Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat

British Journal of Pharmacology

Volumn 121, Issue 8, 1997, Pages 1637-1644

  Iuvone, Teresa ^a,b   Van Osselaer, Nancy ^a   D'Acquisto, Fulvio ^b   Carnuccio, Rosa ^b   Herman, Arnold G ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Carrageenin; L NAME; Leukocyte emigration; Lymphocytes; MCP 1; Nitric oxide; Phenylephrine; PMNs; Prostacyclin; S methyl isothiourea; Sponge implants; TNF

Indexed keywords

ARGININE; CARRAGEENAN; DEXTRO ARGININE; MONOCYTE CHEMOTACTIC PROTEIN 1; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRITE; PHENYLEPHRINE; PROSTACYCLIN; S METHYLPSEUDOTHIOUREA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; EXUDATE; IMPLANT; INFLAMMATION; LEUKOCYTE MIGRATION; LYMPHOCYTIC INFILTRATION; MALE; NEUTROPHIL; NONHUMAN; ORAL DRUG ADMINISTRATION; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; RAT; SPONGE;

ANIMALS; ARGININE; CAPILLARY PERMEABILITY; CARRAGEENAN; CELL MOVEMENT; ENZYME INHIBITORS; EPOPROSTENOL; INFLAMMATION; ISOTHIURONIUM; LEUKOCYTES; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITES; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030859159     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701317     Document Type: Article

References (44)

