-
1
-
-
0035256772
-
Gliomagenesis: Genetic alterations and mouse models
-
Holland EC. Gliomagenesis: genetic alterations and mouse models. Nat Rev Genet 2001; 2: 120-129.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 120-129
-
-
Holland, E.C.1
-
2
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007; 114: 97-109.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
-
3
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005; 352: 987-996.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
4
-
-
33846120980
-
Therapeutic advances for glioblastoma multiforme: Current status and future prospects
-
Robins HI, Chang S, Butowski N, Mehta M. Therapeutic advances for glioblastoma multiforme: current status and future prospects. Curr Oncol Reports 2007; 9: 66-70.
-
(2007)
Curr Oncol Reports
, vol.9
, pp. 66-70
-
-
Robins, H.I.1
Chang, S.2
Butowski, N.3
Mehta, M.4
-
5
-
-
0034987702
-
Malignant glioma: Genetics and biology of a grave matter
-
Maher EA, Furnari FB, Bachoo RM, et al. Malignant glioma: genetics and biology of a grave matter. Genes Dev 2001; 15: 1311-1333.
-
(2001)
Genes Dev
, vol.15
, pp. 1311-1333
-
-
Maher, E.A.1
Furnari, F.B.2
Bachoo, R.M.3
-
6
-
-
35949002429
-
Malignant astrocytic glioma: Genetics, biology, and paths to treatment
-
Furnari FB, Fenton T, Bachoo RM, et al. Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev 2007; 21: 2683-2710.
-
(2007)
Genes Dev
, vol.21
, pp. 2683-2710
-
-
Furnari, F.B.1
Fenton, T.2
Bachoo, R.M.3
-
7
-
-
48249125791
-
Malignant gliomas in adults
-
Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med 2008; 359: 492-507.
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
8
-
-
19044397160
-
Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
-
Bachoo RM, Maher EA, Ligon KL, et al. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 2002; 1:269-277.
-
(2002)
Cancer Cell
, vol.1
, pp. 269-277
-
-
Bachoo, R.M.1
Maher, E.A.2
Ligon, K.L.3
-
9
-
-
0036791177
-
Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt
-
Uhrbom L, Dai C, Celestino JC, et al. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Res 2002; 62: 5551-5558.
-
(2002)
Cancer Res
, vol.62
, pp. 5551-5558
-
-
Uhrbom, L.1
Dai, C.2
Celestino, J.C.3
-
10
-
-
33645732219
-
Molecular pathology of malignant gliomas
-
Louis DN: Molecular pathology of malignant gliomas. Annu Rev Pathol 2006; 1: 97-117.
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 97-117
-
-
Louis, D.N.1
-
11
-
-
0346059618
-
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity
-
Bajenaru ML, Hernandez MR, Perry A, et al. Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. Cancer Res 2003; 63: 8573-8577.
-
(2003)
Cancer Res
, vol.63
, pp. 8573-8577
-
-
Bajenaru, M.L.1
Hernandez, M.R.2
Perry, A.3
-
12
-
-
0037302119
-
Signaling pathways regulating gliomagenesis
-
Konopka G, Bonni A. Signaling pathways regulating gliomagenesis. Curr Mol Med 2003; 3: 73-84.
-
(2003)
Curr Mol Med
, vol.3
, pp. 73-84
-
-
Konopka, G.1
Bonni, A.2
-
13
-
-
84859183715
-
Malignant glioma: Lessons from genomics, mouse models, and stem cells
-
Chen J, McKay RM, Parada LF. Malignant glioma: lessons from genomics, mouse models, and stem cells. Cell 2012; 149: 36-47.
-
(2012)
Cell
, vol.149
, pp. 36-47
-
-
Chen, J.1
McKay, R.M.2
Parada, L.F.3
-
14
-
-
0026548240
-
Structural alterations of the epidermal growth factor receptor gene in human gliomas
-
Wong AJ, Ruppert JM, Bigner SH, et al. Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proc Natl Acad Sci USA 1992; 89: 2965-2969.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2965-2969
-
-
Wong, A.J.1
Ruppert, J.M.2
Bigner, S.H.3
-
15
-
-
0035142469
-
Aberrant receptor signaling in human malignant gliomas: Mechanisms and therapeutic implications
-
Nagane M, Lin H, Cavenee WK, Huang HJ. Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications. Cancer Lett 2001; 162: S17-S21.
-
(2001)
Cancer Lett
, vol.162
-
-
Nagane, M.1
Lin, H.2
Cavenee, W.K.3
Huang, H.J.4
-
16
-
-
84858156041
-
Landscape of EGFR signaling network in human cancers: Biology and therapeutic response in relation to receptor subcellular locations
-
Han W, Lo HW. Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations. Cancer Lett 2012; 318: 124-134.
-
(2012)
Cancer Lett
, vol.318
, pp. 124-134
-
-
Han, W.1
Lo, H.W.2
-
17
-
-
33845370278
-
Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: Correlation with EGFR status, tumor grade, and survival
-
Mizoguchi M, Betensky RA, Batchelor TT, et al. Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: correlation with EGFR status, tumor grade, and survival. J Neuropath Exp Neur 2006; 65: 1181-1188.
