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Volumn 46, Issue 1, 2004, Pages 95-102

Potentiation effects of (±)huprine X, a new acetylcholinesterase inhibitor, on nicotinic receptors in rat cortical synaptosomes

Author keywords

( )Huprine X; Acetylcholinesterase inhibitors; Galantamine; Nicotinic receptors; Physostigmine; Synaptosomes

Indexed keywords

ACETYLCHOLINE; CHOLINESTERASE INHIBITOR; GALANTAMINE; HUPRINE X; MECAMYLAMINE; NICOTINIC RECEPTOR; PHYSOSTIGMINE; TRITIUM; UNCLASSIFIED DRUG; AMINOQUINOLINE DERIVATIVE; FUSED HETEROCYCLIC RINGS; NICOTINIC RECEPTOR BLOCKING AGENT;

EID: 0344256513     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2003.08.005     Document Type: Article
Times cited : (22)

References (32)
  • 2
    • 0033118561 scopus 로고    scopus 로고
    • Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices
    • Alkondon M., Pereira E.F., Eisenberg H.M., Albuquerque E.X. Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices. Journal of Neuroscience. 19:1999;2705.
    • (1999) Journal of Neuroscience , vol.19 , pp. 2705
    • Alkondon, M.1    Pereira, E.F.2    Eisenberg, H.M.3    Albuquerque, E.X.4
  • 3
    • 0032054003 scopus 로고    scopus 로고
    • Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease
    • Badia A., Baños J.E., Camps P. Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease. Bioorganics and Medicinal Chemistry. 6:1998;427-440.
    • (1998) Bioorganics and Medicinal Chemistry , vol.6 , pp. 427-440
    • Badia, A.1    Baños, J.E.2    Camps, P.3
  • 4
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • Bartus R.T., Dean R.L., Beer B., Lippa A.S. The cholinergic hypothesis of geriatric memory dysfunction. Science. 217:1984;408-417.
    • (1984) Science , vol.217 , pp. 408-417
    • Bartus, R.T.1    Dean, R.L.2    Beer, B.3    Lippa, A.S.4
  • 5
    • 0032478778 scopus 로고    scopus 로고
    • Is there a rationale for the use of acetylcholinesterase inhibitors in the therapy of Alzheimer's disease?
    • Benzi G., Moretti A. Is there a rationale for the use of acetylcholinesterase inhibitors in the therapy of Alzheimer's disease? European Journal of Pharmacology. 346:1998;1-13.
    • (1998) European Journal of Pharmacology , vol.346 , pp. 1-13
    • Benzi, G.1    Moretti, A.2
  • 8
    • 0032101015 scopus 로고    scopus 로고
    • Comparative studies of Huperzine A, E2020 and tacrine on behavior and cholinesterase activities
    • Cheng D.H., Tang X.C. Comparative studies of Huperzine A, E2020 and tacrine on behavior and cholinesterase activities. Pharmacological Biochemistry Behavior. 60:1998;377-386.
    • (1998) Pharmacological Biochemistry Behavior , vol.60 , pp. 377-386
    • Cheng, D.H.1    Tang, X.C.2
  • 9
    • 0003600798 scopus 로고    scopus 로고
    • Neurobiología y biología molecular de la enfermedad de Alzheimer
    • DeKosky S.T., López O.L. Neurobiología y biología molecular de la enfermedad de Alzheimer. Revista Neurológica. 27:1998;s.
    • (1998) Revista Neurológica , vol.27
    • Dekosky, S.T.1    López, O.L.2
  • 10
    • 0035025651 scopus 로고    scopus 로고
    • Superfusion of synaptosomes to study presynaptic mechanisms involved in neurotransmitter release from rat brain
    • García-Sanz A., Badia A., Clos M.V. Superfusion of synaptosomes to study presynaptic mechanisms involved in neurotransmitter release from rat brain. Brain Research Protocols. 7:2001;94-102.
    • (2001) Brain Research Protocols , vol.7 , pp. 94-102
    • García-Sanz, A.1    Badia, A.2    Clos, M.V.3
  • 11
    • 0032078728 scopus 로고    scopus 로고
    • Invited review cholinesterase inhibitor for Alzheimer's disease therapy: From tacrine to future applications
    • Giacobini E. Invited review cholinesterase inhibitor for Alzheimer's disease therapy: from tacrine to future applications. Neurochemistry International. 32:1998;413-419.
    • (1998) Neurochemistry International , vol.32 , pp. 413-419
    • Giacobini, E.1
  • 12
    • 73049155988 scopus 로고
    • The isolation of nerve endings from brain: An electron-microscopic study of cell fragments derived by homogenization and centrifugation
