034284410 scopus 로고    scopus 로고
    • Huperzine A and tacrine attenuate beta-amyloid peptide-induced oxidative injury
    • Xiao X.Q., Wang R., and Tang X.C. Huperzine A and tacrine attenuate beta-amyloid peptide-induced oxidative injury. J. Neurosci. Res. 61 (2000) 564-579
    • (2000) J. Neurosci. Res. , vol.61 , pp. 564-579
    • Xiao, X.Q.1    Wang, R.2    Tang, X.C.3
  • 63
    • 0029550090 scopus 로고
    • Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade
    • Zeevalk G.D., Derr-Yellin E., and Nicklas W.J. Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade. J. Pharmacol. Exp. Ther. 275 (1995) 1124-1130
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 1124-1130
    • Zeevalk, G.D.1    Derr-Yellin, E.2    Nicklas, W.J.3


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