-
(2006)
J Neuropath Exp Neur
, vol.65
, pp. 1181-1188
-
-
Mizoguchi, M.1
Betensky, R.A.2
Batchelor, T.T.3
-
18
-
-
3543025709
-
Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II
-
Boerner JL, Demory ML, Silva C, Parsons SJ. Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II. Mol Cell Biol 2004; 24: 7059-7071.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7059-7071
-
-
Boerner, J.L.1
Demory, M.L.2
Silva, C.3
Parsons, S.J.4
-
19
-
-
73649140612
-
Epidermal growth factor receptor translocation to the mitochondria: Regulation and effect
-
Demory ML, Boerner JL, Davidson R, et al. Epidermal growth factor receptor translocation to the mitochondria: regulation and effect. J Biol Chem 2009; 284: 36592-36604.
-
(2009)
J Biol Chem
, vol.284
, pp. 36592-36604
-
-
Demory, M.L.1
Boerner, J.L.2
Davidson, R.3
-
20
-
-
48249138450
-
Mitochondrially localized EGFR is subjected to autophagic regulation and implicated in cell survival
-
Yue X, Song W, Zhang W, et al. Mitochondrially localized EGFR is subjected to autophagic regulation and implicated in cell survival. Autophagy 2008; 4: 641-649.
-
(2008)
Autophagy
, vol.4
, pp. 641-649
-
-
Yue, X.1
Song, W.2
Zhang, W.3
-
21
-
-
0034855942
-
Nuclear localization of EGF receptor and its potential new role as a transcription factor
-
Lin SY, Makino K, Xia W, et al. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat Cell Biol 2001; 3: 802-808.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 802-808
-
-
Lin, S.Y.1
Makino, K.2
Xia, W.3
-
22
-
-
20444423286
-
Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway
-
Lo HW, Hsu SC, Ali-Seyed M, Bartholomeusz G, Shih JY, Hung MC et al.: Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway. Cancer Cell 2005; 7: 575-589.
-
(2005)
Cancer Cell
, vol.7
, pp. 575-589
-
-
Lo, H.W.1
Hsu, S.C.2
Ali-Seyed, M.3
Bartholomeusz, G.4
Shih, J.Y.5
Hung, M.C.6
-
23
-
-
39449093328
-
Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway
-
de la Iglesia N, Konopka G, Puram SV, et al. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev 2008; 22: 449-462.
-
(2008)
Genes Dev
, vol.22
, pp. 449-462
-
-
de la Iglesia, N.1
Konopka, G.2
Puram, S.V.3
-
24
-
-
77954759289
-
Nuclear trafficking of the epidermal growth factor receptor family membrane proteins
-
Wang YN, Yamaguchi H, Hsu JM, Hung MC. Nuclear trafficking of the epidermal growth factor receptor family membrane proteins. Oncogene 2010; 29: 3997-4006.
-
(2010)
Oncogene
, vol.29
, pp. 3997-4006
-
-
Wang, Y.N.1
Yamaguchi, H.2
Hsu, J.M.3
Hung, M.C.4
-
25
-
-
79151472321
-
Nuclear mode of the EGFR signaling network: Biology, prognostic value, and therapeutic implications
-
Lo HW. Nuclear mode of the EGFR signaling network: biology, prognostic value, and therapeutic implications. Discovery Med 2010; 10: 44-51.
-
(2010)
Discovery Med
, vol.10
, pp. 44-51
-
-
Lo, H.W.1
-
28
-
-
0032525155
-
Multiple routes to astrocytic differentiation in the CNS
-
Rajan P, McKay RD. Multiple routes to astrocytic differentiation in the CNS. J Neurosci 1998; 18: 3620-3629.
-
(1998)
J Neurosci
, vol.18
, pp. 3620-3629
-
-
Rajan, P.1
McKay, R.D.2
-
29
-
-
0030708523
-
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway
-
Bonni A, Sun Y, Nadal-Vicens M, et al. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science 1997; 278: 477-483.
-
(1997)
Science
, vol.278
, pp. 477-483
-
-
Bonni, A.1
Sun, Y.2
Nadal-Vicens, M.3
-
30
-
-
33746397211
-
Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex
-
Yoshimatsu T, Kawaguchi D, Oishi K, et al. Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development 2006; 133:2553-2563.
-
(2006)
Development
, vol.133
, pp. 2553-2563
-
-
Yoshimatsu, T.1
Kawaguchi, D.2
Oishi, K.3
-
31
-
-
44949176222
-
Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness
-
de la Iglesia N, Konopka G, Lim KL, et al. Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness. J Neurosci 2008; 28: 5870-5878.
-
(2008)
J Neurosci
, vol.28
, pp. 5870-5878
-
-
de la Iglesia, N.1
Konopka, G.2
Lim, K.L.3
-
32
-
-
84861921204
-
STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation
-
Puram SV, Yeung CM, Jahani-Asl A, et al. STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation. J Neurosci 2012; 32: 7806-7818.
-
(2012)
J Neurosci
, vol.32
, pp. 7806-7818
-
-
Puram, S.V.1
Yeung, C.M.2
Jahani-Asl, A.3
-
33
-
-
1542349094
-
The STAT3 DNA-binding domain mediates interaction with NF-kappaB p65 and inducible nitric oxide synthase transrepression in mesangial cells
-
Yu Z, Kone BC. The STAT3 DNA-binding domain mediates interaction with NF-kappaB p65 and inducible nitric oxide synthase transrepression in mesangial cells. J Am Soc Nephrol (JASN) 2004; 15: 585-591.