    • Gray E.G., Whittaker V.P. The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. Journal of Anatomy. 96:1962;79-88.
    • (1962) Journal of Anatomy , vol.96 , pp. 79-88
    • Gray, E.G.1    Whittaker, V.P.2
  • 13
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • Johnson J.W., Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 325:1987;529-531.
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 14
    • 0034732104 scopus 로고    scopus 로고
    • Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease
    • Maelicke A., Albuquerque E.X. Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease. European Journal of Pharmacology. 393:2000;165-170.
    • (2000) European Journal of Pharmacology , vol.393 , pp. 165-170
    • Maelicke, A.1    Albuquerque, E.X.2
  • 15
    • 0033845742 scopus 로고    scopus 로고
    • Allosterically potentiating ligands of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease
    • Maelicke A., Schrattenholz A., Samochocki M., Radina M., Albuquerque E.X. Allosterically potentiating ligands of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease. Behavioural Brain Research. 113:2000;199-206.
    • (2000) Behavioural Brain Research , vol.113 , pp. 199-206
    • Maelicke, A.1    Schrattenholz, A.2    Samochocki, M.3    Radina, M.4    Albuquerque, E.X.5
  • 17
    • 0029823245 scopus 로고    scopus 로고
    • Nicotinic autoreceptors mediating enhancement of acetylcholine release become operative in conditions of "impaired" cholinergic presynaptic function
    • Marchi M., Raiteri M. Nicotinic autoreceptors mediating enhancement of acetylcholine release become operative in conditions of "impaired" cholinergic presynaptic function. Journal of Neurochemistry. 67:1996;1974-1981.
    • (1996) Journal of Neurochemistry , vol.67 , pp. 1974-1981
    • Marchi, M.1    Raiteri, M.2
  • 18
    • 0032589299 scopus 로고    scopus 로고
    • α4 but not α3 and α7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease
    • Martín-Ruiz C.M., Court J.A., Molnar E., Lee M. α4 but not α3 and α7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease. Journal of Neurochemistry. 73:1999;1635-1640.
    • (1999) Journal of Neurochemistry , vol.73 , pp. 1635-1640
    • Martín-Ruiz, C.M.1    Court, J.A.2    Molnar, E.3    Lee, M.4
  • 19
    • 0024347735 scopus 로고
    • Modulation of excitatory amino acid receptors by groups IIB metal cations in cultured mouse hippocampal neurons
    • Mayer M.L., Vyklicky L. Jr., Westbrook G.L. Modulation of excitatory amino acid receptors by groups IIB metal cations in cultured mouse hippocampal neurons. Journal of Physiology. 415:1989;329-350.
    • (1989) Journal of Physiology , vol.415 , pp. 329-350
    • Mayer, M.L.1    Vyklicky Jr., L.2    Westbrook, G.L.3
  • 20
    • 0023611370 scopus 로고
    • Do tetrahydroaminoacridine (THA) and physostigmine restore acetylcholine release in Alzheimer brains via nicotinic receptors?
    • Nilsson L., Adem A., Hardy J., Winblad B., Nordberg A. Do tetrahydroaminoacridine (THA) and physostigmine restore acetylcholine release in Alzheimer brains via nicotinic receptors? Journal of Neuronal Transmission. 70:1987;357-368.
    • (1987) Journal of Neuronal Transmission , vol.70 , pp. 357-368
    • Nilsson, L.1    Adem, A.2    Hardy, J.3    Winblad, B.4    Nordberg, A.5
  • 21
    • 0015944309 scopus 로고
    • A simple apparatus for studying the release of neurotransmitters from synaptosomes
    • Raiteri M., Angelini F. A simple apparatus for studying the release of neurotransmitters from synaptosomes. European Journal of Pharmacology. 25:1974;411-414.
    • (1974) European Journal of Pharmacology , vol.25 , pp. 411-414
    • Raiteri, M.1    Angelini, F.2
  • 22
    • 0037036219 scopus 로고    scopus 로고
    • Interaction of a new potent anticholinesterasic compound, (±)Huprine X with muscarinic receptors in rat brain
    • Román S., Vivas N.M., Badia A., Clos M.V. Interaction of a new potent anticholinesterasic compound, (±)Huprine X with muscarinic receptors in rat brain. Neuroscience letters. 325:2002;103-106.
