A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway

Biochemical Pharmacology

Volumn 86, Issue 1, 2013, Pages 56-66

  Mazein, Alexander ^a,c   Watterson, Steven ^a   Hsieh, Wei Yuan ^a   Griffiths, William J ^b   Ghazal, Peter ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b SWANSEA UNIVERSITY   (United Kingdom)

^c OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY   (Japan)

Author keywords

Cholesterol; Metabolic network; Pathway map; SBGN; Sterol

Indexed keywords

25 EPOXYCHOLESTEROL; 7 DEHYDROCHOLESTEROL; ACETYL COENZYME A ACETYLTRANSFERASE; CHOLESTANETRIOL 26 MONOOXYGENASE; CYTOCHROME P450; FARNESYL TRANS TRANSFERASE; GERANYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A LYASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; ISOPENTENYL DIPHOSPHATE DELTA ISOMERASE; LANOSTEROL SYNTHASE; MEVALONATE KINASE; MEVALONIC ACID; PHOSPHOMEVALONATE KINASE; SQUALENE MONOOXYGENASE; SQUALENE SYNTHASE; STEROL; STEROL 14ALPHA DEMETHYLASE; TESTOSTERONE 17BETA DEHYDROGENASE; UNCLASSIFIED DRUG; 24,25 EPOXYCHOLESTEROL; 24,25-EPOXYCHOLESTEROL; CHOLESTEROL; DRUG DERIVATIVE; SQUALENE;

AMINO ACID SEQUENCE; ARTICLE; CELLULAR DISTRIBUTION; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; COMPUTER PROGRAM; CYTOPLASM; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME LOCALIZATION; INTRACELLULAR SPACE; MAMMAL; MITOCHONDRION; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; COMPUTER GRAPHICS; HUMAN; INFORMATION PROCESSING; INTERNET; METABOLISM; SYSTEMS BIOLOGY;

ANIMALS; AUTOMATIC DATA PROCESSING; CHOLESTEROL; COMPUTER GRAPHICS; HUMANS; INTERNET; MAMMALS; METABOLIC NETWORKS AND PATHWAYS; MEVALONIC ACID; MODELS, BIOLOGICAL; SOFTWARE; SQUALENE; SYSTEMS BIOLOGY;

EID: 84884300901     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.03.021     Document Type: Article

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