메뉴 건너뛰기




Volumn 147, Issue 1-3, 2008, Pages 52-59

Consummatory behavior and metabolic indicators after central ghrelin injections in rats

Author keywords

Adipose tissue; Central nervous system; Consummatory behavior; Ghrelin; ICV; Insulin; Leptin; Rats

Indexed keywords

CHOLESTEROL; CORTICOTROPIN; GHRELIN; GLUCOSE; INSULIN; LEPTIN; TRIACYLGLYCEROL;

EID: 40849083466     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2008.01.003     Document Type: Article
Times cited : (18)

References (67)
  • 1
    • 0036083399 scopus 로고    scopus 로고
    • Ghrelin stimulates insulin secretion from the pancreas of normal and diabetic rats
    • Adeghate E., and Ponery A.S. Ghrelin stimulates insulin secretion from the pancreas of normal and diabetic rats. J Neuroendocrinol 14 (2002) 555-560
    • (2002) J Neuroendocrinol , vol.14 , pp. 555-560
    • Adeghate, E.1    Ponery, A.S.2
  • 2
    • 0142122029 scopus 로고    scopus 로고
    • Ghrelin: central and peripheral effects of a novel peptydil hormone
    • de Ambrogi M., Volpe S., and Tamanini C. Ghrelin: central and peripheral effects of a novel peptydil hormone. Med Sci Monit 9 9 (2003) RA217-RA224
    • (2003) Med Sci Monit , vol.9 , Issue.9
    • de Ambrogi, M.1    Volpe, S.2    Tamanini, C.3
  • 4
    • 0036157858 scopus 로고    scopus 로고
    • Ghrelin and leptin pulse discharge in fed and fasted rats
    • Bagnasco M., Kalra P.S., and Kalra S.P. Ghrelin and leptin pulse discharge in fed and fasted rats. Endocrinology 143 (2002) 726-729
    • (2002) Endocrinology , vol.143 , pp. 726-729
    • Bagnasco, M.1    Kalra, P.S.2    Kalra, S.P.3
  • 5
    • 0036073405 scopus 로고    scopus 로고
    • Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure
    • Banks W.A., Tschop M., Robinson S.M., and Heiman M.L. Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. J Pharmacol Exp Ther 301 (2002) 822-827
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 822-827
    • Banks, W.A.1    Tschop, M.2    Robinson, S.M.3    Heiman, M.L.4
  • 10
    • 15044339140 scopus 로고    scopus 로고
    • Differential effects of methamphetamnine on expression of neuropeptide Y mRNA in hypothalamus and on serum leptin and ghrelin concentrations in ad libitum fed and scheduled fed rats
    • Cowley W.R., Ramoz G., Keefe D.A., Torto R., and Kalra S.P. Differential effects of methamphetamnine on expression of neuropeptide Y mRNA in hypothalamus and on serum leptin and ghrelin concentrations in ad libitum fed and scheduled fed rats. Neuroscience 132 (2005) 167-173
    • (2005) Neuroscience , vol.132 , pp. 167-173
    • Cowley, W.R.1    Ramoz, G.2    Keefe, D.A.3    Torto, R.4    Kalra, S.P.5
  • 11
    • 0035433977 scopus 로고    scopus 로고
    • A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    • Cummings D.E., Purnell J.Q., Frayo R.S., Schmidova K., Wisse B.E., and Weigle D.S. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50 (2001) 1714-1719
    • (2001) Diabetes , vol.50 , pp. 1714-1719
    • Cummings, D.E.1    Purnell, J.Q.2    Frayo, R.S.3    Schmidova, K.4    Wisse, B.E.5    Weigle, D.S.6
  • 13
    • 0038297412 scopus 로고    scopus 로고
    • Ghrelin-leptin tango in body weight regulation
    • Cummings D.E., and Foster K.E. Ghrelin-leptin tango in body weight regulation. Gastroenterology 124 (2003) 1532-1544
    • (2003) Gastroenterology , vol.124 , pp. 1532-1544
    • Cummings, D.E.1    Foster, K.E.2
  • 16
    • 0036181821 scopus 로고    scopus 로고
    • Inhibitory effects of ghrelin on insulin and pancreatic somatostatin secretion
    • Egido E.M., Rodriguez-Gallardo J., Silvestre R.A., and Marco J. Inhibitory effects of ghrelin on insulin and pancreatic somatostatin secretion. Eur J Endocrinol 146 (2002) 241-244
