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Volumn 756, Issue 1-2, 2013, Pages 14-20

Spatiotemporal dynamics of DNA repair proteins following laser microbeam induced DNA damage - When is a DSB not a DSB?

Author keywords

BER; DNA damage; DNA repair; Laser; NHEJ

Indexed keywords

DEOXYRIBONUCLEOPROTEIN; DNA BASE; HISTONE H2AX; XRCC1 PROTEIN;

EID: 84884206125     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2013.05.006     Document Type: Article
Times cited : (26)

References (66)
  • 1
    • 79952075274 scopus 로고    scopus 로고
    • Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment
    • Swenberg J.A., Lu K., Moeller B.C., Gao L., Upton P.B., Nakamura J., Starr T.B. Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment. Toxicol. Sci. 2011, 120:S130-S145.
    • (2011) Toxicol. Sci. , vol.120
    • Swenberg, J.A.1    Lu, K.2    Moeller, B.C.3    Gao, L.4    Upton, P.B.5    Nakamura, J.6    Starr, T.B.7
  • 3
    • 84870587195 scopus 로고    scopus 로고
    • The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage
    • Reynolds P., Anderson J.A., Harper J.V., Hill M.A., Botchway S.W., Parker A.W., O'Neill P. The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage. Nucleic Acids Res. 2012, 40:10821-10831.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 10821-10831
    • Reynolds, P.1    Anderson, J.A.2    Harper, J.V.3    Hill, M.A.4    Botchway, S.W.5    Parker, A.W.6    O'Neill, P.7
  • 6
    • 79956187736 scopus 로고    scopus 로고
    • Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation
    • Asaithamby A., Chen D.J. Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation. Mutat. Res. 2011, 711:87-99.
    • (2011) Mutat. Res. , vol.711 , pp. 87-99
    • Asaithamby, A.1    Chen, D.J.2
  • 7
    • 79961207835 scopus 로고    scopus 로고
    • DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin
    • Jakob B., Splinter J., Conrad S., Voss K.O., Zink D., Durante M., Lobrich M., Taucher-Scholz G. DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin. Nucleic Acids Res. 2011, 39:6489-6499.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 6489-6499
    • Jakob, B.1    Splinter, J.2    Conrad, S.3    Voss, K.O.4    Zink, D.5    Durante, M.6    Lobrich, M.7    Taucher-Scholz, G.8
  • 9
    • 38049007502 scopus 로고    scopus 로고
    • Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells
    • Mortusewicz O., Ame J.C., Schreiber V., Leonhardt H. Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells. Nucleic Acids Res. 2007, 35:7665-7675.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 7665-7675
    • Mortusewicz, O.1    Ame, J.C.2    Schreiber, V.3    Leonhardt, H.4
  • 10
    • 48349135615 scopus 로고    scopus 로고
    • PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility
    • Godon C., Cordelieres F.P., Biard D., Giocanti N., Megnin-Chanet F., Hall J., Favaudon V. PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility. Nucleic Acids Res. 2008, 36:4454-4464.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 4454-4464
    • Godon, C.1    Cordelieres, F.P.2    Biard, D.3    Giocanti, N.4    Megnin-Chanet, F.5    Hall, J.6    Favaudon, V.7
  • 13
    • 0347724033 scopus 로고    scopus 로고
    • Nanoscale spatial induction of ultraviolet photoproducts in cellular DNA by three-photon near-infrared absorption
    • Meldrum R.A., Botchway S.W., Wharton C.W., Hirst G.J. Nanoscale spatial induction of ultraviolet photoproducts in cellular DNA by three-photon near-infrared absorption. EMBO Rep. 2003, 4:1144-1149.
    • (2003) EMBO Rep. , vol.4 , pp. 1144-1149
    • Meldrum, R.A.1    Botchway, S.W.2    Wharton, C.W.3    Hirst, G.J.4
  • 14
    • 0035753555 scopus 로고    scopus 로고
    • Femtosecond near-infrared laser pulse induced strand breaks in mammalian cells
    • Tirlapur U.K., Konig K. Femtosecond near-infrared laser pulse induced strand breaks in mammalian cells. Cell. Mol. Biol. 2001, 47:131-134.