-
(2004)
J Am Soc Nephrol (JASN)
, vol.15
, pp. 585-591
-
-
Yu, Z.1
Kone, B.C.2
-
34
-
-
0036797750
-
Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB
-
Yu Z, Zhang W, Kone BC. Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB. Biochem J 2002; 367: 97-105.
-
(2002)
Biochem J
, vol.367
, pp. 97-105
-
-
Yu, Z.1
Zhang, W.2
Kone, B.C.3
-
35
-
-
3042748279
-
Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
-
Konnikova L, Kotecki M, Kruger MM, Cochran BH. Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer 2003; 3: 23.
-
(2003)
BMC Cancer
, vol.3
, pp. 23
-
-
Konnikova, L.1
Kotecki, M.2
Kruger, M.M.3
Cochran, B.H.4
-
36
-
-
0037028249
-
Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells
-
Rahaman SO, Harbor PC, Chernova O, et al. Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells. Oncogene 2002; 21: 8404-8413.
-
(2002)
Oncogene
, vol.21
, pp. 8404-8413
-
-
Rahaman, S.O.1
Harbor, P.C.2
Chernova, O.3
-
37
-
-
60349107511
-
Stat3 activation is required for the growth of U87 cell-derived tumours in mice
-
Dasgupta A, Raychaudhuri B, Haqqi T, et al. Stat3 activation is required for the growth of U87 cell-derived tumours in mice. Eur J Cancer 2009; 45: 677-684.
-
(2009)
Eur J Cancer
, vol.45
, pp. 677-684
-
-
Dasgupta, A.1
Raychaudhuri, B.2
Haqqi, T.3
-
38
-
-
75149195336
-
The transcriptional network for mesenchymal transformation of brain tumours
-
Carro MS, Lim WK, Alvarez MJ, et al. The transcriptional network for mesenchymal transformation of brain tumours. Nature 2010; 463: 318-325.
-
(2010)
Nature
, vol.463
, pp. 318-325
-
-
Carro, M.S.1
Lim, W.K.2
Alvarez, M.J.3
-
39
-
-
46949092766
-
Blockage of the STAT3 signaling pathway with a decoy oligonucleotide suppresses growth of human malignant glioma cells
-
Gu J, Li G, Sun T, et al. Blockage of the STAT3 signaling pathway with a decoy oligonucleotide suppresses growth of human malignant glioma cells. J Neuro-Oncol 2008, 89: 9-17.
-
(2008)
J Neuro-Oncol
, vol.89
, pp. 9-17
-
-
Gu, J.1
Li, G.2
Sun, T.3
-
40
-
-
79959969874
-
Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2
-
Eyler CE, Wu Q, Yan K, et al. Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell 2011;146: 53-66.
-
(2011)
Cell
, vol.146
, pp. 53-66
-
-
Eyler, C.E.1
Wu, Q.2
Yan, K.3
-
41
-
-
0025883342
-
Nitric oxide: Physiology, pathophysiology, and pharmacology
-
Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109-142.
-
(1991)
Pharmacol Rev
, vol.43
, pp. 109-142
-
-
Moncada, S.1
Palmer, R.M.2
Higgs, E.A.3
-
42
-
-
0036196417
-
NO as a signalling molecule in the nervous system
-
Esplugues JV. NO as a signalling molecule in the nervous system. Brit J Pharmacol 2002; 135: 1079-1095.
-
(2002)
Brit J Pharmacol
, vol.135
, pp. 1079-1095
-
-
Esplugues, J.V.1
-
43
-
-
70349109668
-
Cerebral blood flow regulation by nitric oxide in neurological disorders
-
Toda N, Ayajiki K, Okamura T. Cerebral blood flow regulation by nitric oxide in neurological disorders. Can. J Physiol Pharm 2009; 87: 581-594.
-
(2009)
Can J Physiol Pharm
, vol.87
, pp. 581-594
-
-
Toda, N.1
Ayajiki, K.2
Okamura, T.3
-
45
-
-
9244232804
-
Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53
-
Forrester K, Ambs S, Lupold SE, et al. Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. Proc Natl Acad Sci USA 1996; 93: 2442-2447.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2442-2447
-
-
Forrester, K.1
Ambs, S.2
Lupold, S.E.3
-
46
-
-
0346690271
-
Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells
-
Cobbs CS, Whisenhunt TR, Wesemann DR, et al. Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells. Cancer Res 2003; 63: 8670-8673.
-
(2003)
Cancer Res
, vol.63
, pp. 8670-8673
-
-
Cobbs, C.S.1
Whisenhunt, T.R.2
Wesemann, D.R.3
-
47
-
-
79959582633
-
Nitric oxide: Role in tumour biology and iNOS/NO-based anticancer therapies
-
Singh S, Gupta AK. Nitric oxide: role in tumour biology and iNOS/NO-based anticancer therapies. Cancer Chemother Pharmacol 2011; 67: 1211-1224.