    • (2002) Neuroscience letters , vol.325 , pp. 103-106
    • Román, S.1    Vivas, N.M.2    Badia, A.3    Clos, M.V.4
  • 23
    • 0034937463 scopus 로고    scopus 로고
    • Effects of bis(7)-tacrine on spontaneous synaptic activity and on the nicotinic ACh receptor of Torpedo electric organ
    • Ros E., Aleu J., Gómez de Aranda I., Cantí C., Pang Y.P., Marsal J., Solsona C. Effects of bis(7)-tacrine on spontaneous synaptic activity and on the nicotinic ACh receptor of Torpedo electric organ. Journal of Neurophysiology. 86:2001;183-189.
    • (2001) Journal of Neurophysiology , vol.86 , pp. 183-189
    • Ros, E.1    Aleu, J.2    Gómez De Aranda, I.3    Cantí, C.4    Pang, Y.P.5    Marsal, J.6    Solsona, C.7
  • 24
    • 0002457462 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors in Alzheimer's disease
    • Schöder H., Wevers A. Nicotinic acetylcholine receptors in Alzheimer's disease. Alzheimer's Disease Reviews. 3:1998;20-27.
    • (1998) Alzheimer's Disease Reviews , vol.3 , pp. 20-27
    • Schöder, H.1    Wevers, A.2
  • 25
    • 0030023684 scopus 로고    scopus 로고
    • Agonist responses of neural nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands
    • Schrattenholz A., Pereira E.F., Roth U., Weber K.H., Albuquerque E.X., Maelicke A. Agonist responses of neural nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands. Molecular Pharmacology. 49:1996;1-6.
    • (1996) Molecular Pharmacology , vol.49 , pp. 1-6
    • Schrattenholz, A.1    Pereira, E.F.2    Roth, U.3    Weber, K.H.4    Albuquerque, E.X.5    Maelicke, A.6
  • 27
    • 0001228360 scopus 로고    scopus 로고
    • Pharmacological profile of huperzine A, a novel acetylcholinesterase inhibitor from Chinese herb
    • Tang X.C., Han Y.F. Pharmacological profile of huperzine A, a novel acetylcholinesterase inhibitor from Chinese herb. CNS Drug Reviews. 5:1999;281-300.
    • (1999) CNS Drug Reviews , vol.5 , pp. 281-300
    • Tang, X.C.1    Han, Y.F.2
  • 28
    • 0027360360 scopus 로고
    • Physostigmine block of ion channels activated by acetylcholine in BC3H1 cells
    • Wachtel R.E. Physostigmine block of ion channels activated by acetylcholine in BC3H1 cells. Molecular Pharmacology. 44:1993;1051-1055.
    • (1993) Molecular Pharmacology , vol.44 , pp. 1051-1055
    • Wachtel, R.E.1
  • 29
    • 0033845741 scopus 로고    scopus 로고
    • Nicotinic modulation in an animal model of a form of associative learning impaired in Alzheimer's disease
    • Woodruff-Pak D.S., Santos I.S. Nicotinic modulation in an animal model of a form of associative learning impaired in Alzheimer's disease. Behavior Brain Research. 113:2000;11-19.
    • (2000) Behavior Brain Research , vol.113 , pp. 11-19
    • Woodruff-Pak, D.S.1    Santos, I.S.2
  • 30
    • 0033047491 scopus 로고    scopus 로고
    • Physostigmine and atropine potentiate and inhibit neuronal α4β4 nicotinic receptors
    • Zwart R., van Kleef R. Physostigmine and atropine potentiate and inhibit neuronal α4β4 nicotinic receptors. Annals of the New York Academy of Sciences. 886:1999;636-839.
    • (1999) Annals of the New York Academy of Sciences , vol.886 , pp. 636-839
    • Zwart, R.1    Van Kleef, R.2
  • 31
    • 0030842275 scopus 로고    scopus 로고
    • Potentiation and inhibition of neuronal nicotinic receptors by atropine: Competitive and no competitive effects
    • Zwart R., Vijverberg H. Potentiation and inhibition of neuronal nicotinic receptors by atropine: competitive and no competitive effects. Molecular Pharmacology. 52:1997;886-895.
    • (1997) Molecular Pharmacology , vol.52 , pp. 886-895
    • Zwart, R.1    Vijverberg, H.2
  • 32
    • 0034732163 scopus 로고    scopus 로고
    • Potentiation and inhibition of neural α4β2 nicotinic acetylcholine receptors by choline
    • Zwart R., Vijverberg H. Potentiation and inhibition of neural α4β2 nicotinic acetylcholine receptors by choline. European Journal of Pharmacology. 393:2000;209-214.
    • (2000) European Journal of Pharmacology , vol.393 , pp. 209-214
    • Zwart, R.1    Vijverberg, H.2


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