    • (2001) Cell. Mol. Biol. , vol.47 , pp. 131-134
    • Tirlapur, U.K.1    Konig, K.2
  • 15
    • 34547696987 scopus 로고    scopus 로고
    • Near infrared multiphoton-induced generation and detection of hydroxyl radicals in a biochemical system
    • Botchway S.W., Crisostomo A.G., Parker A.W., Bisby R.H. Near infrared multiphoton-induced generation and detection of hydroxyl radicals in a biochemical system. Arch. Biochem. Biophys. 2007, 464:314-321.
    • (2007) Arch. Biochem. Biophys. , vol.464 , pp. 314-321
    • Botchway, S.W.1    Crisostomo, A.G.2    Parker, A.W.3    Bisby, R.H.4
  • 16
    • 33645508174 scopus 로고    scopus 로고
    • Single- and multi-photon excited fluorescence from serotonin complexed with beta-cyclodextrin
    • Bisby R.H., Botchway S.W., Dad S., Parker A.W. Single- and multi-photon excited fluorescence from serotonin complexed with beta-cyclodextrin. Photochem. Photobiol. Sci. 2006, 5:122-125.
    • (2006) Photochem. Photobiol. Sci. , vol.5 , pp. 122-125
    • Bisby, R.H.1    Botchway, S.W.2    Dad, S.3    Parker, A.W.4
  • 17
    • 77951213317 scopus 로고    scopus 로고
    • Specific local induction of DNA strand breaks by infrared multi-photon absorption
    • Trautlein D., Deibler M., Leitenstorfer A., Ferrando-May E. Specific local induction of DNA strand breaks by infrared multi-photon absorption. Nucleic Acids Res. 2010, 38:e14. 10.1093/nar/gkp932.
    • (2010) Nucleic Acids Res. , vol.38
    • Trautlein, D.1    Deibler, M.2    Leitenstorfer, A.3    Ferrando-May, E.4
  • 18
    • 77952099062 scopus 로고    scopus 로고
    • Use of near infrared femtosecond lasers as sub-micron radiation microbeam for cell DNA damage and repair studies
    • Botchway S.W., Reynolds P., Parker A.W., O'Neill P. Use of near infrared femtosecond lasers as sub-micron radiation microbeam for cell DNA damage and repair studies. Mutat. Res. 2010, 704:38-44.
    • (2010) Mutat. Res. , vol.704 , pp. 38-44
    • Botchway, S.W.1    Reynolds, P.2    Parker, A.W.3    O'Neill, P.4
  • 19
    • 84855969346 scopus 로고    scopus 로고
    • Laser-induced radiation microbeam technology and simultaneous real-time fluorescence imaging in live cells
    • Botchway S.W., Reynolds P., Parker A.W., O'Neill P. Laser-induced radiation microbeam technology and simultaneous real-time fluorescence imaging in live cells. Methods Enzymol. 2012, 504:3-28.
    • (2012) Methods Enzymol. , vol.504 , pp. 3-28
    • Botchway, S.W.1    Reynolds, P.2    Parker, A.W.3    O'Neill, P.4
  • 20
    • 0032562595 scopus 로고    scopus 로고
    • In situ visualization of DNA double-strand break repair in human fibroblasts
    • Nelms B.E., Maser R.S., MacKay J.F., Lagally M.G., Petrini J.H. In situ visualization of DNA double-strand break repair in human fibroblasts. Science 1998, 280:590-592.
    • (1998) Science , vol.280 , pp. 590-592
    • Nelms, B.E.1    Maser, R.S.2    MacKay, J.F.3    Lagally, M.G.4    Petrini, J.H.5
  • 22
    • 79959545244 scopus 로고    scopus 로고
    • DNA damage and repair kinetics after microbeam radiation therapy emulation in living cells using monoenergetic synchrotron X-ray microbeams
    • Sprung C.N., Cholewa M., Usami N., Kobayashi K., Crosbie J.C. DNA damage and repair kinetics after microbeam radiation therapy emulation in living cells using monoenergetic synchrotron X-ray microbeams. J. Synchrotron Radiat. 2011, 18:630-636.