    • (2002) Eur J Endocrinol , vol.146 , pp. 241-244
    • Egido, E.M.1    Rodriguez-Gallardo, J.2    Silvestre, R.A.3    Marco, J.4
  • 17
    • 13444303891 scopus 로고    scopus 로고
    • Hypothalamic hormones a.k.a. hypothalamic releasing factors
    • Guillemin R. Hypothalamic hormones a.k.a. hypothalamic releasing factors. J Endocrinol 184 (2005) 11-28
    • (2005) J Endocrinol , vol.184 , pp. 11-28
    • Guillemin, R.1
  • 19
    • 18344376775 scopus 로고    scopus 로고
    • Stimulation of appetite by ghrelin is regulated by leptin restraint: peripheral and central sites of action
    • Kalra S.P., Ueno N., and Kalra P.S. Stimulation of appetite by ghrelin is regulated by leptin restraint: peripheral and central sites of action. J Nutr 135 (2005) 1331-1335
    • (2005) J Nutr , vol.135 , pp. 1331-1335
    • Kalra, S.P.1    Ueno, N.2    Kalra, P.S.3
  • 20
    • 0034522843 scopus 로고    scopus 로고
    • Central effect of ghrelin and endogenous growth hormone secretagogue, on hypothalamic peptide gene expression
    • Kamegai J., Tamura H., Shimizu T., Ishii S., Sugihara H., and Wakabayashi I. Central effect of ghrelin and endogenous growth hormone secretagogue, on hypothalamic peptide gene expression. Endocrinology 141 (2000) 4797-4800
    • (2000) Endocrinology , vol.141 , pp. 4797-4800
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3    Ishii, S.4    Sugihara, H.5    Wakabayashi, I.6
  • 21
    • 0035513696 scopus 로고    scopus 로고
    • Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and agouti related protein mRNA levels and body weight in rats
    • Kamegai J., Tamura H., Shimizu T., Ishii S., Sugihara H., and Wakabayshi I. Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and agouti related protein mRNA levels and body weight in rats. Diabetes 50 (2001) 2438-2443
    • (2001) Diabetes , vol.50 , pp. 2438-2443
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3    Ishii, S.4    Sugihara, H.5    Wakabayshi, I.6
  • 23
    • 15444366599 scopus 로고    scopus 로고
    • The hypothalamus and obesity
    • King P.J. The hypothalamus and obesity. Curr Drug Targets 6 (2005) 225-240
    • (2005) Curr Drug Targets , vol.6 , pp. 225-240
    • King, P.J.1
  • 24
    • 33845642664 scopus 로고    scopus 로고
    • The role of leptin and ghrelin in the regulation of food intake and body weight in humans
    • Klok M.D., Jakobsdottir S., and Drent M.L. The role of leptin and ghrelin in the regulation of food intake and body weight in humans. Obes Rev 8 (2007) 21-34
    • (2007) Obes Rev , vol.8 , pp. 21-34
    • Klok, M.D.1    Jakobsdottir, S.2    Drent, M.L.3
  • 25
    • 0037382853 scopus 로고    scopus 로고
    • Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin
    • Kohno D., Gao H.Z., Muroya S., Kikuyama S., and Yada T. Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin. Diabetes 52 (2003) 948-956
    • (2003) Diabetes , vol.52 , pp. 948-956
    • Kohno, D.1    Gao, H.Z.2    Muroya, S.3    Kikuyama, S.4    Yada, T.5
  • 26
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth hormone-releasing acylated peptide from stomach
    • Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 27
    • 0035688260 scopus 로고    scopus 로고
    • Purification and distribution of ghrelin: the natural endogenous ligand for the growth hormone secretagogue receptor
    • Kojima M., Hosoda H., and Kangawa K. Purification and distribution of ghrelin: the natural endogenous ligand for the growth hormone secretagogue receptor. Horm Res 56 (2001) 93-97
    • (2001) Horm Res , vol.56 , pp. 93-97
    • Kojima, M.1    Hosoda, H.2    Kangawa, K.3
  • 30
    • 0034678045 scopus 로고    scopus 로고