-
(2011)
Cancer Chemother Pharmacol
, vol.67
, pp. 1211-1224
-
-
Singh, S.1
Gupta, A.K.2
-
48
-
-
0035853035
-
Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): Potential role of cyclin D1
-
Pervin S, Singh R, Chaudhuri G. Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): potential role of cyclin D1. Proc Natl Acad Sci USA 2001; 98: 3583-3588.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3583-3588
-
-
Pervin, S.1
Singh, R.2
Chaudhuri, G.3
-
49
-
-
0035874941
-
Potentiation of nitric oxide-induced apoptosis of MDA-MB-468 cells by farnesyltransferase inhibitor: Implications in breast cancer
-
Pervin S, Singh R, Gau CL, et al. Potentiation of nitric oxide-induced apoptosis of MDA-MB-468 cells by farnesyltransferase inhibitor: implications in breast cancer. Cancer Res 2001; 61: 4701-4706.
-
(2001)
Cancer Res
, vol.61
, pp. 4701-4706
-
-
Pervin, S.1
Singh, R.2
Gau, C.L.3
-
50
-
-
33846416533
-
Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: Involvement of mammalian target of rapamycin/eIF4E pathway
-
Pervin S, Singh R, Hernandez E, Wu G, Chaudhuri G. Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway. Cancer Res 2007; 67: 289-299.
-
(2007)
Cancer Res
, vol.67
, pp. 289-299
-
-
Pervin, S.1
Singh, R.2
Hernandez, E.3
Wu, G.4
Chaudhuri, G.5
-
51
-
-
2942665472
-
Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide
-
Thomas DD, Espey MG, Ridnour LA, et al. Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide. Proc Natl Acad Sci USA 2004; 101: 8894-8899.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8894-8899
-
-
Thomas, D.D.1
Espey, M.G.2
Ridnour, L.A.3
-
52
-
-
36749026266
-
Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways
-
Ridnour LA, Windhausen AN, Isenberg JS, et al. Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways. Proc Natl Acad Sci USA 2007; 104: 16898-16903.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 16898-16903
-
-
Ridnour, L.A.1
Windhausen, A.N.2
Isenberg, J.S.3
-
54
-
-
2542455472
-
iNOS-mediated nitric oxide production and its regulation
-
Aktan F. iNOS-mediated nitric oxide production and its regulation. Life Sci 2004; 75: 639-653.
-
(2004)
Life Sci
, vol.75
, pp. 639-653
-
-
Aktan, F.1
-
55
-
-
0031196115
-
Nitric oxide and reproduction
-
Rosselli M. Nitric oxide and reproduction. Mol Hum Reprod 1997; 3: 639-641.
-
(1997)
Mol Hum Reprod
, vol.3
, pp. 639-641
-
-
Rosselli, M.1
-
56
-
-
84859487532
-
Nitric oxide synthases: Regulation and function
-
Forstermann U, Sessa WC. Nitric oxide synthases: regulation and function. Eur Heart J 2012; 33: 829-837.
-
(2012)
Eur Heart J
, vol.33
, pp. 829-837
-
-
Forstermann, U.1
Sessa, W.C.2
-
58
-
-
0028035106
-
The high-output nitric oxide pathway: Role and regulation
-
Xie Q, Nathan C. The high-output nitric oxide pathway: role and regulation. J Leukoc Biol 1994; 56: 576-582.
-
(1994)
J Leukoc Biol
, vol.56
, pp. 576-582
-
-
Xie, Q.1
Nathan, C.2
-
59
-
-
77954624383
-
Regulation of the expression of inducible nitric oxide synthase
-
Pautz A, Art J, Hahn S, Nowag S, Voss C, Kleinert H. Regulation of the expression of inducible nitric oxide synthase. Nitric Oxide 2010; 23: 75-93.
-
(2010)
Nitric Oxide
, vol.23
, pp. 75-93
-
-
Pautz, A.1
Art, J.2
Hahn, S.3
Nowag, S.4
Voss, C.5
Kleinert, H.6
-
60
-
-
0345547431
-
Regulation of the expression of inducible nitric oxide synthase
-
Kleinert H, Schwarz PM, Forstermann U. Regulation of the expression of inducible nitric oxide synthase. Biol Chem 2003; 384: 1343-1364.
-
(2003)
Biol Chem
, vol.384
, pp. 1343-1364
-
-
Kleinert, H.1
Schwarz, P.M.2
Forstermann, U.3
-
61
-
-
78649767464
-
Reciprocal activation of macrophages and breast carcinoma cells by nitric oxide and colony-stimulating factor-1
-
Lin CW, Shen SC, Ko CH, Lin HY, Chen YC. Reciprocal activation of macrophages and breast carcinoma cells by nitric oxide and colony-stimulating factor-1. Carcinogenesis 2010; 31: 2039-2048.
-
(2010)
Carcinogenesis
, vol.31
, pp. 2039-2048
-
-
Lin, C.W.1
Shen, S.C.2
Ko, C.H.3
Lin, H.Y.4
Chen, Y.C.5
-
62
-
-
0028786601
-
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
-
Melillo G, Musso T, Sica A, et al. A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Exp Med 1995; 182: 1683-1693.
-
(1995)
J Exp Med
, vol.182
, pp. 1683-1693
-
-
Melillo, G.1
Musso, T.2
Sica, A.3
-
63
-
-
33746864818
-
Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling
-
Du Q, Park KS, Guo Z, et al. Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling. Cancer Res 2006; 66: 7024-7031.