    • (2011) J. Synchrotron Radiat. , vol.18 , pp. 630-636
    • Sprung, C.N.1    Cholewa, M.2    Usami, N.3    Kobayashi, K.4    Crosbie, J.C.5
  • 23
    • 0031426132 scopus 로고    scopus 로고
    • Wavelength dependence of oxidative DNA damage induced by UV and visible light
    • Kielbassa C., Roza L., Epe B. Wavelength dependence of oxidative DNA damage induced by UV and visible light. Carcinogenesis 1997, 18:811-816.
    • (1997) Carcinogenesis , vol.18 , pp. 811-816
    • Kielbassa, C.1    Roza, L.2    Epe, B.3
  • 24
    • 0032875279 scopus 로고    scopus 로고
    • Oxidative DNA damage and mutations induced by a polar photosensitizer, Ro19-8022
    • Will O., Gocke E., Eckert I., Schulz I., Pflaum M., Mahler H.C., Epe B. Oxidative DNA damage and mutations induced by a polar photosensitizer, Ro19-8022. Mutat. Res. 1999, 435:89-101.
    • (1999) Mutat. Res. , vol.435 , pp. 89-101
    • Will, O.1    Gocke, E.2    Eckert, I.3    Schulz, I.4    Pflaum, M.5    Mahler, H.C.6    Epe, B.7
  • 25
    • 0026794780 scopus 로고
    • Photosensitized formation of 8-hydroxydeoxyguanosine in cellular DNA by riboflavin
    • Yamamoto F., Nishimura S., Kasai H. Photosensitized formation of 8-hydroxydeoxyguanosine in cellular DNA by riboflavin. Biochem. Biophys. Res. Commun. 1992, 187:809-813.
    • (1992) Biochem. Biophys. Res. Commun. , vol.187 , pp. 809-813
    • Yamamoto, F.1    Nishimura, S.2    Kasai, H.3
  • 26
    • 25144514003 scopus 로고    scopus 로고
    • Imaging of protein movement induced by chromosomal breakage: tiny 'local' lesions pose great 'global' challenges
    • Lukas C., Bartek J., Lukas J. Imaging of protein movement induced by chromosomal breakage: tiny 'local' lesions pose great 'global' challenges. Chromosoma 2005, 114:146-154.
    • (2005) Chromosoma , vol.114 , pp. 146-154
    • Lukas, C.1    Bartek, J.2    Lukas, J.3
  • 27
    • 51649086880 scopus 로고    scopus 로고
    • Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells
    • Cadet J., Douki T., Ravanat J.L. Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells. Acc. Chem. Res. 2008, 41:1075-1083.
    • (2008) Acc. Chem. Res. , vol.41 , pp. 1075-1083
    • Cadet, J.1    Douki, T.2    Ravanat, J.L.3
  • 28
    • 0024195429 scopus 로고
    • DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability
    • Ward J.F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. Prog. Nucleic Acid Res. Mol. Biol. 1988, 35:95-125.
    • (1988) Prog. Nucleic Acid Res. Mol. Biol. , vol.35 , pp. 95-125
    • Ward, J.F.1
  • 29
    • 33645144591 scopus 로고    scopus 로고
    • Induction and quantification of gamma-H2AX foci following low and high LET-irradiation
    • Leatherbarrow E.L., Harper J.V., Cucinotta F.A., O'Neill P. Induction and quantification of gamma-H2AX foci following low and high LET-irradiation. Int. J. Radiat. Biol. 2006, 82:111-118.