    • A 6-day intracerebroventricular infusion of the growth hormone-releasing peptide KP-102 stimulates food intake in both non-stressed and intermittently-stressed rats
    • Kuriyama H., Hotta M., Wakabayashi I., and Shibasaki T. A 6-day intracerebroventricular infusion of the growth hormone-releasing peptide KP-102 stimulates food intake in both non-stressed and intermittently-stressed rats. Neurosci Lett 282 (2000) 109-112
    • (2000) Neurosci Lett , vol.282 , pp. 109-112
    • Kuriyama, H.1    Hotta, M.2    Wakabayashi, I.3    Shibasaki, T.4
  • 32
    • 0036141195 scopus 로고    scopus 로고
    • Ghrelin a new gastrointestinal endocine peptide that stimulates insulin secretion: enteric distribution ontogeny, influence of endocrine, and dietary manipulations
    • Lee H.M., Wang G., Englander E.W., Kojima M., and Greeley Jr. J.G. Ghrelin a new gastrointestinal endocine peptide that stimulates insulin secretion: enteric distribution ontogeny, influence of endocrine, and dietary manipulations. Endocrinology 143 (2002) 185-190
    • (2002) Endocrinology , vol.143 , pp. 185-190
    • Lee, H.M.1    Wang, G.2    Englander, E.W.3    Kojima, M.4    Greeley Jr., J.G.5
  • 37
    • 0041428156 scopus 로고    scopus 로고
    • Hypothalamic paraventricular injections of ghrelin: effect on feeding and c-Fos immunoreactivity
    • Olszewski P.K., Grace M.K., Billington C.J., and Levine A.S. Hypothalamic paraventricular injections of ghrelin: effect on feeding and c-Fos immunoreactivity. Peptides 24 (2003) 919-923
    • (2003) Peptides , vol.24 , pp. 919-923
    • Olszewski, P.K.1    Grace, M.K.2    Billington, C.J.3    Levine, A.S.4
  • 38
    • 0037372044 scopus 로고    scopus 로고
    • Dose-dependent inhibition by ghrelin of insulin secretion in the mouse
    • Reimer M.K., Pacini G., and Ahren B. Dose-dependent inhibition by ghrelin of insulin secretion in the mouse. Endocrinology 144 (2003) 916-921
    • (2003) Endocrinology , vol.144 , pp. 916-921
    • Reimer, M.K.1    Pacini, G.2    Ahren, B.3
  • 39
    • 0037320674 scopus 로고    scopus 로고
    • Agouti-related peptide, neuropeptide Y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus
    • Seoane L.M., Lopez M., Tovar S., Casanueva F.F., Senaris R., and Dieguez C. Agouti-related peptide, neuropeptide Y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus. Endocrinology 144 (2003) 544-551
    • (2003) Endocrinology , vol.144 , pp. 544-551
    • Seoane, L.M.1    Lopez, M.2    Tovar, S.3    Casanueva, F.F.4    Senaris, R.5    Dieguez, C.6
  • 40
    • 0016831434 scopus 로고
    • The role of angiotensin in thirst
    • Severs W.B., and Summy-Long J.Y. The role of angiotensin in thirst. Life Sci 17 (1975) 1513-1526
    • (1975) Life Sci , vol.17 , pp. 1513-1526
    • Severs, W.B.1    Summy-Long, J.Y.2
  • 41
    • 0035143816 scopus 로고    scopus 로고
    • Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 pathway
    • Shintani M., Ogawa Y., Ebihara K., Aizawa-Abe M., Miyanaga F., Takaya K., Hayashi T., Inoue G., Hosoda K., Kojima M., Kangawa K., and Nakao K. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 pathway. Diabetes 50 (2001) 227-232
    • (2001) Diabetes , vol.50 , pp. 227-232
    • Shintani, M.1    Ogawa, Y.2    Ebihara, K.3    Aizawa-Abe, M.4    Miyanaga, F.5    Takaya, K.6    Hayashi, T.7    Inoue, G.8    Hosoda, K.9    Kojima, M.10    Kangawa, K.11    Nakao, K.12
  • 42
    • 0028924906 scopus 로고
    • Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression
    • Sipols A.J., Baskin D.G., and Schwartz M.W. Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression. Diabetes 44 (1995) 147-151
    • (1995) Diabetes , vol.44 , pp. 147-151
    • Sipols, A.J.1    Baskin, D.G.2    Schwartz, M.W.3
  • 43
    • 0023773122 scopus 로고
    • Long-term recording of cerebrospinal fluid pressure in freely behaving rats