1. ARNDT, H., RUSSELL, J.M., KUROSE, I., KUBES, P. & GRANGER, D.N. (1993). Mediators of leukocyte adhesion in rat mesenteric venules elicited by inhibition of nitric oxide synthesis. Gastroenterology, 105, 675-680.
2. BAGGIOLINI, M., DEWALD, B. & MOSER, B. (1994). Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv. Immunol., 55, 97-179.
3. G-nitro-L-arginine methyl ester to the rat on inhibition of nitric oxide-mediated responses. Br. J. Pharmacol., 114, 1673-1679.
4. BUTCHER, E.C. (1991). Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell, 67, 1033-1036.
5. CARR, M.W., ROTH, S.J., LUTHER, E., ROSE, S.S. & SPRINGER, T.A. (1994). Monocyte chemoattractant protein-1 acts as a T-lymphocyte chemoattractant. Proc. Natl. Acad. Sci. U.S.A., 91, 3652-3656.
6. DI ROSA, M., IALENTI, A., IANARO, A. & SAUTEBIN, L. (1996). Interaction between nitric oxide and cyclooxygenase pathways. Prostaglandins, Leukotrienes Essential Fatty Acids, 54, 229-238.
7. DONI, M.G., WHITTLE, B.J.R., PALMER, R.M.J. & MONCADA, S. (1988). Actions of nitric oxide on the release of prostacyclin from bovine endotheliat cells in culture. Eur. J. Pharmacol., 151, 19-25.
8. DUDLEY, R.A., EDWARDS, P., ELKINS, R.P., FINNEY, D.J., MCKENZIE, I.G.M., RAAB, G.M., RODBARD, D. & RODGERS, R.P.C. (1985). Guidelines for immunoassay data processing. Clin. Chem., 31, 1264-1271.
9. EIGLER, A., MOELLER, J. & ENDRES, S. (1995). Exogenous and endogenous nitric oxide attenuates tumor necrosis factor synthesis in the murine macrophage cell line RAW 264.7. J. Immunol., 154, 4048-4054.
10. G-nitro-L-arginine methyl ester in conscious, Long Evans rats. Br. J. Pharmacol., 101, 625-631.
11. GARRELDS, I.M., ZIJLSTRA, F.J., TAK, C.J.A.M., BONTA, I.L., BECKMAN, I. & BEN-EFRAIM, S. (1993). A comparison between two methods for measuring tumor necrosis factor in biological fluids. Agents Actions, 38, C90-91.
12. GAUTHIER, T.W., DAVENPECK, K.L. & LEFER, A.M. (1994). Nitric oxide attenuates leukocyte-endothelial interaction via P-selectin in splanchnic ischemia-reperfusion. Am. J. Physiol., 267, G562-G568.
13. HALE, S.L. & KLONER, R.A. (1994). Protection of myocardium by transient preischemic administration of phenylephrine to the rabbit. Coron. Artery Dis., 5, 605-610.
14. IALENTI, A., IANARO, A., MONCADA, S. & DI ROSA, M. (1992). Modulation of acute inflammation by endogenous nitric oxide. Eur. J. Pharmacol., 211, 177-182.
15. IALENTI, A., MONCADA, S. & DI ROSA, M. (1993). Modulation of adjuvant arthritis by endogenous nitric oxide. Br. J. Pharmacol., 110, 701-706.
16. ISSEKUTZ, A.C. (1981). Effect of vasoactive agents on polymorphonuclear leukocyte emigration in vivo. Lab. Invest., 45, 23-24.
17. IUVONE, T., CARNUCCIO, R. & DI ROSA, M. (1994). Modulation of granuloma formation by endogenous nitric oxide. Eur. J. Pharmacol., 265, 89-92.
18. IUVONE, T., D'ACQUISTO, F., CARNUCCIO, R. & DI ROSA, M. (1996). Nitric oxide modulates LPS-induced TNF-α synthesis in vivo and in vitro. Life Sci., 59, PL 207-211.
19. KEEN, M., PICKERING, S.A.W. & HUNT, J.A. (1990). Modulation of bradykinin-stimulated release of prostacyclin from endothelial cells. Br. J. Pharmacol., 101, 524P.
20. KUBES, P., SUZUKI, M. & GRANGER, D.N. (1991). Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. U.S.A., 88, 4651-4655.
21. KUBES, P., KZANWARS, S., NIU, X.F. & GABOURY, J.P. (1993). Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells. FASEB J., 7, 1293-1299.
22. LAEKEMAN, G.M., VERGOTE, I.B., KEERSMAEKERS, G.M., HEIREMANS, J., HAENSCH, C.F., DE ROY G., UYTTENBROECK, F.L. & HERMAN, A.G. (1986). Prostacyclin and thromboxane in benign and malignant breast tumors. Br. J. Cancer, 54, 431-437.
23. MARTICH, G.D., DANNER, R.L., CESKA, M. & SUFFREDINI, A.F. (1991). Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents. J. Exp. Med., 173, 1021-1024.
24. MCCALL, T., WHITTLE, B.J.R., BOUGHTON-SMITH, N.K. & MONCADA, S. (1988). Inhibition of FMLP-induced aggregation of rabbit neutrophils by nitric oxide. Br. J. Pharmacol., 95, 517P.
25. MCCARTNEY-FRANCIS, M., HALLEN, H.B., MIZEL, D.E., ALBINA, J.E., XIE, Q.W., NATHAN, C.F. & WAHL, S.M. (1993). Suppression of arthritis by an inhibitor of nitric oxide synthase. J. Exp. Med., 178, 794-754.
26. MONCADA, S., PALMER, R.M.J. & HIGGS, E.A. (1991). Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev., 43, 109-142.
27. MORRIS, Jr, S.M. & BILLIAR, T.R. (1994). New insights into the regulation of inducible nitric oxide synthesis. Am. J. Physiol 226, E829-E839.
28. OSBORN, L. (1990). Leukocyte adhesion to endothelium in inflammation. Cell, 62, 3-6.
29. PETTIPHER, E.R. & WIMBERLY, D.J. (1994). Cyclooxygenase inhibitors enhance tumour necrosis factor production and mortality in murine endotoxic shock. Cytokine, 6, 500-503.
30. RAMPART, M., DE SMET, W., FIERS, W. &. HERMAN, A.G. (1989). Inflammatory properties of recombinant tumor necrosis factor in rabbit skin in vivo. J. Exp. Med., 169, 2227-2232.
31. SALVEMINI, D., MANNING, P.T., ZWEIFEL, B.S., SEIBERT, K., CONNOR, J., CURRIE, M.G., NEEDLEMAN, P. & MASFERRER, J.L. (1995). Dual inhibition of nitric oxide and prostaglandin production contributes to the anti-inflammatory properties of nitric oxide synthase inhibitors. J. Clin. Invest., 96, 301-308.
32. SALVEMINI, D., MISKO, T.P., MASFERRER, J., SEIBERT, K., CURRIE, M.G. & NEEDLEMAN, P. (1993). Nitric oxide activates cyclooxygenase enzymes. Proc. Natl. Acad. Sci. U.S.A., 90, 7240-7244.
33. SAUTEBIN, L., IALENTI, A., IANARO, A. & DI ROSA, M. (1995). Modulation by nitric oxide of prostaglandin biosynthesis in the rat. Br. J. Pharmacol., 114, 323-328.
34. SCHMIDT, H.H.H.W., NAU, H., WITTFOHT, W., GERLACH, J., PRESCHER, E., KLEIN, MNIROOMAND, F. & BOHME, E. (1988). Arginine is a physiological precursor of endothelium-derived nitric oxide. Eur. J. Pharmacol., 154, 213-216.
35. SOUTHAN, G.J., SZABO, C. & THIEMERMANN, C. (1995). Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity. Br. J. Pharmacol., 114, 510-516.
36. SPRINGER, T.A. (1990). Adhesion receptors of the immune system. Nature, 346, 425-434.
37. STADLER, J., HARBRECHT, B.G., DI SILVIO, M., CURRAN, R.D., JORDAN, M.L., SIMMONS, R.L. & BILLIAR, T.R. (1993). Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells. J. Leukoc. Biol., 53, 165-172.
38. SZABO, C., SOUTHAN, G.J. & THIEMERMANN, C. (1994). Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. Proc. Natl. Acad. Sci. U.S.A., 91, 12472-12476.
39. TAUB, D.D., PROOST, P., MURPHY, W.J., ANVER, M., LONGO, D.L., VAN DAMME, J. & OPPENHEIM, J.J. (1995). Monocyte chemotactic protein-1 (MCP-1), -2, and -3 arechemotactic for human T lymphocytes. J. Clin. Invest., 95, 1370-1376.
40. VASQUEZ, E.C., CHUNA, R.S. & CABRAL, A.M. (1994). Baroreceptors reflex function in rats submitted to chronic inhibition of nitric oxide synthesis. Braz. J. Med. Biol. Res., 27, 767-774.
41. WILLIAMS, T.J. (1977). Chemical mediators of vascular responses in inflammation: a two mediator hypothesis. Br. J. Pharmacol., 61, 477P.
42. WILLIAMS, T.J., (1983). Interactions between prostaglandins, leukotrienes and other mediators of inflammation. Br. Med. Bull., 39, 239-242.
43. WUYTS, A., PROOST, P., PUT, W., LENAERTS, J.P., PAEMEN, L. & VAN DAMME, J. (1994). Leukocyte recruitment by monocyte chemotactic proteins (MCPs) secreted by human phagocytes. J. Immunol. Methods, 174, 237-274.
44. ZEIHER, A.M., FISSLTHALER, B., SCHRAY-UTZ, B. & BUSSE, R. (1995). Nitric oxide modulates the expression of monocyte chemoattractant protein 1 in cultured human endothelial cells. Circ. Res., 76, 980-986.