    • (2006) Int. J. Radiat. Biol. , vol.82 , pp. 111-118
    • Leatherbarrow, E.L.1    Harper, J.V.2    Cucinotta, F.A.3    O'Neill, P.4
  • 31
    • 0027494358 scopus 로고
    • Induction and rejoining of DNA double-strand breaks in V79-4 mammalian cells following gamma- and alpha-irradiation
    • Jenner T.J., deLara C.M., O'Neill P., Stevens D.L. Induction and rejoining of DNA double-strand breaks in V79-4 mammalian cells following gamma- and alpha-irradiation. Int. J. Radiat. Biol. 1993, 64:265-273.
    • (1993) Int. J. Radiat. Biol. , vol.64 , pp. 265-273
    • Jenner, T.J.1    deLara, C.M.2    O'Neill, P.3    Stevens, D.L.4
  • 32
    • 0027976408 scopus 로고
    • Initial events in the cellular effects of ionizing radiations: clustered damage in DNA
    • Goodhead D.T. Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. Int. J. Radiat. Biol. 1994, 65:7-17.
    • (1994) Int. J. Radiat. Biol. , vol.65 , pp. 7-17
    • Goodhead, D.T.1
  • 33
    • 23044477801 scopus 로고    scopus 로고
    • Characterization of complex apurinic/apyrimidinic-site clustering associated with an authentic site-specific radiation-induced DNA double-strand break
    • Datta K., Neumann R.D., Winters T.A. Characterization of complex apurinic/apyrimidinic-site clustering associated with an authentic site-specific radiation-induced DNA double-strand break. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:10569-10574.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 10569-10574
    • Datta, K.1    Neumann, R.D.2    Winters, T.A.3
  • 34
    • 77952089468 scopus 로고    scopus 로고
    • Satiotempral analysis of DNA repair using charged particle radiation
    • Tobias F., Durante M., Taucher-Scholz G., Jakob B. Satiotempral analysis of DNA repair using charged particle radiation. Mutat. Res. 2011, 704:54-60.
    • (2011) Mutat. Res. , vol.704 , pp. 54-60
    • Tobias, F.1    Durante, M.2    Taucher-Scholz, G.3    Jakob, B.4
  • 35
  • 36
  • 39
    • 55649098355 scopus 로고    scopus 로고
    • Induction of persistent double strand breaks following multiphoton irradiation of cycling and G1-arrested mammalian cells-replication-induced double strand breaks
    • Harper J.V., Reynolds P., Leatherbarrow E.L., Botchway S.W., Parker A.W., O'Neill P. Induction of persistent double strand breaks following multiphoton irradiation of cycling and G1-arrested mammalian cells-replication-induced double strand breaks. Photochem. Photobiol. 2008, 84:1506-1514.
    • (2008) Photochem. Photobiol. , vol.84 , pp. 1506-1514
    • Harper, J.V.1    Reynolds, P.2    Leatherbarrow, E.L.3    Botchway, S.W.4    Parker, A.W.5    O'Neill, P.6
  • 41
    • 0030806073 scopus 로고    scopus 로고
    • Induction and rejoining of DNA double-strand breaks in Chinese hamster V79-4 cells irradiated with characteristic aluminum K and copper L ultrasoft X rays
    • Botchway S.W., Stevens D.L., Hill M.A., Jenner T.J., O'Neill P. Induction and rejoining of DNA double-strand breaks in Chinese hamster V79-4 cells irradiated with characteristic aluminum K and copper L ultrasoft X rays. Radiat. Res. 1997, 148:317-324.
    • (1997) Radiat. Res. , vol.148 , pp. 317-324
    • Botchway, S.W.1    Stevens, D.L.2    Hill, M.A.3    Jenner, T.J.4    O'Neill, P.5
  • 42
    • 0035242368 scopus 로고    scopus 로고
    • Femtosecond near-infrared laser pulses elicit generation of reactive oxygen species in mammalian cells leading to apoptosis-like death
    • Tirlapur U.K., Konig K., Peuckert C., Krieg R., Halbhuber K.J. Femtosecond near-infrared laser pulses elicit generation of reactive oxygen species in mammalian cells leading to apoptosis-like death. Exp. Cell Res. 2001, 263:88-97.