    • Starcevic V.P., Morrow B.A., Farner L.A., Keil L.C., and Severs W.B. Long-term recording of cerebrospinal fluid pressure in freely behaving rats. Brain Res 462 (1988) 112-117
    • (1988) Brain Res , vol.462 , pp. 112-117
    • Starcevic, V.P.1    Morrow, B.A.2    Farner, L.A.3    Keil, L.C.4    Severs, W.B.5
  • 44
    • 33751316253 scopus 로고    scopus 로고
    • Central effects of ghrelin on serum growth hormone and morphology of pituitary somatotropes in rats
    • Stevanovic D., Milosevic V., Nesic D., Ajdzanovic V., Starcevic V., and Severs W.B. Central effects of ghrelin on serum growth hormone and morphology of pituitary somatotropes in rats. Exp Biol Med 231 (2006) 1610-1615
    • (2006) Exp Biol Med , vol.231 , pp. 1610-1615
    • Stevanovic, D.1    Milosevic, V.2    Nesic, D.3    Ajdzanovic, V.4    Starcevic, V.5    Severs, W.B.6
  • 45
    • 33846540210 scopus 로고    scopus 로고
    • The effect of centrally administered ghrelin on pituitary ACTH cells and circulating ACTH and corticosterone in rats
    • Stevanovic D., Milosevic V., Starcevic V., and Severs W.B. The effect of centrally administered ghrelin on pituitary ACTH cells and circulating ACTH and corticosterone in rats. Life Sci 80 (2007) 867-872
    • (2007) Life Sci , vol.80 , pp. 867-872
    • Stevanovic, D.1    Milosevic, V.2    Starcevic, V.3    Severs, W.B.4
  • 48
    • 0242580169 scopus 로고    scopus 로고
    • Deletion of ghrelin impairs neither growth nor appetite
    • Sun Y., Ahmed S., and Smith R.G. Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol 23 (2006) 7973-7981
    • (2006) Mol Cell Biol , vol.23 , pp. 7973-7981
    • Sun, Y.1    Ahmed, S.2    Smith, R.G.3
  • 49
    • 4644274876 scopus 로고    scopus 로고
    • Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats
    • Tang-Christensen M., Vrang N., Ortmann S., Bidlingmaier M., Horvath T.L., and Tschop M. Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats. Endocrinology 145 (2004) 4645-4652
    • (2004) Endocrinology , vol.145 , pp. 4645-4652
    • Tang-Christensen, M.1    Vrang, N.2    Ortmann, S.3    Bidlingmaier, M.4    Horvath, T.L.5    Tschop, M.6
  • 52
    • 1042275336 scopus 로고    scopus 로고
    • Ghrelin and des-ocatanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of GHS-R 1a
    • Thompson N.M., Gill D.A., Davies R., Loveridge N., Houston P.A., Robinson I.C., and Wells T. Ghrelin and des-ocatanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of GHS-R 1a. Endocrinology 145 (2004) 232-242
    • (2004) Endocrinology , vol.145 , pp. 232-242
    • Thompson, N.M.1    Gill, D.A.2    Davies, R.3    Loveridge, N.4    Houston, P.A.5    Robinson, I.C.6    Wells, T.7
  • 53
    • 0036218881 scopus 로고    scopus 로고
    • Ultradian rhymicity of ghrelin secretion in relation with GH, feeding behavior and sleep-wake patterns in rats
    • Tolle E., Bassant M.H., and Zizzari P. Ultradian rhymicity of ghrelin secretion in relation with GH, feeding behavior and sleep-wake patterns in rats. Endocrinology 143 (2002) 1353-1361
    • (2002) Endocrinology , vol.143 , pp. 1353-1361
    • Tolle, E.1    Bassant, M.H.2    Zizzari, P.3
  • 54
    • 0141872553 scopus 로고    scopus 로고
    • Ghrelin, an endogenous ligand for the growth hormone-secretagogue receptor, is expressed in the human adrenal cortex
    • Tortorella C., Macchi C., Spinazzi R., Malendowicz L.K., Trejter M., and Nussdorfer G.G. Ghrelin, an endogenous ligand for the growth hormone-secretagogue receptor, is expressed in the human adrenal cortex. Int J Mol Med 12 (2003) 213-217
    • (2003) Int J Mol Med , vol.12 , pp. 213-217
    • Tortorella, C.1    Macchi, C.2    Spinazzi, R.3    Malendowicz, L.K.4    Trejter, M.5    Nussdorfer, G.G.6