-
(2006)
Cancer Res
, vol.66
, pp. 7024-7031
-
-
Du, Q.1
Park, K.S.2
Guo, Z.3
-
64
-
-
39149132505
-
Inducible nitric oxide synthase: Correlation with extracapsular spread and enhancement of tumor cell invasion in head and neck squamous cell carcinoma
-
Brennan PA, Dennis S, Poller D, et al. Inducible nitric oxide synthase: correlation with extracapsular spread and enhancement of tumor cell invasion in head and neck squamous cell carcinoma. Head Neck 2008; 30: 208-214.
-
(2008)
Head Neck
, vol.30
, pp. 208-214
-
-
Brennan, P.A.1
Dennis, S.2
Poller, D.3
-
65
-
-
0029024521
-
Nitric oxide synthase activity in human breast cancer
-
Thomsen LL, Miles DW, Happerfield L, et al. Nitric oxide synthase activity in human breast cancer. Brit J Cancer 1995; 72: 41-44.
-
(1995)
Brit J Cancer
, vol.72
, pp. 41-44
-
-
Thomsen, L.L.1
Miles, D.W.2
Happerfield, L.3
-
66
-
-
0034083406
-
Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas
-
Vakkala M, Kahlos K, Lakari E, et al. Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas. Clin Cancer Res 2000; 6: 2408-2416.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2408-2416
-
-
Vakkala, M.1
Kahlos, K.2
Lakari, E.3
-
67
-
-
0031984809
-
Frequent nitric oxide synthase-2 expression in human colon adenomas: Implication for tumor angiogenesis and colon cancer progression
-
Ambs S, Merriam WG, Bennett WP, et al. Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res 1998; 58: 334-341.
-
(1998)
Cancer Res
, vol.58
, pp. 334-341
-
-
Ambs, S.1
Merriam, W.G.2
Bennett, W.P.3
-
68
-
-
33747892706
-
Expression of inducible nitric oxide synthase and cyclooxygenase-2 in angiogenesis and clinical outcome of human gastric cancer
-
Chen CN, Hsieh FJ, Cheng YM, Chang KJ, Lee PH. Expression of inducible nitric oxide synthase and cyclooxygenase-2 in angiogenesis and clinical outcome of human gastric cancer. J Surg Oncol 2006; 94: 226-233.
-
(2006)
J Surg Oncol
, vol.94
, pp. 226-233
-
-
Chen, C.N.1
Hsieh, F.J.2
Cheng, Y.M.3
Chang, K.J.4
Lee, P.H.5
-
69
-
-
0034488632
-
Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma
-
Marrogi AJ, Travis WD, Welsh JA, et al. Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma. Clin Cancer Res 2000; 6: 4739-4744.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4739-4744
-
-
Marrogi, A.J.1
Travis, W.D.2
Welsh, J.A.3
-
70
-
-
78049426509
-
Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients
-
Glynn SA, Boersma BJ, Dorsey TH, et al. Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients. J Clin Invest 2010; 120: 3843-3854.
-
(2010)
J Clin Invest
, vol.120
, pp. 3843-3854
-
-
Glynn, S.A.1
Boersma, B.J.2
Dorsey, T.H.3
-
71
-
-
0028873889
-
Expression of nitric oxide synthase in human central nervous system tumors
-
Cobbs CS, Brenman JE, Aldape KD, Bredt DS, Israel MA. Expression of nitric oxide synthase in human central nervous system tumors. Cancer Res 1995; 55: 727-730.
-
(1995)
Cancer Res
, vol.55
, pp. 727-730
-
-
Cobbs, C.S.1
Brenman, J.E.2
Aldape, K.D.3
Bredt, D.S.4
Israel, M.A.5
-
72
-
-
0028089793
-
Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas
-
Garvey EP, Oplinger JA, Tanoury GJ, et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. J Biol Chem 1994; 269: 26669-26676.
-
(1994)
J Biol Chem
, vol.269
, pp. 26669-26676
-
-
Garvey, E.P.1
Oplinger, J.A.2
Tanoury, G.J.3
-
73
-
-
14644387458
-
1400W, a potent selective inducible NOS inhibitor, improves histopathological outcome following traumatic brain injury in rats
-
Jafarian-Tehrani M, Louin G, Royo NC, et al. 1400W, a potent selective inducible NOS inhibitor, improves histopathological outcome following traumatic brain injury in rats. Nitric Oxide 2005; 12: 61-69.
-
(2005)
Nitric Oxide
, vol.12
, pp. 61-69
-
-
Jafarian-Tehrani, M.1
Louin, G.2
Royo, N.C.3
-
74
-
-
0028848015
-
Isothioureas. potent inhibitors of nitric oxide synthases with variable isoform selectivity
-
Southan GJ, Szabo C, Thiemermann C. Isothioureas. potent inhibitors of nitric oxide synthases with variable isoform selectivity. Brit J Pharmacol 1995; 114: 510-516.
-
(1995)
Brit J Pharmacol
, vol.114
, pp. 510-516
-
-
Southan, G.J.1
Szabo, C.2
Thiemermann, C.3
-
75
-
-
0030859159
-
Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat
-
Iuvone T, Van Osselaer N, D'Acquisto F, Carnuccio R, Herman AG. Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat. Brit J Pharm 1997; 121: 1637-1644.