    • (2001) Exp. Cell Res. , vol.263 , pp. 88-97
    • Tirlapur, U.K.1    Konig, K.2    Peuckert, C.3    Krieg, R.4    Halbhuber, K.J.5
  • 45
    • 0027966126 scopus 로고
    • Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks
    • Rathmell W.K., Chu G. Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:7623-7627.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 7623-7627
    • Rathmell, W.K.1    Chu, G.2
  • 46
    • 0030009738 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit
    • Chan D.W., Lees-Miller S.P. The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit. J. Biol. Chem. 1996, 271:8936-8941.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8936-8941
    • Chan, D.W.1    Lees-Miller, S.P.2
  • 47
    • 0029928176 scopus 로고    scopus 로고
    • Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants
    • Errami A., Smider V., Rathmell W.K., He D.M., Hendrickson E.A., Zdzienicka M.Z., Chu G. Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants. Mol. Cell. Biol. 1996, 16:1519-1526.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1519-1526
    • Errami, A.1    Smider, V.2    Rathmell, W.K.3    He, D.M.4    Hendrickson, E.A.5    Zdzienicka, M.Z.6    Chu, G.7
  • 48
    • 80052619178 scopus 로고    scopus 로고
    • Accumulation of Ku70 at DNA double-strand breaks in living epithelial cells
    • Koike M., Yutoku Y., Koike A. Accumulation of Ku70 at DNA double-strand breaks in living epithelial cells. Exp. Cell Res. 2011, 317:2429-2437.
    • (2011) Exp. Cell Res. , vol.317 , pp. 2429-2437
    • Koike, M.1    Yutoku, Y.2    Koike, A.3
  • 49
    • 84862777619 scopus 로고    scopus 로고
    • The E3 ligase RNF8 regulates Ku80 removal and NHEJ repair
    • Feng L., Chen J. The E3 ligase RNF8 regulates Ku80 removal and NHEJ repair. Nat. Struct. Mol. Biol. 2012, 19:201-206.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 201-206
    • Feng, L.1    Chen, J.2
  • 50
    • 77955434227 scopus 로고    scopus 로고
    • Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks
    • Davis A.J., So S., Chen D.J. Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks. Cell Cycle 2010, 9:2529-2536.
    • (2010) Cell Cycle , vol.9 , pp. 2529-2536
    • Davis, A.J.1    So, S.2    Chen, D.J.3
  • 53
  • 54
    • 77955145610 scopus 로고    scopus 로고
    • Participation of DNA-PKcs in DSB repair after exposure to high- and low-LET radiation
    • Anderson J.A., Harper J.V., Cucinotta F.A., O'Neill P. Participation of DNA-PKcs in DSB repair after exposure to high- and low-LET radiation. Radiat. Res. 2010, 174:195-205.
    • (2010) Radiat. Res. , vol.174 , pp. 195-205
    • Anderson, J.A.1    Harper, J.V.2    Cucinotta, F.A.3    O'Neill, P.4
  • 55
    • 2542637919 scopus 로고    scopus 로고
    • Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation
    • Gulston M., de Lara C., Jenner T., Davis E., O'Neill P. Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation. Nucleic Acids Res. 2004, 32:1602-1609.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1602-1609
    • Gulston, M.1    de Lara, C.2    Jenner, T.3    Davis, E.4    O'Neill, P.5
  • 56
    • 0035102055 scopus 로고    scopus 로고
    • Dependence of the yield of DNA double-strand breaks in Chinese hamster V79-4 cells on the photon energy of ultrasoft X rays
    • de Lara C.M., Hill M.A., Jenner T.J., Papworth D., O'Neill P. Dependence of the yield of DNA double-strand breaks in Chinese hamster V79-4 cells on the photon energy of ultrasoft X rays. Radiat. Res. 2001, 155:440-448.