  • 56
    • 33646401118 scopus 로고    scopus 로고
    • The physiology and potential clinical applications of ghrelin, a novel peptide hormone
    • Tritos N.A., and Kokkotou E.G. The physiology and potential clinical applications of ghrelin, a novel peptide hormone. Mayo Clin Proc 81 (2006) 653-660
    • (2006) Mayo Clin Proc , vol.81 , pp. 653-660
    • Tritos, N.A.1    Kokkotou, E.G.2
  • 57
    • 0034687376 scopus 로고    scopus 로고
    • Grelin induces adiposity in rodents
    • Tschop M., Smiley D.L., and Heiman M.L. Grelin induces adiposity in rodents. Nature 407 (2000) 908-913
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 60
    • 0036150931 scopus 로고    scopus 로고
    • GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for the crucial mediated role of hypothalamic agouti-related protein
    • Tschop M., Statnick M.A., Suter T.M., and Heiman M.L. GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for the crucial mediated role of hypothalamic agouti-related protein. Endocrinology 143 (2002) 558-568
    • (2002) Endocrinology , vol.143 , pp. 558-568
    • Tschop, M.1    Statnick, M.A.2    Suter, T.M.3    Heiman, M.L.4
  • 61
    • 22044441761 scopus 로고    scopus 로고
    • Ghrelin regulates adiposity in white adipose tissue and UCP1 mRNA expression in brown adipose tissue in mice
    • Tsubone T., Masaki T., Katsuragi I., Tanaka K., Kakuma T., and Yoshimatsu H. Ghrelin regulates adiposity in white adipose tissue and UCP1 mRNA expression in brown adipose tissue in mice. Regul Pept 130 (2005) 97-103
    • (2005) Regul Pept , vol.130 , pp. 97-103
    • Tsubone, T.1    Masaki, T.2    Katsuragi, I.3    Tanaka, K.4    Kakuma, T.5    Yoshimatsu, H.6
  • 62
    • 11144262776 scopus 로고    scopus 로고
    • Ghrelin: a gastric peptide that regulates food intake and energy homeostasis
    • Ueno H., Yamaguchi H., Kangawa K., and Nakazato M. Ghrelin: a gastric peptide that regulates food intake and energy homeostasis. Regul Pept 126 (2005) 11-19
    • (2005) Regul Pept , vol.126 , pp. 11-19
    • Ueno, H.1    Yamaguchi, H.2    Kangawa, K.3    Nakazato, M.4
  • 63
    • 0031589705 scopus 로고    scopus 로고
    • Central insulin inhibits hypothalamic galanin and neuropeptide Y gene expression and peptide release in intact rats
    • Wang J., and Leibowitz K.L. Central insulin inhibits hypothalamic galanin and neuropeptide Y gene expression and peptide release in intact rats. Brain Res 777 (1997) 231-236
    • (1997) Brain Res , vol.777 , pp. 231-236
    • Wang, J.1    Leibowitz, K.L.2
  • 66
    • 24844468126 scopus 로고    scopus 로고
    • Continuous subcutaneous administration of ghrelin results in accumulation of adipose tissue, independent of hyperphagia or body weight gain
    • Wren A.M., Small C.J., Thomas E.L., et al. Continuous subcutaneous administration of ghrelin results in accumulation of adipose tissue, independent of hyperphagia or body weight gain. Endocr Abstr oc35 (2004; Spring)
    • (2004) Endocr Abstr , vol.oc35
    • Wren, A.M.1    Small, C.J.2    Thomas, E.L.3
  • 67
    • 0033278997 scopus 로고    scopus 로고
    • Daily changes in hypothalamic gene expression of neuropeptide Y, galanin, pro-opiomelanocortin, and adipocite leptine gene expression and secretion: effects of food restriction
    • Xu B., Kalra P.S., Farmerie W.G., and Kalra. Daily changes in hypothalamic gene expression of neuropeptide Y, galanin, pro-opiomelanocortin, and adipocite leptine gene expression and secretion: effects of food restriction. Endocrinology 140 (1999) 2868-2875
    • (1999) Endocrinology , vol.140 , pp. 2868-2875
    • Xu, B.1    Kalra, P.S.2    Farmerie, W.G.3    Kalra4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.