-
(1997)
Brit J Pharm
, vol.121
, pp. 1637-1644
-
-
Iuvone, T.1
van Osselaer, N.2
D'Acquisto, F.3
Carnuccio, R.4
Herman, A.G.5
-
76
-
-
0027403233
-
Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor NO through a radical reaction
-
Akaike T, Yoshida M, Miyamoto Y, et al. Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor NO through a radical reaction. Biochemistry 1993; 3: 827-832.
-
(1993)
Biochemistry
, vol.3
, pp. 827-832
-
-
Akaike, T.1
Yoshida, M.2
Miyamoto, Y.3
-
77
-
-
0028104024
-
Vasodilator effect of carboxy-2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl in the coronary circulation: In vivo and in vitro studies
-
Tsunoda R, Okumura K, Ishizaka H, et al. Vasodilator effect of carboxy-2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl in the coronary circulation: in vivo and in vitro studies. Eur J Pharm 1994; 262: 55-63.
-
(1994)
Eur J Pharm
, vol.262
, pp. 55-63
-
-
Tsunoda, R.1
Okumura, K.2
Ishizaka, H.3
-
78
-
-
0029129181
-
Discrimination by the NO-trapping agent, carboxy-PTIO, between NO and the nitrergic transmitter but not between NO and EDRF
-
Rand MJ, Li CG. Discrimination by the NO-trapping agent, carboxy-PTIO, between NO and the nitrergic transmitter but not between NO and EDRF. Brit J Pharmacol 1995; 116: 1906-1910.
-
(1995)
Brit J Pharmacol
, vol.116
, pp. 1906-1910
-
-
Rand, M.J.1
Li, C.G.2
-
79
-
-
36448990795
-
Brain tumour stem cells: The undercurrents of human brain cancer and their relationship to neural stem cells
-
Dirks PB. Brain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells. Philos Trans R Soc Lond B Biol Sci 2008; 363: 139-152.
-
(2008)
Philos Trans R Soc Lond B Biol Sci
, vol.363
, pp. 139-152
-
-
Dirks, P.B.1
-
80
-
-
33846485093
-
Brain tumor stem cells: Identification and concepts
-
Singh S, Dirks PB. Brain tumor stem cells: identification and concepts. Neurosurg Clin N Am 2007; 18: 31-38.
-
(2007)
Neurosurg Clin N Am
, vol.18
, pp. 31-38
-
-
Singh, S.1
Dirks, P.B.2
-
81
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature 2004; 432: 396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
82
-
-
33750313208
-
Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells
-
Clarke MF, Dick JE, Dirks PB, et al. Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res 2006, 66: 9339-9344.
-
(2006)
Cancer Res
, vol.66
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
-
83
-
-
33646358694
-
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
-
Lee J, Kotliarova S, Kotliarov Y, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 2006; 9:391-403.
-
(2006)
Cancer Cell
, vol.9
, pp. 391-403
-
-
Lee, J.1
Kotliarova, S.2
Kotliarov, Y.3
-
84
-
-
69849099673
-
Biology of glioma cancer stem cells
-
Park DM, Rich JN. Biology of glioma cancer stem cells. Mol Cells 2009; 28: 7-12.
-
(2009)
Mol Cells
, vol.28
, pp. 7-12
-
-
Park, D.M.1
Rich, J.N.2
-
86
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C, Poppleton H, Kocak M, et al. A perivascular niche for brain tumor stem cells. Cancer Cell 2007; 11: 69-82.
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
-
87
-
-
34648821254
-
Making a tumour's bed: Glioblastoma stem cells and the vascular niche
-
Gilbertson RJ, Rich JN. Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat Rev Cancer 2007; 7: 733-736.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 733-736
-
-
Gilbertson, R.J.1
Rich, J.N.2
-
89
-
-
0032564409
-
Nitrosative stress: Metabolic pathway involving the flavohemoglobin
-
Hausladen A, Gow AJ, Stamler JS. Nitrosative stress: metabolic pathway involving the flavohemoglobin. Proc Natl Acad Sci USA 1998; 95: 14100-14105.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14100-14105
-
-
Hausladen, A.1
Gow, A.J.2
Stamler, J.S.3
-
90
-
-
0030877443
-
Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: Studies with 1400W, a novel inhibitor
-
Thomsen LL, Scott JM, Topley P, et al. Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor. Cancer Res 1997; 57: 3300-3304.
-
(1997)
Cancer Res
, vol.57
, pp. 3300-3304
-
-
Thomsen, L.L.1
Scott, J.M.2
Topley, P.3
-
91
-
-
0032850637
-
Nitric oxide synthase inhibition by N(G)-nitro-L-arginine methyl ester inhibits tumor-induced angiogenesis in mammary tumors
-
Jadeski LC, Lala PK. Nitric oxide synthase inhibition by N(G)-nitro-L-arginine methyl ester inhibits tumor-induced angiogenesis in mammary tumors. Am J Pathol 1999; 155: 1381-1390.
-
(1999)
Am J Pathol
, vol.155
, pp. 1381-1390
-
-
Jadeski, L.C.1
Lala, P.K.2
-
92
-
-
0031018039
-
Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine
-
Tozer GM, Prise VE, Chaplin DJ. Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine. Cancer Res 1997; 57: 948-955.