    • (2001) Radiat. Res. , vol.155 , pp. 440-448
    • de Lara, C.M.1    Hill, M.A.2    Jenner, T.J.3    Papworth, D.4    O'Neill, P.5
  • 58
    • 0033291595 scopus 로고    scopus 로고
    • RBE-LET relationships in mutagenesis by ionizing radiation
    • Nikjoo H., Munson R.J., Bridges B.A. RBE-LET relationships in mutagenesis by ionizing radiation. J. Radiat. Res. 1999, 40:85-105.
    • (1999) J. Radiat. Res. , vol.40 , pp. 85-105
    • Nikjoo, H.1    Munson, R.J.2    Bridges, B.A.3
  • 59
    • 0022991416 scopus 로고
    • DNA repair kinetics after exposure to X-irradiation and to internal beta-rays in CHO cells
    • Dikomey E., Franzke J. DNA repair kinetics after exposure to X-irradiation and to internal beta-rays in CHO cells. Radiat. Environ. Biophys. 1986, 25:189-194.
    • (1986) Radiat. Environ. Biophys. , vol.25 , pp. 189-194
    • Dikomey, E.1    Franzke, J.2
  • 60
    • 77950360354 scopus 로고    scopus 로고
    • Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage
    • Eccles L.J., Lomax M.E., O'Neill P. Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage. Nucleic Acids Res. 2010, 38:1123-1134.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 1123-1134
    • Eccles, L.J.1    Lomax, M.E.2    O'Neill, P.3
  • 61
    • 46649102827 scopus 로고    scopus 로고
    • Interplay of two major repair pathways in the processing of complex double-strand DNA breaks
    • Dobbs T.A., Palmer P., Maniou Z., Lomax M.E., O'Neill P. Interplay of two major repair pathways in the processing of complex double-strand DNA breaks. DNA Repair 2008, 7:1372-1383.
    • (2008) DNA Repair , vol.7 , pp. 1372-1383
    • Dobbs, T.A.1    Palmer, P.2    Maniou, Z.3    Lomax, M.E.4    O'Neill, P.5
  • 62
    • 33750736349 scopus 로고    scopus 로고
    • Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break
    • Datta K., Jaruga P., Dizdaroglu M., Neumann R.D., Winters T.A. Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break. Radiat. Res. 2006, 166:767-781.
    • (2006) Radiat. Res. , vol.166 , pp. 767-781
    • Datta, K.1    Jaruga, P.2    Dizdaroglu, M.3    Neumann, R.D.4    Winters, T.A.5
  • 63
    • 79956225907 scopus 로고    scopus 로고
    • Clustered DNA lesion repair in eukaryotes: relevance to mutagenesis and cell survival
    • Sage E., Harrison L. Clustered DNA lesion repair in eukaryotes: relevance to mutagenesis and cell survival. Mutat. Res. 2011, 711:123-133.
    • (2011) Mutat. Res. , vol.711 , pp. 123-133
    • Sage, E.1    Harrison, L.2
  • 64
    • 79957686784 scopus 로고    scopus 로고
    • Unrepaired clustered DNA lesions induce chromosome breakage in human cells
    • Asaithamby A., Hu B., Chen D.J. Unrepaired clustered DNA lesions induce chromosome breakage in human cells. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:8293-8298.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 8293-8298
    • Asaithamby, A.1    Hu, B.2    Chen, D.J.3
  • 65
    • 79956197636 scopus 로고    scopus 로고
    • Delayed repair of radiation induced clustered DNA damage: friend or foe?
    • Eccles L.J., O'Neill P., Lomax M.E. Delayed repair of radiation induced clustered DNA damage: friend or foe?. Mutat. Res. 2011, 711:134-141.
    • (2011) Mutat. Res. , vol.711 , pp. 134-141
    • Eccles, L.J.1    O'Neill, P.2    Lomax, M.E.3
  • 66
    • 79952573454 scopus 로고    scopus 로고
    • Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF
    • Yano K.I., Morotomi-Yano K., Lee K.J., Chen D.J. Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF. FEBS Lett. 2011, 585:841-846.
    • (2011) FEBS Lett. , vol.585 , pp. 841-846
    • Yano, K.I.1    Morotomi-Yano, K.2    Lee, K.J.3    Chen, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.