The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

Immunity

Volumn 38, Issue 1, 2013, Pages 106-118

  Blanc, Mathieu ^a   Hsieh, Wei Yuan ^a   Robertson, Kevin A ^a   Kropp, Kai A ^a   Forster, Thorsten ^a   Shui, Guanghou ^b   Lacaze, Paul ^a   Watterson, Steven ^a   Griffiths, Samantha J ^a   Spann, Nathanael J ^c   Meljon, Anna ^d   Talbot, Simon ^a   Krishnan, Kathiresan ^e   Covey, Douglas F ^e   Wenk, Markus R ^b   Craigon, Marie ^a   Ruzsics, Zsolts ^f   Haas, Jürgen ^a   Angulo, Ana ^g   Griffiths, William J ^d   Glass, Christopher K ^c   Wang, Yuqin ^d   Ghazal, Peter ^a   more..

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d SWANSEA UNIVERSITY   (United Kingdom)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF MUNICH   (Germany)

^g INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYCHOLESTEROL; INTERFERON; OXYSTEROL; STAT1 PROTEIN;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; INNATE IMMUNITY; MACROPHAGE; METABOLOMICS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SYNTHESIS; TRANSCRIPTION REGULATION; VIRUS INFECTION;

ANIMALS; ANTIVIRAL AGENTS; BINDING SITES; BONE MARROW CELLS; GENE EXPRESSION REGULATION; HYDROXYCHOLESTEROLS; INTERFERONS; MACROPHAGE ACTIVATION; MACROPHAGES; MEVALONIC ACID; MICE; ORPHAN NUCLEAR RECEPTORS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; STAT1 TRANSCRIPTION FACTOR; STEROID HYDROXYLASES; VIRUS REPLICATION;

EID: 84872794099     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2012.11.004     Document Type: Article

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