4β-hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans

British Journal of Clinical Pharmacology

Volumn 71, Issue 2, 2011, Pages 183-189

  Diczfalusy, Ulf ^a   Nylén, Hanna ^a   Elander, Pontus ^a   Bertilsson, Leif ^b  

^a Division of Clinical Chemistry   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

4 hydroxycholesterol; Anti epileptic drugs; Biomarker; CYP3A4; CYP3A5; Ethnicity; Gender; Induction; Inhibition; Rifampicin

Indexed keywords

4BETA HYDROXYCHOLESTEROL; ATAZANAVIR; CARBAMAZEPINE; CHOLESTEROL DERIVATIVE; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; EFAVIRENZ; HYPERICUM PERFORATUM EXTRACT; ITRACONAZOLE; MIDAZOLAM; PHENOBARBITAL; PHENYTOIN; RIFAMPICIN; RITONAVIR; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID; VALPROIC ACID;

ALLELE; ARTICLE; CHOLESTEROL BLOOD LEVEL; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INDUCTION; ENZYME INHIBITION; EPILEPSY; ETHNICITY; FEMALE; GENOTYPE; HALF LIFE TIME; HAPLOTYPE; HUMAN; MALE; METABOLITE; MONITORING; ONYCHOMYCOSIS; PHENOTYPE; PRIORITY JOURNAL; SEX DIFFERENCE;

BIOLOGICAL MARKERS; CYTOCHROME P-450 CYP3A; ETHNIC GROUPS; GENOTYPE; HUMANS; HYDROXYCHOLESTEROLS; PHENOTYPE; SEX CHARACTERISTICS;

EID: 78650982224     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2010.03773.x     Document Type: Article

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