-
(1997)
Cancer Res
, vol.57
, pp. 948-955
-
-
Tozer, G.M.1
Prise, V.E.2
Chaplin, D.J.3
-
93
-
-
0035284055
-
Genetic disruption of host nitric oxide synthase II gene impairs melanoma-induced angiogenesis and suppresses pleural effusion
-
Wang B, Xiong Q, Shi Q, et al. Genetic disruption of host nitric oxide synthase II gene impairs melanoma-induced angiogenesis and suppresses pleural effusion. Int J Cancer 2001; 91: 607-611.
-
(2001)
Int J Cancer
, vol.91
, pp. 607-611
-
-
Wang, B.1
Xiong, Q.2
Shi, Q.3
-
94
-
-
0035300431
-
Nitric oxide synthase II gene disruption: Implications for tumor growth and vascular endothelial growth factor production
-
Konopka TE, Barker JE, Bamford TL, et al. Nitric oxide synthase II gene disruption: implications for tumor growth and vascular endothelial growth factor production. Cancer Res 2001; 61: 3182-3187.
-
(2001)
Cancer Res
, vol.61
, pp. 3182-3187
-
-
Konopka, T.E.1
Barker, J.E.2
Bamford, T.L.3
-
95
-
-
33846546058
-
Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: A phase I study
-
Ng QS, Goh V, Milner J, et al. Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study. Lancet Oncol 2007; 8: 111-118.
-
(2007)
Lancet Oncol
, vol.8
, pp. 111-118
-
-
Ng, Q.S.1
Goh, V.2
Milner, J.3
-
96
-
-
0035823486
-
SET-related cell division autoantigen-1 (CDA1) arrests cell growth
-
Chai Z, Sarcevic B, Mawson A, Toh BH. SET-related cell division autoantigen-1 (CDA1) arrests cell growth. J Biol Chem 2001; 276: 33665-33674.
-
(2001)
J Biol Chem
, vol.276
, pp. 33665-33674
-
-
Chai, Z.1
Sarcevic, B.2
Mawson, A.3
Toh, B.H.4
-
97
-
-
46949091848
-
Differentially expressed nucleolar transforming growth factor-beta1 target (DENTT) exhibits an inhibitory role on tumorigenesis
-
Kandalaft LE, Zudaire E, Portal-Nunez S, Cuttitta F, Jakowlew SB. Differentially expressed nucleolar transforming growth factor-beta1 target (DENTT) exhibits an inhibitory role on tumorigenesis. Carcinogenesis 2008; 29: 1282-1289.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1282-1289
-
-
Kandalaft, L.E.1
Zudaire, E.2
Portal-Nunez, S.3
Cuttitta, F.4
Jakowlew, S.B.5
-
98
-
-
34249694142
-
Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways
-
Tu Y, Wu W, Wu T, et al. Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways. J Biol Chem 2007; 282: 11722-11731.
-
(2007)
J Biol Chem
, vol.282
, pp. 11722-11731
-
-
Tu, Y.1
Wu, W.2
Wu, T.3
-
99
-
-
33846600845
-
Inflammation and IGF-I activate the Akt pathway in breast cancer
-
Prueitt RL, Boersma BJ, Howe TM, et al. Inflammation and IGF-I activate the Akt pathway in breast cancer. Int J Cancer 2007; 120: 796-805.
-
(2007)
Int J Cancer
, vol.120
, pp. 796-805
-
-
Prueitt, R.L.1
Boersma, B.J.2
Howe, T.M.3
-
102
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
Dimmeler S, Fleming I, Fisslthaler B, et al. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 1999; 399: 601-605.
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
-
103
-
-
0036841293
-
Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage
-
Kandel ES, Skeen J, Majewski N, et al. Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage. Mol Cell Biol 2002; 22: 7831-7841.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7831-7841
-
-
Kandel, E.S.1
Skeen, J.2
Majewski, N.3
-
104
-
-
0034828008
-
Regulation of interleukin-8 expression by nitric oxide in human pancreatic adenocarcinoma
-
Xiong Q, Shi Q, Le X, Wang B, Xie K. Regulation of interleukin-8 expression by nitric oxide in human pancreatic adenocarcinoma. J Interferon Cytokine Res 2001; 21: 529-537.
-
(2001)
J Interferon Cytokine Res
, vol.21
, pp. 529-537
-
-
Xiong, Q.1
Shi, Q.2
Le, X.3
Wang, B.4
Xie, K.5
-
105
-
-
3042784053
-
Nitric oxide post-transcriptionally up-regulates LPS-induced IL-8 expression through p38 MAPK activation
-
Ma P, Cui X, Wang S, et al. Nitric oxide post-transcriptionally up-regulates LPS-induced IL-8 expression through p38 MAPK activation. J Leukoc Biol 2004, 76: 278-287.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 278-287
-
-
Ma, P.1
Cui, X.2
Wang, S.3
-
106
-
-
4544257935
-
Nitric oxide increases IL-8 gene transcription and mRNA stability to enhance IL-8 gene expression in lung epithelial cells
-
Sparkman L, Boggaram V. Nitric oxide increases IL-8 gene transcription and mRNA stability to enhance IL-8 gene expression in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol 2004; 287: L764-773.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Sparkman, L.1
Boggaram, V.2
-
107
-
-
8444230395
-
Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival
-
Benoy IH, Salgado R, Van Dam P, et al. Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. Clin Cancer Res 2004; 10: 7157-7162.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7157-7162
-
-
Benoy, I.H.1
Salgado, R.2
van Dam, P.3
-
108
-
-
79951866285
-
Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer
-
Ambs S, Glynn SA. Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer. Cell Cycle 2011; 10: 619-624.
