Ghrelin-induced food intake and adiposity depend on central mTORC1/S6K1 signaling

Molecular and Cellular Endocrinology

Volumn 381, Issue 1-2, 2013, Pages 280-290

  Stevanovic, Darko ^a,b   Trajkovic, Vladimir ^b   Müller Lühlhoff, Sabrina ^c   Brandt, Elisabeth ^c   Abplanalp, William ^d   Bumke Vogt, Christiane ^a   Liehl, Beate ^a   Wiedmer, Petra ^a   Janjetovic, Kristina ^b   Starcevic, Vesna ^b   Pfeiffer, Andreas F H ^a   Al Hasani, Hadi ^c   Tschöp, Matthias H ^e   Castañeda, Tamara R ^c  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^e INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Body weight; Central nervous system; Food intake; Ghrelin; Insulin; MTORC1 S6K

Indexed keywords

GHRELIN; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RAPAMYCIN; S6 KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FAT MASS; FOOD INTAKE; HYPERPHAGIA; HYPOTHALAMUS; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WEIGHT GAIN;

AGOUTI-RELATED PROTEIN; AGRP; AMP-ACTIVATED PROTEIN KINASE; AMPK; BODY WEIGHT; CALMODULIN-DEPENDENT KINASE KINASE 2; CAMKK2; CENTRAL NERVOUS SYSTEM; DIMETHYL SULFOXIDE; DMSO; FBS; FETAL BOVINE SERUM; FOOD INTAKE; GHRELIN; GHS-R1A; GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1A; ICV; INSULIN; INTRACEREBROVENTRICULAR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MTORC1; MTORC1/S6K; NEUROPEPTIDE Y; NPY; PBS; PHOSPHATE-BUFFERED SALINE; PKA; PROTEIN KINASE A; S6 KINASES; S6K;

ADIPOSE TISSUE, BROWN; ADIPOSITY; ANIMALS; CELL LINE; ENERGY INTAKE; GHRELIN; INSULIN; ION CHANNELS; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; MULTIPROTEIN COMPLEXES; RATS; RATS, WISTAR; RIBOSOMAL PROTEIN S6 KINASES; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84884231872     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.08.009     Document Type: Article

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