-
(2011)
Cell Cycle
, vol.10
, pp. 619-624
-
-
Ambs, S.1
Glynn, S.A.2
-
109
-
-
0028046946
-
Cytokine gene expression on glioma cell lines and specimens
-
Yamanaka R, Tanaka R, Saitoh T, Okoshi S. Cytokine gene expression on glioma cell lines and specimens. J Neuro-oncol 1994;21: 243-247.
-
(1994)
J Neuro-oncol
, vol.21
, pp. 243-247
-
-
Yamanaka, R.1
Tanaka, R.2
Saitoh, T.3
Okoshi, S.4
-
110
-
-
1642586297
-
The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
-
Garkavtsev I, Kozin SV, Chernova O, et al. The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis. Nature 2004; 428: 328-332.
-
(2004)
Nature
, vol.428
, pp. 328-332
-
-
Garkavtsev, I.1
Kozin, S.V.2
Chernova, O.3
-
111
-
-
0037424253
-
Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2
-
Heidemann J, Ogawa H, Dwinell MB, et al. Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. J Biol Chem 2003; 278: 8508-8515.
-
(2003)
J Biol Chem
, vol.278
, pp. 8508-8515
-
-
Heidemann, J.1
Ogawa, H.2
Dwinell, M.B.3
-
112
-
-
78650897830
-
The role of tumour-derived iNOS in tumour progression and angiogenesis
-
Kostourou V, Cartwright JE, Johnstone AP, et al. The role of tumour-derived iNOS in tumour progression and angiogenesis. Br J Cancer 2011; 104: 83-90.
-
(2011)
Br J Cancer
, vol.104
, pp. 83-90
-
-
Kostourou, V.1
Cartwright, J.E.2
Johnstone, A.P.3
-
113
-
-
61849083102
-
A highly invasive human glioblastoma pre-clinical model for testing therapeutics
-
Xie Q, Thompson R, Hardy K, et al. A highly invasive human glioblastoma pre-clinical model for testing therapeutics. J Transl Med 2008; 6: 77.
-
(2008)
J Transl Med
, vol.6
, pp. 77
-
-
Xie, Q.1
Thompson, R.2
Hardy, K.3
-
115
-
-
0028803728
-
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
-
Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995; 83: 493-501.
-
(1995)
Cell
, vol.83
, pp. 493-501
-
-
Tsujii, M.1
Dubois, R.N.2
-
116
-
-
80052927442
-
COX-2 regulates the proliferation of glioma stem like cells
-
Sharma V, Dixit D, Ghosh S, Sen E. COX-2 regulates the proliferation of glioma stem like cells. Neurochem Int 2011; 59: 567-571.
-
(2011)
Neurochem Int
, vol.59
, pp. 567-571
-
-
Sharma, V.1
Dixit, D.2
Ghosh, S.3
Sen, E.4
-
117
-
-
0030879456
-
Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: Independence from COX-2 protein expression
-
Elder DJ, Halton DE, Hague A, Paraskeva C. Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression. Clin Cancer Res 1997; 3: 1679-1683.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 1679-1683
-
-
Elder, D.J.1
Halton, D.E.2
Hague, A.3
Paraskeva, C.4
-
118
-
-
0032188853
-
NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells
-
Liu XH, Yao S, Kirschenbaum A, Levine AC. NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells. Cancer Res 1998; 58: 4245-4249.
-
(1998)
Cancer Res
, vol.58
, pp. 4245-4249
-
-
Liu, X.H.1
Yao, S.2
Kirschenbaum, A.3
Levine, A.C.4
-
119
-
-
0034282530
-
Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398
-
Joki T, Heese O, Nikas DC, et al. Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398. Cancer Res 2000; 60: 4926-4931.
-
(2000)
Cancer Res
, vol.60
, pp. 4926-4931
-
-
Joki, T.1
Heese, O.2
Nikas, D.C.3
-
120
-
-
0033194582
-
Patterns of cyclooxygenase-1 and -2 expression in human gliomas in vivo
-
Deininger MH, Weller M, Streffer J, Mittelbronn M, Meyermann R. Patterns of cyclooxygenase-1 and -2 expression in human gliomas in vivo. Acta Neuropathol 1999; 98: 240-244.
-
(1999)
Acta Neuropathol
, vol.98
, pp. 240-244
-
-
Deininger, M.H.1
Weller, M.2
Streffer, J.3
Mittelbronn, M.4
Meyermann, R.5
-
121
-
-
77249132723
-
Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes
-
Lo HW, Cao X, Zhu H, Ali-Osman F. Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes. Mol Cancer Res 2010; 8: 232-245.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 232-245
-
-
Lo, H.W.1
Cao, X.2
Zhu, H.3
Ali-Osman, F.4
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